메뉴 건너뛰기




Volumn 28, Issue 5, 2000, Pages 560-566

In vitro glucuronidation using human liver microsomes and the pore- forming peptide alamethicin

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXYCOUMARIN; ALAMETHICIN; CYTOCHROME P450; ESTRADIOL; GLUCURONOSYLTRANSFERASE; MORPHINE; PARACETAMOL;

EID: 0034009448     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (322)

References (41)
  • 1
    • 0027173475 scopus 로고
    • Intraluminal calcium of the liver endoplasmic reticulum stimulates the glucuronidation of p-nitrophenol
    • Banhegyi G, Bellomo G, Fulceri R, Mandl J and Benedetti A (1993) Intraluminal calcium of the liver endoplasmic reticulum stimulates the glucuronidation of p-nitrophenol. Biochem J 292:99-104.
    • (1993) Biochem J , vol.292 , pp. 99-104
    • Banhegyi, G.1    Bellomo, G.2    Fulceri, R.3    Mandl, J.4    Benedetti, A.5
  • 3
    • 0038845974 scopus 로고    scopus 로고
    • Demonstration of a metabolically active glucose-6-phosphate pool in the lumen of liver microsomal vesicles
    • Banhegyi G, Marcolongo P, Fulceri R, Hinds C, Burchell A and Benedetti A (1997) Demonstration of a metabolically active glucose-6-phosphate pool in the lumen of liver microsomal vesicles. J Biol Chem 272:13584-13590.
    • (1997) J Biol Chem , vol.272 , pp. 13584-13590
    • Banhegyi, G.1    Marcolongo, P.2    Fulceri, R.3    Hinds, C.4    Burchell, A.5    Benedetti, A.6
  • 4
    • 0028796027 scopus 로고
    • Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles
    • Berg CL, Radominska A, Lester R and Gollan JL (1995) Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles. Gastroenterology 108:183-192.
    • (1995) Gastroenterology , vol.108 , pp. 183-192
    • Berg, C.L.1    Radominska, A.2    Lester, R.3    Gollan, J.L.4
  • 6
    • 0029913593 scopus 로고    scopus 로고
    • Uridine diphosphoxylose enhances hepatic microsomal UDP-glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane
    • Bossuyt X and Blanckaert N (1996) Uridine diphosphoxylose enhances hepatic microsomal UDP-glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane. Biochem J 315:189-193.
    • (1996) Biochem J , vol.315 , pp. 189-193
    • Bossuyt, X.1    Blanckaert, N.2
  • 8
    • 0032789591 scopus 로고    scopus 로고
    • Kinetic studies of hepatocytes UDP-glucuronosyltransferase: Evidence of an allosteric enzyme
    • Bruni S and Chang TMS (1999) Kinetic studies of hepatocytes UDP-glucuronosyltransferase: Evidence of an allosteric enzyme. Art Cells Blood Subs and Immob Biotech 27:343-356.
    • (1999) Art Cells Blood Subs and Immob Biotech , vol.27 , pp. 343-356
    • Bruni, S.1    Chang, T.M.S.2
  • 9
    • 0028875109 scopus 로고
    • Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
    • Burchell B, Brierley CH and Rance D (1995) Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation. Life Sci 57:1819-1831.
    • (1995) Life Sci , vol.57 , pp. 1819-1831
    • Burchell, B.1    Brierley, C.H.2    Rance, D.3
  • 12
    • 0032432731 scopus 로고    scopus 로고
    • High throughput screening for inhibition of cytochrome P450 metabolism
    • Crespi CL, Miller VP and Penman BW (1998) High throughput screening for inhibition of cytochrome P450 metabolism. Med Chem Res 8:457-471.
    • (1998) Med Chem Res , vol.8 , pp. 457-471
    • Crespi, C.L.1    Miller, V.P.2    Penman, B.W.3
  • 13
    • 0032997374 scopus 로고    scopus 로고
    • Advances in in vitro drug metabolism screening
    • Eddershaw PJ and Dickins M (1999) Advances in in vitro drug metabolism screening. Pharm Sci Technol Today 2:13-19.
    • (1999) Pharm Sci Technol Today , vol.2 , pp. 13-19
    • Eddershaw, P.J.1    Dickins, M.2
  • 15
    • 0031974584 scopus 로고    scopus 로고
    • A universal radiochemical high-performance liquid chromatographic assay for the determination of UDP-glucuronosyltransferase activity
    • Ethell BT, Anderson GD, Beaumont K, Rance DJ and Burchell B (1998) A universal radiochemical high-performance liquid Chromatographic assay for the determination of UDP-glucuronosyltransferase activity. Anal Biochem 255:142-147.
