-
3
-
-
0030742027
-
Tumour hypoxia adversely affects the prognosis of carcinoma of the head and neck
-
Brizel D.M., Sibley G.S., Prosnitz L.R., Scher R.L., Dewhirst M.W. Tumour hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 38:1997;285-289.
-
(1997)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.38
, pp. 285-289
-
-
Brizel, D.M.1
Sibley, G.S.2
Prosnitz, L.R.3
Scher, R.L.4
Dewhirst, M.W.5
-
4
-
-
0002556909
-
Oxygenation of human tumors: The Munich/Halle experience
-
P. Vaupel, & D.K. Kelleher. Stuttgart: Wissenschaftliche Verlagsgesellschaft mbH
-
Dunst J., Feldmann H.J., Becker A., Stadler P., Haensgen G., Molls M. Oxygenation of human tumors. the Munich/Halle experience Vaupel P., Kelleher D.K. Tumour Hypoxia: Pathophysiology, Clinical Significance and Therapeutic Perspectives. 1999;Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart.
-
(1999)
Tumour Hypoxia: Pathophysiology, Clinical Significance and Therapeutic Perspectives
-
-
Dunst, J.1
Feldmann, H.J.2
Becker, A.3
Stadler, P.4
Haensgen, G.5
Molls, M.6
-
5
-
-
0027477360
-
Oxygenation of head and neck tumours
-
Lartigau E., Le Ridant A.M., Lambin P.et al. Oxygenation of head and neck tumours. Cancer. 71:1993;2319-2325.
-
(1993)
Cancer
, vol.71
, pp. 2319-2325
-
-
Lartigau, E.1
Le Ridant, A.M.2
Lambin, P.3
-
6
-
-
0028242772
-
Measurement of human tumor oxygenation status by a polarographic needle electrode. An analysis of inter- And intratumor heterogeneity
-
Nordsmark M., Bentzen S.M., Overgaard J. Measurement of human tumor oxygenation status by a polarographic needle electrode. An analysis of inter- and intratumor heterogeneity. Acta. Oncol. 33:1994;383-389.
-
(1994)
Acta. Oncol.
, vol.33
, pp. 383-389
-
-
Nordsmark, M.1
Bentzen, S.M.2
Overgaard, J.3
-
8
-
-
0026763113
-
Feasibility of measuring oxygen tension in uterine cervix carcinoma
-
Lartigau E., Vitu L., Haie-Meder C.et al. Feasibility of measuring oxygen tension in uterine cervix carcinoma. Eur. J. Cancer. 28A:1992;1354-1357.
-
(1992)
Eur. J. Cancer
, vol.28
, pp. 1354-1357
-
-
Lartigau, E.1
Vitu, L.2
Haie-Meder, C.3
-
10
-
-
0023107539
-
Intermittent blood flow in a murine tumor: Radiobiological effects
-
Chaplin D.J., Olive P.L., Durand R.E. Intermittent blood flow in a murine tumor. radiobiological effects Cancer Res. 47:1987;597-601.
-
(1987)
Cancer Res.
, vol.47
, pp. 597-601
-
-
Chaplin, D.J.1
Olive, P.L.2
Durand, R.E.3
-
11
-
-
0029024240
-
Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours
-
Chaplin D.J., Hill S.A. Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours. Br. J. Cancer. 71:1995;1210-1213.
-
(1995)
Br. J. Cancer
, vol.71
, pp. 1210-1213
-
-
Chaplin, D.J.1
Hill, S.A.2
-
12
-
-
0025329088
-
Oxygenation of human tumors
-
Vaupel P. Oxygenation of human tumors. Strahlenther. Oncol. 166:1990;377-386.
-
(1990)
Strahlenther. Oncol.
, vol.166
, pp. 377-386
-
-
Vaupel, P.1
-
14
-
-
0002243310
-
Human tumor oxygenation: The Duke University Medical Center experience
-
P. Vaupel, & D.K. Kelleher. Wissenschaftliche Verlagsgesellschaft mbH: Stuttgart
-
Brizel D.M. Human tumor oxygenation. the Duke University Medical Center experience Vaupel P., Kelleher D.K. Tumour Hypoxia: Pathophysiology, Clinical Significance and Therapeutic Perspectives. 1999;Stuttgart, Wissenschaftliche Verlagsgesellschaft mbH.
-
(1999)
Tumour Hypoxia: Pathophysiology, Clinical Significance and Therapeutic Perspectives
-
-
Brizel, D.M.1
-
16
-
-
0028632781
-
Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
-
Overgaard J. Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors. Oncol. Res. 6:1994;509-518.
-
(1994)
Oncol. Res.
, vol.6
, pp. 509-518
-
-
Overgaard, J.1
-
18
-
-
0029775242
-
Association between tumour hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hoeckel M., Schlenger K., Aral B., Mitze M., Schaeffer U., Vaupel P. Association between tumour hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56:1996;4509-4515.
-
(1996)
Cancer Res.
, vol.56
, pp. 4509-4515
-
-
Hoeckel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaeffer, U.5
Vaupel, P.6
-
19
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel D.M., Scully S.P., Harrelson J.M.et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res. 56:1996;941-943.
-
(1996)
Cancer Res.
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
20
-
-
0000901812
-
Hypoxia in human soft tissue sarcomas is associated with poor survival
-
Nordsmark M., Keller J., Hoyer M., Nielson O.S., Jensen O.M., Overgaard J. Hypoxia in human soft tissue sarcomas is associated with poor survival. Radiother. Oncol. 48(Suppl. 1):1998;S162.
-
(1998)
Radiother. Oncol.
, vol.48
, pp. 162
-
-
Nordsmark, M.1
Keller, J.2
Hoyer, M.3
Nielson, O.S.4
Jensen, O.M.5
Overgaard, J.6
-
21
-
-
0031716020
-
Oxygenation predicts radiation response and survival in patients with cervix cancer
-
Fyles A.W., Milosevic M., Wong R.et al. Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother. Oncol. 48:1998;149-156.
-
(1998)
Radiother. Oncol.
, vol.48
, pp. 149-156
-
-
Fyles, A.W.1
Milosevic, M.2
Wong, R.3
-
22
-
-
0037480606
-
Hypoxic cervical cancers with low apoptotic index are highly aggressive
-
Hoeckel M., Schlenger K., Hoeckel S., Vaupel P. Hypoxic cervical cancers with low apoptotic index are highly aggressive. Cancer Res. 59:1999;4525-4528.
-
(1999)
Cancer Res.
, vol.59
, pp. 4525-4528
-
-
Hoeckel, M.1
Schlenger, K.2
Hoeckel, S.3
Vaupel, P.4
-
23
-
-
0031688165
-
Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix
-
Sundfor K., Lyng H., Rofstad E.K. Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix. Br. J. Cancer. 78:1998;822-827.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 822-827
-
-
Sundfor, K.1
Lyng, H.2
Rofstad, E.K.3
-
24
-
-
0031059664
-
Exposure to hypoxia, glucose starvation and acidosis: Effect on invasive capacity of murine tumor cells and correlation with cathepsin (L+B) secretion
-
Cuvier C., Jang A., Hill R.P. Exposure to hypoxia, glucose starvation and acidosis. Effect on invasive capacity of murine tumor cells and correlation with cathepsin (L+B) secretion Clin. Exp. Metastasis. 15:1997;19-25.
