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Volumn 30, Issue 4, 2002, Pages 355-362

Atypical kinetic profiles in drug metabolism reactions

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; BENZYLOXYRESORUFIN; CELECOXIB; CYTOCHROME P450; DAPSONE; DEXTROMETHORPHAN; DIAZEPAM; DRUG; ESTRADIOL; ETHOXYRESORUFIN; FLUOXETINE; HALOTHANE; PARACETAMOL; PROGESTERONE; QUINIDINE; TENOXICAM; TESTOSTERONE; TRIAZOLAM; UNCLASSIFIED DRUG;

EID: 0036201594     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.4.355     Document Type: Short Survey
Times cited : (248)

References (62)
  • 10
    • 0032499691 scopus 로고    scopus 로고
    • Analysis of human cytochrome P450 3A4 cooperativity: Construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6636-6641
    • Harlow, G.R.1    Halpert, J.R.2
  • 34
    • 0031466149 scopus 로고    scopus 로고
    • Nonspecific binding to microsomes: Impact on scale-up of in vitro intrinsic clearance to hepatic clearance as assessed through examination of warfarin, imipramine, and propranolol
    • (1997) Drug Metab Dispos , vol.25 , pp. 1359-1369
    • Obach, R.S.1
  • 35
    • 0035078792 scopus 로고    scopus 로고
    • Metabolism of levo-α-acetylmethadol (LAAM) by human liver cytochrome P450: Involvement of CYP3A4 characterized by atypical kinetics with two binding sites
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 410-422
    • Oda, Y.1    Kharasch, E.D.2
  • 59
    • 0032968065 scopus 로고    scopus 로고
    • Sigmoidal kinetics of CYP3A substrates: An approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 58-65
    • Witherow, L.E.1    Houston, J.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.