Mechanism of cytochrome P450 activation by caffeine and 7,8- benzoflavone in rat liver microsomes

Drug Metabolism and Disposition

Volumn 25, Issue 10, 1997, Pages 1150-1156

  Lee, Caroline A ^b   Manyike, Peter T ^b   Thummel, Kenneth E ^b   Nelson, Sidney D ^b   Slattery, John T ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; CAFFEINE; CUMENE HYDROPEROXIDE; CYTOCHROME B5; CYTOCHROME P450; ENZYME ANTIBODY; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON TRANSPORT; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME PURIFICATION; LIVER MICROSOME; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BENZOFLAVONES; BENZOQUINONES; CAFFEINE; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; ELECTRON TRANSPORT; ENZYME ACTIVATION; IMINES; MALE; MICROSOMES, LIVER; NADH, NADPH OXIDOREDUCTASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030802791     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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