SB-656104-A: A novel 5-HT7 receptor antagonist with improved in vivo properties

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 22, 2002, Pages 3341-3344

  Forbes, Ian T ^a   Douglas, Sara ^a   Gribble, Andrew D ^a   Ife, Robert J ^a   Lightfoot, Andrew P ^a   Garner, Ashley E ^a   Riley, Graham J ^a   Jeffrey, Phillip ^a   Stevens, Alexander J ^a   Stean, Tania O ^a   Thomas, David R ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

METHYL GROUP; PHENOL DERIVATIVE; SB 269970 A; SB 656104 A; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; HETEROCYCLIC COMPOUND; INDOLE DERIVATIVE; PYRROLIDINE DERIVATIVE; SB-656104-A; SEROTONIN RECEPTOR; SULFONAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG STRUCTURE; NONHUMAN; RAT; ANIMAL; BLOOD BRAIN BARRIER; CHEMISTRY; COMPARATIVE STUDY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BLOOD-BRAIN BARRIER; HETEROCYCLIC COMPOUNDS; INDOLES; PHENOLS; PROTEIN BINDING; PYRROLIDINES; RATS; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 18644367263     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00690-X     Document Type: Article

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