-
1
-
-
0028238769
-
Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
-
Snider WD. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell. 1994; 77:627-638.
-
(1994)
Cell
, vol.77
, pp. 627-638
-
-
Snider, W.D.1
-
2
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim RW. Cell death during development of the nervous system. Ann Rev Neurosci. 1991;14:453-501.
-
(1991)
Ann Rev Neurosci
, vol.14
, pp. 453-501
-
-
Oppenheim, R.W.1
-
3
-
-
0028874195
-
Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF
-
Oppenheim RW, Houenou LJ, Johnson JE, et al. Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature. 1995;373:344-346.
-
(1995)
Nature
, vol.373
, pp. 344-346
-
-
Oppenheim, R.W.1
Houenou, L.J.2
Johnson, J.E.3
-
4
-
-
0027373764
-
Programmed cell death and the control of cell survival: Lessons from the nervous system
-
Raff MC, Barres BA, Burne JF, et al. Programmed cell death and the control of cell survival: lessons from the nervous system. Science. 1993;262:695-700.
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
-
5
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
Green DR. Apoptotic pathways: the roads to ruin. Cell. 1998;94: 695-698.
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
7
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell. 1997;88:355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
8
-
-
0032525332
-
Purification and characterization of a Mg2+-dependent endonuclease (AN34) from etoposide-treated human leukemia HL-60 cells undergoing apoptosis
-
Yoshida A, Pourquier P, Pommier Y. Purification and characterization of a Mg2+-dependent endonuclease (AN34) from etoposide-treated human leukemia HL-60 cells undergoing apoptosis. Cancer Res. 1998;58:2576-2582.
-
(1998)
Cancer Res
, vol.58
, pp. 2576-2582
-
-
Yoshida, A.1
Pourquier, P.2
Pommier, Y.3
-
9
-
-
0032567430
-
Isolation and characterization of NUC70, a cytoplasmic, hematopoietic apoptotic endonuclease
-
Urbano A, McCaffrey R, Foss F. Isolation and characterization of NUC70, a cytoplasmic, hematopoietic apoptotic endonuclease. J Biol Chem. 1998;273:34820-34827.
-
(1998)
J Biol Chem
, vol.273
, pp. 34820-34827
-
-
Urbano, A.1
McCaffrey, R.2
Foss, F.3
-
10
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari M, Sakahira H, Yokoyama H, et al. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 1998;391:43-50.
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
-
11
-
-
0032560073
-
CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45
-
Halenbeck R, MacDonald H, Roulston A, et al. CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45. Curr Biol. 1998;8:537-540.
-
(1998)
Curr Biol
, vol.8
, pp. 537-540
-
-
Halenbeck, R.1
MacDonald, H.2
Roulston, A.3
-
12
-
-
0032482949
-
Molecular cloning and characterization of human caspase-activated DNase
-
Mukae N, Enari M, Sakahira H, et al. Molecular cloning and characterization of human caspase-activated DNase. Proc Natl Acad Sci USA. 1998;95:9123-9128.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9123-9128
-
-
Mukae, N.1
Enari, M.2
Sakahira, H.3
-
13
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature. 1998; 391:96-99.
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
14
-
-
0032582539
-
Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis
-
Tang D, Kidd VJ. Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis. J Biol Chem. 1998; 273:28549-28552.
-
(1998)
J Biol Chem
, vol.273
, pp. 28549-28552
-
-
Tang, D.1
Kidd, V.J.2
-
15
-
-
0032529915
-
ICAD/DFF regulator of apoptotic nuclease is nuclear
-
Samejima K, Earnshaw WC. ICAD/DFF regulator of apoptotic nuclease is nuclear. Exp Cell Res. 1998;243:453-459.
-
(1998)
Exp Cell Res
, vol.243
, pp. 453-459
-
-
Samejima, K.1
Earnshaw, W.C.2
-
16
-
-
15644384377
-
Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution
-
Samejima K, Tone S, Kottke TJ, et al. Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution. J Cell Biol. 1998;143:225-239.
-
(1998)
J Cell Biol
, vol.143
, pp. 225-239
-
-
Samejima, K.1
Tone, S.2
Kottke, T.J.3
-
17
-
-
0030047274
-
Very delayed infarction after mild focal cerebral ischemia: A role for apoptosis?
-
Du C, Hu R, Csernansky CA, et al. Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis? J Cereb Blood Flow Metab. 1996;16:195-201.
