메뉴 건너뛰기




Volumn 29, Issue 6, 2001, Pages 877-886

In vitro stimulation of warfarin metabolism by quinidine: Increases in the formation of 4′- and 10-hydroxywarfarin

Author keywords

[No Author keywords available]

Indexed keywords

10 HYDROXYWARFARIN; 4' HYDROXYWARFARIN; QUINIDINE; UNCLASSIFIED DRUG; WARFARIN;

EID: 0035015062     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (84)

References (45)
  • 2
    • 0027237647 scopus 로고
    • Evaluation of the pharmacokinetic and pharmacodynamic interaction between quinidine and nifedipine
    • Bowles SK, Reeves RA, Cardozo L and Edwards DJ (1993) Evaluation of the pharmacokinetic and pharmacodynamic interaction between quinidine and nifedipine. J Clin Pharmacol 33: 727-731.
    • (1993) J Clin Pharmacol , vol.33 , pp. 727-731
    • Bowles, S.K.1    Reeves, R.A.2    Cardozo, L.3    Edwards, D.J.4
  • 3
    • 0019364430 scopus 로고
    • Activation and inhibition of benzo(a)pyrene and aflatoxin b1 metabolism in human liver microsomes by naturally occurring flavonoids
    • Buening MK, Chang RL, Huang M-T, Fortner JG, Wood AW and Conney AH (1981) Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids. Cancer Res 41:67-72.
    • (1981) Cancer Res , vol.41 , pp. 67-72
    • Buening, M.K.1    Chang, R.L.2    Huang, M.-T.3    Fortner, J.G.4    Wood, A.W.5    Conney, A.H.6
  • 4
    • 0014125542 scopus 로고
    • Pharmacological implications of microsomal enzyme induction
    • Conney AH (1967) Pharmacological implications of microsomal enzyme induction. Pharmacol Rev 19:317-366.
    • (1967) Pharmacol Rev , vol.19 , pp. 317-366
    • Conney, A.H.1
  • 5
    • 0034108229 scopus 로고    scopus 로고
    • Dual role of human cytochrome P450 3A4 residue PHE 304 in substrate specificity and cooperjtivity
    • Domanski TL, He Y-A, Harlow GR and Halpert JR (2000) Dual role of human cytochrome P450 3A4 residue PHE 304 in substrate specificity and cooperjtivity. J Pharmacol Exp Ther 293:585-591.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 585-591
    • Domanski, T.L.1    He, Y.-A.2    Harlow, G.R.3    Halpert, J.R.4
  • 6
    • 0032822383 scopus 로고    scopus 로고
    • Three-dimensional-quantitative structure activity relationship analysis of cytochrome P-450 3A4 substrates
    • Ekins S, Bravi G, Wikel JH and Wrighton SA (1999) Three-dimensional-quantitative structure activity relationship analysis of cytochrome P-450 3A4 substrates. J Pharmacol Exp Ther 291:424-433.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 424-433
    • Ekins, S.1    Bravi, G.2    Wikel, J.H.3    Wrighton, S.A.4
  • 7
    • 0029041949 scopus 로고
    • Aiming for safe anticoagulation
    • Fihn SD (1995) Aiming for safe anticoagulation. N Eng J Med 333:54-55.
    • (1995) N Eng J Med , vol.333 , pp. 54-55
    • Fihn, S.D.1
  • 9
    • 0030627336 scopus 로고    scopus 로고
    • Role of cytochrome P450 enzymes in drug-drug interactions
    • Guengerich FP (1997) Role of cytochrome P450 enzymes in drug-drug interactions. Adv Pharmacol 43:7-35.
    • (1997) Adv Pharmacol , vol.43 , pp. 7-35
    • Guengerich, F.P.1
  • 10
    • 0022467917 scopus 로고
    • Oxidation of quinidine by human liver cytochrome P450
    • Guengerich FP, Muller-Enoch D and Blair IA (1986) Oxidation of quinidine by human liver cytochrome P450. Mol Pharmacol 30:287-295.
    • (1986) Mol Pharmacol , vol.30 , pp. 287-295
    • Guengerich, F.P.1    Muller-Enoch, D.2    Blair, I.A.3
  • 11
  • 12
    • 0029886356 scopus 로고    scopus 로고
    • Clinical important drug interactions with anticoagulants
    • Harder S and Thurmann P (1996) Clinical important drug interactions with anticoagulants. Clin Pharmacokinet 30:416-444.
    • (1996) Clin Pharmacokinet , vol.30 , pp. 416-444
    • Harder, S.1    Thurmann, P.2
  • 13
    • 0032499691 scopus 로고    scopus 로고
    • Analysis of human cytochrome P450 3A4 cooperativity construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics
    • Harlow GR and Halpert JR (1998) Analysis of human cytochrome P450 3A4 cooperativity construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics. Proc Natl Acad Sci USA 95:6636-6641.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6636-6641
