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Volumn 44, Issue 23, 2001, Pages 3881-3895

N-arylsulfonylindole derivatives as serotonin 5-HT6 receptor ligands

(10) Russell, M G N a Baker, R J a Barden, L a Beer, M S a Bristow, L a Broughton, H B a Knowles, M a McAllister, G a Patel, S a Castro, J L a

a NEUROSCIENCE RESEARCH CENTRE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4,5 TETRAHYDROBENZ[C,D]INDOLE; 3 (3 METHOXYBENZYL) 1,2,4 OXADIAZOL 5 YL; 4 (AMINOETHYL)INDOLE DERIVATIVE; 5 METHOXY 1 BENZENESULFONYL; ADENYLATE CYCLASE; DOPAMINE RECEPTOR; INDOLE DERIVATIVE; LIGAND; SEROTONIN 5 RECEPTOR; SEROTONIN RECEPTOR; SULFONYLINDOLE DERIVATIVE; SULFONYLTRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; DRUG ACTIVITY; ENERGY; ENZYME ACTIVATION; HEAD TWITCH; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; RAT; RECEPTOR BINDING;

ANIMALS; BEHAVIOR, ANIMAL; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; HELA CELLS; HUMANS; INDOLES; LIGANDS; MALE; MESCALINE; MODELS, MOLECULAR; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN AGENTS; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES;

EID: 0035829428 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm010943m Document Type: Article

Times cited : (115)

References (35)

1
- 0028183017
- International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
- (1994) Pharmacol. Rev. , vol.46 , pp. 157-204
- Hoyer, D.¹ Clarke, D.E.² Fozard, J.R.³ Hartig, P.R.⁴ Martin, G.R.⁵ Mylecharane, E.⁶ Saxena, P.R.⁷ Humphrey, P.P.A.⁸

2
- 0027481384
- Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
- (1993) Mol. Pharmacol. , vol.43 , pp. 320-327
- Monsma, F.J.¹ Shen, Y.² Ward, R.P.³ Hamblin, W.⁴ Sibley, D.R.⁵

3
- 0027212940
- 6) receptor: Molecular cloning, localisation and stimulation of cAMP accumulation
- (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 269276
- Ruat, M.¹ Traiffort, E.² Arrang, J.-M.³ Tardivel-Lacombe, J.⁴ Diaz, J.⁵ Leurs, R.⁶ Swartz, J.-C.⁷

4
- 13344275875
- 6 serotonin receptor
- (1996) J. Neurochem. , vol.66 , pp. 47-56
- Kohnen, R.¹ Metcalf, M.A.² Khan, N.³ Druck, T.⁴ Huebner, K.⁵ Lachowicz, J.E.⁶ Meltzer, H.⁷ Sibley, D.R.⁸ Roth, B.L.⁹ Hamblin, M.W.¹⁰

5
- 0028896011
- Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry
- (1995) Neuroscience , vol.64 , pp. 1105-1111
- Ward, R.P.¹ Hamblin, M.W.² Lachowicz, J.E.³ Hoffman, B.J.⁴ Sibley, D.R.⁵ Dorsa, D.M.⁶

6
- 0033625757
- 6 receptors as emerging targets for drug discovery
- (2000) Annu. Rev. Pharmacol. Toxicol. , vol.40 , pp. 319-334
- Branchek, T.A.¹ Blackburn, T.P.²

7
- 0028981113
- 6 receptor in the rat brain: A study using antisense oligonucleotides
- (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 173-180
- Bourson, A.¹ Borroni, E.² Austin, R.H.³ Monsma, F.J.⁴ Sleight, A.J.⁵

8
- 0032571283
- 6 receptor subtype in the rat brain
- (1998) Life Sci. , vol.62 , pp. 1473-1477
- Yoshioka, M.¹ Matsumoto, M.² Togashi, H.³ Mori, K.⁴ Saito, H.⁵

9
- 0031748656
- 6 receptors
- (1998) Br. J. Pharmacol. , vol.124 , pp. 556-562
- Sleight, A.J.¹ Boess, F.G.² Bös, M.³ Levet-Trafit, B.⁴ Riemer, C.⁵ Bourson, A.⁶