    • (1998) Anal Biochem , vol.255 , pp. 142-147
    • Ethell, B.T.1    Anderson, G.D.2    Beaumont, K.3    Rance, D.J.4    Burchell, B.5
  • 16
    • 0028223564 scopus 로고
    • Evidence for the intraluminal positioning of p-nitrophenol UDP-glucuronosyltransferase activity in rat liver microsomes
    • Fulceri R, Banhegyi G, Gamberucci A, Giunti R, Mandl J and Benedetti A (1994) Evidence for the intraluminal positioning of p-nitrophenol UDP-glucuronosyltransferase activity in rat liver microsomes. Arch Biochem Biophvs 309:43-46.
    • (1994) Arch Biochem Biophvs , vol.309 , pp. 43-46
    • Fulceri, R.1    Banhegyi, G.2    Gamberucci, A.3    Giunti, R.4    Mandl, J.5    Benedetti, A.6
  • 19
    • 0029959846 scopus 로고    scopus 로고
    • Mechanism of alamethicin insertion into lipid bilayers
    • He K, Ludtke SJ, Heller WT and Huang HW (1996) Mechanism of alamethicin insertion into lipid bilayers. Biophys J 71:2669-2679.
    • (1996) Biophys J , vol.71 , pp. 2669-2679
    • He, K.1    Ludtke, S.J.2    Heller, W.T.3    Huang, H.W.4
  • 20
    • 0026654417 scopus 로고
    • Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity
    • Imaoka S, Imai Y, Shimada T and Funae Y (1992) Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity. Biochemistry 31:6063-6069.
    • (1992) Biochemistry , vol.31 , pp. 6063-6069
    • Imaoka, S.1    Imai, Y.2    Shimada, T.3    Funae, Y.4
  • 21
    • 0031723235 scopus 로고    scopus 로고
    • Prediction of pharmacokinetic alterations caused by drug-drug interactions: Metabolic interaction in the liver
    • Ito K, Iwatsubo T, Kanamitsu S, Ueda K, Suzuki H and Sugiyama Y (1998) Prediction of pharmacokinetic alterations caused by drug-drug interactions: Metabolic interaction in the liver. Pharmacol Rev 50:387-411.
    • (1998) Pharmacol Rev , vol.50 , pp. 387-411
    • Ito, K.1    Iwatsubo, T.2    Kanamitsu, S.3    Ueda, K.4    Suzuki, H.5    Sugiyama, Y.6
  • 22
    • 0033564554 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase
    • Jedlitschky G, Cassidy AJ, Sales M, Pratt N and Burchell B (1999) Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase. Biochem J 340:837-843.
    • (1999) Biochem J , vol.340 , pp. 837-843
    • Jedlitschky, G.1    Cassidy, A.J.2    Sales, M.3    Pratt, N.4    Burchell, B.5
  • 24
    • 0000574406 scopus 로고    scopus 로고
    • Evaluation of atypical cytochrome P450 kinetics with two-substrate models: Evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites
    • Korzekwa KR, Krishnamachary N, Shou M, Ogai A, Parise RA, Rettie AE, Gonzalez FJ and Tracy TS (1998) Evaluation of atypical cytochrome P450 kinetics with two-substrate models: Evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites. Biochemistry 37:4137-4147.
    • (1998) Biochemistry , vol.37 , pp. 4137-4147
    • Korzekwa, K.R.1    Krishnamachary, N.2    Shou, M.3    Ogai, A.4    Parise, R.A.5    Rettie, A.E.6    Gonzalez, F.J.7    Tracy, T.S.8
  • 25
    • 0026602510 scopus 로고
    • Optimal detergent activation of rat liver microsomal UDP-glucuronosyltransferases toward morphine and 1-naphthol: Contribution to induction and latency studies
    • Lett E, Kriszt W, de Sandro V, Ducrotoy G and Richert L (1992) Optimal detergent activation of rat liver microsomal UDP-glucuronosyltransferases toward morphine and 1-naphthol: Contribution to induction and latency studies. Biochem Pharmacol 43:1649-1653.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1649-1653
    • Lett, E.1    Kriszt, W.2    De Sandro, V.3    Ducrotoy, G.4    Richert, L.5
  • 27
    • 0002051568 scopus 로고
    • The UDP-glucuronosyltransferase multigene family
    • Hodgson E, Bend JR and Philpot RM eds Toxicology Communications Inc., Raleigh, NC
    • Mackenzie PI (1995) The UDP-glucuronosyltransferase multigene family, in Rev Biochem Toxicol (Hodgson E, Bend JR and Philpot RM eds) 11: 29-72. Toxicology Communications Inc., Raleigh, NC.
