-
1
-
-
0023301838
-
The biology of cancer metastasis and implications for therapy
-
Fidler IJ, Balch CM. The biology of cancer metastasis and implications for therapy. Curr Probl Surg 1987; 24: 137-209.
-
(1987)
Curr Probl Surg
, vol.24
, pp. 137-209
-
-
Fidler, I.J.1
Balch, C.M.2
-
3
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain RK. Barriers to drug delivery in solid tumors. Sci Am 1994; 271: 58-65.
-
(1994)
Sci Am
, vol.271
, pp. 58-65
-
-
Jain, R.K.1
-
4
-
-
0023061971
-
Biologic heterogeneity of cancer metastases
-
Fidler IJ. biologic heterogeneity of cancer metastases. Breast Cancer Res Treat 1987; 9: 17-26.
-
(1987)
Breast Cancer Res Treat
, vol.9
, pp. 17-26
-
-
Fidler, I.J.1
-
5
-
-
0018369716
-
Cancer metastasis: A product of tumor - Host interactions
-
Sugarbaker EV. Cancer metastasis: A product of tumor - host interactions. Curr Probl Cancer 1979; 3: 1-59.
-
(1979)
Curr Probl Cancer
, vol.3
, pp. 1-59
-
-
Sugarbaker, E.V.1
-
6
-
-
0026438280
-
Biomechanical interactions of cancer cells with the microvasculature during hematogenous metastasis
-
Weiss L. Biomechanical interactions of cancer cells with the microvasculature during hematogenous metastasis. Cancer Metastasis Rev 1992; 11: 227-35.
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 227-235
-
-
Weiss, L.1
-
7
-
-
0025083071
-
Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes Memorial Award Lecture
-
Fidler IJ. Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes Memorial Award Lecture. Cancer Res 1990; 50: 6130-38.
-
(1990)
Cancer Res
, vol.50
, pp. 6130-6138
-
-
Fidler, I.J.1
-
8
-
-
0022480660
-
Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements
-
Price JE, Aukerman SL, Fidler IJ. Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements. Cancer Res 1986; 46: 5172-8.
-
(1986)
Cancer Res
, vol.46
, pp. 5172-5178
-
-
Price, J.E.1
Aukerman, S.L.2
Fidler, I.J.3
-
9
-
-
0022529711
-
Different deficiencies in the prevention of tumorigenic-low metastatic murine K-1735 melanoma cells from producing metastases
-
Aukerman SL, Price JE, Fidler IJ. Different deficiencies in the prevention of tumorigenic-low metastatic murine K-1735 melanoma cells from producing metastases. J Natl Cancer Inst 1986; 77: 915-24.
-
(1986)
J Natl Cancer Inst
, vol.77
, pp. 915-924
-
-
Aukerman, S.L.1
Price, J.E.2
Fidler, I.J.3
-
10
-
-
0034443811
-
Metastasis of cancer: A conceptual history from antiquity to the 1990s
-
Weiss L. Metastasis of cancer: A conceptual history from antiquity to the 1990s. Cancer Metastasis Rev 2000, 19: I-XI, 193-383.
-
(2000)
Cancer Metastasis Rev
, vol.19
-
-
Weiss, L.1
-
11
-
-
0027333411
-
Tumor cell interactions with the extracellular matrix during invasion and metastasis
-
Stetler-Stevenson WG, Aznavoorian S, Liotta LA. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 1993; 9: 541-73.
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 541-573
-
-
Stetler-Stevenson, W.G.1
Aznavoorian, S.2
Liotta, L.A.3
-
12
-
-
0026425631
-
Tumor invasion and metastasis: An imbalance of positive and negative regulation
-
Liotta LA, Stetler-Stevenson WG. Tumor invasion and metastasis: An imbalance of positive and negative regulation. Cancer Res 1991; 51: 5054s-59s.
-
(1991)
Cancer Res
, vol.51
-
-
Liotta, L.A.1
Stetler-Stevenson, W.G.2
-
13
-
-
0026572472
-
Autocrine motility factor and its receptor: Role in cell locomotion and metastasis
-
Nabi IR, Watanabe H, Raz A. Autocrine motility factor and its receptor: Role in cell locomotion and metastasis. Cancer Metastasis Rev 1992; 11(1): 5-20.
-
(1992)
Cancer Metastasis Rev
, vol.11
, Issue.1
, pp. 5-20
-
-
Nabi, I.R.1
Watanabe, H.2
Raz, A.3
-
14
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review. Cancer Res 1989; 49: 6449-65.
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
15
-
-
0025334830
-
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy
-
Boucher Y, Baxter LT, Jain RK. Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy. Cancer Res 1990; 50: 4478-84.
-
(1990)
Cancer Res
, vol.50
, pp. 4478-4484
-
-
Boucher, Y.1
Baxter, L.T.2
Jain, R.K.3
-
16
-
-
0016218630
-
Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation
-
Liotta LA, Kleinerman J, Saidel GM. Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res 1974; 34: 997-1004.
-
(1974)
Cancer Res
, vol.34
, pp. 997-1004
-
-
Liotta, L.A.1
Kleinerman, J.2
Saidel, G.M.3
-
17
-
-
0034829350
-
Mouse models of metastatic pancreatic adenocarcinoma
-
Xie K, Wang B, Shi Q et al. Mouse models of metastatic pancreatic adenocarcinoma. Intl J Pancreatol 2001; 29: 21-7.
-
(2001)
Intl J Pancreatol
, vol.29
, pp. 21-27
-
-
Xie, K.1
Wang, B.2
Shi, Q.3
-
18
-
-
0034243929
-
Experimental animal models for pancreatic cancer
-
Shi Q, Xie K. Experimental animal models for pancreatic cancer. Int J Oncol 2000; 17: 217-25.
-
(2000)
Int J Oncol
, vol.17
, pp. 217-225
-
-
Shi, Q.1
Xie, K.2
-
19
-
-
0014865396
-
125I-5-iodo-2′-deoxyuridine
-
125I-5-iodo-2′-deoxyuridine. J Natl Cancer Inst 1970; 45: 773-82.
-
(1970)
J Natl Cancer Inst
, vol.45
, pp. 773-782
-
-
Fidler, I.J.1
-
20
-
-
0022547699
-
Intravascular death of disseminated cancer cells mediated by superoxide anion
-
Glaves D. Intravascular death of disseminated cancer cells mediated by superoxide anion. Invasion Metastasis 1986; 6: 101-11.
-
(1986)
Invasion Metastasis
, vol.6
, pp. 101-111
-
-
Glaves, D.1
-
21
-
-
0033756843
-
A model of spontaneous lung metastases visualised in fresh host tissue by green fluorescent protein expression
-
Paris S, Chauzy C, Martin-Vandelet N et al. A model of spontaneous lung metastases visualised in fresh host tissue by green fluorescent protein expression. Clin Exp Metastasis 1999; 17: 817-22.
-
(1999)
Clin Exp Metastasis
, vol.17
, pp. 817-822
-
-
Paris, S.1
Chauzy, C.2
Martin-Vandelet, N.3
-
22
-
-
0031005838
-
Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression
-
Chishima T, Miyagi Y, Wang X et al. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. Cancer Res 1997; 57: 2042-7.
-
(1997)
Cancer Res
, vol.57
, pp. 2042-2047
-
-
Chishima, T.1
Miyagi, Y.2
Wang, X.3
-
23
-
-
0032799478
-
Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis
-
Naumov GN, Wilson S, MacDonald IC et al. Cellular expression of green fluorescent protein, coupled with high-resolution in vivo videomicroscopy, to monitor steps in tumor metastasis. J Cell Sci 1999; 112: 1835-42.
-
(1999)
J Cell Sci
, vol.112
, pp. 1835-1842
-
-
Naumov, G.N.1
Wilson, S.2
MacDonald, I.C.3
-
24
-
-
0017704436
-
Metastasis results from preexisting variant cells within a malignant tumor
-
Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977; 197: 893-5.
-
(1977)
Science
, vol.197
, pp. 893-895
-
-
Fidler, I.J.1
Kripke, M.L.2
-
25
-
-
0025301851
-
The cellular basis of site-specific tumor metastasis
-
Zetter BR. The cellular basis of site-specific tumor metastasis. N Engl J Med 1990; 322: 605-12.
-
(1990)
N Engl J Med
, vol.322
, pp. 605-612
-
-
Zetter, B.R.1
-
26
-
-
0019939323
-
Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors
-
Talmadge JE, Fidler IJ. Enhanced metastatic potential of tumor cells harvested from spontaneous metastases of heterogeneous murine tumors. J Natl Cancer Inst 1982; 69: 975-80.
-
(1982)
J Natl Cancer Inst
, vol.69
, pp. 975-980
-
-
Talmadge, J.E.1
Fidler, I.J.2
-
27
-
-
0017234894
-
The significance of hematogenous tumor cell clumps in the metastatic process
-
Liotta LA, Kleinerman J, Saidel GM. The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Res 1976; 36: 889-94.
-
(1976)
Cancer Res
, vol.36
, pp. 889-894
-
-
Liotta, L.A.1
Kleinerman, J.2
Saidel, G.M.3
-
28
-
-
0026654619
-
Early steps in hematogenous metastasis of B16F1 melanoma cells in chick embryos studied by high-resolution intravital videomicroscopy
-
Chambers AF, Schmidt EE, MacDonald IC et al. Early steps in hematogenous metastasis of B16F1 melanoma cells in chick embryos studied by high-resolution intravital videomicroscopy. J Natl Cancer Inst 1992; 84: 797-803.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 797-803
-
-
Chambers, A.F.1
Schmidt, E.E.2
MacDonald, I.C.3
-
29
-
-
0031655802
-
Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases
-
Luzzi KJ, MacDonald IC, Schmidt EE et al. Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am J Patrol 1998; 153: 865-73.
