SCOPUS 정보 검색 플랫폼

Volumn 45, Issue 11, 2002, Pages 2197-2206

2a-[4-(tetrahydropyridoindol-2-yl)butyl]tetrahydrobenzindole derivatives: New selective antagonists of the 5-hydroxytryptamine7 receptor

(7) Kikuchi, Chika a Ando, Takashi a Watanabe, Takashi a Nagaso, Hiroshi a Okuno, Masayo a Hiranuma, Toyokazu a Koyama, Masao a

a MEIJI SEIKA KAISHA LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2A [4 (TETRAHYDROPYRIDOINDOL 2 YL)BUTYL]TETRAHYDROBENZINDOLE DERIVATIVE; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS;

CELL LINE; CYCLIC AMP; HUMANS; IMMUNOENZYME TECHNIQUES; INDOLES; MODELS, MOLECULAR; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037161613 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0104264 Document Type: Article

Times cited : (58)

References (32)

1
- 0027282204
- 7 serotonin receptor subtype
- (1993) J. Biol. Chem. , vol.268 , pp. 18200-18204
- Shen, Y.¹ Monsma, F.J.² Metcalf, M.A.³ Jose, P.A.⁴ Hamblin, M.W.⁵ Sibley, D.R.⁶

2
- 0027368668
- 7) implicated in the regulation of mammalian circadian rhythms
- (1993) Neuron , vol.11 , pp. 449-458
- Lovenberg, T.W.¹ Baron, B.M.² De Lecea, L.³ Miller, J.O.⁴ Prosser, R.A.⁵ Rea, M.A.⁶ Foye, P.E.⁷ Rucke, M.⁸ Slone, A.L.⁹ Siegel, B.W.¹⁰ Danielson, P.E.¹¹ Sutcliffe, J.G.¹² Erlander, M.G.¹³

3
- 0027183389
- 7) activating cAMP formation
- (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 8547-8551
- Ruat, M.¹ Traiffort, E.² Leurs, R.³ Tardivel-Lacombe, J.⁴ Diaz, J.⁵ Arrang, L.M.⁶ Schwartz, J.C.⁷

4
- 0027186438
- Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase
- (1993) Mol. Pharmacol. , vol.44 , pp. 229-236
- Plassat, J.-L.¹ Amlaiky, N.² Hen, R.³

5
- 0027421620
- 7) positively linked to adenylate cyclase
- (1993) J. Biol. Chem. , vol.268 , pp. 23422-23426
- Bard, J.A.¹ Zgombick, J.² Adham, N.³ Vaysse, P.⁴ Branchek, T.A.⁵ Weinshank, R.L.⁶

6
- 0028168584
- 7 receptor positively coupled to adenylyl cyclase
- (1994) J. Neurochem. , vol.63 , pp. 456-464
- Tsou, A.-P.¹ Kosaka, A.² Bach, C.³ Zuppan, P.⁴ Yee, C.⁵ Tom, L.⁶ Alvarez, R.⁷ Ramsey, S.⁸ Bonhaus, D.W.⁹ Stefanich, E.¹⁰ Jakeman, L.¹¹ Eglen, R.M.¹² Chan, H.W.¹³

7
- 0028261434
- 7 receptors
- (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 1403-1410
- Roth, B.L.¹ Craigo, S.C.² Choudhary, M.S.³ Uluer, A.⁴ Monsma, F.J.⁵ Shen, Y.⁶ Meltzer, H.Y.⁷ Sibley, D.R.⁸

8
- 0030610194
- 7) receptor isoforms in human and rat produced by alternative splicing: Species differences due to altered intron-exon organization
- (1997) J. Neurochem. , vol.68 , pp. 1372-1381
- Heidmann, D.E.A.¹ Metcalf, M.A.² Kohen, R.³ Hamblin, M.W.⁴

9
- 0030854356
- 7(b))
- (1997) Br. J. Pharmacol. , vol.122 , pp. 126-132
- Jasper, J.R.¹ Kosaka, A.² To, Z.P.³ Chang, D.J.⁴ Eglen, R.M.⁵

10
- 0030767784
- 7 receptor: Cloning and pharmacological characterisation of two receptor variants
- (1997) FEBS Lett. , vol.413 , pp. 489-494
- Stam, N.J.¹ Roesink, C.² Dijcks, F.³ Garritsen, A.⁴ Van Herpen, A.⁵ Olijve, W.⁶

11
- 0029012193
- 7 receptors in guinea pig brain
- (1995) Br. J. Pharmacol. , vol.115 , pp. 107-116
- To, Z.P.¹ Bonhaus, D.W.² Eglen, R.M.³ Jakeman, L.B.⁴

12
- 0029961692
- 7 receptor in rat brain
- (1996) Br. J. Pharmacol. , vol.117 , pp. 657-666
- Gustafson, E.L.¹ Durkin, M.M.² Bard, J.A.³ Zgombick, J.⁴ Branchek, T.A.⁵

13
- 0002133977
- 7 and its mRNA in rat CNS by radioligand binding and in situ hybridization histochemistry
- (1994) Br. J. Pharmacol. , vol.112
- Branchek, T.A.¹ Gustafson, E.L.² Durkin, M.M.³ Bard, J.A.⁴ Weinshank, R.L.⁵