-
(1997)
Clin. Exp. Metastasis
, vol.15
, pp. 19-25
-
-
Cuvier, C.1
Jang, A.2
Hill, R.P.3
-
25
-
-
0031029634
-
Correlation of high lactate levels in head and neck tumors with incidence of metastasis
-
Walenta S., Salameh A., Lyng H.et al. Correlation of high lactate levels in head and neck tumors with incidence of metastasis. Am. J. Pathol. 150:1997;409-415.
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 409-415
-
-
Walenta, S.1
Salameh, A.2
Lyng, H.3
-
26
-
-
0029689905
-
Tumoral vascularity as a prognostic factor in cancer
-
V.T. DeVita. Philadelphia: Lippincott-Raven
-
Weidner N., Folkman J. Tumoral vascularity as a prognostic factor in cancer. DeVita V.T. Important Advances in Oncology. 1996;167-190 Lippincott-Raven, Philadelphia.
-
(1996)
Important Advances in Oncology
, pp. 167-190
-
-
Weidner, N.1
Folkman, J.2
-
27
-
-
0029753008
-
Activation of hypoxia inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang L.E., Arany Z., Livingston D.M.et al. Activation of hypoxia inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J. Biol. Chem. 271:1996;32253-32259.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
-
28
-
-
0028129435
-
Regulation of c-jun expression during hypoxic and low-glucose stress
-
Ausserer W.A., Bourrat-Floeck B., Green C.J.et al. Regulation of c-jun expression during hypoxic and low-glucose stress. Mol. Cell. Biol. 14:1994;5032-5042.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5032-5042
-
-
Ausserer, W.A.1
Bourrat-Floeck, B.2
Green, C.J.3
-
29
-
-
0028268629
-
Hypoxia causes the activation of nuclear factor κb through phosphorylation of IκBα on tyrosine residues
-
Koong A.C., Chen E.Y., Giaccia A.J. Hypoxia causes the activation of nuclear factor κB through phosphorylation of IκBα on tyrosine residues. Cancer Res. 54:1994;1425-1430.
-
(1994)
Cancer Res.
, vol.54
, pp. 1425-1430
-
-
Koong, A.C.1
Chen, E.Y.2
Giaccia, A.J.3
-
30
-
-
0028110809
-
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status
-
Graeber T.G., Peterson J.F., Tsai M.et al. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status. Mol. Cell. Biol. 14:1994;6264-6277.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
-
31
-
-
0025972125
-
Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events
-
Goldberg M.A., Gaut C.C., Bunn H.F. Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events. Blood. 77:1991;271.
-
(1991)
Blood
, vol.77
, pp. 271
-
-
Goldberg, M.A.1
Gaut, C.C.2
Bunn, H.F.3
-
32
-
-
0027230099
-
A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer
-
Madan A., Curtin P.T. A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer. Proc. Natl. Acad. Sci. USA. 90:1993;3928-3932.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3928-3932
-
-
Madan, A.1
Curtin, P.T.2
-
33
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D., Itin A., Soffer D.et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:1992;843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
-
34
-
-
0029165446
-
Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability
-
Shima D.T., Deutsch U., D'Amore P.A. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS. Lett. 370:1995;203-208.
-
(1995)
FEBS. Lett.
, vol.370
, pp. 203-208
-
-
Shima, D.T.1
Deutsch, U.2
D'Amore, P.A.3
-
35
-
-
0030961524
-
Sequencing of the human vascular endothelial growth factor (VEGF) 3′ untranslated region (UTR): Conservation of five hypoxia-inducible RNA-protein binding sites
-
Levy N.S., Goldberg M.A., Levy A.P. Sequencing of the human vascular endothelial growth factor (VEGF) 3′ untranslated region (UTR). conservation of five hypoxia-inducible RNA-protein binding sites Biochem. Biophys. Acta. 1352:1997;167-173.
-
(1997)
Biochem. Biophys. Acta.
, vol.1352
, pp. 167-173
-
-
Levy, N.S.1
Goldberg, M.A.2
Levy, A.P.3
-
36
-
-
0031058350
-
The influence of oxygen tension and pH on the expression of platelet derived endothelial cell growth factor/thymidine phosphorylase in human breast tumour cells grown in vitro and in vivo
-
Griffiths L., Dachs G.U., Bicknell R.et al. The influence of oxygen tension and pH on the expression of platelet derived endothelial cell growth factor/thymidine phosphorylase in human breast tumour cells grown in vitro and in vivo. Cancer Res. 57:1997;570-572.
-
(1997)
Cancer Res.
, vol.57
, pp. 570-572
-
-
Griffiths, L.1
Dachs, G.U.2
Bicknell, R.3
-
37
-
-
0029353573
-
Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung
-
Shaul P.W., North A.J., Brannon T.S.et al. Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung. Am. J. Respir. Cell. Mol. Biol. 13:1995;167-174.
-
(1995)
Am. J. Respir. Cell. Mol. Biol.
, vol.13
, pp. 167-174
-
-
Shaul, P.W.1
North, A.J.2
Brannon, T.S.3
-
38
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranslational mechanisms
-
McQuillan L.P., Leung G.K., Marsden P.A., Kostyk S.K., Kourembanas S. Hypoxia inhibits expression of eNOS via transcriptional and posttranslational mechanisms. Am. J. Physiol. 267:1994;H1921-H1927.
-
(1994)
Am. J. Physiol.
, vol.267
, pp. 1921-H1927
-
-
McQuillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
Kostyk, S.K.4
Kourembanas, S.5
-
39
-
-
0342839945
-
Hypoxia stimulates NFκB mediated iNOS expression in tumour endothelial cells
-
Stark W.W., Wasserloos K., Modzelewski R.et al. Hypoxia stimulates NFκB mediated iNOS expression in tumour endothelial cells. Mol. Biol. Cell. 6:1995;438.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 438
-
-
Stark, W.W.1
Wasserloos, K.2
Modzelewski, R.3
-
40
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo G., Musso T., Sica A., Taylor L.S., Cox G.W., Varesio L. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med. 182:1995;1683-1693.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
Taylor, L.S.4
Cox, G.W.5
Varesio, L.6
-
41
-
-
0030911247
-
Functional requirement of the hypoxia responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine
-
Melillo G., Taylor L.S., Brooks A.et al. Functional requirement of the hypoxia responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine. J. Biol. Chem. 272:1997;12236-12243.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12236-12243
-
-
Melillo, G.1
Taylor, L.S.2
Brooks, A.3
-
42
-
-
0032576971
-
Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
-
Hu J., Disher D.J., Bishopric N.H., Webster K.A. Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand. Biochem. Biophys. Res. Comm. 245:1998;894-899.
-
(1998)
Biochem. Biophys. Res. Comm.
, vol.245
, pp. 894-899
-
-
Hu, J.1
Disher, D.J.2
Bishopric, N.H.3
Webster, K.A.4
-
43
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn H.F., Poyton R.O. Oxygen sensing and molecular adaptation to hypoxia. Physiol. Rev. 76:1996;839-885.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
44
-
-
0031926560
-
Microenvironmental control of gene expression: Implications for tumour angiogenesis, progression, and metastasis
-
Dachs G.U., Chaplin D.J. Microenvironmental control of gene expression. implications for tumour angiogenesis, progression, and metastasis Semin. Radiat. Oncol. 8:1998;208-216.
-
(1998)
Semin. Radiat. Oncol.