    • (1995) Rev Biochem Toxicol , vol.11 , pp. 29-72
    • Mackenzie, P.I.1
  • 29
    • 0030778114 scopus 로고    scopus 로고
    • Structure and function of uridine diphosphate glucuronosyltransferases
    • Meech R and Mackenzie PI (1997) Structure and function of uridine diphosphate glucuronosyltransferases. Clin Exp Pharmacol Physiol 24:907-915.
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , pp. 907-915
    • Meech, R.1    Mackenzie, P.I.2
  • 30
  • 31
    • 0343550267 scopus 로고    scopus 로고
    • Heterologous expression of human UDP-glucuronosyl transferases
    • Patten CJ, Leakey JAE, Frame LT and Crespi CL (1998) Heterologous expression of human UDP-glucuronosyl transferases. ISSX Proc 13:197.
    • (1998) ISSX Proc , vol.13 , pp. 197
    • Patten, C.J.1    Leakey, J.A.E.2    Frame, L.T.3    Crespi, C.L.4
  • 33
    • 0028114740 scopus 로고
    • Use of in vitro human metabolism studies in drug development
    • Rodrigues AD (1994) Use of in vitro human metabolism studies in drug development. Biochem Pharmacol 48:2147-2156.
    • (1994) Biochem Pharmacol , vol.48 , pp. 2147-2156
    • Rodrigues, A.D.1
  • 35
    • 0027991904 scopus 로고
    • Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
    • Senafi SB, Clarke DJ and Burchell B (1994) Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem J 303:233-240.
    • (1994) Biochem J , vol.303 , pp. 233-240
    • Senafi, S.B.1    Clarke, D.J.2    Burchell, B.3
  • 36
    • 0028814798 scopus 로고
    • 2+ in permeabilized smooth muscle cells with use of furaptra
    • Cell Physiol 38
    • 2+ in permeabilized smooth muscle cells with use of furaptra. Am J Physiol 269 (Cell Physiol 38): C698-C705.
    • (1995) Am J Physiol , vol.269
    • Sugiyama, T.1    Goldman, W.F.2
  • 37
    • 0031808472 scopus 로고    scopus 로고
    • Glucuronidation of 3′-azido-3′-deoxythymidine (zidovudine) by human liver microsomes-relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid
    • Trapnell CB, Klecker RW, Jamis-Dow C and Collins JM (1998) Glucuronidation of 3′-azido-3′-deoxythymidine (zidovudine) by human liver microsomes-relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid. Antimicrob Agents Chemother 42:1592-1596.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1592-1596
    • Trapnell, C.B.1    Klecker, R.W.2    Jamis-Dow, C.3    Collins, J.M.4
  • 38
    • 0016174577 scopus 로고
    • Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes
    • van der Hoeven TA and Coon MJ (1974) Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. J Biol them 249:6302-6310.
    • (1974) J Biol Them , vol.249 , pp. 6302-6310
    • Van Der Hoeven, T.A.1    Coon, M.J.2
  • 39
    • 0023909231 scopus 로고
    • Topology and regulation of bilirubin UDP-glucuronyltransferase in sealed native microsomes from rat liver
    • Vanstapel F and Blanckaert N (1988) Topology and regulation of bilirubin UDP-glucuronyltransferase in sealed native microsomes from rat liver. Arch Biochem Biophys 263:216-225.
    • (1988) Arch Biochem Biophys , vol.263 , pp. 216-225
    • Vanstapel, F.1    Blanckaert, N.2
  • 40
    • 0032079546 scopus 로고    scopus 로고
    • Golgi localization and functional expression of human uridine diphosphatase
    • Wang T-F and Guidotti G (1998) Golgi localization and functional expression of human uridine diphosphatase. J Biol Chem 273:11392-11399.
    • (1998) J Biol Chem , vol.273 , pp. 11392-11399
    • Wang, T.-F.1    Guidotti, G.2
  • 41
    • 0015818579 scopus 로고
    • Effects of metals on the properties of hepatic microsomal uridine diphosphate glucuronyltransferase
    • Zakim D, Goldenberg J and Vessey DA (1973) Effects of metals on the properties of hepatic microsomal uridine diphosphate glucuronyltransferase. Biochemistry 12:4068-4074.
    • (1973) Biochemistry , vol.12 , pp. 4068-4074
    • Zakim, D.1    Goldenberg, J.2    Vessey, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.