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 195-201
-
-
Du, C.1
Hu, R.2
Csernansky, C.A.3
-
18
-
-
0028843644
-
Neuronal apoptosis: Current understanding of molecular mechanisms and potential role in ischemic brain injury
-
Johnson EM Jr, Greenlund LJ, Akins PT, Hsu CY. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury. J Neurotrauma. 1995;12: 843-852.
-
(1995)
J Neurotrauma
, vol.12
, pp. 843-852
-
-
Johnson E.M., Jr.1
Greenlund, L.J.2
Akins, P.T.3
Hsu, C.Y.4
-
19
-
-
0030273118
-
Ischemia-induced neuronal apoptosis
-
Choi DW. Ischemia-induced neuronal apoptosis. Curr Opin Neurobiol. 1996;6:667-672.
-
(1996)
Curr Opin Neurobiol
, vol.6
, pp. 667-672
-
-
Choi, D.W.1
-
20
-
-
0029614765
-
Neural apoptosis
-
Bredesen DE. Neural apoptosis. Ann Neurol. 1995;38:839-851.
-
(1995)
Ann Neurol
, vol.38
, pp. 839-851
-
-
Bredesen, D.E.1
-
21
-
-
0032575694
-
Stroke-damaged neurons may commit cellular suicide
-
Barinaga M. Stroke-damaged neurons may commit cellular suicide. Science. 1998;281:1302-1303.
-
(1998)
Science
, vol.281
, pp. 1302-1303
-
-
Barinaga, M.1
-
22
-
-
0030884358
-
Apoptosis and protein expression after focal cerebral ischemia in rat
-
Li Y, Chopp M, Powers C, Jiang N. Apoptosis and protein expression after focal cerebral ischemia in rat. Brain Res. 1997;765:301-312.
-
(1997)
Brain Res
, vol.765
, pp. 301-312
-
-
Li, Y.1
Chopp, M.2
Powers, C.3
Jiang, N.4
-
23
-
-
0032918137
-
Caspases as treatment targets in stroke and neurodegenerative diseases
-
Schulz JB, Weller M, Moskowitz MA. Caspases as treatment targets in stroke and neurodegenerative diseases. Ann Neurol. 1999; 45:421-429.
-
(1999)
Ann Neurol
, vol.45
, pp. 421-429
-
-
Schulz, J.B.1
Weller, M.2
Moskowitz, M.A.3
-
24
-
-
0002204915
-
Definition and incidence of apoptosis: An historical perspective
-
: Tomei LD, Cope FO, eds. Plainview, NY: Cold Spring Harbor Laboratory Press
-
Kerr JFR, Harmon BV. Definition and incidence of apoptosis: an historical perspective. In: Tomei LD, Cope FO, eds. Apoptosis: The Molecular Basis of Cell Death. Plainview, NY: Cold Spring Harbor Laboratory Press; 1991:5-29.
-
(1991)
Apoptosis: The Molecular Basis of Cell Death
, pp. 5-29
-
-
Kerr, J.F.R.1
Harmon, B.V.2
-
25
-
-
0025732732
-
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli
-
Lennon SV, Martin SJ, Cotter TG. Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Prolif. 1991;24:203-214.
-
(1991)
Cell Prolif
, vol.24
, pp. 203-214
-
-
Lennon, S.V.1
Martin, S.J.2
Cotter, T.G.3
-
26
-
-
0029563461
-
Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus
-
Troost D, Aten J, Morsink F, de Jong JM. Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus. Neuropathol Appl Neurobiol. 1995;21:498-504.
-
(1995)
Neuropathol Appl Neurobiol
, vol.21
, pp. 498-504
-
-
Troost, D.1
Aten, J.2
Morsink, F.3
De Jong, J.M.4
-
27
-
-
0029787513
-
Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons
-
Mu X, He J, Anderson DW, et al. Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons. Ann Neurol. 1996;40:379-386.
-
(1996)
Ann Neurol
, vol.40
, pp. 379-386
-
-
Mu, X.1
He, J.2
Anderson, D.W.3
-
28
-
-
0029066687
-
Apoptosis in ALS is not restricted to motorneurons. Bcl-2 expression is increased in post-central cortex, adjacent to the affected motor cortex
-
Troost D, Aten J, Morsink F, de Jong JM. Apoptosis in ALS is not restricted to motorneurons. Bcl-2 expression is increased in post-central cortex, adjacent to the affected motor cortex. J Neurol Sci. 1995;129(suppl):79-80.
-
(1995)
J Neurol Sci
, vol.129
, Issue.SUPPL.
