-
1
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
-
Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (Lond.), 284: 555-556, 1980.
-
(1980)
Nature (Lond.)
, vol.284
, pp. 555-556
-
-
Wyllie, A.H.1
-
2
-
-
0028939862
-
The genetic regulation of apoptosis
-
Wyllie, A. H. The genetic regulation of apoptosis. Curr. Opin. Genet. Dev., 5: 97-104, 1995.
-
(1995)
Curr. Opin. Genet. Dev.
, vol.5
, pp. 97-104
-
-
Wyllie, A.H.1
-
3
-
-
0025247903
-
Apoptosis: The role of the endonuclease
-
Arends, M. J., Morris, R. G, and Wyllie, A. H. Apoptosis: the role of the endonuclease. Am. J. Pathol., 136: 593-608, 1990.
-
(1990)
Am. J. Pathol.
, vol.136
, pp. 593-608
-
-
Arends, M.J.1
Morris, R.G.2
Wyllie, A.H.3
-
4
-
-
0019225636
-
Cell death: The significance of apoptosis
-
Wyllie, A. H., Kerr, J. F. R., and Currie, A. R. Cell death: the significance of apoptosis. Int. Rev. Cytol., 68: 251-306, 1980.
-
(1980)
Int. Rev. Cytol.
, vol.68
, pp. 251-306
-
-
Wyllie, A.H.1
Kerr, J.F.R.2
Currie, A.R.3
-
5
-
-
0027458695
-
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis. (programmed cell death)
-
Peitsch, M. C., Polzar, B., Stephan, H., Crompton, T., MacDonald H. R., Mannherz H. G., and Tschopp, J. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis. (programmed cell death). EMBO J., 12: 371-377, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 371-377
-
-
Peitsch, M.C.1
Polzar, B.2
Stephan, H.3
Crompton, T.4
MacDonald, H.R.5
Mannherz, H.G.6
Tschopp, J.7
-
6
-
-
0026006943
-
Identification, purification, and characterization of a calcium dependent endonuclease (NUC 18) from apoptotic rat thymocytes. NUC18 is not histone H2B
-
Gaido, M. L., and Cidlowski, J. A. Identification, purification, and characterization of a calcium dependent endonuclease (NUC 18) from apoptotic rat thymocytes. NUC18 is not histone H2B. J. Biol. Chem., 266: 18580-18585, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18580-18585
-
-
Gaido, M.L.1
Cidlowski, J.A.2
-
7
-
-
0027164993
-
Identification of deoxyribonuclease II as an endonuclease involved in apoptosis
-
Barry, A., and Eastman, A. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis. Arch. Biochem. Biophys., 300: 440-450, 1993.
-
(1993)
Arch. Biochem. Biophys.
, vol.300
, pp. 440-450
-
-
Barry, A.1
Eastman, A.2
-
8
-
-
0027791369
-
2+-dependent endonuclease from human spleen: Purification, properties, and role in apoptosis
-
2+-dependent endonuclease from human spleen: purification, properties, and role in apoptosis. Biochemistry, 32: 9129-9136, 1993.
-
(1993)
Biochemistry
, vol.32
, pp. 9129-9136
-
-
Ribeiro, J.M.1
Carson, D.A.2
-
9
-
-
0030043120
-
2+-dependent endonuclease associated with apoptosis
-
2+-dependent endonuclease associated with apoptosis. J. Immunol., 156: 922-931, 1996.
-
(1996)
J. Immunol.
, vol.156
, pp. 922-931
-
-
Khodarev, N.K.1
Ashwell, J.D.2
-
10
-
-
0031046748
-
Identification of a novel 97 kDa endonuclease capable of internucleosomal DNa cleavage
-
Pandey, S., Walker, P. R., and Sikorska, M. Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage. Biochemistry, 36: 711-720, 1997.
-
(1997)
Biochemistry
, vol.36
, pp. 711-720
-
-
Pandey, S.1
Walker, P.R.2
Sikorska, M.3
-
11
-
-
0030830050
-
Purification and properties of DNase γ from apoptotic rat thymocytes
-
Shiokawa, D., Ohyama, H., Yamada, T., and Tanuma, S. Purification and properties of DNase γ from apoptotic rat thymocytes. Biochem. J., 326: 675-681, 1997.
-
(1997)
Biochem. J.
