SCOPUS 정보 검색 플랫폼

Volumn 71, Issue 4, 2002, Pages 645-654

Pharmacological profile of SB-357134: A potent, selective, brain penetrant, and orally active 5-HT6 receptor antagonist

(13) Stean, Tania O a Hirst, Warren D a Thomas, David R a Price, Gary W a Rogers, Derek a Riley, Graham a Bromidge, Steven M a Serafinowska, Halina T a Smith, Douglas R a Bartlett, Sarah a Deeks, Nigel a Duxon, Mark a Upton, Neil a

a GLAXOSMITHKLINE (United Kingdom)

Author keywords

5 HT6 receptor; 125I SB 258585; 3H LSD; CAMP; Learning; Maximal electroshock seizure threshold (MEST) test; Memory; Morris water maze; SB 357134

Indexed keywords

CYCLIC AMP; IODINE 125; LYSERGIDE; N (2,5 DIBROMO 3 FLUOROPHENYL) 4 METHOXY 3 PIPERAZIN 1 YLBENZENSULFONAMIDE; SB 258585; SB 357134; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CAUDATE NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG PENETRATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ELECTRIC SHOCK; ENZYME ACTIVITY; HELA CELL; LEARNING; LIGAND BINDING; MALE; MAZE TEST; MEMORY; NONHUMAN; PRIORITY JOURNAL; PUTAMEN; RAT; SEIZURE; SWINE;

ALGORITHMS; ANIMALS; BRAIN; BRAIN CHEMISTRY; COGNITION; CYCLIC AMP; ELECTROSHOCK; EXPLORATORY BEHAVIOR; HUMANS; MALE; MAZE LEARNING; MEMBRANES; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEIZURES; SEROTONIN ANTAGONISTS; SULFONAMIDES; SWINE;

SUS SCROFA;

EID: 0036125527 PISSN: 00913057 EISSN: None Source Type: Journal
DOI: 10.1016/S0091-3057(01)00742-0 Document Type: Article

Times cited : (65)

References (29)

1
- 0032907531
- 6 receptor antagonist, Ro 04-6790, in rats
- (1999) Br J Pharmacol , vol.126 , pp. 1537-1542
- Bentley, J.C.¹ Bourson, A.² Boess, F.G.³ Fone, K.C.F.⁴ Marsden, C.A.⁵ Petit, N.⁶ Sleight, A.J.⁷

2
- 0028981113
- 6 receptors in the rat brain: A study using antisense oligonucleotides
- (1995) J Pharmacol Exp Ther , vol.274 , pp. 173-180
- Bourson, A.¹ Borroni, E.² Austin, R.H.³ Monsma, F.J.⁴ Sleight, A.J.⁵

3
- 0028845059
- Nonlinear regression using spreadsheets
- (1995) Trends Pharmacol Sci , vol.16 , pp. 413-417
- Bowen, W.P.¹ Jerman, J.C.²

4
- 0035825334
- 6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)
- (2001) Bioorg Med Chem Lett , vol.11 , pp. 55-58
- Bromidge, S.M.¹ Clarke, S.E.² Gager, T.³ Griffith, K.⁴ Jeffrey, P.⁵ Jennings, A.J.⁶ Joiner, G.F.⁷ King, F.D.⁸ Lovell, P.J.⁹ Moss, S.F.¹⁰ Newman, H.¹¹ Riley, G.¹² Rogers, D.¹³ Routledge, C.¹⁴ Serafinowska, H.¹⁵ Smith, D.R.¹⁶

5
- 0000346375
- 50) of an enzymatic reaction
- (1973) Biochem Pharmacol , vol.92 , pp. 881-894
- Cheng, Y.C.¹ Prusoff, W.H.²

6
- 0034098959
- 6 antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate
- (2000) Br J Pharmacol , vol.130 , pp. 23-26
- Dawson, L.A.¹ Nguyen, H.Q.² Li, P.³

7
- 0032974197
- Modelling of pharmacodynamic (PK/PD) relationships: Concepts and perspectives
- (1999) Pharm Res , vol.16 , Issue.2 , pp. 176-185
- Derendorf, H.¹ Meibohm, B.²

8
- 0034624773
- 6 serotonin receptors
- (2000) J Med Chem , vol.43 , pp. 1011-1018
- Glennon, R.A.¹ Lee, M.² Rangisetty, J.B.³ Dukat, M.⁴ Roth, B.L.⁵ Savage, J.E.⁶ Mcbride, A.⁷ Rauser, L.⁸ Hufeisen, S.⁹ Lee, D.K.H.¹⁰

9
- 0032819492
- 6 receptors
- (1999) Neuropsychopharmacology , vol.21
- Hamon, M.¹ Doucet, E.² Lefevre, K.³ Miquel, M.C.⁴ Lanfumey, L.⁵ Insausti, R.⁶ Frechilla, D.⁷ Del Rio, J.⁸ Verge, D.⁹

10
- 0033624158
- 6 receptors in rat, pig and human brain tissue
- (2000) Br J Pharmacol , vol.130 , pp. 1597-1605
- Hirst, W.D.¹ Minton, J.A.L.² Bromidge, S.M.³ Moss, S.F.⁴ Latter, A.J.⁵ Riley, G.⁶ Routledge, C.⁷ Middlemiss, D.N.⁸ Price, G.W.⁹

11
- 2042472755
- 6 selective compounds and typical and atypical antipsychotics
- (2000) Br J Pharmacol , vol.131
- Hirst, W.D.¹ Babbs, A.J.² Minton, J.A.L.³ Rogers, D.C.⁴ Moss, S.F.⁵ Bromidge, S.M.⁶ Stean, T.⁷ Price, G.W.⁸