-
(1998)
Am J Patrol
, vol.153
, pp. 865-873
-
-
Luzzi, K.J.1
MacDonald, I.C.2
Schmidt, E.E.3
-
30
-
-
0001826912
-
TNF-mediated cytotoxicity in sensitive and resistant L929 fibroblasts correlates with nitric oxide-independent and -dependent mechanisms, respectively
-
Xie K, Fidler IJ. TNF-mediated cytotoxicity in sensitive and resistant L929 fibroblasts correlates with nitric oxide-independent and -dependent mechanisms, respectively. J Leuk Biol (Suppl) 1992; 3: 45.
-
(1992)
J Leuk Biol (Suppl)
, vol.3
, pp. 45
-
-
Xie, K.1
Fidler, I.J.2
-
31
-
-
0027376463
-
Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric oxide
-
Xie K, Huang S, Dong Z et al. Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric oxide. Int J Oncol 1993; 3: 1043-7.
-
(1993)
Int J Oncol
, vol.3
, pp. 1043-1047
-
-
Xie, K.1
Huang, S.2
Dong, Z.3
-
32
-
-
0034037286
-
Microenvironment-induced cancer metastasis
-
Rofstad EK. Microenvironment-induced cancer metastasis. Int J Radiat Biol 2000; 76(5): 589-605.
-
(2000)
Int J Radiat Biol
, vol.76
, Issue.5
, pp. 589-605
-
-
Rofstad, E.K.1
-
33
-
-
0034855105
-
Hypoxia and oxidative stress in breast cancer. Oxidative stress: Its effects on the growth, metastatic potential and response to therapy of breast cancer
-
Brown NS, Bicknell R. Hypoxia and oxidative stress in breast cancer. Oxidative stress: Its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res. 2001; 3(5): 323-7.
-
(2001)
Breast Cancer Res
, vol.3
, Issue.5
, pp. 323-327
-
-
Brown, N.S.1
Bicknell, R.2
-
34
-
-
0033867776
-
Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
-
Dachs GU, Tozer GM. Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer 2000; 36 (13 Spec No): 1649-60.
-
(2000)
Eur J Cancer
, vol.36
, Issue.13 SPEC. NO.
, pp. 1649-1660
-
-
Dachs, G.U.1
Tozer, G.M.2
-
35
-
-
0012281768
-
Gene therapy with the inducible nitric oxide synthase for induction of apoptosis to control tumor growth and metastasis
-
Xie K, Fidler IJ. Gene therapy with the inducible nitric oxide synthase for induction of apoptosis to control tumor growth and metastasis. Cancer Metastasis Rev 1998; 17: 255-75.
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 255-275
-
-
Xie, K.1
Fidler, I.J.2
-
36
-
-
0030049032
-
Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer
-
Wiseman H, Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer. Biochem J 1996; 313 (Pt 1): 17-29.
-
(1996)
Biochem J
, vol.313
, Issue.PART 1
, pp. 17-29
-
-
Wiseman, H.1
Halliwell, B.2
-
37
-
-
0036173591
-
Hypoxia as a target for combined modality treatments
-
Wouters BG, Weppler SA, Koritzinsky M et al. Hypoxia as a target for combined modality treatments. Eur J Cancer 2002; 38(2): 240-57.
-
(2002)
Eur J Cancer
, vol.38
, Issue.2
, pp. 240-257
-
-
Wouters, B.G.1
Weppler, S.A.2
Koritzinsky, M.3
-
38
-
-
0024213268
-
Glucose uptake, lactate release, ketone body turnover, metabolic micromilieu, and pH distributions in human breast cancer xenografts in nude rats
-
Kallinowski F, Vaupel P, Runkel S et al. Glucose uptake, lactate release, ketone body turnover, metabolic micromilieu, and pH distributions in human breast cancer xenografts in nude rats. Cancer Res 1988; (24 Pt 1): 7264-72.
-
(1988)
Cancer Res
, Issue.24 PART 1
, pp. 7264-7272
-
-
Kallinowski, F.1
Vaupel, P.2
Runkel, S.3
-
40
-
-
0020084806
-
Vascularization of tumors: A review
-
Shubik P. Vascularization of tumors: A review. J Cancer Res Clin Oncol 1982; 103(3): 211-26.
-
(1982)
J Cancer Res Clin Oncol
, vol.103
, Issue.3
, pp. 211-226
-
-
Shubik, P.1
-
41
-
-
0023909330
-
Determinants of tumor blood flow: A review
-
Jain RK. Determinants of tumor blood flow: A review. Cancer Res 1988; 48(10): 2641-58.
-
(1988)
Cancer Res
, vol.48
, Issue.10
, pp. 2641-2658
-
-
Jain, R.K.1
-
42
-
-
0023107539
-
Intermittent blood flow in a murine tumor: Radiobiological effects
-
Chaplin DJ, Olive PL, Durand RE. Intermittent blood flow in a murine tumor: Radiobiological effects. Cancer Res 1987; 47(2): 597-601.
-
(1987)
Cancer Res
, vol.47
, Issue.2
, pp. 597-601
-
-
Chaplin, D.J.1
Olive, P.L.2
Durand, R.E.3
-
43
-
-
0021732164
-
The relevance of tumour pH to the treatment of malignant disease
-
Wike-Hooley JL, Haveman J, Reinhold HS. The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 1984; 2(4): 343-66.
-
(1984)
Radiother Oncol
, vol.2
, Issue.4
, pp. 343-366
-
-
Wike-Hooley, J.L.1
Haveman, J.2
Reinhold, H.S.3
-
44
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock IF, Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989; 49(16): 4373-84.
-
(1989)
Cancer Res
, vol.49
, Issue.16
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
45
-
-
0025738682
-
Evaluation of BA1112 rhabdomyosarcoma oxygenation with microelectrodes, optical spectrophotometry, radiosensitivity, and magnetic resonance spectroscopy
-
Sostman HD, Rockwell S, Sylvia AL et al. Evaluation of BA1112 rhabdomyosarcoma oxygenation with microelectrodes, optical spectrophotometry, radiosensitivity, and magnetic resonance spectroscopy. Magn Reson Med 1991; 20(2): 253-67.
-
(1991)
Magn Reson Med
, vol.20
, Issue.2
, pp. 253-267
-
-
Sostman, H.D.1
Rockwell, S.2
Sylvia, A.L.3
-
46
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Höckel M, Vaupel P. Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001; 93: 266-76.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Höckel, M.1
Vaupel, P.2
-
47
-
-
0034176645
-
The antioxidant paradox
-
Halliwell B. The antioxidant paradox. Lancet 2000; 355(9210): 1179-80.
-
(2000)
Lancet
, vol.355
, Issue.9210
, pp. 1179-1180
-
-
Halliwell, B.1
-
48
-
-
0029918901
-
Role of oxygen free radicals in cancer development
-
Dreher D, Junod AF. Role of oxygen free radicals in cancer development. Eur J Cancer 1996; 32A(1): 30-8.
-
(1996)
Eur J Cancer
, vol.32 A
, Issue.1
, pp. 30-38
-
-
Dreher, D.1
Junod, A.F.2
-
49
-
-
0030986262
-
Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
-
Ambs S, Hussain SP, Harris CC. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J 1997; 11(6): 443-8.
-
(1997)
FASEB J
, vol.11
, Issue.6
, pp. 443-448
-
-
Ambs, S.1
Hussain, S.P.2
Harris, C.C.3
-
50
-
-
0026629902
-
Nitric oxide as a secretory product of mammalian cells
-
Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6: 3051-64.
-
(1992)
FASEB J
, vol.6
, pp. 3051-3064
-
-
Nathan, C.1
-
51
-
-
0032957595
-
Nitric oxide: Discovery and impact on clinical medicine
-
Moncada S. Nitric oxide: Discovery and impact on clinical medicine. J R Soc Med 1999; 92: 164-9.
-
(1999)
J R Soc Med
, vol.92
, pp. 164-169
-
-
Moncada, S.1
-
52
-
-
0031845632
-
The multifaceted roles of nitric oxide in cancer
-
Wink DA, Vodovotz Y, Laval J et al. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 1998; 19: 711-21.
-
(1998)
Carcinogenesis
, vol.19
, pp. 711-721
-
-
Wink, D.A.1
Vodovotz, Y.2
Laval, J.3
-
53
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo G, Musso T, Sica A et al. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Expl Med 1995; 182: 1683-93.
-
(1995)
J Expl Med
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
-
54
-
-
0032570596
-
Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation
-
Bellocq A, Suberville S, Philippe C et al. Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation. J Biol Chem 1998; 273: 5086-92.
-
(1998)
J Biol Chem
, vol.273
, pp. 5086-5092
-
-
Bellocq, A.1
Suberville, S.2
Philippe, C.3
-
55
-
-
0034657272
-
Influence of nitric oxide synthase II gene disruption on tumor growth and metastasis
-
Shi Q, Xiong Q, Wang B et al. Influence of nitric oxide synthase II gene disruption on tumor growth and metastasis. Cancer Res 2000; 60: 2579-83.
