-
1
-
-
0030297919
-
Adipogenesis and obesity: Rounding out the big picture
-
Spiegelman BM, Flier JS. Adipogenesis and obesity: rounding out the big picture. Cell 1996; 87: 377-89.
-
(1996)
Cell
, vol.87
, pp. 377-389
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
2
-
-
0030794057
-
Peroxisome proliferator-activated receptors, orphans with ligands and functions
-
Schoonjans K, Marin G, Staels B, Auwerx J. Peroxisome proliferator-activated receptors, orphans with ligands and functions. Curr Opin Lipidol 1997; 8: 159-65.
-
(1997)
Curr Opin Lipidol
, vol.8
, pp. 159-165
-
-
Schoonjans, K.1
Marin, G.2
Staels, B.3
Auwerx, J.4
-
3
-
-
0000101746
-
PPAR: A key nuclear factor in nutrient / gene interactions
-
Bauerle P, ed. Boston: Birkhauser
-
Desvergne B, Wahli W. PPAR: a key nuclear factor in nutrient / gene interactions. In: Bauerle P, ed. Inducible Gene Expression. Vol 1. Boston: Birkhauser; 1994: 142-76.
-
(1994)
Inducible Gene Expression
, vol.1
, pp. 142-176
-
-
Desvergne, B.1
Wahli, W.2
-
4
-
-
0029102676
-
Structural organization of mouse peroxisome proliferator activated receptor γ (mPPARγ) gene: Alternative promoter use and different splicing yield two mPPARγ isoforms
-
Zhu Y, Qi C, Korenberg JR, Chen XN, Noya D, Rao MS, et al. Structural organization of mouse peroxisome proliferator activated receptor γ (mPPARγ) gene: alternative promoter use and different splicing yield two mPPARγ isoforms. Proc Natl Acad Sci U S A 1995; 92: 7921-5.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7921-7925
-
-
Zhu, Y.1
Qi, C.2
Korenberg, J.R.3
Chen, X.N.4
Noya, D.5
Rao, M.S.6
-
5
-
-
0030835678
-
Organization, promoter analysis and expression of the human PPARγ gene
-
Fajas L, Auboeuf D, Raspe E, Schoonjans K, Lefebvre AM, Saladin R, et al. Organization, promoter analysis and expression of the human PPARγ gene. J Biol Chem 1997; 272: 18779-89.
-
(1997)
J Biol Chem
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
-
6
-
-
0032582349
-
PPARγ3 mRNA: A distinct PPARγ mRNA subtype transcribed from an independent promoter
-
Fajas L, Fruchart JC, Auwerx J. PPARγ3 mRNA: a distinct PPARγ mRNA subtype transcribed from an independent promoter. FEBS Lett 1998; 438: 55-60.
-
(1998)
FEBS Lett
, vol.438
, pp. 55-60
-
-
Fajas, L.1
Fruchart, J.C.2
Auwerx, J.3
-
7
-
-
0029994543
-
Role of the peroxisome proliferator activated receptor (PPAR) in mediating effects of fibrates and fatty acids on gene expression
-
Schoonjans K, Staels B, Auwerx J. Role of the peroxisome proliferator activated receptor (PPAR) in mediating effects of fibrates and fatty acids on gene expression. J Lipid Res 1996; 37: 907-25.
-
(1996)
J Lipid Res
, vol.37
, pp. 907-925
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
8
-
-
0342959286
-
Tissue distribution and quantification of the expression of PPARs and LXRα in humans: No alterations in adipose tissue of obese and NIDDM patients
-
Auboeuf D, Rieusset J, Fajas L, Vallier P, Frering V, Riou JP, et al. Tissue distribution and quantification of the expression of PPARs and LXRα in humans: no alterations in adipose tissue of obese and NIDDM patients. Diabetes 1997; 48: 1319-27.
-
(1997)
Diabetes
, vol.48
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
-
9
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, et al. Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A 1998; 95: 7614-9.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7614-7619
-
-
Ricote, M.1
Huang, J.2
Fajas, L.3
Li, A.4
Welch, J.5
Najib, J.6
-
10
-
-
0031964987
-
Depot-specific differences in adipose tissue gene expression in lean and obese subjects
-
Lefebvre AM, Laville M, Vega N, Riou JP, van Gaal L, Auwerx J, et al. Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes 1998; 47: 98-103.
-
(1998)
Diabetes
, vol.47
, pp. 98-103
-
-
Lefebvre, A.M.1
Laville, M.2
Vega, N.3
Riou, J.P.4
Van Gaal, L.5
Auwerx, J.6
-
11
-
-
0032994523
-
Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor γ in human adipocytes
-
Rieusset J, Andreelli D, Auboeuf D, Roques M, Vallier P, Riou JP, et al. Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor γ in human adipocytes. Diabetes 1999; 48: 699-705.
-
(1999)
Diabetes
, vol.48
, pp. 699-705
-
-
Rieusset, J.1
Andreelli, D.2
Auboeuf, D.3
Roques, M.4
Vallier, P.5
Riou, J.P.6
-
12
-
-
0030977450
-
Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Pulg AJ, Considine RV, Jimenez-Linan M, Werman A, Pories WJ, Caro JF, et al. Peroxisome proliferator-activated receptor gene expression in human tissues: effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 1997; 99: 2416-22.