, vol.326
, pp. 675-681
-
-
Shiokawa, D.1
Ohyama, H.2
Yamada, T.3
Tanuma, S.4
-
12
-
-
0024507195
-
2+ concentration
-
2+ concentration. Arch. Biochem. Biophys., 269: 365-370, 1989.
-
(1989)
Arch. Biochem. Biophys.
, vol.269
, pp. 365-370
-
-
McConkey, D.J.1
Nicotera, P.2
Hartzell, P.3
Bellomo, G.4
Wyllie, A.H.5
Orrenius, S.6
-
15
-
-
0027278822
-
Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification
-
Barry, M. A., Reynolds, J. E., and Eastman, A. Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification. Cancer Res., 53: 2349-2357, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2349-2357
-
-
Barry, M.A.1
Reynolds, J.E.2
Eastman, A.3
-
16
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature (Lond.), 371: 346-347, 1994.
-
(1994)
Nature (Lond.)
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
17
-
-
0029068871
-
Identification and inhibition of ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T. T., Yu, V. L., and Miller, D. K. Identification and inhibition of ICE/CED-3 protease necessary for mammalian apoptosis. Nature (Lond.), 376: 37-43, 1995.
-
(1995)
Nature (Lond.)
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
18
-
-
0028885544
-
Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis
-
Martin, S. J., Newmeyer, D. D., Mathias, S., Farschon, D. M., Wang, H. G., Reed, J. C., Kolesnick, R. N., and Green, D. R. Cell-free reconstitution of Fas-, UV radiation-and ceramide-induced apoptosis. EMBO J., 14: 5191-5200, 1995.
-
(1995)
EMBO J.
, vol.14
, pp. 5191-5200
-
-
Martin, S.J.1
Newmeyer, D.D.2
Mathias, S.3
Farschon, D.M.4
Wang, H.G.5
Reed, J.C.6
Kolesnick, R.N.7
Green, D.R.8
-
19
-
-
0029853389
-
Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways
-
Dubrez, L., Savoy, I., Hamman, A., and Solary, E. Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways. EMBO J., 15: 5504-5512, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 5504-5512
-
-
Dubrez, L.1
Savoy, I.2
Hamman, A.3
Solary, E.4
-
20
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature (Lond.), 391: 43-50, 1998.
-
(1998)
Nature (Lond.)
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
21
-
-
0029927422
-
The role of proteases during apoptosis
-
Patel, T., Gores, G. J., and Kaufman, S, H. The role of proteases during apoptosis. FASEB J., 10: 587-597, 1996.
-
(1996)
FASEB J.
, vol.10
, pp. 587-597
-
-
Patel, T.1
Gores, G.J.2
Kaufman, S.H.3
-
22
-
-
0029125701
-
Protease activation during apoptosis: Death by a thousand cuts?
-
Martin, S. J., and Green, D, R. Protease activation during apoptosis: death by a thousand cuts? Cell: 82:349-352, 1995.
-
(1995)
Cell
, vol.82
, pp. 349-352
-
-
Martin, S.J.1
Green, D.R.2
-
23
-
-
0024470862
-
Induction of endonucleolytic DNa cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
-
Kaufmann, S. H. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res., 49: 5870-5878, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5870-5878
-
-
Kaufmann, S.H.1
-
24
-
-
0026332184
-
Differential induction of secondary fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression
-
Bertrand, R., Sarang, M., Jenkins, J. Kerrigan, D., and Pommier, Y. Differential induction of secondary fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression. Cancer Res., 51: 6280-6285, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6280-6285
-
-
Bertrand, R.1
Sarang, M.2
Jenkins, J.3
Kerrigan, D.4
Pommier, Y.5
-
25
-
-
0027403207
-
Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors
-
Solary, E., Bertrand, R., Kohn, K. W., and Pommier, Y. Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors. Blood, 81: 1359-1368, 1993.
-
(1993)
Blood
, vol.81
, pp. 1359-1368
-
-
Solary, E.1
Bertrand, R.2
Kohn, K.W.3
Pommier, Y.4
-
26
-
-
0025185463
-
Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis
-
Martin, S. J., Lennon, S. V., Bonham, A. M., and Cotter, T. G. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J. Immunol., 145: 1859-1867, 1990.