    • Harlow, G.R.1    Halpert, J.R.2
  • 15
    • 0034705191 scopus 로고    scopus 로고
    • Elucidation of distinct ligand binding sites for cytochrome P450 3A4
    • Hosea NA, Miller GP and Guengerich FP (2000) Elucidation of distinct ligand binding sites for cytochrome P450 3A4. Biochemistry 39:5929-5939.
    • (2000) Biochemistry , vol.39 , pp. 5929-5939
    • Hosea, N.A.1    Miller, G.P.2    Guengerich, F.P.3
  • 16
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • Kaminsky LS and Zhang Z-Y (1997) Human P450 metabolism of warfarin. Pharmacol Ther 73:67-74.
    • (1997) Pharmacol Ther , vol.73 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.-Y.2
  • 18
    • 0014263920 scopus 로고
    • Quinidine-induced hypoprothrombinemic hemorrhage in patients on chronic warfarin therapy
    • Koch-Weser J (1968) Quinidine-induced hypoprothrombinemic hemorrhage in patients on chronic warfarin therapy. Ann Intern Med 68:511-517.
    • (1968) Ann Intern Med , vol.68 , pp. 511-517
    • Koch-Weser, J.1
  • 19
    • 0015208247 scopus 로고
    • Drug interactions with coumarin anticoagulants
    • Koch-Weser J and Sellers EM (1971) Drug interactions with coumarin anticoagulants. N Eng J Med 285:547-558.
    • (1971) N Eng J Med , vol.285 , pp. 547-558
    • Koch-Weser, J.1    Sellers, E.M.2
  • 21
    • 0031022331 scopus 로고    scopus 로고
    • Differential mechanism of cytochrome P450 inhibition and activation by α-naphthoflavone
    • Koley AP, Buters JTM, Robinson RC, Markowitz A and Friedman FK (1997) Differential mechanism of cytochrome P450 inhibition and activation by α-naphthoflavone. J Biol Chem 272:3149-3152.
    • (1997) J Biol Chem , vol.272 , pp. 3149-3152
    • Koley, A.P.1    Buters, J.T.M.2    Robinson, R.C.3    Markowitz, A.4    Friedman, F.K.5
  • 22
    • 0000574406 scopus 로고    scopus 로고
    • Evaluation of atypical cytochrome P450 kinetics with two-substrate models: Evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites
    • Korzekwa KR, Krishnamachary N, Shou M, Ogai A, Parise RA, Rettie AE, Gonzalez FJ and Tracy TS (1998) Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites. Biochemistry 37:4137-4147.
    • (1998) Biochemistry , vol.37 , pp. 4137-4147
    • Korzekwa, K.R.1    Krishnamachary, N.2    Shou, M.3    Ogai, A.4    Parise, R.A.5    Rettie, A.E.6    Gonzalez, F.J.7    Tracy, T.S.8
  • 23
    • 0026092176 scopus 로고
    • Metabolic enantiomeric interactions: The inhibition of human (S)-warfarin-7-hydroxylase by (R)-warfarin
    • Kunze K, Eddy AC, Gibaldi M and Trager WF (1991) Metabolic enantiomeric interactions: the inhibition of human (S)-warfarin-7-hydroxylase by (R)-warfarin. Chirality 3:24-29.
    • (1991) Chirality , vol.3 , pp. 24-29
    • Kunze, K.1    Eddy, A.C.2    Gibaldi, M.3    Trager, W.F.4
  • 24
    • 0019955123 scopus 로고
    • In vivo activation of zoxazolamine metabolism by flaxone
    • Lasker JM, Huang M-T and Conney AH (1982) In vivo activation of zoxazolamine metabolism by flaxone. Science (Wash DC) 216:1419-1421.
    • (1982) Science (Wash DC) , vol.216 , pp. 1419-1421
    • Lasker, J.M.1    Huang, M.-T.2    Conney, A.H.3
  • 25
    • 0033045179 scopus 로고    scopus 로고
    • Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5′-methylhydroxylation by quinidine and hydroquinidine in vitro
    • Ludwig E, Schmid J, Beschke K and Ebner T (1999) Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5′-methylhydroxylation by quinidine and hydroquinidine in vitro. J Pharmacol Exp Ther 290:1-8.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1-8
    • Ludwig, E.1    Schmid, J.2    Beschke, K.3    Ebner, T.4
  • 26
    • 0000169232 scopus 로고
    • An algorithm for least-squares estimation of nonlinear parameters
    • Marquardt DW (1963) An algorithm for least-squares estimation of nonlinear parameters. J Soc Indust Appl Math 11:431-441.
    • (1963) J Soc Indust Appl Math , vol.11 , pp. 431-441
    • Marquardt, D.W.1
  • 27
