Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719

British Journal of Pharmacology

Volumn 124, Issue 6, 1998, Pages 1300-1306

  Thomas, David R ^a   Gittins, Susan A ^a   Collin, Lissa L ^a   Middlemiss, Derek N ^a   Riley, Graham ^a   Hagan, Jim ^a   Gloger, Israel ^a   Ellis, Catherine E ^a   Forbes, Ian T ^a   Brown, Anthony M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

3H 5 CT binding; Adenylyl cyclase; Constitutive receptor activity; Functional characterisation; Human 5 HT(7(a)) receptor; Inverse agonism; Long splice variant; SB 258719

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3,N DIMETHYL N [1 METHYL 3 (4 METHYL 1 PIPERIDINYL)PROPYL]BENZENESULFONAMIDE; 5 CARBAMOYLTRYPTAMINE; ADENYLATE CYCLASE; CLOZAPINE; KETANSERIN; MESULERGINE; METITEPINE; OLANZAPINE; RISPERIDONE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR AFFINITY;

ADENYLATE CYCLASE; CELL LINE; CLONING, MOLECULAR; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; PIPERIDINES; PROTEIN BINDING; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN ANTAGONISTS; SULFONAMIDES;

EID: 15144342436     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701946     Document Type: Article

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