, pp. 79-80
-
-
Troost, D.1
Aten, J.2
Morsink, F.3
De Jong, J.M.4
-
29
-
-
0028915976
-
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: Studies in yeast and neural cells
-
Rabizadeh S, Gralla EB, Borchelt DR, et al. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proc Natl Acad Sci USA. 1995;92:3024-3028.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3024-3028
-
-
Rabizadeh, S.1
Gralla, E.B.2
Borchelt, D.R.3
-
30
-
-
0030777650
-
Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS
-
Durham HD, Roy J, Dong L, Figlewicz DA. Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS. J Neuropathol Exp Neurol. 1997;56:523-530.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 523-530
-
-
Durham, H.D.1
Roy, J.2
Dong, L.3
Figlewicz, D.A.4
-
31
-
-
0030831352
-
Mutant superoxide dismutase-1 -linked familial amyotrophic lateral sclerosis: Molecular mechanisms of neuronal death and protection
-
Ghadge GD, Lee JP, Bindokas VP, et al. Mutant superoxide dismutase-1 -linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection. J Neurosci. 1997; 17:8756-8766.
-
(1997)
J Neurosci
, vol.17
, pp. 8756-8766
-
-
Ghadge, G.D.1
Lee, J.P.2
Bindokas, V.P.3
-
32
-
-
0032430185
-
Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
-
Pasinelli P, Borchelt DR, Houseweart MK, et al. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci USA. 1998;95:15763-15768.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15763-15768
-
-
Pasinelli, P.1
Borchelt, D.R.2
Houseweart, M.K.3
-
33
-
-
0030756459
-
Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Kostic V, Jackson-Lewis V, de Bilbao F, et al. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science. 1997;277:559-562.
-
(1997)
Science
, vol.277
, pp. 559-562
-
-
Kostic, V.1
Jackson-Lewis, V.2
De Bilbao, F.3
-
34
-
-
8044252166
-
Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
-
Friedlander RM, Gagliardini V, Hara H, et al. Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med. 1997;185:933-940.
-
(1997)
J Exp Med
, vol.185
, pp. 933-940
-
-
Friedlander, R.M.1
Gagliardini, V.2
Hara, H.3
-
35
-
-
0030255620
-
A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis
-
Bryson HM, Fulton B, Benfield P. Riluzole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis. Drugs. 1996;52:549-563.
-
(1996)
Drugs
, vol.52
, pp. 549-563
-
-
Bryson, H.M.1
Fulton, B.2
Benfield, P.3
Riluzole4
-
36
-
-
0030927075
-
Glutamate, excitotoxicity and amyotrophic lateral sclerosis
-
Shaw PJ, Ince PG. Glutamate, excitotoxicity and amyotrophic lateral sclerosis. J Neurol. 1997;244:S3-S14.
-
(1997)
J Neurol
, vol.244
-
-
Shaw, P.J.1
Ince, P.G.2
-
37
-
-
0029753270
-
The pharmacology and mechanism of action of riluzole
-
Doble A. The pharmacology and mechanism of action of riluzole. Neurology. 1996;47(suppl 4):S233-S241.
-
(1996)
Neurology
, vol.47
, Issue.4 SUPPL.
-
-
Doble, A.1
-
38
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney ME, Cutting FB, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol. 1996;39:147-157.
-
(1996)
Ann Neurol
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
-
39
-
-
0030240057
-
Amyotrophic lateral sclerosis and vitamin E
-
Keane JR. Amyotrophic lateral sclerosis and vitamin E. Ann Neurol. 1996;40:480.
-
(1996)
Ann Neurol
, vol.40
, pp. 480
-
-
Keane, J.R.1
-
40
-
-
0031010921
-
Lou Gehrig and amyotrophic lateral sclerosis. Is vitamin E to be revisited?
-
Reider CR, Paulson GW. Lou Gehrig and amyotrophic lateral sclerosis. Is vitamin E to be revisited? Arch Neurol. 1997;54:527-528.
-
(1997)
Arch Neurol
, vol.54
, pp. 527-528
-
-
Reider, C.R.1
Paulson, G.W.2
-
41
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy N, Mahadevan MS, McLean M, et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell. 1995;80:167-178.
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
-
42
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
Liston P, Roy N, Tamai K, et al. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature. 1996;379:349-353.
-
(1996)
Nature
, vol.379
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
-
43
-
-
0029943383
-
Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: Homozygous NAIP deletion in a sporadic case
-
Jackson M, Morrison KE, Al-Chalabi A, et al. Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: homozygous NAIP deletion in a sporadic case. Ann Neurol. 1996;39:796-800.