    • 0032723284 scopus 로고    scopus 로고
    • Role of a potent inhibitory monoclonal antibody to cytochrome P450 3A4 in assessment of human drug metabolism
    • Mei Q, Tang C, Assang C, Slaughter D, Rodrigues DA, Rushmore TH and Shou M (1999) Role of a potent inhibitory monoclonal antibody to cytochrome P450 3A4 in assessment of human drug metabolism. J Pharmacol Exp Ther 291:749-759.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 749-759
    • Mei, Q.1    Tang, C.2    Assang, C.3    Slaughter, D.4    Rodrigues, D.A.5    Rushmore, T.H.6    Shou, M.7
  • 29
    • 0016695234 scopus 로고
    • Interaction of chronic daily warfarin therapy and rifampin
    • O'Reilly RA (1975) Interaction of chronic daily warfarin therapy and rifampin. Ann Intern Med 83:506-508.
    • (1975) Ann Intern Med , vol.83 , pp. 506-508
    • O'Reilly, R.A.1
  • 31
    • 0031023651 scopus 로고    scopus 로고
    • Toxicity of allyl alcohol in primary cultures of freshly isolated and cryopreserved hepatocytes maintained on hydrated collagen gels
    • Pang J-M, Zaleski J and Kauffman FC (1997) Toxicity of allyl alcohol in primary cultures of freshly isolated and cryopreserved hepatocytes maintained on hydrated collagen gels. Toxicol Appl Pharmacol 142:87-94.
    • (1997) Toxicol Appl Pharmacol , vol.142 , pp. 87-94
    • Pang, J.-M.1    Zaleski, J.2    Kauffman, F.C.3
  • 32
    • 0026349867 scopus 로고
    • Isolation of P450 enzymes from human liver
    • Raucy JL and Lasker JM (1991) Isolation of P450 enzymes from human liver. Methods Enzymol 206:557-587.
    • (1991) Methods Enzymol , vol.206 , pp. 557-587
    • Raucy, J.L.1    Lasker, J.M.2
  • 34
    • 0034013033 scopus 로고    scopus 로고
    • Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochrome P450
    • Sai Y, Dai R, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV and Shou M (2000) Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochrome P450. Xenobiotica 30:327-343.
    • (2000) Xenobiotica , vol.30 , pp. 327-343
    • Sai, Y.1    Dai, R.2    Yang, T.J.3    Krausz, K.W.4    Gonzalez, F.J.5    Gelboin, H.V.6    Shou, M.7
  • 36
  • 37
    • 0020541851 scopus 로고
    • Evidence that disopyramide does not interact with warfarin
    • Sylven C and Anderson P (1983) Evidence that disopyramide does not interact with warfarin. Br Med J 286:1181-1182.
    • (1983) Br Med J , vol.286 , pp. 1181-1182
    • Sylven, C.1    Anderson, P.2
  • 39
    • 0032417493 scopus 로고    scopus 로고
    • Molecular basis of P450 inhibition and activation: Implications for drug development and drug therapy
    • Szklarz GD and Halpert JR (1998) Molecular basis of P450 inhibition and activation: implications for drug development and drug therapy. Drug Metab Dispos 26:1379-1184.
    • (1998) Drug Metab Dispos , vol.26 , pp. 1379-11184
    • Szklarz, G.D.1    Halpert, J.R.2
  • 41
    • 0027162246 scopus 로고
    • Determination of the interaction of 3S-hydroxy-10,11-dihydroquinidine on the pharmacokinetics and pharmacodynamics of warfarin
    • Trenk D, Mohrke W, Warth L and Jahnchen E (1993) Determination of the interaction of 3S-hydroxy-10,11-dihydroquinidine on the pharmacokinetics and pharmacodynamics of warfarin. Arzneim-Forsch 43:836-841.
    • (1993) Arzneim-Forsch , vol.43 , pp. 836-841
    • Trenk, D.1    Mohrke, W.2    Warth, L.3    Jahnchen, E.4
  • 42
  • 44
    • 0026750647 scopus 로고
    • The human hepatic cytochrome P450 involved in drug metabolism
    • Wrighton SA and Stevens JC (1992) The human hepatic cytochrome P450 involved in drug metabolism. Crit Rev Toxicol 22:1-21.
    • (1992) Crit Rev Toxicol , vol.22 , pp. 1-21
    • Wrighton, S.A.1    Stevens, J.C.2
  • 45
    • 0030700392 scopus 로고    scopus 로고
    • Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R-and S-warfarin enantiomers
    • Yamazaki H and Shimada T (1997) Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R-and S-warfarin enantiomers. Biochem Pharmacol 54:1195-1203.
    • (1997) Biochem Pharmacol , vol.54 , pp. 1195-1203
    • Yamazaki, H.1    Shimada, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.