10
- 0032960693
- 6 receptor antagonist
- (1999) J. Med. Chem. , vol.42 , pp. 202-205
- Bromidge, S.M.¹ Brown, A.M.² Clarke, S.E.³ Dodgson, K.⁴ Gager, T.⁵ Grassam, H.L.⁶ Jeffrey, P.M.⁷ Joiner, G.F.⁸ King, F.D.⁹ Middlemiss, D.N.¹⁰ Moss, S.F.¹¹ Newman, H.¹² Riley, G.¹³ Routledge, C.¹⁴ Wyman, P.¹⁵

11
- 0031593618
- 6 receptors in nigro-striatal function in rodents
- (1998) Br. J. Pharmacol. , vol.125 , pp. 1562-1566
- Bourson, A.¹ Boess, F.G.² Bös, M.³ Sleight, A.J.⁴

12
- 0032907531
- 6 receptor antagonist, Ro 04-6790, in rats
- (1999) Br. J. Pharmacol. , vol.126 , pp. 1537-1542
- Bentley, J.C.¹ Bourson, A.² Boess, F.G.³ Fone, K.C.F.⁴ Marsden, C.A.⁵ Petit, N.⁶ Sleight, A.J.⁷

13
- 0034098959
- 6 antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate
- (2000) Br. J. Pharmacol. , vol.130 , pp. 23-26
- Dawson, L.A.¹ Nguyen, H.Q.² Li, P.³

14
- 0033854822
- 6 receptor antagonist
- (2000) Br. J. Pharmacol. , vol.130 , pp. 1606-1612
- Routledge, C.¹ Bromidge, S.M.² Moss, S.F.³ Price, G.W.⁴ Hirst, W.⁵ Newman, H.⁶ Riley, G.⁷ Gager, T.⁸ Stean, T.⁹ Upton, N.¹⁰ Clarke, S.E.¹¹ Brown, A.M.¹² Middlemiss, D.N.¹³

15
- 0035825334
- 6 Antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)
- (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 55-58
- Bromidge, S.M.¹ Clarke, S.E.² Gager, T.³ Griffith, K.⁴ Jeffrey, P.⁵ Jennings, A.J.⁶ Joiner, G.F.⁷ King, F.D.⁸ Lovell, P.J.⁹ Moss, S.F.¹⁰ Newman, H.¹¹ Riley, G.¹² Rogers, D.¹³ Routledge, C.¹⁴ Serafinowska, H.¹⁵ Smith, D.R.¹⁶

16
- 0034675393
- 6 antagonists
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 2295-2299
- Tsai, Y.¹ Dukat, M.² Slassi, A.³ MacLean, N.⁴ Demchyshyn, L.⁵ Savage, J.E.⁶ Roth, B.L.⁷ Hufesein, S.⁸ Lee, M.⁹ Glennon, R.A.¹⁰

17
- 0034487697
- 1-benzenesulfonyl and related tryptamines
- (2000) Med. Chem. Res. , vol.10 , pp. 230-242
- Lee, M.¹ Rangisetty, J.B.² Dukat, M.³ Slassi, A.⁴ Maclean, N.⁵ Lee, D.K.H.⁶ Glennon, R.A.⁷

18
- 0006509163
- U.S. Patent 6,133,287, 2000
- 6 Receptor Inhibitors
- Slassi, A.¹ Edwards, L.² O'Brien, A.³ Xin, T.⁴ Tehim, A.⁵

19
- 0027973162
- 1D receptor
- (1994) J. Med. Chem. , vol.37 , pp. 3023-3032
- Castro, J.L.¹ Baker, R.² Guiblin, A.R.³ Hobbs, S.C.⁴ Jenkins, M.R.⁵ Russell, M.G.N.⁶ Beer, M.S.⁷ Stanton, J.A.⁸ Scholey, K.⁹ Hargreaves, R.J.¹⁰ Graham, M.I.¹¹ Matassa, V.G.¹²

20
- 84985683761
- A new route to tryptamines
- (1974) Synthesis , pp. 354-356
- Szantay, C.¹ Szabo, L.² Kalaus, G.³

21
- 0027246318
- 1D receptors
- (1993) J. Med. Chem. , vol.36 , pp. 1529-1538
- Street, L.J.¹ Baker, R.² Castro, J.L.³ Chambers, M.S.⁴ Guiblin, A.R.⁵ Hobbs, S.C.⁶ Matassa, V.G.⁷ Reeve, A.J.⁸ Beer, M.S.⁹ Middlemiss, D.N.¹⁰ Noble, A.J.¹¹ Stanton, J.A.¹² Scholey, K.¹³ Hargreaves, R.J.¹⁴