-
(1997)
J Clin Invest
, vol.99
, pp. 2416-2422
-
-
Vidal-Pulg, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
Werman, A.4
Pories, W.J.5
Caro, J.F.6
-
13
-
-
0030972203
-
TNFα-mediated inhibition and reversal of adipocyte differentiation is accompanied by suppressed expression of PPARγ without effects on Pref-1 expression
-
Xing H, Northrop JP, Grove JR, Kilpatrick KE, Su JL, Ringold GM. TNFα-mediated inhibition and reversal of adipocyte differentiation is accompanied by suppressed expression of PPARγ without effects on Pref-1 expression. Endocrinology 1997; 138: 2776-83.
-
(1997)
Endocrinology
, vol.138
, pp. 2776-2783
-
-
Xing, H.1
Northrop, J.P.2
Grove, J.R.3
Kilpatrick, K.E.4
Su, J.L.5
Ringold, G.M.6
-
14
-
-
0030957958
-
Decreased expression of murine PPARγ in adipose tissue during endotoxinemia
-
Hill M, Young M, McCurdy C, Gimble J. Decreased expression of murine PPARγ in adipose tissue during endotoxinemia. Endocrinology 1997; 138: 3073-6.
-
(1997)
Endocrinology
, vol.138
, pp. 3073-3076
-
-
Hill, M.1
Young, M.2
McCurdy, C.3
Gimble, J.4
-
16
-
-
0028878375
-
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
-
Yeh WC, Cao Z, Classon M, McKnight S. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev 1995; 9: 168-81.
-
(1995)
Genes Dev
, vol.9
, pp. 168-181
-
-
Yeh, W.C.1
Cao, Z.2
Classon, M.3
McKnight, S.4
-
17
-
-
0028971225
-
Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis
-
Wu Z, Xie Y, Bucher NLR, Farmer SR. Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis. Genes Dev 1995; 9: 2350-63.
-
(1995)
Genes Dev
, vol.9
, pp. 2350-2363
-
-
Wu, Z.1
Xie, Y.2
Bucher, N.L.R.3
Farmer, S.R.4
-
18
-
-
0029905399
-
Induction of peroxisome proliferator-activated receptor γ during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPβ, C/EBPδ, and glucocorticoids
-
Wu Z, Bucher NLR, Farmer SR. Induction of peroxisome proliferator-activated receptor γ during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPβ, C/EBPδ, and glucocorticoids. Mol Cell Biol 1996; 16: 4128-36.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4128-4136
-
-
Wu, Z.1
Bucher, N.L.R.2
Farmer, S.R.3
-
19
-
-
0033083803
-
Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity
-
Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, et al. Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 1999; 3: 143-50.
-
(1999)
Mol Cell
, vol.3
, pp. 143-150
-
-
Wu, Z.1
Rosen, E.D.2
Brun, R.3
Hauser, S.4
Adelmant, G.5
Troy, A.E.6
-
20
-
-
0032979514
-
Differential regulation of peroxisome proliferator activated receptor γ1 (PPARγ1) and PPARγ2 mRNA expression in early stages of adipogenesis
-
Saladin R, Fajas L, Dana S, Halvorsen YD, Auwerx J, Briggs M. Differential regulation of peroxisome proliferator activated receptor γ1 (PPARγ1) and PPARγ2 mRNA expression in early stages of adipogenesis. Cell Growth Differ 1999; 10: 43-8.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 43-48
-
-
Saladin, R.1
Fajas, L.2
Dana, S.3
Halvorsen, Y.D.4
Auwerx, J.5
Briggs, M.6
-
21
-
-
1842295133
-
Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corexpressors
-
DiRenzo J, Soderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingray S, et al. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corexpressors. Mol Cell Biol 1997; 17: 2166-76.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2166-2176
-
-
DiRenzo, J.1
Soderstrom, M.2
Kurokawa, R.3
Ogliastro, M.H.4
Ricote, M.5
Ingray, S.6
-
22
-
-
0029919647
-
Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ
-
Xue JC, Schwarz EJ, Chawla A, Lazar MA. Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ. Mol Cell Biol 1996; 16: 1567-75.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1567-1575
-
-
Xue, J.C.1
Schwarz, E.J.2
Chawla, A.3
Lazar, M.A.4
-
23
-
-
0027648820
-
ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
-
Tontonoz P, Kim JB, Graves RA, Spiegelman BM. ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol Cell Biol 1993; 13: 4753-9.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4753-4759
-
-
Tontonoz, P.1
Kim, J.B.2
Graves, R.A.3
Spiegelman, B.M.4
-
24
-
-
0030007427
-
ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
-
Kim JB, Spiegelman BM. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 1996; 10: 1096-107.
-
(1996)
Genes Dev
, vol.10
, pp. 1096-1107
-
-
Kim, J.B.1
Spiegelman, B.M.2
-
25
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 1996; 98: 1575-84.