-
(1996)
Ann Neurol
, vol.39
, pp. 796-800
-
-
Jackson, M.1
Morrison, K.E.2
Al-Chalabi, A.3
-
44
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
Mochizuki H, Goto K, Mori H, Mizuno Y. Histochemical detection of apoptosis in Parkinson's disease. J Neurol Sci. 1996;137: 120-123.
-
(1996)
J Neurol Sci
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
45
-
-
0031036896
-
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease
-
Anglade P, Vyas S, Javoy-Agid F, et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histol Histopathol. 1997;12:25-31.
-
(1997)
Histol Histopathol
, vol.12
, pp. 25-31
-
-
Anglade, P.1
Vyas, S.2
Javoy-Agid, F.3
-
46
-
-
0031696403
-
A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
-
Tatton NA, Maclean-Fraser A, Tatton WG, et al. A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol. 1998;44(suppl 1):S142-S148.
-
(1998)
Ann Neurol
, vol.44
, Issue.1 SUPPL.
-
-
Tatton, N.A.1
Maclean-Fraser, A.2
Tatton, W.G.3
-
47
-
-
0031930771
-
Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease
-
Banati RB, Daniel SE, Blunt SB. Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease. Mov Disord. 1998;13:221-227.
-
(1998)
Mov Disord
, vol.13
, pp. 221-227
-
-
Banati, R.B.1
Daniel, S.E.2
Blunt, S.B.3
-
48
-
-
0029040355
-
In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes
-
Dragunow M, Faull RL, Lawlor P, et al. In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes. Neuroreport. 1995;6:1053-1057.
-
(1995)
Neuroreport
, vol.6
, pp. 1053-1057
-
-
Dragunow, M.1
Faull, R.L.2
Lawlor, P.3
-
49
-
-
1842297607
-
On the question of apoptosis in the parkinsonian substantia nigra
-
Kosel S, Egensperger R, von Eitzen U, et al. On the question of apoptosis in the parkinsonian substantia nigra. Acta Neuropathol (Berl). 1997;93:105-108.
-
(1997)
Acta Neuropathol (Berl)
, vol.93
, pp. 105-108
-
-
Kosel, S.1
Egensperger, R.2
Von Eitzen, U.3
-
50
-
-
0031898760
-
Programmed cell death and Parkinson's disease
-
Burke RE. Programmed cell death and Parkinson's disease. Mov Disord. 1998;13:17-23.
-
(1998)
Mov Disord
, vol.13
, pp. 17-23
-
-
Burke, R.E.1
-
51
-
-
0031668930
-
Programmed cell death: Does it play a role in Parkinson's disease?
-
Burke RE, Kholodilov NG. Programmed cell death: does it play a role in Parkinson's disease? Ann Neurol. 1998;44:S126-S133.
-
(1998)
Ann Neurol
, vol.44
-
-
Burke, R.E.1
Kholodilov, N.G.2
-
52
-
-
0031558778
-
Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: Studies on Parkinson's and incidental Lewy body disease
-
Marshall KA, Daniel SE, Cairns N, et al. Upregulation of the anti-apoptotic protein Bcl-2 may be an early event in neurodegeneration: studies on Parkinson's and incidental Lewy body disease. Biochem Biophys Res Commun. 1997;240:84-87.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 84-87
-
-
Marshall, K.A.1
Daniel, S.E.2
Cairns, N.3
-
53
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
-
Tatton NA, Kish SJ. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience. 1997; 77:1037-1048.
-
(1997)
Neuroscience
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
54
-
-
0026345867
-
Apoptosis, and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons
-
Dipasquale B, Marini AM, Youle RJ. Apoptosis, and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons. Biodiem Biophys Res Commun. 1991;181:1442-1448.
-
(1991)
Biodiem Biophys Res Commun
, vol.181
, pp. 1442-1448
-
-
Dipasquale, B.1
Marini, A.M.2
Youle, R.J.3
-
55
-
-
0029051317
-
Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease
-
Walkinshaw G, Waters CM. Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease. J Clin Invest. 1995;95:2458-2464.
-
(1995)
J Clin Invest
, vol.95
, pp. 2458-2464
-
-
Walkinshaw, G.1
Waters, C.M.2
-
56
-
-
0031023430
-
Levodopa induces apoptosis in cultured neuronal cells - A possible accelerator of nigrostriatal degeneration in Parkinson's disease?