-
(2000)
Cancer Res
, vol.60
, pp. 2579-2583
-
-
Shi, Q.1
Xiong, Q.2
Wang, B.3
-
56
-
-
0035132925
-
Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma
-
Wang B, Xiong Q, Shi Q et al. Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma. Cancer Res 2001; 61: 71-5.
-
(2001)
Cancer Res
, vol.61
, pp. 71-75
-
-
Wang, B.1
Xiong, Q.2
Shi, Q.3
-
57
-
-
0035909513
-
Genetic disruption of host interferon-gamma drastically enhances the metastasis of pancreatic adenocarcinoma through impaired expression of inducible nitric oxide synthase
-
Wang B, Xiong Q, Shi Q et al. Genetic disruption of host interferon-gamma drastically enhances the metastasis of pancreatic adenocarcinoma through impaired expression of inducible nitric oxide synthase. Oncogene 2001; 20: 6930-7.
-
(2001)
Oncogene
, vol.20
, pp. 6930-6937
-
-
Wang, B.1
Xiong, Q.2
Shi, Q.3
-
58
-
-
0035284055
-
Genetic disruption of host nitric oxide synthase II gene impairs melanoma-induced angiogenesis and suppresses pleural effusion
-
Wang B, Xiong Q, Shi Q et al. Genetic disruption of host nitric oxide synthase II gene impairs melanoma-induced angiogenesis and suppresses pleural effusion. Int J Cancer 2001; 91: 607-11.
-
(2001)
Int J Cancer
, vol.91
, pp. 607-611
-
-
Wang, B.1
Xiong, Q.2
Shi, Q.3
-
59
-
-
0030864875
-
Nitric oxide-mediated apoptosis of K-1735 murine melanma cells is associated with down-regulation of Bcl-2
-
Xie K, Wang Y, Huang S et al. Nitric oxide-mediated apoptosis of K-1735 murine melanma cells is associated with down-regulation of Bcl-2. Oncogene 1997; 15: 771-9.
-
(1997)
Oncogene
, vol.15
, pp. 771-779
-
-
Xie, K.1
Wang, Y.2
Huang, S.3
-
60
-
-
0033135593
-
Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53
-
Shi Q, Huang S, Jiang W et al. Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53. Cancer Res 1999; 59: 2072-5.
-
(1999)
Cancer Res
, vol.59
, pp. 2072-2075
-
-
Shi, Q.1
Huang, S.2
Jiang, W.3
-
61
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Höckel M, Schlenger K, Arai B et al. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996; 56: 4509-15.
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Höckel, M.1
Schlenger, K.2
Arai, B.3
-
62
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel DM, Scully SP, Harrelson JM et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 1996; 56: 941-3.
-
(1996)
Cancer Res
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
63
-
-
0033922706
-
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
-
Rofstad EK, Sundfør K, Lyng H, Tropé CG. Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br J Cancer 2000; 83: 354-9.
-
(2000)
Br J Cancer
, vol.83
, pp. 354-359
-
-
Rofstad, E.K.1
Sundfør, K.2
Lyng, H.3
Tropé, C.G.4
-
64
-
-
0010170555
-
Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
-
Young SD, Marshall RS, Hill RP. Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc Natl Acad Sci USA 1988; 85: 9533-7.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9533-9537
-
-
Young, S.D.1
Marshall, R.S.2
Hill, R.P.3
-
65
-
-
0030873998
-
An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells
-
Jang A, Hill RP. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells. Clin Exp Metastasis 1997; 15: 469-83.
-
(1997)
Clin Exp Metastasis
, vol.15
, pp. 469-483
-
-
Jang, A.1
Hill, R.P.2
-
66
-
-
0032774194
-
Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis
-
Rofstad EK, Danielsen T. Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis. Br J Cancer 1999; 80: 1697-07.
-
(1999)
Br J Cancer
, vol.80
, pp. 1697-1707
-
-
Rofstad, E.K.1
Danielsen, T.2
-
67
-
-
0035805046
-
Relationship of hypoxia to metastatic ability in rodent tumours
-
De Jaeger K, Kavanagh M-C, Hill RP. Relationship of hypoxia to metastatic ability in rodent tumours. Br J Cancer 2001; 84: 1280-5.
-
(2001)
Br J Cancer
, vol.84
, pp. 1280-1285
-
-
De Jaeger, K.1
Kavanagh, M.-C.2
Hill, R.P.3
-
68
-
-
0031774283
-
Heterogeneity of tumor oxygenation: Relationship to tumor necrosis, tumor size, and metastasis
-
De Jaeger K, Merlo FM, Kavanagh M-C et al. Heterogeneity of tumor oxygenation: Relationship to tumor necrosis, tumor size, and metastasis. Int J Radiat Oncol Biol Phys 1998; 42: 717-1.
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 717-721
-
-
De Jaeger, K.1
Merlo, F.M.2
Kavanagh, M.-C.3
-
69
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Hockel M, Vaupel P. Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001; 93(4): 266-76.
-
(2001)
J Natl Cancer Inst
, vol.93
, Issue.4
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
70
-
-
0029753768
-
Genetic instability induced by the tumor microenvironment
-
Reynolds TY, Rockwell S, Glazer PM. Genetic instability induced by the tumor microenvironment. Cancer Res 1996; 56(24): 5754-7.
-
(1996)
Cancer Res
, vol.56
, Issue.24
, pp. 5754-5757
-
-
Reynolds, T.Y.1
Rockwell, S.2
Glazer, P.M.3
-
71
-
-
0028123571
-
The propensity for gene amplification: A comparison of protocols, cell lines, and selection agents
-
Sharma RC, Schimke RT. The propensity for gene amplification: A comparison of protocols, cell lines, and selection agents. Mutat Res 1994; 304(2): 243-60.
-
(1994)
Mutat Res
, vol.304
, Issue.2
, pp. 243-260
-
-
Sharma, R.C.1
Schimke, R.T.2
-
72
-
-
0028931542
-
An anoxia inducible endonuclease and enhanced DNA breakage as contributors to genomic instability in cancer
-
Russo CA, Weber TK, Volpe CM et al. An anoxia inducible endonuclease and enhanced DNA breakage as contributors to genomic instability in cancer. Cancer Res 1995; 55(5): 1122-8.
-
(1995)
Cancer Res
, vol.55
, Issue.5
, pp. 1122-1128
-
-
Russo, C.A.1
Weber, T.K.2
Volpe, C.M.3
-
73
-
-
0027661830
-
Cell and tissue responses to oxidative damage
-
Janssen YM, Van Houten B, Borm PJ et al. Cell and tissue responses to oxidative damage. Lab Invest 1993; 69(3): 261-74.
-
(1993)
Lab Invest
, vol.69
, Issue.3
, pp. 261-274
-
-
Janssen, Y.M.1
Van Houten, B.2
Borm, P.J.3
-
74
-
-
0242672936
-
Molecular dissection of mammalian gene amplification: New mechanistic insights revealed by analyses of very early events
-
Windle BE, Wahl GM. Molecular dissection of mammalian gene amplification: New mechanistic insights revealed by analyses of very early events. Mutat Res 1992; 276(3): 199-224.
-
(1992)
Mutat Res
, vol.276
, Issue.3
, pp. 199-224
-
-
Windle, B.E.1
Wahl, G.M.2
-
75
-
-
0023621716
-
Amplification of genes in somatic mammalian cells
-
Schimke RT, Roos DS, Brown PC. Amplification of genes in somatic mammalian cells. Methods Enzymol 1987; 151: 85-104.
-
(1987)
Methods Enzymol
, vol.151
, pp. 85-104
-
-
Schimke, R.T.1
Roos, D.S.2
Brown, P.C.3
-
76
-
-
0026018901
-
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration
-
Windle B, Draper BW, Yin YX et al. A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes Dev 1991; 5(2): 160-74.
-
(1991)
Genes Dev
, vol.5
, Issue.2
, pp. 160-174
-
-
Windle, B.1
Draper, B.W.2
Yin, Y.X.3
-
77
-
-
0030986262
-
Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
-
Ambs S, Hussain SP, Harris CC. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J 1997; 11 (6): 443-8.
-
(1997)
FASEB J
, vol.11
, Issue.6
, pp. 443-448
-
-
Ambs, S.1
Hussain, S.P.2
Harris, C.C.3
-
78
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996; 379: 88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
79
-
-
0034978384
-
Estimating the selective advantage of mutant p53 tumour cells to repeated rounds of hypoxia
-
Gammack H, Byrne M, Lewis CE. Estimating the selective advantage of mutant p53 tumour cells to repeated rounds of hypoxia. Bull Math Biol 2001; 63: 135-66.
-
(2001)
Bull Math Biol
, vol.63
, pp. 135-166
-
-
Gammack, H.1
Byrne, M.2
Lewis, C.E.3
-
80
-
-
0030864485
-
Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
-
Kim DCY, Tsai MH, Osmanian C et al. Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. Cancer Res 1997; 57: 4200-4.
-
(1997)
Cancer Res
, vol.57
, pp. 4200-4204
-
-
Kim, D.C.Y.1
Tsai, M.H.2
Osmanian, C.3
-
81
-
-
0031838786
-
Response of tumour cells to hypoxia: Role of p53 and NF-κB
-
Royds JA, Dower SK, Qwarnstrom EE et al. Response of tumour cells to hypoxia: Role of p53 and NF-κB. Mol Pathol 1998; 51: 55-61.