, vol.8
, pp. 208-216
-
-
Dachs, G.U.1
Chaplin, D.J.2
-
45
-
-
0027172514
-
Characterisation of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-kD-a nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells
-
Beck I., Weinmann R., Caro J. Characterisation of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-kD-a nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells. Blood. 82:1993;704-711.
-
(1993)
Blood
, vol.82
, pp. 704-711
-
-
Beck, I.1
Weinmann, R.2
Caro, J.3
-
46
-
-
0027427588
-
Characterization of hypoxia-inducible factor-1 and regulation of DNA-binding activity by hypoxia
-
Wang G.L., Semenza G.L. Characterization of hypoxia-inducible factor-1 and regulation of DNA-binding activity by hypoxia. J. Biol. Chem. 268:1993;21513-21518.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
48
-
-
0027210562
-
General involvement of hypoxia-inducible factor-1 in transcriptional response to hypoxia
-
Wang G.L., Semenza G.L. General involvement of hypoxia-inducible factor-1 in transcriptional response to hypoxia. Proc. Natl. Acad. Sci. USA. 90:1993;4304-4308.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
49
-
-
0027461553
-
Inducible operation of the erythopoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen sensing mechanism
-
Maxwell P.H., Pugh C.W., Ratcliffe P.J. Inducible operation of the erythopoietin 3′ enhancer in multiple cell lines. evidence for a widespread oxygen sensing mechanism Proc. Natl. Acad. Sci. USA. 90:1993;2423-2427.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2423-2427
-
-
Maxwell, P.H.1
Pugh, C.W.2
Ratcliffe, P.J.3
-
50
-
-
0030583293
-
In vivo expression of messenger RNAs encoding hypoxia inducible factor-1
-
Wiener C.M., Booth G., Semenza G.L. In vivo expression of messenger RNAs encoding hypoxia inducible factor-1. Biochem. Biophys. Res. Commun. 225:1996;485-488.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 485-488
-
-
Wiener, C.M.1
Booth, G.2
Semenza, G.L.3
-
51
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastasis
-
Zhong H., DeMarzo A.M., Laughner E.et al. Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastasis. Cancer Res. 59:1999;5830-5835.
-
(1999)
Cancer Res.
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
Demarzo, A.M.2
Laughner, E.3
-
52
-
-
0032403263
-
Increased expression of hypoxia inducible factor 1α in rat and human prostate cancer
-
Zhong H., Agani F., Baccala A.A.et al. Increased expression of hypoxia inducible factor 1α in rat and human prostate cancer. Cancer Res. 58:1998;5280-5284.
-
(1998)
Cancer Res.
, vol.58
, pp. 5280-5284
-
-
Zhong, H.1
Agani, F.2
Baccala, A.A.3
-
53
-
-
0029789568
-
Functional interference between hypoxia and dioxin signal transduction pathways- competition for recruitment of the ARNT transcription factor
-
Gradin K., McGuire J., Wenger R.H.et al. Functional interference between hypoxia and dioxin signal transduction pathways- competition for recruitment of the ARNT transcription factor. Mol. Cell. Biol. 16:1996;5221-5231.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5221-5231
-
-
Gradin, K.1
McGuire, J.2
Wenger, R.H.3
-
54
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
Arany Z., Huang L.E., Eckner R.et al. An essential role for p300/CBP in the cellular response to hypoxia. Proc. Natl. Acad. Sci. USA. 93:1996;12969-12973.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
-
55
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W.et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 399:1999;271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
56
-
-
0031835957
-
Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, and adjacent transcription factor, and p300/CREB binding protein
-
Ebert B.L., Bunn H.F. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, and adjacent transcription factor, and p300/CREB binding protein. Mol. Cell. Biol. 18:1998;4089-4096.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4089-4096
-
-
Ebert, B.L.1
Bunn, H.F.2
-
57
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor 1α
-
Kallio P.J., Okamoto K., O'Brien S.et al. Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor 1α EMBO J. 17:1998;6573-6586.
-
(1998)
EMBO J.
, vol.17
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'Brien, S.3
-
58
-
-
0032749463
-
Hypoxia-induced activation of HIF-1, role of HIF-1α-Hsp90 interaction
-
Minet E., Mottet D., Michel G.et al. Hypoxia-induced activation of HIF-1, role of HIF-1α-Hsp90 interaction. FEBS. Lett. 460:1999;251-256.
-
(1999)
FEBS. Lett.
, vol.460
, pp. 251-256
-
-
Minet, E.1
Mottet, D.2
Michel, G.3
-
59
-
-
0029795584
-
Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel Lindau protein
-
Levy A.P., Levy N.S., Goldberg M.A. Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel Lindau protein. J. Biol. Chem. 271:1996;25492-25497.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25492-25497
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
-
60
-
-
0033585496
-
AHIF: A natural antisense transcript overexpressed in human renal cancer and during hypoxia
-
ThrashBingham C.A., Tartof K.D. aHIF. a natural antisense transcript overexpressed in human renal cancer and during hypoxia J. Natl. Cancer Inst. 91:1999;143-151.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 143-151
-
-
Thrashbingham, C.A.1
Tartof, K.D.2
-
61
-
-
0033986948
-
Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor-1α
-
Carrero P., Okamoto K., Coumailleau P., O'Brien S., Tanaka H., Poellinger L. Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor-1α Mol. Cell. Biol. 20:2000;402-415.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 402-415
-
-
Carrero, P.1
Okamoto, K.2
Coumailleau, P.3
O'Brien, S.4
Tanaka, H.5
Poellinger, L.6
-
62
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
Tian H., McKnight S.L., Russell D.W. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 11:1997;72-82.
-
(1997)
Genes Dev.
, vol.11
, pp. 72-82
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
63
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia inducible factor1 alpha regulates VEGF expression and is potentially involved in lung and vascular development
-
Ema M., Taya S., Yokotani N.et al. A novel bHLH-PAS factor with close sequence similarity to hypoxia inducible factor1 alpha regulates VEGF expression and is potentially involved in lung and vascular development. Proc. Natl. Acad. Sci. USA. 94:1997;4273-4278.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
-
65
-
-
0033525830
-
Regulation of the hypoxia-inducible factor-1α by the ubiquitin-proteasome pathway
-
Kallio P.J., Wilson W.J., O'Brien S., Makino Y., Poellinger L. Regulation of the hypoxia-inducible factor-1α by the ubiquitin-proteasome pathway. J. Biol. Chem. 274:1999;6519-6525.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6519-6525
-
-
Kallio, P.J.1
Wilson, W.J.2
O'Brien, S.3
Makino, Y.4
Poellinger, L.5
-
66
-
-
0032891708
-
Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): Heterodimerisation with ARNT is not necessary for nuclear accumulation of HIF-1α
-
Chilov D., Camenish G., Kvietikova I., Ziegler U., Gassmann M., Wenger R.H. Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1). heterodimerisation with ARNT is not necessary for nuclear accumulation of HIF-1α J. Cell Sci. 112:1999;1203-1212.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 1203-1212
-
-
Chilov, D.1
Camenish, G.2
Kvietikova, I.3
Ziegler, U.4
Gassmann, M.5
Wenger, R.H.6
-
67
-
-
0030816109
-
Hypoxia inducible factor-1 modulates gene expression in solid tumours and influences both angiogenesis and tumour growth
-
Maxwell P.H., Dachs G.U., Gleadle J.M.et al. Hypoxia inducible factor-1 modulates gene expression in solid tumours and influences both angiogenesis and tumour growth. Proc. Natl. Acad. Sci. USA. 94:1997;8104-8109.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
-
68
-
-
0003874399
-
Hypoxia-mediated gene expression
-
P. Vaupel, & D.K. Kelleher. Stuttgart: Wissenschaftliche Verlagsgesellschaft mbH
-
Stratford I.J., Patterson A.V., Dachs G.U., Telfer B., Williams K.J. Hypoxia-mediated gene expression. Vaupel P., Kelleher D.K. Tumour Hypoxia. 1999;107-113 Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart.