-
Ziv I, Zilkha-Falb R, Offen D, et al. Levodopa induces apoptosis in cultured neuronal cells - a possible accelerator of nigrostriatal degeneration in Parkinson's disease? Mov Disord. 1997;12:17-23.
-
(1997)
Mov Disord
, vol.12
, pp. 17-23
-
-
Ziv, I.1
Zilkha-Falb, R.2
Offen, D.3
-
57
-
-
0031839755
-
Levodopa neurotoxicity: Experimental studies versus clinical relevance
-
Jenner PG, Brin MF. Levodopa neurotoxicity: experimental studies versus clinical relevance. Neurology. 1998;50(suppl 6):S39-S48.
-
(1998)
Neurology
, vol.50
, Issue.6 SUPPL.
-
-
Jenner, P.G.1
Brin, M.F.2
-
58
-
-
0030300164
-
(-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase
-
Tatton WG, Wadia JS, Ju WY, et al. (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. J Neural Transm. 1996;48(suppl):45-59.
-
(1996)
J Neural Transm
, vol.48
, Issue.SUPPL.
, pp. 45-59
-
-
Tatton, W.G.1
Wadia, J.S.2
Ju, W.Y.3
-
59
-
-
0032489392
-
Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466, and R-(-)-deprenyl
-
Kragten E, Lalande I, Zimmermann K, et al. Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466, and R-(-)-deprenyl. J Biol Chem. 1998; 273:5821-5828.
-
(1998)
J Biol Chem
, vol.273
, pp. 5821-5828
-
-
Kragten, E.1
Lalande, I.2
Zimmermann, K.3
-
60
-
-
0032573597
-
Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments
-
El-Agnaf OM, Jakes R, Curran MD, et al. Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments. FEBS Lett. 1998;440:71-75.
-
(1998)
FEBS Lett
, vol.440
, pp. 71-75
-
-
El-Agnaf, O.M.1
Jakes, R.2
Curran, M.D.3
-
61
-
-
0029086807
-
DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions
-
Thomas LB, Gates DJ, Richfield EK, et al. DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions. Exp Neurol. 1995;133:265-272.
-
(1995)
Exp Neurol
, vol.133
, pp. 265-272
-
-
Thomas, L.B.1
Gates, D.J.2
Richfield, E.K.3
-
62
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
Zeitlin S, Liu JP, Chapman DL, et al. Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet. 1995;11:155-163.
-
(1995)
Nat Genet
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
-
63
-
-
9344227302
-
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
-
Goldberg YP, Nicholson DW, Rasper DM, et al. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract. Nat Genet. 1996;13:442-449.
-
(1996)
Nat Genet
, vol.13
, pp. 442-449
-
-
Goldberg, Y.P.1
Nicholson, D.W.2
Rasper, D.M.3
-
64
-
-
0032502715
-
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
-
Wellington CL, Ellerby LM, Hackam AS, et al. Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract. J Biol Chem. 1998;273:9158-9167.
-
(1998)
J Biol Chem
, vol.273
, pp. 9158-9167
-
-
Wellington, C.L.1
Ellerby, L.M.2
Hackam, A.S.3
-
65
-
-
0031680014
-
A cellular model that recapitulates major pathogenic steps of Huntington's disease
-
Lunkes A, Mandel JL. A cellular model that recapitulates major pathogenic steps of Huntington's disease. Hum Mol Genet. 1998; 7:1355-1361.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1355-1361
-
-
Lunkes, A.1
Mandel, J.L.2
-
66
-
-
0032101287
-
The influence of huntingtin protein size on nuclear localization and cellular toxicity
-
Hackam AS, Singaraja R, Wellington CL, et al. The influence of huntingtin protein size on nuclear localization and cellular toxicity. J Cell Biol. 1998;141:1097-1105.
-
(1998)
J Cell Biol
, vol.141
, pp. 1097-1105
-
-
Hackam, A.S.1
Singaraja, R.2
Wellington, C.L.3
-
67
-
-
0030058208
-
Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo
-
Ikeda H, Yamaguchi M, Sugai S, et al. Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo. Nat Genet. 1996;13:196-202.
-
(1996)
Nat Genet
, vol.13
, pp. 196-202
-
-
Ikeda, H.1
Yamaguchi, M.2
Sugai, S.3
-
68
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick JM, Paulson HL, Gray-Board GL, et al. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell. 1998;93:939-949.