14
- 0028985192
- 7 receptor binding sites in rat hypothalamus: Sensitivity to chronic antidepressant treatment
- (1995) Mol. Pharmacol. , vol.47 , pp. 99-103
- Sleight, A.J.¹ Carolo, C.² Petit, N.³ Zwingelstein, C.⁴ Bourson, A.⁵

15
- 0030058186
- Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster
- (1996) Brain Res. , vol.709 , pp. 88-96
- Sumova, A.¹ Maywood, E.S.² Selvage, D.³ Ebling, F.J.P.⁴ Hastings, M.H.⁵

16
- 0030612784
- 7 receptors mediate serotonergic effects on light-sensitive suprachiasmatic nucleus neurons
- (1997) Brain Res. , vol.755 , pp. 246-254
- Ying, S.-W.¹ Rusak, B.²

17
- 0027345403
- A Clinician's primer on the circadian clock: Its localization, function and resetting
- (1993) Adv. Int. Med. , vol.38 , pp. 81-106
- Schwartz, W.J.¹

18
- 0033594770
- 1A receptors in discrete regions of the circadian timing system in hamsters
- (1999) Brain Res. , vol.829 , pp. 39-45
- Duncan, M.J.¹ Short, J.² Wheeler, D.L.³

19
- 18244431670
- 7 receptor antagonist
- (1998) J. Med. Chem. , vol.41 , pp. 655-657
- Forbes, I.T.¹ Dabbs, S.² Duckworth, D.M.³ Jennings, A.J.⁴ King, F.D.⁵ Lovell, P.J.⁶ Brown, A.M.⁷ Collin, L.⁸ Hagan, J.J.⁹ Middlemiss, D.N.¹⁰ Riley, G.J.¹¹ Thomas, D.R.¹² Upton, N.¹³

20
- 0034628555
- 7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)-phenol (SB-269970)
- (2000) J. Med. Chem. , vol.43 , pp. 342-345
- Lovell, P.J.¹ Bromidge, S.M.² Dabbs, S.³ Duckworth, D.M.⁴ Forbes, I.T.⁵ Jennings, A.J.⁶ King, F.D.⁷ Middlemiss, D.N.⁸ Rahman, S.K.⁹ Saunders, D.V.¹⁰ Collin, L.L.¹¹ Hagan, J.J.¹² Riley, G.J.¹³ Thomas, D.R.¹⁴

21
- 0035953317
- 7 receptor antagonist
- (2001) J. Med. Chem. , vol.41 , pp. 1337-1340
- Linnanen, T.¹ Brisander, M.² Unelius, L.³ Rosqvist, S.⁴ Nordvall, G.⁵ Hacksell, U.⁶ Johansson, A.M.⁷

22
- 0033602216
- 7 receptor
- (1999) J. Med. Chem. , vol.42 , pp. 533-535
- Kikuchi, C.¹ Nagaso, H.² Hiranuma, T.³ Koyama, M.⁴

23
- 0002953363
- Formation of N- and C-substituted derivatives during alkylation of indol-2(3h)-one
- (1972) Can. J. Chem. , vol.50 , pp. 18-23
- Gruda, I.¹

24
- 0006123145
- Meiji Seika Kaisha Ltd. Patent WO 9933804, July 8, 1999

25
- 0020004528
- 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role
- (1982) Mol. Pharmacol. , vol.21 , pp. 301-314
- Leysen, J.E.¹ Niemegeers, C.J.E.² Van Nueten, J.M.³ Laduron, P.M.⁴

26
- 0028342977
- Receptors for 5-hydroxytryptamine: Current perspectives on classification and nomenclature
- (1994) Neuropharmacology , vol.33 , pp. 261-273
- Martin, G.R.¹ Humphrey, P.P.A.²

27
- 0022340287
- 3H]Ketanserin
- (1985) Eur. J. Pharmacol. , vol.118 , pp. 13-23
- Hoyer, D.¹ Engel, G.² Kalkman, H.O.³

28
- 0027330221
- 3 receptors in N1E-115 neuroblastoma cells
- (1993) Eur. J. Pharmacol. , vol.243 , pp. 7-11
- Lummis, S.C.R.¹ Sepulveda, M.I.² Kilpatrick, G.J.³ Baker, J.⁴

29
- 0027180590
- 4 receptors in guinea pig and rat brain
- (1993) Br. J. Pharmacol. , vol.109 , pp. 618-624
- Grossman, C.J.¹ Kilpatrick, G.J.² Bunce, K.T.³

30
- 0027481384
- Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
- (1993) Mol. Pharmacol. , vol.43 , pp. 320-327
- Monsma F.J., Jr.¹ Shen, Y.² Ward, R.P.³ Hamblin, M.W.⁴ Sibley, D.R.⁵

31
- 5544242529
- MMFF VI. MMFF94s option for energy minimization studies
- (1999) J. Comput. Chem. , vol.20 , pp. 720-729
- Halgren, T.A.¹

32
- 0000346375
- 50) of an enzymatic reacion
- (1973) Biochem. Pharmacol. , vol.92 , pp. 881-894
- Cheng, Y.C.¹ Prusoff, W.H.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.