-
(1998)
Mol Pathol
, vol.51
, pp. 55-61
-
-
Royds, J.A.1
Dower, S.K.2
Qwarnstrom, E.E.3
-
82
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
Zundel W, Schindler C, Haas-Kogan D et al. Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev 2000; 14: 391-45.
-
(2000)
Genes Dev
, vol.14
, pp. 391-445
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
-
83
-
-
0033609365
-
An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis
-
Williams AC, Collard TJ, Paraskeva C. An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis. Oncogene 1999; 18(21): 3199-204.
-
(1999)
Oncogene
, vol.18
, Issue.21
, pp. 3199-3204
-
-
Williams, A.C.1
Collard, T.J.2
Paraskeva, C.3
-
84
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-5.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
-
85
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA et al. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510-4.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
-
86
-
-
0025050735
-
Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells
-
Kourembanas S, Hannan RL, Faller DV. Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells. J Clin Invest 1990; 86: 670-4.
-
(1990)
J Clin Invest
, vol.86
, pp. 670-674
-
-
Kourembanas, S.1
Hannan, R.L.2
Faller, D.V.3
-
87
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
-
McQuillan LP, Leung GK, Marsden PA et al. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am J Physiol 1994; 267: H1921-7.
-
(1994)
Am J Physiol
, vol.267
-
-
McQuillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
-
88
-
-
0242408897
-
The regulated expression of erythropoietin by two human hepatoma cell lines
-
Goldberg MA, Glass GA, Cunningham JM et al. The regulated expression of erythropoietin by two human hepatoma cell lines. Proc Natl Acad Sci USA 1987; 84: 7972-6.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7972-7976
-
-
Goldberg, M.A.1
Glass, G.A.2
Cunningham, J.M.3
-
89
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
-
Firth JD, Ebert BL, Pugh CW et al. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer. Proc Natl Acad Sci USA 1994; 91: 6496-500.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
-
90
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, Roth PH, Fang HM et al. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 1994; 269: 23757-63.
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
-
91
-
-
0026756726
-
Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia
-
Sivitz WI, Lund DD, Yorek B et al. Grover-McKay M, Schmid PG. Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia. Am J Physiol 1992; 263: E562-9.
-
(1992)
Am J Physiol
, vol.263
-
-
Sivitz, W.I.1
Lund, D.D.2
Yorek, B.3
Grover-McKay, M.4
Schmid, P.G.5
-
92
-
-
0030045543
-
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: Similarities with the regulation of erythropoietin
-
Ebert BL, Gleadle JM, O'Rourke JF et al. Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: Similarities with the regulation of erythropoietin. Biochem J 1996; 313: 809-14.
-
(1996)
Biochem J
, vol.313
, pp. 809-814
-
-
Ebert, B.L.1
Gleadle, J.M.2
O'Rourke, J.F.3
-
93
-
-
0028129435
-
Regulation of c-jun expression during hypoxic and low-glucose stress
-
Ausserer WA, Bourrat-Floeck B, Green CJ et al. Regulation of c-jun expression during hypoxic and low-glucose stress. Mol Cell Biol 1994; 14: 5032-42.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5032-5042
-
-
Ausserer, W.A.1
Bourrat-Floeck, B.2
Green, C.J.3
-
94
-
-
0026000979
-
Rabbit aortic endothelial cell hypoxia induces secretion of transforming growth factor beta and augments macrophage adhesion in vitro
-
Santilli SM, Fiegel VD, Aldridge DE et al. Rabbit aortic endothelial cell hypoxia induces secretion of transforming growth factor beta and augments macrophage adhesion in vitro. Ann Vasc Surg 1991; 5: 429-38.
-
(1991)
Ann Vasc Surg
, vol.5
, pp. 429-438
-
-
Santilli, S.M.1
Fiegel, V.D.2
Aldridge, D.E.3
-
95
-
-
0028843411
-
Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents
-
Gleadle JM, Ebert BL, Firth JD et al. Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am J Physiol 1995; 268: C1362-8.
-
(1995)
Am J Physiol
, vol.268
-
-
Gleadle, J.M.1
Ebert, B.L.2
Firth, J.D.3
-
96
-
-
0032079312
-
Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway
-
Graham CH, Fitzpatrick TE, McCrae KR. Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway. Blood 1998; 91: 3300-7.
-
(1998)
Blood
, vol.91
, pp. 3300-3307
-
-
Graham, C.H.1
Fitzpatrick, T.E.2
McCrae, K.R.3
-
97
-
-
0032528997
-
Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression
-
Mishra RR, Adhikary G, Simonson MS et al. Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression. Brain Res Mol Brain Res 1998; 59(1): 74-83.
-
(1998)
Brain Res Mol Brain Res
, vol.59
, Issue.1
, pp. 74-83
-
-
Mishra, R.R.1
Adhikary, G.2
Simonson, M.S.3
-
98
-
-
0032487925
-
Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities
-
Krtolica A, Krucher NA, Ludlow JW. Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities. Oncogene 1998; 17: 2295-304.
-
(1998)
Oncogene
, vol.17
, pp. 2295-2304
-
-
Krtolica, A.1
Krucher, N.A.2
Ludlow, J.W.3
-
99
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P, Dor Y, Herbert JM et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998; 394: 485-90.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
-
100
-
-
0033521864
-
Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression
-
Graham CH, Forsdike J, Fitzgerald CJ et al. Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression. Int J Cancer 1999; 80(4): 617-23.
-
(1999)
Int J Cancer
, vol.80
, Issue.4
, pp. 617-623
-
-
Graham, C.H.1
Forsdike, J.2
Fitzgerald, C.J.3
-
101
-
-
0026758210
-
Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen
-
Laderoute KR, Grant TD, Murphy BJ et al. Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen. Int J Cancer 1992; 52(3): 428-32.
-
(1992)
Int J Cancer
, vol.52
, Issue.3
, pp. 428-432
-
-
Laderoute, K.R.1
Grant, T.D.2
Murphy, B.J.3
-
102
-
-
0032570760
-
Studies of type IV collagenase regulation by hypoxia
-
Himelstein BP, Koch CJ. Studies of type IV collagenase regulation by hypoxia. Cancer Lett 1998, 124(2): 127-33.
-
(1998)
Cancer Lett
, vol.124
, Issue.2
, pp. 127-133
-
-
Himelstein, B.P.1
Koch, C.J.2
-
103
-
-
0032712997
-
Constitutive and inducible interleukin-8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic
-
Shi Q, Abbruzzese JL, Huang S et al. Constitutive and inducible interleukin-8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin. Cancer Res 1999; 5: 3711-21.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3711-3721
-
-
Shi, Q.1
Abbruzzese, J.L.2
Huang, S.3
-
104
-
-
0033403652
-
Cooperation between transcription factor AP-4 and NF-κB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia
-
Shi Q, Le X, Abbruzzese JL et al. Cooperation between transcription factor AP-4 and NF-κB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia. J Interferon Cytokine Res 1999; 19: 1363-1.
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 1363-1371
-
-
Shi, Q.1
Le, X.2
Abbruzzese, J.L.3
-
105
-
-
0034849755
-
Interleukin-8 and human cancer biology
-
Xie K. Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 2001; 12: 375-91.
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 375-391
-
-
Xie, K.1
-
106
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992; 12: 5447-4.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
107
-
-
0028110809
-
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
-
Graeber TG, Peterson JF, Tsai M et al. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol 1994; 14: 6264-77.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
-
108
-
-
15144350613
-
Nuclear factor interleukin 6 motifs mediate tissue-specific gene transcription in hypoxia
-
Yah SF, Zou YS, Mendelsohn M et al. Nuclear factor interleukin 6 motifs mediate tissue-specific gene transcription in hypoxia. J Biol Chem 1997; 272: 4287-94.
-
(1997)
J Biol Chem
, vol.272
, pp. 4287-4294
-
-
Yah, S.F.1
Zou, Y.S.2
Mendelsohn, M.3
-
109
-
-
0027936404
-
Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia
-
Yao KS, Xanthoudakis S, Curran T et al. Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Mol Cell Biol 1994; 14: 5997-6003.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5997-6003
-
-
Yao, K.S.1
Xanthoudakis, S.2
Curran, T.3
-
110
-
-
0033591346
-
Hypoxia-associated induction of early growth response-1 gene expression
-
Yan SF, Lu J, Zou YS et al. Hypoxia-associated induction of early growth response-1 gene expression. J Biol Chem 1999; 274: 15030-40.
-
(1999)
J Biol Chem
, vol.274
, pp. 15030-15040
-
-
Yan, S.F.1
Lu, J.2
Zou, Y.S.3
-
111
-
-
0028268629
-
Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues
-
Koong AC, Chen EY, Giaccia AJ. Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. Cancer Res 1994; 54: 1425-30.
-
(1994)
Cancer Res
, vol.54
, pp. 1425-1430
-
-
Koong, A.C.1
Chen, E.Y.2
Giaccia, A.J.3
-
112
-
-
0035029319
-
Hypoxia-inducible factor 1: Control of oxygen homeostasis in health and disease
-
Semenza L. Hypoxia-inducible factor 1: Control of oxygen homeostasis in health and disease. Pediatr Res 2001; 49: 614-7.
-
(2001)
Pediatr Res
, vol.49
, pp. 614-617
-
-
Semenza, L.1
-
113
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992; 12: 5447-54.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
114
-
-
0027230099
-
A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer
-
Madan A, Curtin PT. A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer. Proc Natl Acad Sci USA 1993; 90: 3928-32.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3928-3932
-
-
Madan, A.1
Curtin, P.T.2
-
115
-
-
0028105848
-
Hypoxia regulatory elements of the human vascular endothelial growth factor gene
-
Minchenko A, Salceda S, Bauer T et al. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell Mol Biol Res 1994; 40: 35-9.