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.L.2
Gray-Board, G.L.3
-
69
-
-
0030806869
-
DNA damage distribution in the human brain as shown by in situ end labeling: Area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology
-
Masliah E, Mallory M, Alford M, et al. DNA damage distribution in the human brain as shown by in situ end labeling: area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology. J Neuropathol Exp Neurol. 1997;56:887-900.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 887-900
-
-
Masliah, E.1
Mallory, M.2
Alford, M.3
-
70
-
-
0030638139
-
Bax protein expression is increased in Alzheimer's brain: Correlations with DNA damage, Bcl-2 expression, and brain pathology
-
Su JH, Deng G, Cotman CW. Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. J Neuropathol Exp Neurol. 1997;56: 86-93.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 86-93
-
-
Su, J.H.1
Deng, G.2
Cotman, C.W.3
-
71
-
-
0028833215
-
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
-
Lassmann H, Bancher C, Breitschopf H, et al. Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol (Berl). 1995;89:35-41.
-
(1995)
Acta Neuropathol (Berl)
, vol.89
, pp. 35-41
-
-
Lassmann, H.1
Bancher, C.2
Breitschopf, H.3
-
72
-
-
0029120647
-
Evidence for apoptotic cell death in Alzheimer's disease
-
Smale G, Nichols NR, Brady DR, et al. Evidence for apoptotic cell death in Alzheimer's disease. Exp Neurol. 1995;133:225-230.
-
(1995)
Exp Neurol
, vol.133
, pp. 225-230
-
-
Smale, G.1
Nichols, N.R.2
Brady, D.R.3
-
73
-
-
0029976253
-
DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay
-
Anderson AJ, Su JH, Cotman CW. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. J Neurosci. 1996;16:1710-1719.
-
(1996)
J Neurosci
, vol.16
, pp. 1710-1719
-
-
Anderson, A.J.1
Su, J.H.2
Cotman, C.W.3
-
74
-
-
0029852587
-
In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: Correlations with senile plaques and disease progression
-
Troncoso JC, Sukhov RR, Kawas CH, Koliatsos VE. In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: correlations with senile plaques and disease progression. J Neuropathol Exp Neurol. 1996;55:1134-1142.
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1134-1142
-
-
Troncoso, J.C.1
Sukhov, R.R.2
Kawas, C.H.3
Koliatsos, V.E.4
-
75
-
-
0031958152
-
Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease
-
Cotman CW. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease. Neurobiol Aging. 1998;19:S29-S32.
-
(1998)
Neurobiol Aging
, vol.19
-
-
Cotman, C.W.1
-
76
-
-
2642680857
-
Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis
-
Stadelmann C, Bruck W, Bancher C, et al. Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis. J Neuropathol Exp Neurol. 1998;57:456-464.
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 456-464
-
-
Stadelmann, C.1
Bruck, W.2
Bancher, C.3
-
77
-
-
0030638139
-
Bax protein expression is increased in Alzheimer's brain: Correlations with DNA damage, Bcl-2 expression, and brain pathology
-
Anderson AJ, Su JH, Cotman CW. Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. J Neuropathol Exp Neurol. 1997;56:86-93.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 86-93
-
-
Anderson, A.J.1
Su, J.H.2
Cotman, C.W.3
-
78
-
-
0031471277
-
Apoptosis-related protein expression in the hippocampus in Alzheimer's disease
-
Marcus DL, Strafaci JA, Miller DC, et al. Apoptosis-related protein expression in the hippocampus in Alzheimer's disease. Neurobiol Aging. 1997;18:565-571.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 565-571
-
-
Marcus, D.L.1
Strafaci, J.A.2
Miller, D.C.3
-
79
-
-
0031044644
-
Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus
-
MacGibbon GA, Lawlor PA, Sirimanne ES, et al. Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus. Brain Res. 1997;750:223-234.
-
(1997)
Brain Res
, vol.750
, pp. 223-234
-
-
MacGibbon, G.A.1
Lawlor, P.A.2
Sirimanne, E.S.3
-
80
-
-
0032513029
-
Expression of ced-3 and ced-9 homologs in Alzheimer's disease cerebral cortex
-
Alcazar A, Regidor I, Masjuan J, et al. Expression of ced-3 and ced-9 homologs in Alzheimer's disease cerebral cortex. Neurosci Lett. 1998;244:69-72.
-
(1998)
Neurosci Lett
, vol.244
, pp. 69-72
-
-
Alcazar, A.1
Regidor, I.2
Masjuan, J.3
-
81
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
-
Yankner BA, Duffy LK, Kirschner DA. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science. 1990;250:279-282.