-
(1999)
Tumour Hypoxia
, pp. 107-113
-
-
Stratford, I.J.1
Patterson, A.V.2
Dachs, G.U.3
Telfer, B.4
Williams, K.J.5
-
70
-
-
0032581277
-
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
-
Carmeliet P., Dor Y., Herbert J.M.et al. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis. Nature. 394:1998;485-490.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
-
71
-
-
0032079558
-
Oxygen-regulated erythropoietin expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site
-
Wenger R.H., Kvietikova I., Rolfs A., Camenish G., Gassmann M. Oxygen-regulated erythropoietin expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur. J. Biochem. 253:1998;771-777.
-
(1998)
Eur. J. Biochem.
, vol.253
, pp. 771-777
-
-
Wenger, R.H.1
Kvietikova, I.2
Rolfs, A.3
Camenish, G.4
Gassmann, M.5
-
72
-
-
0030025773
-
Hypoxia mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber T.G., Osmanian C., Jacks T.et al. Hypoxia mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 379:1996;88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
73
-
-
0032524285
-
P53 inhibits hypoxia-inducible factor-stimulated transcription
-
Blagosklonny M.V., An W.G., Romanova L.Y., Trepel J., Fojo T., Neckers L. p53 inhibits hypoxia-inducible factor-stimulated transcription. J. Biol. Chem. 273:1998;1195-11998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1195-11998
-
-
Blagosklonny, M.V.1
An, W.G.2
Romanova, L.Y.3
Trepel, J.4
Fojo, T.5
Neckers, L.6
-
74
-
-
0032535077
-
Upregulation of hypoxia-inducible factor 1α is not sufficient for hypoxic/anoxic p53 induction
-
Wenger R.H., Camenish G., Desbaillets I., Chilov D., Gassmann M. Upregulation of hypoxia-inducible factor 1α is not sufficient for hypoxic/anoxic p53 induction. Cancer Res. 58:1998;5678-5680.
-
(1998)
Cancer Res.
, vol.58
, pp. 5678-5680
-
-
Wenger, R.H.1
Camenish, G.2
Desbaillets, I.3
Chilov, D.4
Gassmann, M.5
-
75
-
-
0033954247
-
Regulation of tumour angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
-
Ravi R., Mookerjee B., Bhujwalla Z.M.et al. Regulation of tumour angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α Gene Dev. 14:2000;34-44.
-
(2000)
Gene Dev.
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
-
76
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate K.H., Breier G., Weich H.A.et al. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 359:1992;845-848.
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
-
77
-
-
0027432324
-
Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis
-
Plate K.H., Breier G., Millauer B.et al. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis. Cancer Res. 53:1993;5822-5827.
-
(1993)
Cancer Res.
, vol.53
, pp. 5822-5827
-
-
Plate, K.H.1
Breier, G.2
Millauer, B.3
-
78
-
-
0030829035
-
Enhanced expression of vascular endothelial growth factor in metastatic melanoma
-
Salven P., Heikkila P., Joensuu H. Enhanced expression of vascular endothelial growth factor in metastatic melanoma. Br. J. Cancer. 76:1997;930-934.
-
(1997)
Br. J. Cancer
, vol.76
, pp. 930-934
-
-
Salven, P.1
Heikkila, P.2
Joensuu, H.3
-
79
-
-
0033010512
-
Vascular endothelial growth factor is upregulated in early premalignant stage of colorectal tumour progression
-
Wong M.P., Cheung N., Yuen S.T., Leung S.Y., Chung L.P. Vascular endothelial growth factor is upregulated in early premalignant stage of colorectal tumour progression. Int. J. Cancer. 81:1999;845-850.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 845-850
-
-
Wong, M.P.1
Cheung, N.2
Yuen, S.T.3
Leung, S.Y.4
Chung, L.P.5
-
80
-
-
0030664484
-
Vascular endothelial growth factor in squamous head and neck carcinoma: Expression and prognostic significance
-
Salven P., Heikkila P., Anttonen A., Kajanti M., Joensuu H. Vascular endothelial growth factor in squamous head and neck carcinoma. expression and prognostic significance Modern Pathol. 10:1997;1128-1133.
-
(1997)
Modern Pathol.
, vol.10
, pp. 1128-1133
-
-
Salven, P.1
Heikkila, P.2
Anttonen, A.3
Kajanti, M.4
Joensuu, H.5
-
81
-
-
0031778206
-
Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
-
ElAssal O.N., Yamanoi A., Soda Y.et al. Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver. possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver Hepatology. 27:1998;1554-1562.
-
(1998)
Hepatology
, vol.27
, pp. 1554-1562
-
-
Elassal, O.N.1
Yamanoi, A.2
Soda, Y.3
-
82
-
-
0032252634
-
Vascular endothelial growth factor increased by pulmonary surgery accelerates the growth of micrometastases in metastatic lung cancer
-
Maniwa Y., Okada M., Ishii N., Kiyooka K. Vascular endothelial growth factor increased by pulmonary surgery accelerates the growth of micrometastases in metastatic lung cancer. Chest. 114:1998;1668-1675.
-
(1998)
Chest
, vol.114
, pp. 1668-1675
-
-
Maniwa, Y.1
Okada, M.2
Ishii, N.3
Kiyooka, K.4
-
83
-
-
0031878495
-
Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression
-
Matsuura A., Yamochi W., Hirata K., Kawashima S., Yokoyama M. Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression. Hypertension. 32:1998;89-95.
-
(1998)
Hypertension
, vol.32
, pp. 89-95
-
-
Matsuura, A.1
Yamochi, W.2
Hirata, K.3
Kawashima, S.4
Yokoyama, M.5
-
84
-
-
0033953487
-
Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours
-
Parliament M.B., Allalunis-Turner M.J., Franko A.J.et al. Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours. Br. J. Cancer. 82:2000;635-641.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 635-641
-
-
Parliament, M.B.1
Allalunis-Turner, M.J.2
Franko, A.J.3
-
85
-
-
0032170012
-
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker
-
Raleigh J.A., CalkinsAdams D.P., Rinker L.H.et al. Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res. 58:1998;3765-3768.
-
(1998)
Cancer Res.
, vol.58
, pp. 3765-3768
-
-
Raleigh, J.A.1
Calkinsadams, D.P.2
Rinker, L.H.3
-
86
-
-
0034114771
-
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas
-
Raleigh J.A., Chou S.C., CalkinsAdams D.P., Ballenger C.A., Novotny D.B., Varia M.A. A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas. Clin. Cancer Res. 6:2000;855-862.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 855-862
-
-
Raleigh, J.A.1
Chou, S.C.2
Calkinsadams, D.P.3
Ballenger, C.A.4
Novotny, D.B.5
Varia, M.A.6
-
87
-
-
0028105848
-
Hypoxia regulatory elements of the human vascular endothelial growth factor gene
-
Minchenko A., Salceda S., Bauer T.et al. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell. Mol. Biol. Res. 40:1994;35-39.
-
(1994)
Cell. Mol. Biol. Res.