-
(1994)
Cell Mol Biol Res
, vol.40
, pp. 35-39
-
-
Minchenko, A.1
Salceda, S.2
Bauer, T.3
-
116
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo G, Musso T, Sica A et al.A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 1995; 182: 1683-93.
-
(1995)
J Exp Med
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
-
117
-
-
0030751493
-
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
-
Gerber HP, Condorelli F, Park J et al. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem 1997; 272: 23659-67.
-
(1997)
J Biol Chem
, vol.272
, pp. 23659-23667
-
-
Gerber, H.P.1
Condorelli, F.2
Park, J.3
-
118
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer NV, Kotch LE, Agani F et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998; 12: 149-62.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
-
119
-
-
0031974197
-
Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma
-
Kim KW, Bae SK, Lee OH et al. Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res 1998; 58(2): 348-51.
-
(1998)
Cancer Res
, vol.58
, Issue.2
, pp. 348-351
-
-
Kim, K.W.1
Bae, S.K.2
Lee, O.H.3
-
120
-
-
0027172514
-
Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells
-
Beck I, Weinmann R, Caro J. Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells. Blood 1993; 82: 704-11.
-
(1993)
Blood
, vol.82
, pp. 704-711
-
-
Beck, I.1
Weinmann, R.2
Caro, J.3
-
121
-
-
0027427588
-
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
-
Wang GL, Semenza GL. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem 1993; 268: 21513-8.
-
(1993)
J Biol Chem
, vol.268
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
122
-
-
0031835957
-
Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein
-
Ebert BL, Bunn HF. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein. Mol Cell Biol 1998; 18: 4089-96.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4089-4096
-
-
Ebert, B.L.1
Bunn, H.F.2
-
123
-
-
0030961006
-
Hypoxia-inducible factor lalpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda S, Caro J. Hypoxia-inducible factor lalpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 1997; 272: 22642-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
124
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza GL. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 2000; 35(2): 71-103.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, Issue.2
, pp. 71-103
-
-
Semenza, G.L.1
-
125
-
-
0030873998
-
An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells
-
Jang A, Hill RP. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells. Clin Exp Metastasis 1997; 15(5): 469-83.
-
(1997)
Clin Exp Metastasis
, vol.15
, Issue.5
, pp. 469-483
-
-
Jang, A.1
Hill, R.P.2
-
126
-
-
0021075626
-
The effects of glucose on protein synthesis and thermosensitivity in Chinese hamster ovary cells
-
Sciandra JJ, Subjeck JR. The effects of glucose on protein synthesis and thermosensitivity in Chinese hamster ovary cells. J Biol Chem 1983; 258(20): 12091-3.
-
(1983)
J Biol Chem
, vol.258
, Issue.20
, pp. 12091-12093
-
-
Sciandra, J.J.1
Subjeck, J.R.2
-
127
-
-
0017665008
-
Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation
-
Pouyssegur J, Shiu RP, Pastan I. Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation. Cell 1977; 11(4): 941-7.
-
(1977)
Cell
, vol.11
, Issue.4
, pp. 941-947
-
-
Pouyssegur, J.1
Shiu, R.P.2
Pastan, I.3
-
128
-
-
0025300038
-
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation
-
Mosser DD, Kotzbauer PT, Sarge KD et al. In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation. Proc Natl Acad Sci USA 1990; 87(10): 3748-52.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.10
, pp. 3748-3752
-
-
Mosser, D.D.1
Kotzbauer, P.T.2
Sarge, K.D.3
-
129
-
-
0022352547
-
Differential induction of glucose-regulated and heat shock proteins: Effects of pH and sulfhydryl-reducing agents on chicken embryo cells
-
Whelan SA, Hightower LE. Differential induction of glucose-regulated and heat shock proteins: Effects of pH and sulfhydryl-reducing agents on chicken embryo cells. J Cell Physiol 1985; 125(2): 251-8.
-
(1985)
J Cell Physiol
, vol.125
, Issue.2
, pp. 251-258
-
-
Whelan, S.A.1
Hightower, L.E.2
-
130
-
-
0032473399
-
Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines
-
Scott PA, Gleadle JM, Bicknell R et al. Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines. Int J Cancer 1998; 75(5): 706-12.
-
(1998)
Int J Cancer
, vol.75
, Issue.5
, pp. 706-712
-
-
Scott, P.A.1
Gleadle, J.M.2
Bicknell, R.3
-
131
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
-
Shweiki D, Neeman M, Itin A et al. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc Natl Acad Sci USA 1995; 92(3): 768-72.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.3
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
-
132
-
-
0029982979
-
Acidic pH enhances the invasive behavior of human melanoma cells
-
Martinez-Zaguilan R, Seftor EA, Seftor RE et al. Acidic pH enhances the invasive behavior of human melanoma cells. Clin Exp Metastasis 1996; 14(2): 176-86.
-
(1996)
Clin Exp Metastasis
, vol.14
, Issue.2
, pp. 176-186
-
-
Martinez-Zaguilan, R.1
Seftor, E.A.2
Seftor, R.E.3
-
133
-
-
0026667311
-
Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines
-
Kato Y, Nakayama Y, Umeda M et al. Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines. J Biol Chem 1992; 267(16): 11424-30.
-
(1992)
J Biol Chem
, vol.267
, Issue.16
, pp. 11424-11430
-
-
Kato, Y.1
Nakayama, Y.2
Umeda, M.3
-
134
-
-
0025918734
-
The malignant phenotype and cysteine proteinases
-
Sloane BF, Rozhin J, Krepela E et al. The malignant phenotype and cysteine proteinases. Biomed Biochim Acta 1991; 50(4-6): 549-54.
-
(1991)
Biomed Biochim Acta
, vol.50
, Issue.4-6
, pp. 549-554
-
-
Sloane, B.F.1
Rozhin, J.2
Krepela, E.3
-
135
-
-
0029133608
-
The acid deoxyribonuclease of neutrophils: A possible participant in apoptosis-associated genome destruction
-
Gottlieb RA, Giesing HA, Engler RL et al. The acid deoxyribonuclease of neutrophils: A possible participant in apoptosis-associated genome destruction. Blood 1995; 86(6): 2414-8.
-
(1995)
Blood
, vol.86
, Issue.6
, pp. 2414-2418
-
-
Gottlieb, R.A.1
Giesing, H.A.2
Engler, R.L.3
-
136
-
-
0029897419
-
The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosis
-
Morana SJ, Wolf CM, Li J et al. The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosis. J Biol Chem 1996; 271(30): 18263-71.
-
(1996)
J Biol Chem
, vol.271
, Issue.30
, pp. 18263-18271
-
-
Morana, S.J.1
Wolf, C.M.2
Li, J.3
-
137
-
-
0029791228
-
An apoptotic endonuclease activated either by decreasing pH or by increasing calcium
-
Collins MK, Furlong IJ, Malde P et al. An apoptotic endonuclease activated either by decreasing pH or by increasing calcium. J Cell Sci 1996; 109 (Pt 9): 2393-9.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 9
, pp. 2393-2399
-
-
Collins, M.K.1
Furlong, I.J.2
Malde, P.3
-
138
-
-
0025771024
-
Glucose starvation and acidosis: Effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells
-
Schlappack OK, Zimmermann A, Hill RP. Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer 1991; 64(4): 663-70.
-
(1991)
Br J Cancer
, vol.64
, Issue.4
, pp. 663-670
-
-
Schlappack, O.K.1
Zimmermann, A.2
Hill, R.P.3
-
139
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin J, Sameni M, Ziegler G et al. Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res 1994; 54(24): 6517-25.
-
(1994)
Cancer Res
, vol.54
, Issue.24
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
-
140
-
-
0018590846
-
Increased release of tumour cells by collagenase at acid pH: A possible mechanism for metastasis
-
Turner GA. Increased release of tumour cells by collagenase at acid pH: A possible mechanism for metastasis. Experientia 1979; 35(12): 1657-8.
-
(1979)
Experientia
, vol.35
, Issue.12
, pp. 1657-1658
-
-
Turner, G.A.1
-
141
-
-
0022547236
-
The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease
-
Morisset M, Capony F, Rochefort H. The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease. Biochem Biophys Res Commun 1986; 138(1): 102-9.
-
(1986)
Biochem Biophys Res Commun
, vol.138
, Issue.1
, pp. 102-109
-
-
Morisset, M.1
Capony, F.2
Rochefort, H.3
-
142
-
-
0029840367
-
Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D
-
van der Stappen JW, Williams AC, Maciewicz RA et al. Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D. Int J Cancer 1996; 67(4): 547-54.
-
(1996)
Int J Cancer
, vol.67
, Issue.4
, pp. 547-554
-
-
Van Der Stappen, J.W.1
Williams, A.C.2
Maciewicz, R.A.3
-
144
-
-
0025844721
-
Biological response of multicellular EMT6 spheroids to exogenous lactate
-
Bourrat-Floeck B, Groebe K, Mueller-Klieser W. Biological response of multicellular EMT6 spheroids to exogenous lactate. Int J Cancer 1991; 47(5): 792-9.
