SCOPUS 정보 검색 플랫폼

Volumn 44, Issue 9, 2001, Pages 1337-1340

Atropisomeric derivatives of 2′,6′-disubstituted (R)-11-phenylaporphine: Selective serotonin 5-HT7 receptor antagonists [2]

(7) Linnanen, T a Brisander, M a Unelius, L a Rosqvist, S a Nordvall, G a Hacksell, U a Johansson, A M a

a ASTRAZENECA R AND D (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; 3,N DIMETHYL N [1 METHYL 3 (4 METHYL 1 PIPERIDINYL)PROPYL]BENZENESULFONAMIDE; APORPHINE DERIVATIVE; DOPAMINE 2 RECEPTOR; SEROTONIN 1A RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; CHIRALITY; CHO CELL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ISOMER; LETTER; NONHUMAN; SEROTONINERGIC SYSTEM;

ANIMALS; APORPHINES; BINDING, COMPETITIVE; BRAIN; CHO CELLS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; MOLECULAR CONFORMATION; RATS; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035953317 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0108505 Document Type: Letter

Times cited : (40)

References (31)

1
- 0017093653
- Apomorphine: Chemistry, pharmacology, biochemistry
- (1976) Int. Rev. Neurobiol. , vol.19 , pp. 225-268
- Colpaert, F.C.¹ Van Bever, W.F.² Leysen, J.E.³

2
- 0021351867
- Aporphine enantiomers. Interactions with D-1 and D-2 dopamine receptors
- (1984) Mol. Pharmacol. , vol.25 , pp. 18-23
- Goldman, M.E.¹ Kebabian, J.W.²

3
- 0027284960
- Preparation and pharmacological evaluation of enantiomers of certain nonoxygenated aporphines - (+)- and (-)-aporphine and (+)- and (-)-10-methylaporphine
- (1993) J. Med. Chem. , vol.36 , pp. 1316-1318
- Cannon, J.G.¹ Raghupathi, R.² Moe, S.T.³ Johnson, A.K.⁴ Long, J.P.⁵

4
- 0029795607
- 1A receptor interactions
- (1996) J. Med. Chem. , vol.39 , pp. 3503-3513
- Hedberg, M.H.¹ Linnanen, T.² Jansen, J.M.³ Nordvall, G.⁴ Hjorth, S.⁵ Unelius, L.⁶ Johansson, A.M.⁷

5
- 0034134233
- 7 receptors: Current knowledge and future prospects
- (2000) Trends Pharm. Sci. , vol.21 , pp. 70-77
- Vanhoenacker, P.¹ Haegeman, G.² Leysen, J.E.³

6
- 18244431670
- 7 receptor antagonist
- (1998) J. Med. Chem. , vol.41 , pp. 655-657
- Forbes, I.T.¹ Dabbs, S.² Duckworth, D.M.³ Jennings, A.J.⁴ King, F.D.⁵ Lovell, P.J.⁶ Brown, A.M.⁷ Collin, L.⁸ Hagan, J.J.⁹ Middlemiss, D.N.¹⁰ Riley, G.J.¹¹ Thomas, D.R.¹² Upton, N.¹³

7
- 0033602216
- 7 receptor
- (1999) J. Med. Chem. , vol.42 , pp. 533-535
- Kikuchi, C.¹ Nagaso, H.² Hiranuma, T.³ Koyama, M.⁴

8
- 0034628555
- 7 antagonist: (R)-3-(2-(2-(4-Methylpiperidin1-yl)ethyl)pyrrolidine-l-sulfonyl)phenol (SB-269970)
- (2000) J. Med. Chem. , vol.43 , pp. 342-345
- Lovell, P.J.¹ Bromidge, S.M.² Dabbs, S.³ Duckworth, D.M.⁴ Forbes, I.T.⁵ Jennings, A.J.⁶ King, F.D.⁷ Middlemiss, D.N.⁸ Rahman, S.K.⁹ Saunders, D.V.¹⁰ Collin, L.L.¹¹ Hagan, J.J.¹² Riley, G.J.¹³ Thomas, D.R.¹⁴

9
- 0034611592
- Derivatives of(R)-1,11-methyleneaporphine: Synthesis, structure, and interactions with G-protein coupled receptors
- (2000) J. Med. Chem. , vol.43 , pp. 1339-1349
- Linnanen, T.¹ Brisander, M.² Unelius, L.³ Sundholm, G.⁴ Hacksell, U.⁵ Johansson, A.M.⁶

10
- 0003733338
- W. A. Benjamin: New York
- (1965) Introduction to Stereochemistry , pp. 78
- Mislow, K.¹

11
- 0003942864
- John Wiley & Sons: New York
- (1994) Stereochemistry of Organic Compounds , pp. 1193
- Eliel, E.L.¹ Wilen, S.H.²