, vol.40
, pp. 35-39
-
-
Minchenko, A.1
Salceda, S.2
Bauer, T.3
-
88
-
-
0027328476
-
Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart
-
Ladoux A., Frelin C. Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart. Biochem. Biophys. Res. Commun. 195:1993;1005-1010.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.195
, pp. 1005-1010
-
-
Ladoux, A.1
Frelin, C.2
-
89
-
-
0030806074
-
Upregulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia driven mechanisms
-
Damert A., Machein M., Breier G.et al. Upregulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia driven mechanisms. Cancer Res. 57:1997;3860-3864.
-
(1997)
Cancer Res.
, vol.57
, pp. 3860-3864
-
-
Damert, A.1
MacHein, M.2
Breier, G.3
-
90
-
-
0030044039
-
Posttranscriptional regulation of vascular endothelial growth factor by hypoxia
-
Levy A.P., Levy N.S., Goldberg M.A. Posttranscriptional regulation of vascular endothelial growth factor by hypoxia. J. Biol. Chem. 271:1996;2746-2753.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2746-2753
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
-
91
-
-
0032513043
-
Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
-
Levy N.S., Chung S.M., Furneaux H., Levy A.P. Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J. Biol. Chem. 273:1998;6417-6423.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6417-6423
-
-
Levy, N.S.1
Chung, S.M.2
Furneaux, H.3
Levy, A.P.4
-
92
-
-
0032941747
-
Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of RNA elements
-
Dibbens J.A., Miller D.L., Damert A., Risau W., Vada M.A., Goodall G.J. Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of RNA elements. Mol. Biol. Cell. 10:1999;907-919.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 907-919
-
-
Dibbens, J.A.1
Miller, D.L.2
Damert, A.3
Risau, W.4
Vada, M.A.5
Goodall, G.J.6
-
93
-
-
0031869662
-
Translation of vascular endothelial growth factor mRNA by internal ribosome entry: Implications for translation under hypoxia
-
Stein I., Itin A., Einat P., Skaliter R., Grossmann Z., Keshet E. Translation of vascular endothelial growth factor mRNA by internal ribosome entry. implications for translation under hypoxia Mol. Cell. Biol. 18:1998;3112-3119.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3112-3119
-
-
Stein, I.1
Itin, A.2
Einat, P.3
Skaliter, R.4
Grossmann, Z.5
Keshet, E.6
-
94
-
-
0032537757
-
Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription
-
Akiri G., Nahari D., Finkelstein Y., Le S.Y., ElroyStein O., Levi B.Z. Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription. Oncogene. 17:1998;227-236.
-
(1998)
Oncogene.
, vol.17
, pp. 227-236
-
-
Akiri, G.1
Nahari, D.2
Finkelstein, Y.3
Le, S.Y.4
Elroystein, O.5
Levi, B.Z.6
-
95
-
-
0032422032
-
The vascular endothelial growth factor mRNA contains an internal ribosome entry site
-
Miller D.L., Dibbens J.A., Damert A., Risau W., Vadas M.A., Goodall G.J. The vascular endothelial growth factor mRNA contains an internal ribosome entry site. FEBS. Lett. 434:1998;417-420.
-
(1998)
FEBS. Lett.
, vol.434
, pp. 417-420
-
-
Miller, D.L.1
Dibbens, J.A.2
Damert, A.3
Risau, W.4
Vadas, M.A.5
Goodall, G.J.6
-
96
-
-
0032583569
-
Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase
-
Kitazono M., Takebayashi Y., Ishitsuka K.et al. Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase. Biochem. Biophys. Res. Commun. 253:1998;797-803.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.253
, pp. 797-803
-
-
Kitazono, M.1
Takebayashi, Y.2
Ishitsuka, K.3
-
97
-
-
0031742541
-
The influence of elevated levels of platelet derived endothelial growth factor thymidine phosphorylase on tumorigenicity, tumour growth and oxygenation
-
Griffiths L., Stratford I.J. The influence of elevated levels of platelet derived endothelial growth factor thymidine phosphorylase on tumorigenicity, tumour growth and oxygenation. Int. J. Radiat. Oncol. Biol. Phys. 42:1998;877-883.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.42
, pp. 877-883
-
-
Griffiths, L.1
Stratford, I.J.2
-
98
-
-
0031045574
-
Platelet derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small cell lung cancer
-
Koukourakis M.I., Giatromanolaki A., O'Byrne K.J.et al. Platelet derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small cell lung cancer. Br. J. Cancer. 75:1997;477-481.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 477-481
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
O'Byrne, K.J.3
-
99
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial growth factor, acidic and basic fibroblast growth factor, tumour growth factor β-1, platelet derived endothelial cell growth factor, placenta growth factor and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M., LeJeune S., Scott P.A.E.et al. Expression of the angiogenic factors vascular endothelial growth factor, acidic and basic fibroblast growth factor, tumour growth factor β-1, platelet derived endothelial cell growth factor, placenta growth factor and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res. 57:1997;963-969.
-
(1997)
Cancer Res.
, vol.57
, pp. 963-969
-
-
Relf, M.1
Lejeune, S.2
Scott, P.A.E.3
-
100
-
-
0030665017
-
Nitric oxide in tumour biology and cancer therapy. Part 1: Physiological aspects
-
Tozer G.M., Everett S.A. Nitric oxide in tumour biology and cancer therapy. Part 1: physiological aspects. Clin. Oncol. 9:1997;282-293.
-
(1997)
Clin. Oncol.
, vol.9
, pp. 282-293
-
-
Tozer, G.M.1
Everett, S.A.2
-
101
-
-
0031307208
-
Nitric oxide in tumour biology and cancer therapy. Part 2: Therapeutic implications
-
Tozer G.M., Everett S.A. Nitric oxide in tumour biology and cancer therapy. Part 2: Therapeutic implications. Clin. Oncol. 9:1997;357-364.
-
(1997)
Clin. Oncol.
, vol.9
, pp. 357-364
-
-
Tozer, G.M.1
Everett, S.A.2
-
102
-
-
0342839922
-
Mechanism of production and radiosensitizing effect of nitric oxide generated by chemical donors and nitric oxide synthase
-
Verovski B., Bols B., Van den Berg D., Storme G. Mechanism of production and radiosensitizing effect of nitric oxide generated by chemical donors and nitric oxide synthase. Proc. Am. Assoc. Cancer Res. 38:1997;43.
-
(1997)
Proc. Am. Assoc. Cancer Res.
, vol.38
, pp. 43
-
-
Verovski, B.1
Bols, B.2
Van Den Berg, D.3
Storme, G.4
-
103
-
-
0031814913
-
Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices
-
Moro M.A., De-Alba J., Leza J.C.et al. Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices. Eur. J. Neurosci. 10:1998;445-456.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 445-456
-
-
Moro, M.A.1
De-Alba, J.2
Leza, J.C.3
-
104
-
-
0031888729
-
Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1
-
Palmer L.A., Semenza G.L., Stoler M.H., Johns R.A. Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1. Am. J. Physiol. 274:1998;L212-L219.
-
(1998)
Am. J. Physiol.
