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Journal of Biological Chemistry

Volumn 276, Issue 3, 2001, Pages 2256-2262

A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4

(6) Shou, Magang a Dai, Renke b,d Cui, Dan a Korzekwa, Kenneth R c Baillie, Thomas A a Rushmore, Thomas H a

a MERCK RESEARCH LABORATORIES (United States)

b NATIONAL CANCER INSTITUTE (United States)

c Camitro Corporation (United States)

d BRISTOL MYERS SQUIBB (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 3A4; DRUG METABOLITE; LOSARTAN;

ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME BINDING; HUMAN; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL;

BENZOFLAVONES; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; KINETICS; LOSARTAN; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; SUBSTRATE SPECIFICITY;

EID: 0035910579 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M008799200 Document Type: Article

Times cited : (118)

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