Substrate inhibition kinetics for cytochrome P450-catalyzed reactions

Drug Metabolism and Disposition

Volumn 29, Issue 4 I, 2001, Pages 368-374

  Lin, Yuh ^a   Lu, Ping ^a   Tang, Cuyue ^a   Mei, Qin ^a   Sandig, Grit ^a   Rodrigues, A David ^a   Rushmore, Thomas H ^a   Shou, Magang ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORZOXAZONE; CYTOCHROME P450; DEXTROMETHORPHAN; DIAZEPAM; ESTRONE; ETHOXYRESORUFIN; FLURBIPROFEN; MEPHENYTOIN; PACLITAXEL; PHENACETIN; PROGESTERONE; RECOMBINANT PROTEIN; RESORUFIN DERIVATIVE; TESTOSTERONE;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SUBSTRATE; HUMAN; INHIBITION KINETICS; MOLECULAR INTERACTION; NONHUMAN; PREDICTION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; KINETICS; OXAZINES; PROGESTERONE; PYRAZOLES; SUBSTRATE SPECIFICITY; SULFONAMIDES;

EID: 0035059509     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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