12
- 0017645378
- Synthesis and stereospecific antipsychotic activity of (-)-1-cyclopropylmethyl-4-(3-trifluoromethylthio-5H-dibenzo[a,d] cyclohepten-5-ylidene)-piperidine
- (1977) J. Med. Chem. , vol.20 , pp. 1013-1019
- Remy, D.C.¹ Rittle, K.E.² Hunt, C.A.³ Anderson, P.S.⁴ Arison, B.H.⁵ Engelhardt, E.L.⁶ Hirschmann, R.⁷ Clineschmidt, B.V.⁸ Lotti, V.J.⁹ Bunting, P.R.¹⁰ Ballentine, R.J.¹¹ Papp, N.L.¹² Flataker, L.¹³ Witoslawski, J.J.¹⁴ Stone, C.A.¹⁵

13
- 0018714148
- Synthesis, assignment of absolute configuration, and receptor binding studies relevant to the neuroleptic activities of a series of chiral 3-substituted cyproheptadine atropisomers
- (1979) J. Med. Chem. , vol.22 , pp. 1222-1230
- Randall, W.C.¹ Anderson, P.S.² Cresson, E.L.³ Hunt, C.A.⁴ Lyon, T.F.⁵ Rittle, K.E.⁶ Remy, D.C.⁷ Springer, J.P.⁸ Hirshfield, J.M.⁹ Hoogsteen, K.¹⁰ Williams, M.¹¹ Risley, E.A.¹² Totaro, J.A.¹³

14
- 0003545639
- Plenum Press: New York
- (1993) The Steric Factor in Medicinal Chemistry. Dissymmetric Probes of Pharmacological Receptors , pp. 320-321
- Casy, A.F.¹ Dewar, G.H.²

15
- 15644372975
- 1 receptor antagonists: Determination of the absolute stereochemical requirements
- (1998) J. Med. Chem. , vol.41 , pp. 4232-4239
- Ikeura, Y.¹ Ishichi, Y.² Tanaka, T.³ Fujishima, A.⁴ Murabayashi, M.⁵ Kawada, M.⁶ Ishimaru, T.⁷ Kamo, I.⁸ Doi, T.⁹ Natsugari, H.¹⁰

16
- 0033598446
- 1 receptor antagonists: Synthesis, antagonistic activity, and effects on bladder functions
- (1999) J. Med. Chem. , vol.42 , pp. 3982-3993
- Natsugari, H.¹ Ikeura, Y.² Kamo, I.³ Ishimaru, T.⁴ Ishichi, Y.⁵ Fujishima, A.⁶ Tanaka, T.⁷ Kasahara, F.⁸ Kawada, M.⁹ Doi, T.¹⁰

17
- 2042507954
- Palladium-catalyzed cross-coupling reactions of organoboron compounds
- (1995) Chem. Rev. , vol.95 , pp. 2457-2483
- Miyaura, N.¹ Suzuki, A.²

18
- 0346786657
- Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995-1998
- (1999) J. Organomet. Chem. , vol.576 , pp. 147-168
- Suzuki, A.¹

19
- 85069024944
- note

20
- 85069028076
- note

21
- 84943920736
- Phase annealing in SHELX-90: Direct methods for larger structures
- (1990) Acta Crystallogr. , vol.A46 , pp. 467-473
- Sheldrick, G.M.¹

22
- 0004150157
- University of Göttingen: Germany
- (1993) SHELXL-93, Program for the Refinement of Crystal Structures
- Sheldrick, G.M.¹

23
- 0003429110
- University of Utrecht: Utrecht, The Netherlands
- (1992) PLATON-92, Program for the Analysis of Molecular Geometry
- Spek, A.L.¹

24
- 85069010898
- note

25
- 85069029680
- note

26
- 0003942864
- John Wiley & Sons: New York
- (1994) Stereochemisty of Organic Compounds , pp. 1119-1190
- Eliel, E.L.¹ Wilen, S.H.²

27
- 0027322597
- 3 receptors
- (1993) Mol. Pharmacol. , vol.43 , pp. 749-754
- Malmberg, Å.¹ Jackson, D.M.² Eriksson, A.³ Mohell, N.⁴

28
- 0028819386
- Time-course of bromocriptine induced excitation in the rat: Behavioral and biochemical studies
- (1995) Naunyn-Schmiedebergs Arch. Pharmacol. , vol.351 , pp. 146-155
- Jackson, D.M.¹ Mohell, N.² Georgiev, J.³ Bengtsson, A.⁴ Larsson, L.-G.⁵ Magnusson, O.⁶ Ross, S.B.⁷

29
- 85069021796
- Manuscript in preparation
- Studies of Selective Serotonergic Derivatives of (R)-11-Phenylaporphine
- Linnanen, T.¹ Nordvall, G.² Mohell, N.³ Leonova, I.⁴ Johansson, A.M.⁵

30
- 84986437005
- Macromodel - An integrated software system for modeling organic and bioorganic molecules using molecular mechanics
- (1990) J. Comput. Chem. , vol.11 , pp. 440-467
- Mohamadi, F.¹ Richards, N.G.J.² Guida, W.C.³ Liskamp, R.⁴ Lipton, M.⁵ Caufield, C.⁶ Chang, G.⁷ Hendrickson, T.⁸ Still, W.C.⁹

31
- 85069034524
- note

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