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
83
-
-
0029031348
-
Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent
-
Gschwind M, Huber G. Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J Neurochem. 1995; 65:292-300.
-
(1995)
J Neurochem
, vol.65
, pp. 292-300
-
-
Gschwind, M.1
Huber, G.2
-
84
-
-
0027257708
-
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons
-
Loo DT, Copani A, Pike CJ, et al. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA. 1993;90:7951-7955.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
-
85
-
-
0031982670
-
Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease
-
Mattson MP, Guo Q, Furukawa K, Pedersen WA. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. J Neurochem. 1998;70:1-14.
-
(1998)
J Neurochem
, vol.70
, pp. 1-14
-
-
Mattson, M.P.1
Guo, Q.2
Furukawa, K.3
Pedersen, W.A.4
-
86
-
-
0032487648
-
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites
-
Mattson MP, Partin J, Begley JG. Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites. Brain Res. 1998;807:167-176.
-
(1998)
Brain Res
, vol.807
, pp. 167-176
-
-
Mattson, M.P.1
Partin, J.2
Begley, J.G.3
-
87
-
-
0030986669
-
Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
-
Kruman I, Bruce-Keller AJ, Bredesen D, et al. Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J Neurosci. 1997;17:5089-5100.
-
(1997)
J Neurosci
, vol.17
, pp. 5089-5100
-
-
Kruman, I.1
Bruce-Keller, A.J.2
Bredesen, D.3
-
88
-
-
0028207907
-
Amyloid beta peptide induces necrosis rather than apoptosis
-
Behl C, Davis JB, Klier FG, Schubert D. Amyloid beta peptide induces necrosis rather than apoptosis. Brain Res. 1994;645:253-264.
-
(1994)
Brain Res
, vol.645
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
Klier, F.G.3
Schubert, D.4
-
89
-
-
0032053984
-
Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer
-
Nishimura I, Uetsuki T, Dani SU, et al. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer. J Neurosci. 1998;18:2387-2398.
-
(1998)
J Neurosci
, vol.18
, pp. 2387-2398
-
-
Nishimura, I.1
Uetsuki, T.2
Dani, S.U.3
-
90
-
-
15844386159
-
G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP
-
Yamatsuji T, Matsui T, Okamoto T, et al. G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP. Science. 1996;272:1349-1352.
-
(1996)
Science
, vol.272
, pp. 1349-1352
-
-
Yamatsuji, T.1
Matsui, T.2
Okamoto, T.3
-
91
-
-
0030042249
-
Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype
-
Yamatsuji T, Okamoto T, Takeda S, et al. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype. Embo J. 1996;15:498-509.
-
(1996)
Embo J
, vol.15
, pp. 498-509
-
-
Yamatsuji, T.1
Okamoto, T.2
Takeda, S.3
-
92
-
-
0032400818
-
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis
-
Bursztajn S, DeSouza R, McPhie DL, et al. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. J Neurosci. 1998;18: 9790-9799.
-
(1998)
J Neurosci
, vol.18
, pp. 9790-9799
-
-
Bursztajn, S.1
Desouza, R.2
McPhie, D.L.3
-
93
-
-
0030738912
-
G protein beta-gamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP
-
Giambarella U, Yamatsuji T, Okamoto T, et al. G protein beta-gamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. Embo J. 1997;16:4897-4907.
-
(1997)
Embo J
, vol.16
, pp. 4897-4907
-
-
Giambarella, U.1
Yamatsuji, T.2
Okamoto, T.3
-
94
-
-
0031034226
-
Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells
-
Zhao B, Chrest FJ, Horton WE Jr, et al. Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells. J Neurosci Res. 1997;47:253-263.
-
(1997)
J Neurosci Res
, vol.47
, pp. 253-263
-
-
Zhao, B.1
Chrest, F.J.2
Horton W.E., Jr.3
-
96
-
-
0027996904
-
Expression of the low-affinity nerve growth factor receptor enhances beta-amyloid peptide toxicity
-
Rabizadeh S, Bitler CM, Butcher LL, Bredesen DE. Expression of the low-affinity nerve growth factor receptor enhances beta-amyloid peptide toxicity. Proc Natl Acad Sci USA. 1994;91:10703-10706.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10703-10706
-
-
Rabizadeh, S.1
Bitler, C.M.2
Butcher, L.L.3
Bredesen, D.E.4
-
97
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell. 1994;77:817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
99
-
-
0029056516
-
Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: The role of nitric oxide and NMDA-gated channel activation leading to apoptosis
-
Le WD, Colom LV, Xie WJ, et al. Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis. Brain Res. 1995;686:49-60.