-
(1991)
Int J Cancer
, vol.47
, Issue.5
, pp. 792-799
-
-
Bourrat-Floeck, B.1
Groebe, K.2
Mueller-Klieser, W.3
-
145
-
-
0035927544
-
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells
-
Shi Q, Le X, Wang B et al. Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. Oncogene 2001; 20: 3751-6.
-
(2001)
Oncogene
, vol.20
, pp. 3751-3756
-
-
Shi, Q.1
Le, X.2
Wang, B.3
-
146
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996; 379: 88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
147
-
-
0030864485
-
Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
-
Kim CY, Tsai MH, Osmanian C et al. Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. Cancer Res 1997: 57(19): 4200-4.
-
(1997)
Cancer Res
, vol.57
, Issue.19
, pp. 4200-4204
-
-
Kim, C.Y.1
Tsai, M.H.2
Osmanian, C.3
-
148
-
-
0029126765
-
Inhibition of angiogenesis, tumor growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate
-
Pipili-Synetos E, Papageorgiou A, Sakkoula E et al. Inhibition of angiogenesis, tumor growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. Br J Pharmacol 1995; 116: 1829-4.
-
(1995)
Br J Pharmacol
, vol.116
, pp. 1829-1834
-
-
Pipili-Synetos, E.1
Papageorgiou, A.2
Sakkoula, E.3
-
149
-
-
0028170997
-
Effects of NG-nitro-L-arginine and/or L-arginine on experimental pulmonary metastasis in mice
-
Yamamoto T, Terada N, Nishizawa Y et al. Effects of NG-nitro-L-arginine and/or L-arginine on experimental pulmonary metastasis in mice. Cancer Lett 1994; 87: 115-20.
-
(1994)
Cancer Lett
, vol.87
, pp. 115-120
-
-
Yamamoto, T.1
Terada, N.2
Nishizawa, Y.3
-
150
-
-
0032484562
-
Increase in experimental pulmonary metastasis in mice by L-arginine under inhibition of nitric oxide production by NG-nitro-L-arginine methyl ester
-
Yamamoto T, Terada N, Seiyama A et al. Increase in experimental pulmonary metastasis in mice by L-arginine under inhibition of nitric oxide production by NG-nitro-L-arginine methyl ester. Int J Cancer 1998; 75: 140-4.
-
(1998)
Int J Cancer
, vol.75
, pp. 140-144
-
-
Yamamoto, T.1
Terada, N.2
Seiyama, A.3
-
151
-
-
0030613746
-
NG-nitro-L-arginine methyl ester inhibits bone metastasis after modified intracardiac injection of human breast cancer cells in a nude mouse model
-
Iwasaki T, Higashiyama M, Kuriyama K et al. NG-nitro-L-arginine methyl ester inhibits bone metastasis after modified intracardiac injection of human breast cancer cells in a nude mouse model. Jpn J Cancer Res 1997; 88: 861-6.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 861-866
-
-
Iwasaki, T.1
Higashiyama, M.2
Kuriyama, K.3
-
152
-
-
0026069593
-
Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells
-
Li L, Nicolson GL, Fidler IJ. Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells. Cancer Res 1991; 51: 245-54.
-
(1991)
Cancer Res
, vol.51
, pp. 245-254
-
-
Li, L.1
Nicolson, G.L.2
Fidler, I.J.3
-
153
-
-
0022357902
-
Macrophages and metastasis - A biological approach to cancer therapy: Presidential address
-
Fidler IJ. Macrophages and metastasis - a biological approach to cancer therapy: Presidential address. Cancer Res 1985; 45: 4714-21.
-
(1985)
Cancer Res
, vol.45
, pp. 4714-4721
-
-
Fidler, I.J.1
-
154
-
-
0028856579
-
Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo
-
Rocha M, Kruger A, Van Rooijen N et al. Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo. Intl J Cancer 1995; 63: 405-11.
-
(1995)
Intl J Cancer
, vol.63
, pp. 405-411
-
-
Rocha, M.1
Kruger, A.2
Van Rooijen, N.3
-
155
-
-
0032054970
-
Role of nitric oxide and superoxide anion in elimination of low metastatic human colorectal carcinomas by unstimulated hepatic sinusoidal endothelial cells
-
Edmiston KH, Shoji Y, Mizoi T et al. Role of nitric oxide and superoxide anion in elimination of low metastatic human colorectal carcinomas by unstimulated hepatic sinusoidal endothelial cells. Cancer Res 1998; 58: 1524-31.
-
(1998)
Cancer Res
, vol.58
, pp. 1524-1531
-
-
Edmiston, K.H.1
Shoji, Y.2
Mizoi, T.3
-
156
-
-
0034667417
-
B16 melanoma cell arrest in the mouse liver induces nitric oxide release and sinusoidal cytotoxicity: A natural hepatic defense against metastasis
-
Wang HH, McIntosh AR, Hasinoff BB et al. B16 melanoma cell arrest in the mouse liver induces nitric oxide release and sinusoidal cytotoxicity: A natural hepatic defense against metastasis. Cancer Res 2000; 60: 5862-9.
-
(2000)
Cancer Res
, vol.60
, pp. 5862-5869
-
-
Wang, H.H.1
McIntosh, A.R.2
Hasinoff, B.B.3
-
157
-
-
0023092102
-
Macrophage cytotoxicity: Role for L-arginine deiminase activity and amino nitrogen to nitrate
-
Hibbs JR, Taintor JB, Vavrin RR. Macrophage cytotoxicity: Role for L-arginine deiminase activity and amino nitrogen to nitrate. Science 1987; 235: 473-6.
-
(1987)
Science
, vol.235
, pp. 473-476
-
-
Hibbs, J.R.1
Taintor, J.B.2
Vavrin, R.R.3
-
158
-
-
0027325770
-
Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccride-responsive and lipopolysaccride-nonresponsive murine macrophages
-
Dong Z, Qi X, Xie K et al. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccride-responsive and lipopolysaccride-nonresponsive murine macrophages. J Immunol 1993; 151: 2717-4.
-
(1993)
J Immunol
, vol.151
, pp. 2717-2724
-
-
Dong, Z.1
Qi, X.2
Xie, K.3
-
159
-
-
0029594582
-
Activation of inducible nitric oxide synthase in the murine macrophages by interferon-gamma and lipopolysacchride required protein phosphatase I and protein phosphatase 2A activities
-
Dong Z, Yang X, Xie K et al. Activation of inducible nitric oxide synthase in the murine macrophages by interferon-gamma and lipopolysacchride required protein phosphatase I and protein phosphatase 2A activities. J Leuk Biol 1995; 58: 725-32.
-
(1995)
J Leuk Biol
, vol.58
, pp. 725-732
-
-
Dong, Z.1
Yang, X.2
Xie, K.3
-
160
-
-
0034959722
-
Nitric oxide-induced apoptosis in tumor cells
-
200
-
Umansky V, Schirrmacher V. Nitric oxide-induced apoptosis in tumor cells. Adv Cancer Res 200; 82: 107-31.
-
Adv Cancer Res
, vol.82
, pp. 107-131
-
-
Umansky, V.1
Schirrmacher, V.2
-
161
-
-
0027982326
-
Nitric oxide is an important mediator for tumoricidal activity in vivo
-
Farias-Eisner R, Sherman MP, Aeberhard E et al. Nitric oxide is an important mediator for tumoricidal activity in vivo. Proc Natl Acad Sci USA 1994; 91: 9407-11.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9407-9411
-
-
Farias-Eisner, R.1
Sherman, M.P.2
Aeberhard, E.3
-
162
-
-
0029016170
-
Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362
-
Xie K, Huang S, Dons Z et al. Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362. Cancer Res 1995; 55: 3123-31.
-
(1995)
Cancer Res
, vol.55
, pp. 3123-3131
-
-
Xie, K.1
Huang, S.2
Dons, Z.3
-
163
-
-
0026336186
-
Human colorectal adenocarcinoma cells: Differential nitric oxide synthesis determines their ability to aggregate platelets
-
Radomski MK, Jenkins DC, Holmes L et al. Human colorectal adenocarcinoma cells: Differential nitric oxide synthesis determines their ability to aggregate platelets. Cancer Res 1991; 51: 6073-7.
-
(1991)
Cancer Res
, vol.51
, pp. 6073-6077
-
-
Radomski, M.K.1
Jenkins, D.C.2
Holmes, L.3
-
164
-
-
0027958098
-
Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells
-
Dong Z, Staroselsky AH, Qi X et al. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. Cancer Res 1994; 54: 789-93.
-
(1994)
Cancer Res
, vol.54
, pp. 789-793
-
-
Dong, Z.1
Staroselsky, A.H.2
Qi, X.3
-
166
-
-
0028929559
-
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis in K-1735 murine melanoma cells
-
Xie K, Huang S, Dong Z et al. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis in K-1735 murine melanoma cells. J Exp Med 1995; 181: 1333-43.
-
(1995)
J Exp Med
, vol.181
, pp. 1333-1343
-
-
Xie, K.1
Huang, S.2
Dong, Z.3
-
167
-
-
0035113742
-
Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity
-
Chang CI, Liao JC, Kuo L. Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity. Cancer Res 2001; 61: 1100-6.
-
(2001)
Cancer Res
, vol.61
, pp. 1100-1106
-
-
Chang, C.I.1
Liao, J.C.2
Kuo, L.3
-
168
-
-
0028558753
-
Differential sensitivity to nitric oxide in immortalized, cloned murine oligodendrocyte cell lines
-
Mackenzie-Graham AJ, Mitrovic B, Smoll A et al. Differential sensitivity to nitric oxide in immortalized, cloned murine oligodendrocyte cell lines. Dev Neurosci 1994; 16: 162-71.