, vol.274
, pp. 212-L219
-
-
Palmer, L.A.1
Semenza, G.L.2
Stoler, M.H.3
Johns, R.A.4
-
105
-
-
15844405458
-
Regulation of endothelial nitric-oxide synthase during hypoxia
-
Arnet U., McMillan A., Dinerman J., Ballermann B., Lowenstein C. Regulation of endothelial nitric-oxide synthase during hypoxia. J. Biol. Chem. 271:1996;15069-15073.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15069-15073
-
-
Arnet, U.1
McMillan, A.2
Dinerman, J.3
Ballermann, B.4
Lowenstein, C.5
-
106
-
-
0033966770
-
Endothelial cell regulation of nitric oxide production during hypoxia in coronary microvessels and epicardial arteries
-
Justice J.M., Tanner M.A., Myers P.R. Endothelial cell regulation of nitric oxide production during hypoxia in coronary microvessels and epicardial arteries. J. Cell. Physiol. 182:2000;359-365.
-
(2000)
J. Cell. Physiol.
, vol.182
, pp. 359-365
-
-
Justice, J.M.1
Tanner, M.A.2
Myers, P.R.3
-
107
-
-
0028825749
-
Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen
-
Liao J.K., Zulueta J.J., Yu F-S., Peng H-B., Cote C.G., Hassoun P.M. Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen. J. Clin. Invest. 96:1995;2661-2666.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2661-2666
-
-
Liao, J.K.1
Zulueta, J.J.2
Yu, F.-S.3
Peng, H.-B.4
Cote, C.G.5
Hassoun, P.M.6
-
108
-
-
0029948575
-
Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells
-
Phelan M., Faller D. Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells. J. Cell. Physiol. 167:1996;469-476.
-
(1996)
J. Cell. Physiol.
, vol.167
, pp. 469-476
-
-
Phelan, M.1
Faller, D.2
-
110
-
-
0032891180
-
Endothelial responses to hypoxic stress
-
Faller D.V. Endothelial responses to hypoxic stress. Clin. Exp. Pharmacol. Physiol. 26:1999;74-84.
-
(1999)
Clin. Exp. Pharmacol. Physiol.
, vol.26
, pp. 74-84
-
-
Faller, D.V.1
-
111
-
-
0027533216
-
Oxygen tension regulates the nitric oxide pathway: Physiological role in penile erection
-
Kim N., Vardi Y., Padma-Nathan H., Daley J., Goldstein I., Saenz de Tejada I. Oxygen tension regulates the nitric oxide pathway. physiological role in penile erection J. Clin. Invest. 91:1993;437-442.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 437-442
-
-
Kim, N.1
Vardi, Y.2
Padma-Nathan, H.3
Daley, J.4
Goldstein, I.5
Saenz De Tejada, I.6
-
112
-
-
16944364864
-
Nitric oxide binding to the heme of neuronal nitric-oxide synthase links its activity to changes in oxygen tension
-
Abu-Soud H., Rousseau D.L., Stuehr D.J. Nitric oxide binding to the heme of neuronal nitric-oxide synthase links its activity to changes in oxygen tension. J. Biol. Chem. 271:1996;32515-32518.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32515-32518
-
-
Abu-Soud, H.1
Rousseau, D.L.2
Stuehr, D.J.3
-
113
-
-
0028215982
-
Nitric oxide synthase activity in human gynecological cancer
-
Thomsen L.L., Lawton F.G., Knowles R.G., Beesley J.E., Riveros-Moreno V., Moncada S. Nitric oxide synthase activity in human gynecological cancer. Cancer Res. 54:1994;1352-1354.
-
(1994)
Cancer Res.
, vol.54
, pp. 1352-1354
-
-
Thomsen, L.L.1
Lawton, F.G.2
Knowles, R.G.3
Beesley, J.E.4
Riveros-Moreno, V.5
Moncada, S.6
-
114
-
-
0028873889
-
Expression of nitric oxide synthase in human central nervous system tumors
-
Cobbs C.S., Brenman J.E., Aldape K.D., Bredt D.S., Israel M.A. Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res. 55:1995;727-730.
-
(1995)
Cancer Res.
, vol.55
, pp. 727-730
-
-
Cobbs, C.S.1
Brenman, J.E.2
Aldape, K.D.3
Bredt, D.S.4
Israel, M.A.5
-
115
-
-
0029024521
-
Nitric oxide synthase activity in human breast cancer
-
Thomsen L.L., Miles D.W., Happerfield L., Bobrow L.G., Knowles R.G., Moncada S. Nitric oxide synthase activity in human breast cancer. Br. J. Cancer. 72:1995;41-44.
-
(1995)
Br. J. Cancer
, vol.72
, pp. 41-44
-
-
Thomsen, L.L.1
Miles, D.W.2
Happerfield, L.3
Bobrow, L.G.4
Knowles, R.G.5
Moncada, S.6
-
116
-
-
0001635282
-
Inducible nitric oxide synthase is expressed in tumour-associated vasculature: Inhibition retards tumour growth in vivo
-
S. Moncada, M. Feelisch, R. Busse, & E.A. Higgs. London: Portland Press
-
Kennovin G.D., Hirst D.G., Stratford M.R.L., Flitney F.W. Inducible nitric oxide synthase is expressed in tumour-associated vasculature. inhibition retards tumour growth in vivo Moncada S., Feelisch M., Busse R., Higgs E.A. The Biology of Nitric Oxide 4. Enzymology, Biochemistry and Immunology. 1994;473-479 Portland Press, London.
-
(1994)
The Biology of Nitric Oxide 4. Enzymology, Biochemistry and Immunology
, pp. 473-479
-
-
Kennovin, G.D.1
Hirst, D.G.2
Stratford, M.R.L.3
Flitney, F.W.4
-
117
-
-
0029671094
-
NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in adenocarcinoma-bearing mice
-
Orucevic A., Lala P.K. NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in adenocarcinoma-bearing mice. Br. J. Cancer. 73:1996;189-196.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 189-196
-
-
Orucevic, A.1
Lala, P.K.2
-
119
-
-
0028929559
-
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
-
Xie K., Huang S., Dong Z.et al. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J. Exp. Med. 181:1995;1333-1343.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1333-1343
-
-
Xie, K.1
Huang, S.2
Dong, Z.3
-
120
-
-
0033135593
-
Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53
-
Shi Q., Huang S., Jiang W., Kutach L.S., Ananthaswamy H.N. Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53. Cancer Res. 59:1999;2072-2075.
-
(1999)
Cancer Res.
, vol.59
, pp. 2072-2075
-
-
Shi, Q.1
Huang, S.2
Jiang, W.3
Kutach, L.S.4
Ananthaswamy, H.N.5
-
121
-
-
0031954295
-
Role of nitric oxide in tumor progression: Lessons from experimental tumors
-
Lala P.K., Orucevic A. Role of nitric oxide in tumor progression. lessons from experimental tumors Cancer Metastasis Rev. 17:1998;91-106.
-
(1998)
Cancer Metastasis Rev.
, vol.17
, pp. 91-106
-
-
Lala, P.K.1
Orucevic, A.2
-
122
-
-
0028856579
-
Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo
-
Rocha M., Krüger A., Van Rooijen N., Schirrmacher V., Umansky V. Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo. Int. J. Cancer. 63:1995;405-411.
-
(1995)
Int. J. Cancer
, vol.63
, pp. 405-411
-
-
Rocha, M.1
Krüger, A.2
Van Rooijen, N.3
Schirrmacher, V.4
Umansky, V.5
-
123
-
-
84991430788
-
A novel NGF-regulated pathway involving nitric oxide, p53 and p21WAF1 controls differentiation of PC12 cells
-
Poluha W., Harrington K.S., Lachyankar M.B., Schonhoff C.M., Crosbie N.E., Ross A.H. A novel NGF-regulated pathway involving nitric oxide, p53 and p21WAF1 controls differentiation of PC12 cells. Proc. Am. Assoc. Cancer Res. 39:1997;498.