-
(1995)
Brain Res
, vol.686
, pp. 49-60
-
-
Le, W.D.1
Colom, L.V.2
Xie, W.J.3
-
100
-
-
0029813177
-
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
-
Masliah E, Sisk A, Mallory M, et al. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J Neurosci. 1996;16:5795-5811.
-
(1996)
J Neurosci
, vol.16
, pp. 5795-5811
-
-
Masliah, E.1
Sisk, A.2
Mallory, M.3
-
101
-
-
0030611750
-
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
-
Mattson MP, Goodman Y, Luo H, et al. Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. J Neurosci Res. 1997;49:681-697.
-
(1997)
J Neurosci Res
, vol.49
, pp. 681-697
-
-
Mattson, M.P.1
Goodman, Y.2
Luo, H.3
-
102
-
-
0032539814
-
Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: Reduced oxidative stress and preserved mitochondrial function
-
Guo Q, Christakos S, Robinson N, Mattson MP. Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function. Proc Natl Acad Sci USA. 1998;95:3227-3232.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3227-3232
-
-
Guo, Q.1
Christakos, S.2
Robinson, N.3
Mattson, M.P.4
-
103
-
-
0030891662
-
Alzheimer's PS-1 mutation perturbs calcium homeostasis, and sensitizes PC12 cells to death induced by amyloid beta-peptide
-
Guo Q, Furukawa K, Sopher BL, et al. Alzheimer's PS-1 mutation perturbs calcium homeostasis, and sensitizes PC12 cells to death induced by amyloid beta-peptide. Neuroreport. 1996;8:379-383.
-
(1996)
Neuroreport
, vol.8
, pp. 379-383
-
-
Guo, Q.1
Furukawa, K.2
Sopher, B.L.3
-
104
-
-
0030917601
-
Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal, and amyloid beta-peptide. involvement of calcium and oxyradicals
-
Guo Q, Sopher BL, Furukawa K, et al. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal, and amyloid beta-peptide. involvement of calcium and oxyradicals. J Neurosci. 1997;17:4212-4222.
-
(1997)
J Neurosci
, vol.17
, pp. 4212-4222
-
-
Guo, Q.1
Sopher, B.L.2
Furukawa, K.3
-
105
-
-
0031927628
-
Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease
-
Guo Q, Fu W, Xie J, et al. Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease. Nat Med. 1998;4:957-962.
-
(1998)
Nat Med
, vol.4
, pp. 957-962
-
-
Guo, Q.1
Fu, W.2
Xie, J.3
-
106
-
-
0030868903
-
Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease
-
Kim TW, Pettingell WH, Jung YK, et al. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science. 1997;277:373-376.
-
(1997)
Science
, vol.277
, pp. 373-376
-
-
Kim, T.W.1
Pettingell, W.H.2
Jung, Y.K.3
-
107
-
-
0031593685
-
Inhibition of presenilin 1 expression is promoted by p53 andp21WAF-1 and results in apoptosis and tumor suppression
-
Roperch JP, Alvaro V, Prieur S, et al. Inhibition of presenilin 1 expression is promoted by p53 andp21WAF-1 and results in apoptosis and tumor suppression. Nat Med. 1998;4:835-838.
-
(1998)
Nat Med
, vol.4
, pp. 835-838
-
-
Roperch, J.P.1
Alvaro, V.2
Prieur, S.3
-
108
-
-
0029856850
-
Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3
-
Vito P, Wolozin B, Ganjei JK, et al. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. J Biol Chem. 1996;271:31025-31028.
-
(1996)
J Biol Chem
, vol.271
, pp. 31025-31028
-
-
Vito, P.1
Wolozin, B.2
Ganjei, J.K.3
-
109
-
-
0030771534
-
Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I)
-
Janicki S, Monteiro MJ. Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I). J Cell Biol. 1997;139:485-495.
-
(1997)
J Cell Biol
, vol.139
, pp. 485-495
-
-
Janicki, S.1
Monteiro, M.J.2
-
110
-
-
0030580281
-
Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells
-
Deng G, Pike CJ, Cotman CW. Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells. FEBS Lett. 1996;397:50-54.
-
(1996)
FEBS Lett
, vol.397
, pp. 50-54
-
-
Deng, G.1
Pike, C.J.2
Cotman, C.W.3
-
111
-
-
10544224542
-
Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
-
Wolozin B, Iwasaki K, Vito P, et al. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science. 1996;274:1710-1713.
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
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