-
(1994)
Dev Neurosci
, vol.16
, pp. 162-171
-
-
Mackenzie-Graham, A.J.1
Mitrovic, B.2
Smoll, A.3
-
169
-
-
0034646663
-
Nitrosative capacity of macrophages is dependent on nitric-oxide synthase induction signals
-
Espey MG, Miranda KM, Pluta RM et al. Nitrosative capacity of macrophages is dependent on nitric-oxide synthase induction signals. J Biol Chem 2000; 275: 11341-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 11341-11347
-
-
Espey, M.G.1
Miranda, K.M.2
Pluta, R.M.3
-
170
-
-
0034937590
-
Cytotoxicity related to oxidative and nitrosative stress by nitric oxide
-
Wink DA, Miranda KM, Espey MG. Cytotoxicity related to oxidative and nitrosative stress by nitric oxide. Exp Biol Med (Maywood) 2001; 226: 621-3.
-
(2001)
Exp Biol Med (Maywood)
, vol.226
, pp. 621-623
-
-
Wink, D.A.1
Miranda, K.M.2
Espey, M.G.3
-
171
-
-
0029682870
-
Oxidative damage and tyrosine nitration from peroxynitrite
-
Beckman JS. Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 1996; 9: 836-44.
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 836-844
-
-
Beckman, J.S.1
-
172
-
-
0030602876
-
Protection by glutathione against the antiproliferative effects of nitric oxide. Dependence on kinetics of no release
-
Petit JF, Nicaise M, Lepoivre M et al. Protection by glutathione against the antiproliferative effects of nitric oxide. Dependence on kinetics of no release. Biochem Pharmacol 1996; 52: 205-12.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 205-212
-
-
Petit, J.F.1
Nicaise, M.2
Lepoivre, M.3
-
173
-
-
0029074495
-
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide
-
Schwarz MA, Lazo JS, Yalowich JC et al. Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide. Proc Natl Acad Sci USA 1995; 92: 4452-6.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4452-4456
-
-
Schwarz, M.A.1
Lazo, J.S.2
Yalowich, J.C.3
-
174
-
-
0029918676
-
The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistence/susceptibilty
-
Farias-Eisner R, Chaudhuri G, Aeberhard E et al. The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistence/susceptibilty. J Biol Chem 1996; 271: 6144-51.
-
(1996)
J Biol Chem
, vol.271
, pp. 6144-6151
-
-
Farias-Eisner, R.1
Chaudhuri, G.2
Aeberhard, E.3
-
175
-
-
0030986262
-
Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
-
Ambs S, Hussain SP, Harris CC. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J 1997; 11: 443-8.
-
(1997)
FASEB J
, vol.11
, pp. 443-448
-
-
Ambs, S.1
Hussain, S.P.2
Harris, C.C.3
-
176
-
-
0033135593
-
Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53
-
Shi Q, Huang S, Jiang W et al. Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53. Cancer Res 1999; 59: 2072-5.
-
(1999)
Cancer Res
, vol.59
, pp. 2072-2075
-
-
Shi, Q.1
Huang, S.2
Jiang, W.3
-
177
-
-
10544233790
-
Bcl-2 protects cytokine-induced nitric oxide-dependent apoptosis
-
Xie K, Huang S, Wang Y et al. Bcl-2 protects cytokine-induced nitric oxide-dependent apoptosis. Cancer Immunol Immunother 1996; 43: 109-15.
-
(1996)
Cancer Immunol Immunother
, vol.43
, pp. 109-115
-
-
Xie, K.1
Huang, S.2
Wang, Y.3
-
178
-
-
0344431242
-
U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation
-
Brockhaus F, Brune B. U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation. Exp Cell Res 1998; 238: 33-41.
-
(1998)
Exp Cell Res
, vol.238
, pp. 33-41
-
-
Brockhaus, F.1
Brune, B.2
-
179
-
-
0000591744
-
Bcl-2 protects macrophages from nitric oxide-induced apoptosis
-
Messmer UK, Reed UK, Brune B. Bcl-2 protects macrophages from nitric oxide-induced apoptosis. J Biol Chem 1996; 271: 20192-7.
-
(1996)
J Biol Chem
, vol.271
, pp. 20192-20197
-
-
Messmer, U.K.1
Reed, U.K.2
Brune, B.3
-
180
-
-
0030789576
-
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis
-
Sandau K, Pfeilschifter J, Brune B. Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. Kidney Int 1997; 52: 378-86.
-
(1997)
Kidney Int
, vol.52
, pp. 378-386
-
-
Sandau, K.1
Pfeilschifter, J.2
Brune, B.3
-
181
-
-
0032705798
-
2+ ion through modulation of bax, bad, and bcl-2 proteins in human colon adenocarcinoma cells
-
2+ ion through modulation of bax, bad, and bcl-2 proteins in human colon adenocarcinoma cells. Mol Carcinog 1999; 26: 201-11.
-
(1999)
Mol Carcinog
, vol.26
, pp. 201-211
-
-
Ho, Y.S.1
Liu, H.L.2
Duh, J.S.3
-
182
-
-
0033593596
-
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x
-
Ing DJ, Zang J, Dzau VJ et al. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. Circ Res 1999; 84: 21-33.
-
(1999)
Circ Res
, vol.84
, pp. 21-33
-
-
Ing, D.J.1
Zang, J.2
Dzau, V.J.3
-
183
-
-
0033276681
-
NO-Evoked macrophage apoptosis is attenuated by cAMP-induced gene expression
-
von Knethen A, Brockhaus F, Kleiter I et al. NO-Evoked macrophage apoptosis is attenuated by cAMP-induced gene expression. Mol Med 1999; 5: 672-84.
-
(1999)
Mol Med
, vol.5
, pp. 672-684
-
-
Von Knethen, A.1
Brockhaus, F.2
Kleiter, I.3
-
184
-
-
0033627736
-
Nitric oxide-mediated apoptosis in human breast cancer cells requires changes in mitochondrial functions and is independent of CD95 (APO-1/Fas)
-
Umansky V, Ushmorov A, Ratter F et al. Nitric oxide-mediated apoptosis in human breast cancer cells requires changes in mitochondrial functions and is independent of CD95 (APO-1/Fas). Int J Oncol 2000; 16: 109-17.
-
(2000)
Int J Oncol
, vol.16
, pp. 109-117
-
-
Umansky, V.1
Ushmorov, A.2
Ratter, F.3
-
185
-
-
0032100446
-
Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells
-
Chlichlia K, Peter ME, Rocha M et al. Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells. Blood 1998; 91: 4311-20.
-
(1998)
Blood
, vol.91
, pp. 4311-4320
-
-
Chlichlia, K.1
Peter, M.E.2
Rocha, M.3
-
186
-
-
0031031148
-
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression
-
Kim YM, de Vera ME, Watkins SC et al. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by
-
(1997)
J Biol Chem
, vol.272
, pp. 1402-1411
-
-
Kim, Y.M.1
De Vera, M.E.2
Watkins, S.C.3
-
187
-
-
0034769244
-
Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: Role of nitric oxide-induced heat shock protein 70 expression
-
Nisoli E, Regianini L, Bulbarelli A et al. Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: Role of nitric oxide-induced heat shock protein 70 expression. Int J Obes Relat Metab Disord 2001; 25: 1421-30.
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, pp. 1421-1430
-
-
Nisoli, E.1
Regianini, L.2
Bulbarelli, A.3
-
188
-
-
0028658374
-
Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein - Barr virus reactivation
-
Mannick JB, Asano K, Izumi K et al. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein - Barr virus reactivation. Cell 1994; 79: 1137-46.
-
(1994)
Cell
, vol.79
, pp. 1137-1146
-
-
Mannick, J.B.1
Asano, K.2
Izumi, K.3
-
189
-
-
0028917191
-
Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels
-
Genaro AM, Hortelano S, Alvarez A et al. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J Clin Invest 1995; 95: 1884-90.
-
(1995)
J Clin Invest
, vol.95
, pp. 1884-1890
-
-
Genaro, A.M.1
Hortelano, S.2
Alvarez, A.3
-
190
-
-
0030918451
-
Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor pro-drag that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver
-
Saavedra JE, Billiar TR, Williams DL et al. Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor pro-drag that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver. J Med Chem 1997; 40: 1947-54.
-
(1997)
J Med Chem
, vol.40
, pp. 1947-1954
-
-
Saavedra, J.E.1
Billiar, T.R.2
Williams, D.L.3
-
191
-
-
0031855881
-
Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis
-
Tzeng E, Billiar TR, Williams DL et al. Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis. Surgery 1998; 124: 278-83.
-
(1998)
Surgery
, vol.124
, pp. 278-283
-
-
Tzeng, E.1
Billiar, T.R.2
Williams, D.L.3
-
192
-
-
0031923844
-
Role of nitric oxide in 1L-2 therapy-induced capillary leak syndrome
-
Orucevic A, Lala PK. Role of nitric oxide in 1L-2 therapy-induced capillary leak syndrome. Cancer Metastasis Rev 1998; 17: 127-42.
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 127-142
-
-
Orucevic, A.1
Lala, P.K.2
-
193
-
-
0035296203
-
Role of nitric oxide in carcinogenesis and tumor progression
-
Lala PK, Chakraborty C. Role of nitric oxide in carcinogenesis and tumor progression. Lancet Oncol 2001; 2: 149-56.
