Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

Cancer Research

Volumn 56, Issue 5, 1996, Pages 941-943

  Brizel, David M ^a,d   Scully, Sean P ^c   Harrelson, John M ^c   Layfield, Lester J ^b   Bean, Joseph M ^a   Prosnitz, Leonard R ^a   Dewhirst, Mark W ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY   (United States)

^c DUKE CANCER INSTITUTE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CANCER THERAPY; CLINICAL ARTICLE; HUMAN; LUNG METASTASIS; METASTASIS; PRIORITY JOURNAL; SOFT TISSUE SARCOMA; TISSUE OXYGENATION; TREATMENT OUTCOME; TUMOR BLOOD FLOW;

CELL HYPOXIA; HUMANS; NEOPLASM METASTASIS; PREDICTIVE VALUE OF TESTS; SARCOMA; SOFT TISSUE NEOPLASMS;

EID: 0030022252     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Gray, L. H., Conger, A D , Ebert, M., Hornsey, S., and Scott, O. C A. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy Br J Radiol , 26, 638-648, 1953.
2. Gatenby, R. A., Kessler, H. B., Rosenblum, J. S., Coia, L. R., Moldofsky, P. J., Hartz, W. H., and Broder, G. J Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy Int. J Radiat. Oncol Biol. Phys., 14: 831-838, 1988.
3. 2 predicts survival in advanced cancer of the uterine cervix Radiother. Oncol., 26, 45-50, 1993.
4. Leopold, K. A., Harrelson, J., Prosnitz, L., Samulski, T. V., Dewhirst, M. W., and Oleson, J. R. Preoperative hyperthermia and radiation for soft tissue sarcomas: advantage of two vs one hyperthermia treatments per week. Int J. Radiat. Oncol. Biol. Phys., 16, 107-115, 1989
5. Brizel, D M., Rosner, G. Harrelson, J., Prosnitz, L. R., and Dewhirst, M. W. Pretreatment oxygenation profiles of human soft tissue sarcomas. Int. J. Radiat Oncol. Biol. Phys., 30: 635-642, 1994.
6. Brizel, D. M., Rosner, G. and Dewhirst, M W. An evaluation of the patterns and variability of tumor oxygenation on human soft tissue sarcomas, cervical carcinomas. and lymph node metastases. Int. J Radiat. Oncol. Biol Phys., 32: 1121-1125, 1995
7. Takeshita, N., Tanaka, Y , and Matsuda, T. Evaluation of CT images, tumor response and prognosis after thermoradiotherapy for deep seated tumors Int. J. Hyperthermia, 9, 1-17, 1993.
8. Burger, P. C., Dubois, P. J , Schold, S. C , Smith, K. R., Odom, G L., Crafts, D. C., and Giangaspero, F. Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme J Neurosurg., 58, 159-169, 1983.
9. Nordsmark, M., Bentzen, S. M., and Overgaard, J. Measurement of human tumor oxygenation status by a polarographic needle electrode. An analysis of inter- and intratumor heterogeneity. Acta Oncol , 33: 383-389, 1994
10. Kaplan, E. L , and Meier, P. Nonparametric estimation from incomplete observations J. Am. Stat. Assoc., 55: 457-481, 1958
11. Schwickert, G., Walenta, S , Sundfor, K., Rofstad, E. K. and Mueller-Kleiser, W Correlation of high lactate levels in human cervical cancer with the incidence of metastasis. Cancer Res., 55: 4757-4759, 1995.
12. Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., and Giaccia, A. J. Hypoxia mediated selection of cells with diminished apoptotic potential in solid tumors. Nature (Lond ), 379: 88-91, 1996.
13. Young, S. D., Marshall, R S., and Hill, R. P. Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc. Natl. Acad Sci. USA, 85: 9533-9537, 1988.
14. Levy, A. P., Levy, N. S., Wegner, S., and Goldberg, M. A Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol Chem., 270; 13333-13340, 1995
15. Shweiki, D , Neeman, M., Itin, A., and Keshet, E. Induction of vascular endothelial growth factor expression by hypoxia and glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc. Natl. Acad Sci. USA, 92: 768-772, 1995.
16. Weidner, N., Semple, J. P., Welch, W. R., and Folkman, J. Tumor angiogenesis and metastasis-correlation in invasive breast cancer. N. Engl. J. Med., 324: 1-8, 1991.
17. Weidner, N., Carroll, P. R , Flax, J , Blumenfeld, W , and Folkman, J. Tumor angiogenesis correlates with metastasis in invasive prostate cancer. Am. J. Pathol., 143; 401-409, 1993.
18. Weiner, T M , Liu, E T , Craven, R. J , and Cance, W. G. Expression of focal adhesion kinase gene and invasive cancer. Lancet, 342: 1024-1025, 1993.
19. Dorudi, S , Sheffield, J. P., Poulsom, R., Northover, J. M., and Hart, I R. E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am. J. Pathol., 142: 981-986, 1993.
20. Umbas, R , Isaacs, W. B., Bringuier, P P , Schaafsma, H. E., Karthaus, H. F , Oosterhof, G. O , Debruyne, F. M , and Schalken. J. A. Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer. Cancer Res., 54 3929-3933, 1994.
21. Scheumman, G. F., Hoang-Vu, C., Cetin, Y., Gimm, O., Behrends, J., von Wasielewski, R., Georgii, A , Birchmeier, W , vonZurMuhlen, A., and Dralle, H. Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas. J. Clin Endocrinol. & Metab., 80: 2168-2172, 1995
22. Huth, J. F., and Eilber, F R Patters of metastatic spread following resection of extremity soft tissue sarcoma and strategies for treatment. Semin. Surg. Oncol., 4: 20-26, 1988
23. Scully, S P , Oleson, J R., Leopold, K. A., Samulski, T. V , Dodge, R., and Harrelson, J. M Clinical outcome after neoadjuvant thermoradiotherapy in high grade soft tissue sarcomas. J. Surg Oncol , 57: 143-151, 1994.
24. Bramwell, V., Rousse, J., Steward, W., Santoro, A., Schraffordt-Koops, H., Buesa, J., Ruka, W , Priario, J. Wagener, T., Burgers, M , Unnik, J. V , Contesso, G., Thomas, D., Glabbeke, M., Markham, D., and Pinedo, H. Adjuvant CYVADIC chemotherapy for adult soft tissue sarcoma - reduced local recurrence but no improvement in survival: a study of the European Organization for the Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J Clin Oncol., 12: 1137-11149, 1994.
25. Rosenberg, S. A., Tepper, J., Glatstein, E., Costa, J., Young, R., Baker, A , Brennan, M. F., Demoss, E. V., Seipp, C., Sindelar, W. F., Sugarbaker, P. and Wesley, R. Prospective randomized evaluation of adjuvant chemotherapy in adults with soft tissue sarcomas of the extremities. Cancer (Phila.), 52: 424-434, 1983.