22
- 0030300023
- 1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates
- (1996) J. Med. Chem. , vol.39 , pp. 4717-4726
- Barf, T.A.¹ De Boer, P.² Wikstroem, H.³ Peroutka, S.J.⁴ Svensson, K.A.⁵ Ennis, M.D.⁶ Ghazal, N.B.⁷ McGuire, J.C.⁸ Smith, M.W.⁹

23
- 0021323692
- 6-Hydroxy-4-[2-(di-n-propylamino)ethyl]indole: Synthesis and dopaminergic actions
- (1984) J. Med. Chem. , vol.27 , pp. 386-389
- Cannon, G.¹ Lee, T.² Ilhan, M.³ Koons, J.⁴ Long, J.P.⁵

24
- 0019157710
- New synthesis and some selected reactions of the potential ergot alkaloid precursor indole-4-carboxaldehyde
- (1980) J. Org. Chem. , vol.45 , pp. 3350-3352
- Kozikowski, A.P.¹ Ishida, H.² Chen, Y.-Y.³

25
- 37049122105
- 1,3,4,5-Tetrahydrobenz[cd]indoles and related compounds. Part III
- (1973) J. Chem. Soc., Perkin Trans. 1 , pp. 438-442
- Bowman, R.E.¹ Evans, D.D.² Guyett, J.³ Nagy, H.⁴ Weale, J.⁵ Weyell, D.J.⁶

26
- 0032912621
- 6 serotonin receptor binding of indolealkylamines: A preliminary structure-affinity investigation
- (1999) Med. Chem. Res. , vol.9 , pp. 108-117
- Glennon, R.A.¹ Bondarev, M.² Roth, B.³

27
- 0034624773
- 6 serotonin receptors
- (2000) J. Med. Chem. , vol.43 , pp. 1011-1018
- Glennon, R.A.¹ Lee, M.² Rangisetty, J.B.³ Dukat, M.⁴ Roth, B.L.⁵ Savage, J.E.⁶ McBride, A.⁷ Rauser, L.⁸ Hufeisen, S.⁹ Lee, D.K.H.¹⁰

28
- 0027336957
- 1D receptor
- (1993) J. Med. Chem. , vol.36 , pp. 1918-1919
- King, F.D.¹ Brown, A.M.² Gaster, L.M.³ Kaumann, A.J.⁴ Medhurst, A.D.⁵ Parker, S.G.⁶ Parsons, A.A.⁷ Patch, T.L.⁸ Raval, P.⁹

29
- 0006464379
- note

30
- 0033529045
- SQ: A program for rapidly producing pharmacophorically relevant molecular superpositions
- (1999) J. Med. Chem. , vol.42 , pp. 1505-1514
- Miller, M.D.¹ Sheridan, R.P.² Kearsley, S.K.³

31
- 0031722106
- 6 receptor
- (1998) J. Neurochem. , vol.71 , pp. 2169-2177
- Boess, F.G.¹ Monsma F.J., Jr.² Sleight, A.J.³

32
- 0024578313
- Involvement of 5-HT receptor subtypes in the discriminative stimulus properties of mescaline
- (1989) Eur. J. Pharmacol. , vol.159 , pp. 41-46
- Appel, J.B.¹ Callahan, P.M.²

33
- 0028987495
- 1A agonists
- (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 101-112
- Schreiber, R.¹ Brocco, M.² Audinot, V.³ Gobert, A.⁴ Veiga, S.⁵ Millan, M.J.⁶

34
- 0027716547
- 2-Substituted 5-methoxy-N-acyltryptamines: Synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity
- (1993) J. Med. Chem. , vol.36 , pp. 4069-4074
- Spadoni, G.¹ Stankov, B.² Duranti, A.³ Biella, G.⁴ Lucini, V.⁵ Salvatori, A.⁶ Fraschini, F.⁷

35
- 0006422845
- B. P. Feuston, M. D. Miller, J. C. Culbertson, R. B. Nachbar, and S. K. Kearsley, unpublished results

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