-
(2001)
Lancet Oncol
, vol.2
, pp. 149-156
-
-
Lala, P.K.1
Chakraborty, C.2
-
194
-
-
0031003224
-
Destruction of bystander cells by tumor cells transfected with the inducible nitric oxide synthase gene
-
Xie K, Huang S, Dong Z et al. Destruction of bystander cells by tumor cells transfected with the inducible nitric oxide synthase gene. J Natl Cancer Inst 1997; 89: 421-7.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 421-427
-
-
Xie, K.1
Huang, S.2
Dong, Z.3
-
195
-
-
0001517847
-
Transfection of interleukin-10 suppresses tumorigenicity and metastasis of human melanoma by inhibiting angiogenesis
-
Huang S, Xie K, Ullrich SE et al. Transfection of interleukin-10 suppresses tumorigenicity and metastasis of human melanoma by inhibiting angiogenesis. Clin Cancer Res 1996; 2: 1961-79.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1961-1979
-
-
Huang, S.1
Xie, K.2
Ullrich, S.E.3
-
196
-
-
0031780623
-
Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide
-
Kundu N, Dorsey R, Jackso MJ et al. Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide. Int J Cancer 1998; 76: 713-9.
-
(1998)
Int J Cancer
, vol.76
, pp. 713-719
-
-
Kundu, N.1
Dorsey, R.2
Jackso, M.J.3
-
197
-
-
0033972177
-
Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages
-
Bruns CJ, Shinohara H, Harbison MT et al. Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages. Cancer Res 2000; 60: 2-7.
-
(2000)
Cancer Res
, vol.60
, pp. 2-7
-
-
Bruns, C.J.1
Shinohara, H.2
Harbison, M.T.3
-
198
-
-
0028059949
-
Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidylserine
-
Calderon C, Huang ZH, Gage DA et al. Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidylserine. J Exptl Med 1995; 180: 945-58.
-
(1995)
J Exptl Med
, vol.180
, pp. 945-958
-
-
Calderon, C.1
Huang, Z.H.2
Gage, D.A.3
-
199
-
-
0032503018
-
Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the marine inducible nitric oxide synthase gene
-
Juang S-H, Xie K, Xu L et al. Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retrviral vectors harboring the marine inducible nitric oxide synthase gene. Human Gene Ther 1998; 9: 845-54.
-
(1998)
Human Gene Ther
, vol.9
, pp. 845-854
-
-
Juang, S.-H.1
Xie, K.2
Xu, L.3
-
200
-
-
0026734114
-
Extrapolations from laboratory and preclinical studies for the use of carbogen and nicotinamide in radiotherapy
-
Rojas A, Joiner MC, Denekamp J. Extrapolations from laboratory and preclinical studies for the use of carbogen and nicotinamide in radiotherapy. Radiother Oncol 1992; 24: 1234.
-
(1992)
Radiother Oncol
, vol.24
, pp. 1234
-
-
Rojas, A.1
Joiner, M.C.2
Denekamp, J.3
-
201
-
-
0033995077
-
Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation
-
Fenton BM, Lord EM, Paoni SF. Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation. Radiat Res 2000; 153: 75-83.
-
(2000)
Radiat Res
, vol.153
, pp. 75-83
-
-
Fenton, B.M.1
Lord, E.M.2
Paoni, S.F.3
-
202
-
-
0033214120
-
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: Hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide
-
Hoskin PJ, Saunders MI, Dische S. Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: Hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide. Cancer 1999; 86: 1322-8.
-
(1999)
Cancer
, vol.86
, pp. 1322-1328
-
-
Hoskin, P.J.1
Saunders, M.I.2
Dische, S.3
-
203
-
-
0032887406
-
Accelerated radiotherapy, carbogen, and nicotinamide in glioblastoma multiforme: Report of European Organization for Research and Treatment of Cancer trial 22933
-
Miralbell R, Mornex F, Greiner R et al. Accelerated radiotherapy, carbogen, and nicotinamide in glioblastoma multiforme: Report of European Organization for Research and Treatment of Cancer trial 22933. J Clin Oncol 1999; 17: 3143-9.
-
(1999)
J Clin Oncol
, vol.17
, pp. 3143-3149
-
-
Miralbell, R.1
Mornex, F.2
Greiner, R.3
-
204
-
-
0030069889
-
Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
-
Overgaard J, Horsman MR. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 1996; 6: 10-21.
-
(1996)
Semin Radiat Oncol
, vol.6
, pp. 10-21
-
-
Overgaard, J.1
Horsman, M.R.2
-
205
-
-
0029976702
-
Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide
-
Saunders M, Dische S. Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br J Cancer Suppl 1996; 27: S271-8.
-
(1996)
Br J Cancer Suppl
, vol.27
-
-
Saunders, M.1
Dische, S.2
-
206
-
-
0034306888
-
A phase I/II evaluation of tirapazamine administered intravenously concurrent with cisplatin and radiotherapy in women with locally advanced cervical cancer
-
Craighead PS, Pearcey R, Stuart G. A phase I/II evaluation of tirapazamine administered intravenously concurrent with cisplatin and radiotherapy in women with locally advanced cervical cancer. Int J Radiat Oncol Biol Phys 2000; 48: 791-5.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 791-795
-
-
Craighead, P.S.1
Pearcey, R.2
Stuart, G.3
-
207
-
-
0033063810
-
Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin
-
Kovacs MS, Hocking DJ, Evans JW et al. Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin. Br J Cancer 1999; 80: 1245-51.
-
(1999)
Br J Cancer
, vol.80
, pp. 1245-1251
-
-
Kovacs, M.S.1
Hocking, D.J.2
Evans, J.W.3
-
208
-
-
0034543132
-
AQ4N: A new approach to hypoxia-activated cancer chemotherapy
-
Patterson LH, McKeown SR. AQ4N: A new approach to hypoxia-activated cancer chemotherapy. Br J Cancer 2000; 83: 1589-93.
-
(2000)
Br J Cancer
, vol.83
, pp. 1589-1593
-
-
Patterson, L.H.1
McKeown, S.R.2
-
209
-
-
0034032620
-
Bifidobacterium longum as a delivery system for cancer gene therapy: Selective localization and growth in hypoxic tumors
-
Yazawa K, Fujimori M, Amano J et al. Bifidobacterium longum as a delivery system for cancer gene therapy: Selective localization and growth in hypoxic tumors. Cancer Gene Ther 2000; 7: 269-74.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 269-274
-
-
Yazawa, K.1
Fujimori, M.2
Amano, J.3
-
210
-
-
0035014279
-
The use of radiation-induced bacterial promoters in anaerobic conditions: A means to control gene expression in clostridium-mediated therapy for cancer
-
Nuyts S, Van Mellaert L, Theys J et al. The use of radiation-induced bacterial promoters in anaerobic conditions: A means to control gene expression in clostridium-mediated therapy for cancer. Radiat Res 2001; 155: 716-23.
-
(2001)
Radiat Res
, vol.155
, pp. 716-723
-
-
Nuyts, S.1
Van Mellaert, L.2
Theys, J.3
-
211
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: Therapeutic implications. N Engl J Med 1971; 285: 1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
212
-
-
0025093973
-
Vascular attack as a therapeutic strategy for cancer
-
Denekamp J. Vascular attack as a therapeutic strategy for cancer. Cancer Metastasis Rev 1990; 9: 267-82.
-
(1990)
Cancer Metastasis Rev
, vol.9
, pp. 267-282
-
-
Denekamp, J.1
-
213
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-64.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
214
-
-
0031805836
-
An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo
-
Asano M, Yukita A, Matsumoto T et al. An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo. Hybridoma 1998; 17: 185-90.
-
(1998)
Hybridoma
, vol.17
, pp. 185-190
-
-
Asano, M.1
Yukita, A.2
Matsumoto, T.3
-
215
-
-
0028972105
-
Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
-
Brooks PC, Stromblad S, Klemke R et al. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest 1995; 96: 1815-22.
-
(1995)
J Clin Invest
, vol.96
, pp. 1815-1822
-
-
Brooks, P.C.1
Stromblad, S.2
Klemke, R.3
-
216
-
-
0034017489
-
Development of a hypoxia-responsive vector for tumor-specific gene therapy
-
Shibata T, Giaccia AJ, Brown JM. Development of a hypoxia-responsive vector for tumor-specific gene therapy. Gene Ther 2000; 7: 493-8.
-
(2000)
Gene Ther
, vol.7
, pp. 493-498
-
-
Shibata, T.1
Giaccia, A.J.2
Brown, J.M.3
-
217
-
-
0034529914
-
Suppression of tumor growth through disruption of hypoxia-inducible transcription
-
Kung AL, Wang S, Klco JM et al. Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med 2000; 6: 1335-40.
-
(2000)
Nat Med
, vol.6
, pp. 1335-1340
-
-
Kung, A.L.1
Wang, S.2
Klco, J.M.3
-
218
-
-
0033867776
-
Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
-
Dachs GU, Tozer GM. Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer 2000; 36: 1649-60.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1649-1660
-
-
Dachs, G.U.1
Tozer, G.M.2
-
219
-
-
0035341494
-
Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-kappaB
-
Russo SM, Tepper JE, Baldwin AS, Jr et al. Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-kappaB. Int J Radiat Oncol Biol Phys 2001; 50: 183-193.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 183-193
-
-
Russo, S.M.1
Tepper, J.E.2
Baldwin A.S., Jr.3
|