12
- 0034618154
- 6 receptor antagonists
- (2000) Bioorg Med Chem Lett , vol.10 , pp. 1719-1721
- Isaac, M.¹ Slassi, A.² Xin, T.³ Maclean, N.⁴ Wilson, J.⁵ McCallum, K.⁶ Wang, H.⁷ Demchyshyn, L.⁸

13
- 0002332216
- Chemical protection against ionising radiation: I. Sampling methods of screening compounds in radiation protection studies in mice
- (1957) Radiat Res , vol.7 , pp. 1-12
- Kimball, A.W.¹ Burnett, W.T.² Doherty, D.G.³

14
- 13344275875
- 6 serotonin receptor
- (1996) J Neurochem , vol.66 , pp. 47-56
- Kohen, R.¹ Metcalf, M.A.² Khan, N.³ Druck, T.⁴ Huebner, K.⁵ Sibley, D.R.⁶

15
- 0034487697
- 1-benzenesulfonyl and related tryptamines
- (2000) Med Chem Res , vol.10 , Issue.4 , pp. 230-242
- Lee, M.¹ Rangisetty, J.B.² Dukat, M.³ Maclean, N.⁴ Lee, D.K.H.⁵ Glennon, R.A.⁶

16
- 84951384024
- A simplified method of evaluating dose-effect experiments
- (1949) J Pharmacol Exp Ther , vol.96 , pp. 99-113
- Litchfield, J.T.¹ Wilcoxon, F.²

17
- 0035825243
- 6 receptor antagonist Ro 04-6790 on learning consolidation
- (2001) Behav Brain Res , vol.118 , pp. 107-110
- Meneses, A.¹

18
- 0027481384
- Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
- (1993) Mol Pharmacol , vol.43 , pp. 320-327
- Monsma, F.J.¹ Shen, Y.² Ward, R.P.³ Hamblin, M.W.⁴ Sibley, D.R.⁵

19
- 0035154738
- 6 receptor antagonists
- (2001) Curr Opin Invest Drugs , vol.2 , Issue.1 , pp. 104-109
- Reavill, C.¹ Rogers, D.C.²

20
- 0034740154
- 6 receptor antagonists enhance retention of a water maze task in the rat
- (2001) Psychopharmacology , vol.158 , pp. 114-119
- Rogers, D.C.¹ Hagan, J.J.²

21
- 0028261434
- Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
- (1994) J Pharmacol Exp Ther , vol.268 , pp. 1403-1410
- Roth, B.L.¹ Criago, S.C.² Choudhary, M.S.³ Uluer, A.⁴ Monsma, F.J.⁵ Shen, Y.⁶ Meltzer, H.Y.⁷ Sibley, D.R.⁸

22
- 0033854822
- 6 receptor antagonist
- (2000) Br J Pharmacol , vol.130 , Issue.7 , pp. 1606-1612
- Routledge, C.¹ Bromidge, S.M.² Moss, S.F.³ Price, G.W.⁴ Hirst, W.⁵ Newman, H.⁶ Riley, G.⁷ Gager, T.⁸ Stean, T.⁹ Upton, N.¹⁰ Clarke, S.E.¹¹ Brown, A.M.¹² Middlemiss, D.N.¹³

23
- 0027212940
- 6) receptor: Molecular cloning, localization and stimulation of cAMP accumulation
- (1993) Biochem Biophys Res Commun , vol.193 , pp. 268-276
- Ruat, M.¹ Traiffort, E.² Arrang, J.M.³ Tardivel-Lacombe, J.⁴ Diaz, J.⁵ Leurs, R.⁶ Schwartz, J.C.⁷

24
- 13344293715
- 6 expression in the rat: Functional studies using antisense oligonucleotides
- (1996) Behav Brain Res , vol.73 , pp. 245-248
- Sleight, A.J.¹ Monsma, F.J.² Borroni, E.³ Austin, R.H.⁴ Bourson, A.⁵

25
- 0031748656
- 6 receptors
- (1998) Br J Pharmacol , vol.124 , Issue.3 , pp. 556-562
- Sleight, A.J.¹ Boess, F.G.² Bos, M.³ Levettrafit, B.⁴ Riemer, C.⁵ Bourson, A.⁶

26
- 0034675393
- 6 antagonists
- (2000) Bioorg Med Chem Lett , vol.10 , pp. 2295-2299
- Tsai, Y.¹ Dukat, M.² Slassi, A.³ Maclean, N.⁴ Demchyshyn, L.⁵ Savage, J.E.⁶ Roth, B.L.⁷ Hufesein, S.⁸ Lee, M.⁹ Glennon, R.A.¹⁰

27
- 8544253950
- Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalised epileptic seizures
- (1997) Br J Pharmacol , vol.121 , pp. 1679-1686
- Upton, N.¹ Blackburn, T.P.² Campbell, C.A.³ Cooper, D.⁴ Evans, M.L.⁵ Herdon, H.J.⁶ King, P.D.⁷ Ray, A.M.⁸ Stean, T.O.⁹ Chan, W.N.¹⁰ Evans, J.M.¹¹ Thompson, M.¹²

28
- 0028896011
- Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridisation histochemistry
- (1995) Neuroscience , vol.64 , pp. 1105-1111
- Ward, R.P.¹ Hamblin, M.W.² Lachowicz, J.E.³ Hoffman, B.J.⁴ Sibley, D.R.⁵ Dorsa, D.M.⁶

29
- 0034742606
- 6 receptors in retention of spatial learning in the Morris water maze
- (2001) Neuropharmacology , vol.41 , pp. 210-219
- Woolley, M.L.¹ Bentley, J.C.² Sleight, A.J.³ Marsden, C.A.⁴ Fone, K.C.F.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.