Genetic disruption of host nitric oxide synthase II gene impairs melanoma-induced angiogenesis and suppresses pleural effusion

International Journal of Cancer

Volumn 91, Issue 5, 2001, Pages 607-611

  Wang, Bailiang ^a,b   Xiong, Qinghua ^a,b   Shi, Qian ^a   Tan, Daniel ^a   Le, Xiangdong ^a,b   Xie, Keping ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Angiogenesis; Metastasis melanoma; Nitric oxide; Pleural effusion

Indexed keywords

GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CYTOKINE PRODUCTION; GENE DISRUPTION; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; MELANOMA CELL; METASTASIS; MOUSE; NONHUMAN; PLEURA EFFUSION; PRIORITY JOURNAL;

ANIMALS; ENDOTHELIAL GROWTH FACTORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, P53; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; LYMPHOKINES; MELANOMA; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PLEURAL EFFUSION; RNA, MESSENGER; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035284055     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1109>3.0.CO;2-D     Document Type: Article

References (34)

1. Nitric oxide as a secretory product of mammalian cells
2. The L-arginine-nitric oxide pathway
3. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
4. Role of nitric oxide in angiogenesis and microcirculation in tumors
5. The role of nitric oxide (NO) in the carcinogenic process
6. The multifaceted roles of nitric oxide in cancer
7. Therapy of cancer metastasis by activation of the inducible nitric oxide synthase
8. Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
9. Human colorectal adenocarcinoma cells: Differential nitric oxide synthesis determines their ability to aggregate platelets
10. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells
11. Direct correlation between nitric oxide synthase II inducibility and metastatic ability of UV-2237 murine fibrosarcoma cells carrying mutant p53
12. Macrophage cytotoxicity: Role for L-arginine deaminase activity and amino nitrogen to nitrate
13. Nitric oxide synthase activity in human breast cancer
14. Expression of nitric oxide synthase in human central nervous system tumors
15. Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism
16. NO at work
17. p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells
18. Roles of nitric oxide in tumor growth
19. Vascular endothelial growth factor is a secreted angiogenic mitogen
20. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
21. Growth rate and chromosome number of tumor cell lines with different metastatic potential
22. The selection and characterization of an invasive variant of the B16 melanoma
23. Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation
24. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages
25. Influence of nitric oxide synthase II gene disruption on tumor growth and metastasis
26. Angiogenesis research: From laboratory to clinic
27. Serum concentrations of vascular endothelial growth factor and nitrite as an estimate of in vivo nitric oxide in patients with gastric cancer
28. Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair
29. Reciprocal relation between VEGF and NO in the regulation of endothelial integrity
30. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries
31. Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium
32. VEGF induces NO-dependent hyperpermeability in coronary venules
33. Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide
34. Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells