Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4: Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5

Journal of Biological Chemistry

Volumn 271, Issue 44, 1996, Pages 27438-27444

  Yamazaki, Hiroshi ^a   Johnson, William W ^b   Ueng, Yune Fang ^c   Shimada, Tsutomu ^a   Guengerich, F Peter ^c  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CATALASE; CYTOCHROME B5; CYTOCHROME C; CYTOCHROME P450; HEME; HEMOGLOBIN; NIFEDIPINE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; TESTOSTERONE;

ANIMAL TISSUE; ARTICLE; CATALYSIS; ELECTRON; ELECTRON TRANSPORT; HYDROXYLATION; NONHUMAN; OXIDATION; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN BINDING; RABBIT; STEADY STATE;

ANIMALS; APOPROTEINS; CATALYSIS; CATTLE; CLONING, MOLECULAR; CYTOCHROME B GROUP; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B; CYTOCHROMES B5; ELECTRON TRANSPORT; ESCHERICHIA COLI; HUMANS; KINETICS; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; RABBITS; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY; TESTOSTERONE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0029926494     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.44.27438     Document Type: Article

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