-
(1997)
Proc. Am. Assoc. Cancer Res.
, vol.39
, pp. 498
-
-
Poluha, W.1
Harrington, K.S.2
Lachyankar, M.B.3
Schonhoff, C.M.4
Crosbie, N.E.5
Ross, A.H.6
-
124
-
-
0342405086
-
Interaction of nitric oxide and p53 in tumor growth: A putative model for clonal selection of mutant p53 cells
-
Ambs S., Merriam W.G., Bennet W.P.et al. Interaction of nitric oxide and p53 in tumor growth. a putative model for clonal selection of mutant p53 cells Proc. Am. Assoc. Cancer Res. 39:1997;273.
-
(1997)
Proc. Am. Assoc. Cancer Res.
, vol.39
, pp. 273
-
-
Ambs, S.1
Merriam, W.G.2
Bennet, W.P.3
-
125
-
-
0026460303
-
Inhibitors of nitric oxide synthase selectively reduce flow in tumour-associated neovasculature
-
Andrade S.P., Hart I.R., Piper P.J. Inhibitors of nitric oxide synthase selectively reduce flow in tumour-associated neovasculature. Br. J. Pharmacol. 107:1992;1092-1095.
-
(1992)
Br. J. Pharmacol.
, vol.107
, pp. 1092-1095
-
-
Andrade, S.P.1
Hart, I.R.2
Piper, P.J.3
-
126
-
-
0029061096
-
Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma
-
Meyer R.E., Shan S., DeAngelo J.et al. Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma. Br. J. Cancer. 71:1995;1169-1174.
-
(1995)
Br. J. Cancer
, vol.71
, pp. 1169-1174
-
-
Meyer, R.E.1
Shan, S.2
Deangelo, J.3
-
127
-
-
0031018039
-
Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine
-
Tozer G.M., Prise V.E., Chaplin D.J. Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. Cancer Res. 57:1997;948-955.
-
(1997)
Cancer Res.
, vol.57
, pp. 948-955
-
-
Tozer, G.M.1
Prise, V.E.2
Chaplin, D.J.3
-
128
-
-
0028659788
-
Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine
-
Wood P.J., Sansom J.M., Butler S.A.et al. Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine. Cancer Res. 54:1994;6458-6463.
-
(1994)
Cancer Res.
, vol.54
, pp. 6458-6463
-
-
Wood, P.J.1
Sansom, J.M.2
Butler, S.A.3
-
129
-
-
0032716059
-
Impaired wound healing and angiogenesis in eNOS-deficient mice
-
Lee P.C., Salyapongse A.N., Bragdon G.A.et al. Impaired wound healing and angiogenesis in eNOS-deficient mice. Am. J. Physiol. 277:1999;H1600-H1608.
-
(1999)
Am. J. Physiol.
, vol.277
, pp. 1600-H1608
-
-
Lee, P.C.1
Salyapongse, A.N.2
Bragdon, G.A.3
-
130
-
-
0032850637
-
Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor-induced angiogenesis in mammary tumors
-
Jadeski L.C., Lala P.K. Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor-induced angiogenesis in mammary tumors. Am. J. Pathol. 155:1999;1381-1390.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1381-1390
-
-
Jadeski, L.C.1
Lala, P.K.2
-
131
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
Papapetropoulos A., Garcia-Cardena G., Madri J.A., Sessa W.C. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J. Clin. Invest. 100:1997;3131-3139.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.C.4
-
132
-
-
0031008458
-
Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis
-
Ziche M., Morbidelli L., Choudhuri R.et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J. Clin. Invest. 99:1997;2625-2634.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2625-2634
-
-
Ziche, M.1
Morbidelli, L.2
Choudhuri, R.3
-
133
-
-
0033529650
-
Vascular endothelial growth factor-induced endothelial cell migration and proliferation depend on a nitric oxide-mediated decrease in protein kinase C delta activity
-
Shizukuda Y., Tang S., Yokota R., Ware J.A. Vascular endothelial growth factor-induced endothelial cell migration and proliferation depend on a nitric oxide-mediated decrease in protein kinase C delta activity. Circ. Res. 85:1999;247-256.
-
(1999)
Circ. Res.
, vol.85
, pp. 247-256
-
-
Shizukuda, Y.1
Tang, S.2
Yokota, R.3
Ware, J.A.4
-
135
-
-
0033609922
-
Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-SRC
-
He H., Venema V.J., Gu X., Venema R.C., Marrero M.B., Caldwell R.B. Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-SRC. J. Biol. Chem. 274:1999;25130-25135.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25130-25135
-
-
He, H.1
Venema, V.J.2
Gu, X.3
Venema, R.C.4
Marrero, M.B.5
Caldwell, R.B.6
-
136
-
-
0033975850
-
Hypoxia response element of the human vascular endothelial growth factor gene mediates transcription regulated by nitric oxide: Control of hypoxia-inducible factor-1 activity by nitric oxide
-
Kimura H., Weisz A., Kurashima Y.et al. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcription regulated by nitric oxide. control of hypoxia-inducible factor-1 activity by nitric oxide Blood. 95:2000;189-197.
-
(2000)
Blood
, vol.95
, pp. 189-197
-
-
Kimura, H.1
Weisz, A.2
Kurashima, Y.3
-
137
-
-
0032511014
-
Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′enhancer
-
Liu Y.X., Christou H., Morita T., Laughner E., Semenza G.L., Kourembanas S. Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′enhancer. J. Biol. Chem. 273:1998;15257-15262.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15257-15262
-
-
Liu, Y.X.1
Christou, H.2
Morita, T.3
Laughner, E.4
Semenza, G.L.5
Kourembanas, S.6
-
138
-
-
0029880726
-
Differential regulation of cardiac heme oxygenase-1 and vascular endothelial growth factor mRNA expressions by hemin, heavy metals, heat shock and anoxia
-
Eyssen-Hernandez R., Ladoux A., Frelin C. Differential regulation of cardiac heme oxygenase-1 and vascular endothelial growth factor mRNA expressions by hemin, heavy metals, heat shock and anoxia. FEBS. Lett. 382:1996;229-233.
-
(1996)
FEBS. Lett.
, vol.382
, pp. 229-233
-
-
Eyssen-Hernandez, R.1
Ladoux, A.2
Frelin, C.3
-
139
-
-
0030065052
-
NO-mediated activation of heme oxygenase: Endogenous cytoprotection against oxidative stress to endothelium
-
Motterlini R., Foresti R., Intaglietta M., Winslow R.M. NO-mediated activation of heme oxygenase. endogenous cytoprotection against oxidative stress to endothelium Am. J. Physiol. 270:1996;H107-H114.
-
(1996)
Am. J. Physiol.
, vol.270
, pp. 107-H114
-
-
Motterlini, R.1
Foresti, R.2
Intaglietta, M.3
Winslow, R.M.4
-
140
-
-
0030056221
-
Expression of heme oxygenase isozyme mRNAs in the human brain and the induction of heme oxygenase-1 by nitric oxide donors
-
Takahashi K., Hara E., Suzuki H., Sasano H., Shibara S. Expression of heme oxygenase isozyme mRNAs in the human brain and the induction of heme oxygenase-1 by nitric oxide donors. J. Neurochem. 67:1996;482-489.