-
(1990)
J. Immunol.
, vol.145
, pp. 1859-1867
-
-
Martin, S.J.1
Lennon, S.V.2
Bonham, A.M.3
Cotter, T.G.4
-
27
-
-
0031213555
-
7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53
-
Shao, R. G., Shimizu, T., and Pommier, Y. 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. Exp. Cell Res., 234: 388-397, 1997.
-
(1997)
Exp. Cell Res.
, vol.234
, pp. 388-397
-
-
Shao, R.G.1
Shimizu, T.2
Pommier, Y.3
-
28
-
-
0030926327
-
Androgen ablation leads to an upregulation and intranuclear accumulation of deoxyribonuclease I in rat prostate epithelial cells paralleling their apoptotic elimination
-
Rauch, F., Polzar, B., Stephan, H., Zanotti, S., Paddenberg, R., and Mannherz, H. G. Androgen ablation leads to an upregulation and intranuclear accumulation of deoxyribonuclease I in rat prostate epithelial cells paralleling their apoptotic elimination J. Cell Biol., 137: 909-923, 1997.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 909-923
-
-
Rauch, F.1
Polzar, B.2
Stephan, H.3
Zanotti, S.4
Paddenberg, R.5
Mannherz, H.G.6
-
29
-
-
0022253232
-
Purification of DNA from formaldehyde fixed and paraffin embedded human tissue
-
Goelz, S. E., Hamilton, S. R., and Vogelstein, B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem. Biophys. Res. Commun., 130: 118-126, 1985.
-
(1985)
Biochem. Biophys. Res. Commun.
, vol.130
, pp. 118-126
-
-
Goelz, S.E.1
Hamilton, S.R.2
Vogelstein, B.3
-
30
-
-
0026498970
-
Inhibitors of proteases prevent endonucleolysis accompanying apoptotic death of HL-60 leukemic cells and normal thymocytes
-
Baltimore
-
Bruno, S., Dell Bino, G., Lassota, P., Giaretti, W., and Darzynkiewicz, Z. Inhibitors of proteases prevent endonucleolysis accompanying apoptotic death of HL-60 leukemic cells and normal thymocytes. Leukemia (Baltimore), 6: 1113-1120, 1992.
-
(1992)
Leukemia
, vol.6
, pp. 1113-1120
-
-
Bruno, S.1
Dell Bino, G.2
Lassota, P.3
Giaretti, W.4
Darzynkiewicz, Z.5
-
31
-
-
0027255417
-
Specific proteolytic cleavage of poly (ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res., 53: 3976-3985, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
32
-
-
0027971322
-
Purification of a 24-kD protease from apoptotic tumor cells that activates DNa fragmentation
-
Wright, S. C., Wei, Q. S., Zhong, J., Zheng, H., Kinder, D. H., and Larrick, J. W. Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation. J. Exp. Med., 180: 2113-2123, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2113-2123
-
-
Wright, S.C.1
Wei, Q.S.2
Zhong, J.3
Zheng, H.4
Kinder, D.H.5
Larrick, J.W.6
-
33
-
-
0028924496
-
Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes
-
Chow, S. C., Weis, M., Kass, G. E., Holmstrom, T. H., Eriksson, J. E., and Orrenius, S. Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes. FEBS Lett., 364: 134-138, 1995.
-
(1995)
FEBS Lett.
, vol.364
, pp. 134-138
-
-
Chow, S.C.1
Weis, M.2
Kass, G.E.3
Holmstrom, T.H.4
Eriksson, J.E.5
Orrenius, S.6
-
34
-
-
1842376234
-
Serine protease inhibitors block neutralsphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
-
Mansat, V., Bettaieb, A., Levade, T., Laurent, G., and Jaffrezou, J. P. Serine protease inhibitors block neutralsphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. FASEB J., 11: 695-702, 1997.
-
(1997)
FASEB J.
, vol.11
, pp. 695-702
-
-
Mansat, V.1
Bettaieb, A.2
Levade, T.3
Laurent, G.4
Jaffrezou, J.P.5
-
35
-
-
0030890790
-
Processing/ activation of at least four interleukin-1β converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells
-
MacFarlane, M., Cain, K., Sun, X, M., Alnemri, E. S., and Cohen, G. M. Processing/ activation of at least four interleukin-1β converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells. J. Cell Biol., 137: 469-479, 1997.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 469-479
-
-
MacFarlane, M.1
Cain, K.2
Sun, X.M.3
Alnemri, E.S.4
Cohen, G.M.5
-
36
-
-
0016361516
-
Actin is the naturally occurring inhibitor of deoxyribonuclease I
-
Lazarides, E., and Lindberg, U. Actin is the naturally occurring inhibitor of deoxyribonuclease I. Proc. Natl. Acad. Sci. USA, 71: 4742-4746, 1974.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 4742-4746
-
-
Lazarides, E.1
Lindberg, U.2
-
37
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli, Y., Sherman, Y., and Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119: 493-501, 1992.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
38
-
-
0027267981
-
DNA fragmentation during apoptosis is caused by frequent single-strand cuts
-
Peitsch, M. C., Muller, C., and Tschopp, J. DNA fragmentation during apoptosis is caused by frequent single-strand cuts. Nucleic Acids Res., 21: 4206-4209, 1993.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4206-4209
-
-
Peitsch, M.C.1
Muller, C.2
Tschopp, J.3
-
39
-
-
0001088630
-
Evidence that DNA fragmentation in apoptosis is initiated and propagated by single-strand breaks
-
Walker, P. R., Leblanc, J., and Sikorska, M. Evidence that DNA fragmentation in apoptosis is initiated and propagated by single-strand breaks. Cell Death Differ., 4: 506-515, 1997.
-
(1997)
Cell Death Differ.
, vol.4
, pp. 506-515
-
-
Walker, P.R.1
Leblanc, J.2
Sikorska, M.3
-
42
-
-
0019887828
-
Deoxyribonuclease I in mammalian tissues. Specificity of inhibition by actin
-
Lacks, S. A. Deoxyribonuclease I in mammalian tissues. Specificity of inhibition by actin. J. Biol. Chem., 256: 2644-2648, 1981.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 2644-2648
-
-
Lacks, S.A.1
-
43
-
-
0019887769
-
Purification and properties of an endodeoxyribonuclease from nuclei of bovine small intestinal mucosa
-
Nakayama, J., Fujiyoshi, T., Nakamura, M., and Anai, M. Purification and properties of an endodeoxyribonuclease from nuclei of bovine small intestinal mucosa. J. Biol. Chem., 256: 1636-1642, 1981.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 1636-1642
-
-
Nakayama, J.1
Fujiyoshi, T.2
Nakamura, M.3
Anai, M.4
-
44
-
-
0017900326
-
An endodeoxyribonuclease of human KB cells. Purification and properties of the enzyme
-
Tsuruo, T., Arens, M., Padmanabhan, R., and Green, M. An endodeoxyribonuclease of human KB cells. Purification and properties of the enzyme. J. Biol. Chem., 253: 3400-3407, 1978.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 3400-3407
-
-
Tsuruo, T.1
Arens, M.2
Padmanabhan, R.3
Green, M.4
-
45
-
-
0023719582
-
Purification and properties of a magnesium-dependent endodeoxyribonuclease endogenous to rat-liver nuclei
-
Hibino, Y., Yoneda, T., and Sugano, N. Purification and properties of a magnesium-dependent endodeoxyribonuclease endogenous to rat-liver nuclei. Biochim. Biophys. Acta, 950: 313-320, 1988.
-
(1988)
Biochim. Biophys. Acta
, vol.950
, pp. 313-320
-
-
Hibino, Y.1
Yoneda, T.2
Sugano, N.3
-
46
-
-
0014382423
-
Mechanism of action and structure of acid deoxyribonuclease
-
Bernardi, G. Mechanism of action and structure of acid deoxyribonuclease. Adv. Enzymol., 31: 1-7, 1968.
-
(1968)
Adv. Enzymol.
, vol.31
, pp. 1-7
-
-
Bernardi, G.1
-
47
-
-
0030810259
-
Intracellular acidification is associated with, but not required for caspase activation, DNA fragmentation or apoptosis
-
Reynolds, J. E., Wolf, C. M., and Eastman, A. Intracellular acidification is associated with, but not required for caspase activation, DNA fragmentation or apoptosis. Int. J. Oncol., 11: 1241-1246, 1997.
-
(1997)
Int. J. Oncol.
, vol.11
, pp. 1241-1246
-
-
Reynolds, J.E.1
Wolf, C.M.2
Eastman, A.3
-
48
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira, H., Enari, M., and Nagata, S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature (Lond.), 391: 96-99, 1998.
-
(1998)
Nature (Lond.)
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
|