-
(1996)
J. Neurochem.
, vol.67
, pp. 482-489
-
-
Takahashi, K.1
Hara, E.2
Suzuki, H.3
Sasano, H.4
Shibara, S.5
-
141
-
-
0031770617
-
The comparative effects of the NOS inhibitor, Nw-nitro-L-arginine, and the haemoxygenase inhibitor, zinc protoporphyrin IX, on tumour blood flow
-
Tozer G.M., Prise V.E., Motterlini R., Poole B.A., Wilson J., Chaplin D.J. The comparative effects of the NOS inhibitor, Nw-nitro-L-arginine, and the haemoxygenase inhibitor, zinc protoporphyrin IX, on tumour blood flow. Int. J. Radiat. Oncol. Biol. Phys. 42:1998;849-853.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.42
, pp. 849-853
-
-
Tozer, G.M.1
Prise, V.E.2
Motterlini, R.3
Poole, B.A.4
Wilson, J.5
Chaplin, D.J.6
-
142
-
-
0030873998
-
An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumour cells
-
Jang A., Hill R.P. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumour cells. Clin. Exp. Metastasis. 15:1997;469-483.
-
(1997)
Clin. Exp. Metastasis
, vol.15
, pp. 469-483
-
-
Jang, A.1
Hill, R.P.2
-
143
-
-
0030866613
-
Hypoxia stimulates proximal tubular cell matrix production via a TGFβ-independent mechanism
-
Orphanides C., Fine L.G., Norman J.T. Hypoxia stimulates proximal tubular cell matrix production via a TGFβ-independent mechanism. Kidney Int. 52:1997;637-647.
-
(1997)
Kidney Int.
, vol.52
, pp. 637-647
-
-
Orphanides, C.1
Fine, L.G.2
Norman, J.T.3
-
144
-
-
0033002459
-
Significance of membrane type 1 matrix metalloproteinase expression in breast cancer
-
Ishigaki S., Toi M., Ueno T.et al. Significance of membrane type 1 matrix metalloproteinase expression in breast cancer. Jpn. J. Cancer Res. 90:1999;516-522.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 516-522
-
-
Ishigaki, S.1
Toi, M.2
Ueno, T.3
-
145
-
-
0032570760
-
Studies of type IV collagenase regulation by hypoxia
-
Himelstein B.P., Koch C.J. Studies of type IV collagenase regulation by hypoxia. Cancer Lett. 124:1998;127-133.
-
(1998)
Cancer Lett.
, vol.124
, pp. 127-133
-
-
Himelstein, B.P.1
Koch, C.J.2
-
146
-
-
0033521864
-
Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression
-
Graham C.H., Forsdike J., Fitzgerald C.J., Macdonald Goodfellow S. Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression. Int. J. Cancer. 80:1999;617-623.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 617-623
-
-
Graham, C.H.1
Forsdike, J.2
Fitzgerald, C.J.3
MacDonald Goodfellow, S.4
-
147
-
-
0033869074
-
Gene delivery to hypoxic cells in vitro
-
in press
-
Dachs GU, Coralli C, Hart SL, Tozer GM. Gene delivery to hypoxic cells in vitro. Br J Cancer 2000, 83, in press.
-
(2000)
Br J Cancer
, pp. 83
-
-
Dachs, G.U.1
Coralli, C.2
Hart, S.L.3
Tozer, G.M.4
-
148
-
-
0030968939
-
Targeting gene expression to hypoxic tumour cells
-
Dachs G.U., Patterson A.V., Firth J.D.et al. Targeting gene expression to hypoxic tumour cells. Nature Med. 3:1997;515-520.
-
(1997)
Nature Med.
, vol.3
, pp. 515-520
-
-
Dachs, G.U.1
Patterson, A.V.2
Firth, J.D.3
-
149
-
-
0032866070
-
An adenoviral vector regulated by hypoxia for the treatment of ischemic disease and cancer
-
Binley K., Iqball S., Kingsman A., Kingsman S., Naylor S. An adenoviral vector regulated by hypoxia for the treatment of ischemic disease and cancer. Gene Ther. 6:1999;1721-1727.
-
(1999)
Gene Ther.
, vol.6
, pp. 1721-1727
-
-
Binley, K.1
Iqball, S.2
Kingsman, A.3
Kingsman, S.4
Naylor, S.5
-
150
-
-
0033198913
-
Characterization of physiologically regulated vectors for the treatment of ischemic disease
-
Boast K., Binley K., Iqball S.et al. Characterization of physiologically regulated vectors for the treatment of ischemic disease. Human Gene Ther. 10:1999;2197-2208.
-
(1999)
Human Gene Ther.
, vol.10
, pp. 2197-2208
-
-
Boast, K.1
Binley, K.2
Iqball, S.3
-
151
-
-
0034017489
-
Development of a hypoxia-responsive vector for tumour-specific gene therapy
-
Shibata T., Giaccia A.J., Brown J.M. Development of a hypoxia-responsive vector for tumour-specific gene therapy. Gene Ther. 7:2000;493-498.
-
(2000)
Gene Ther.
, vol.7
, pp. 493-498
-
-
Shibata, T.1
Giaccia, A.J.2
Brown, J.M.3
-
152
-
-
0029609610
-
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
-
Bridgewater J.A., Springer C.J., Knox R.J., Minton N.P., Michael N.P., Collins M.K. Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954. Eur. J. Cancer. 31A:1995;2326-2370.
-
(1995)
Eur. J. Cancer
, vol.31
, pp. 2326-2370
-
-
Bridgewater, J.A.1
Springer, C.J.2
Knox, R.J.3
Minton, N.P.4
Michael, N.P.5
Collins, M.K.6
-
153
-
-
0032975737
-
Molecular chemotherapy for breast cancer
-
Patterson A.V., Harris A.L. Molecular chemotherapy for breast cancer. Drugs Aging. 14:1999;75-90.
-
(1999)
Drugs Aging
, vol.14
, pp. 75-90
-
-
Patterson, A.V.1
Harris, A.L.2
-
154
-
-
0000089970
-
Development of an enzyme prodrug combination for gene therapy of cancer
-
Greco O., Dachs G.U., Wardman P., Folkes L.K., Chaplin D.J. Development of an enzyme prodrug combination for gene therapy of cancer. Proc. Am. Assoc. Cancer Res. 40:1999;478.
-
(1999)
Proc. Am. Assoc. Cancer Res.
, vol.40
, pp. 478
-
-
Greco, O.1
Dachs, G.U.2
Wardman, P.3
Folkes, L.K.4
Chaplin, D.J.5
-
155
-
-
0040187605
-
Utilising horseradish peroxidase for hypoxia-induced gene therapy
-
Greco O., Tozer G.M., Dachs G.U. Utilising horseradish peroxidase for hypoxia-induced gene therapy. Proc. Am. Assoc. Cancer Res. 41:2000;733.
-
(2000)
Proc. Am. Assoc. Cancer Res.
, vol.41
, pp. 733
-
-
Greco, O.1
Tozer, G.M.2
Dachs, G.U.3
-
156
-
-
0033998433
-
The macrophage- A novel system to deliver gene therapy to pathological hypoxia
-
Griffiths L., Binley K., Iqball S.et al. The macrophage- a novel system to deliver gene therapy to pathological hypoxia. Gene Ther. 7:2000;255-262.
-
(2000)
Gene Ther.
, vol.7
, pp. 255-262
-
-
Griffiths, L.1
Binley, K.2
Iqball, S.3
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