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
-
26
-
-
0030020577
-
Sterol regulation of acetyl coenzyme A carboxylase: A mechanism for coordinate control of cellular lipid
-
Lopez JM, Bennett MK, Sanchez HB, Rosenfeld JM, Osborne TF. Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid. Proc Natl Acad Sci U S A 1996; 93: 1049-53.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1049-1053
-
-
Lopez, J.M.1
Bennett, M.K.2
Sanchez, H.B.3
Rosenfeld, J.M.4
Osborne, T.F.5
-
27
-
-
0028875426
-
Sterol regulation of fatty acid synthase promoter: Coordinate feedback regulation of two major lipid pathways
-
Bennet MK, Lopez JM, Sanchez HB, Osborne TF. Sterol regulation of fatty acid synthase promoter: coordinate feedback regulation of two major lipid pathways. J Biol Chem 1995; 270: 25578-83.
-
(1995)
J Biol Chem
, vol.270
, pp. 25578-25583
-
-
Bennet, M.K.1
Lopez, J.M.2
Sanchez, H.B.3
Osborne, T.F.4
-
29
-
-
0032793068
-
Regulation of PPARγ expression by ADD1/SREBP- 1: Implications for adipocyte differentiation and metabolism
-
Fajas L, Schoonjans K, Gelman L, Kim JB, Najib J, Martin G, et al. Regulation of PPARγ expression by ADD1/SREBP-1: implications for adipocyte differentiation and metabolism. Mol Cell Biol 1999; 19: 5495-503.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5495-5503
-
-
Fajas, L.1
Schoonjans, K.2
Gelman, L.3
Kim, J.B.4
Najib, J.5
Martin, G.6
-
30
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 1994; 79: 1147-56.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
31
-
-
0028871780
-
Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα
-
Hu E, Tontonoz P, Spiegelman BM. Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα. Proc Natl Acad Sci U S A 1995; 92: 9856-60.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9856-9860
-
-
Hu, E.1
Tontonoz, P.2
Spiegelman, B.M.3
-
32
-
-
0028180070
-
mPPARy2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM. mPPARy2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 1994; 8: 1224-34.
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
33
-
-
0028988487
-
PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz P, Hu E, Devine J, Beale EG, Spiegelman BM. PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol 1995; 15: 351-7.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
34
-
-
0027292101
-
Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation
-
Schoonjans K, Staels B, Grimaldi P, Auwerx J. Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation. Eur J Biochem 1993; 216: 615-22.
-
(1993)
Eur J Biochem
, vol.216
, pp. 615-622
-
-
Schoonjans, K.1
Staels, B.2
Grimaldi, P.3
Auwerx, J.4
-
35
-
-
0029144018
-
Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter
-
Schoonjans K, Watanabe M, Suzaki H, Mahfoudi A, Krey G, Wahli W, et al. Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem 1995; 270: 19269-76.
-
(1995)
J Biol Chem
, vol.270
, pp. 19269-19276
-
-
Schoonjans, K.1
Watanabe, M.2
Suzaki, H.3
Mahfoudi, A.4
Krey, G.5
Wahli, W.6
-
36
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93: 241-52.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
Thomazy, V.A.4
Evans, R.M.5
-
37
-
-
0030658022
-
Coordinate regulation of the expression of the fatty acid transport protein (FATP) and acyl CoA synthetase genes by PPARα and PPARγ activators
-
Martin G, Schoonjans K, Lefebvre A, Staels B, Auwerx J. Coordinate regulation of the expression of the fatty acid transport protein (FATP) and acyl CoA synthetase genes by PPARα and PPARγ activators. J Biol Chem 1997; 272: 28210-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 28210-28217
-
-
Martin, G.1
Schoonjans, K.2
Lefebvre, A.3
Staels, B.4
Auwerx, J.5
-
38
-
-
0029791412
-
PPARα and PPARγ activators direct a tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, et al. PPARα and PPARγ activators direct a tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J 1996; 15: 5336-48.
-
(1996)
EMBO J
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
-
39
-
-
0032538538
-
Characterization of the murine fatty acid transport protein gene and its insulin response sequence
-
Hui TY, Frohnert BI, Smith AJ, Schaffer JE, Bernlohr DA. Characterization of the murine fatty acid transport protein gene and its insulin response sequence. J Biol Chem 1998; 273: 27420-9.
-
(1998)
J Biol Chem
, vol.273
, pp. 27420-27429
-
-
Hui, T.Y.1
Frohnert, B.I.2
Smith, A.J.3
Schaffer, J.E.4
Bernlohr, D.A.5
-
40
-
-
0030794057
-
Peroxisome proliferator-activated receptors, orphans with ligands and functions
-
Schoonjans K, Martin G, Staels B, Auwerx J. Peroxisome proliferator-activated receptors, orphans with ligands and functions. Curr Opin Lipidol 1997; 8: 159-66.
-
(1997)
Curr Opin Lipidol
, vol.8
, pp. 159-166
-
-
Schoonjans, K.1
Martin, G.2
Staels, B.3
Auwerx, J.4
-
42
-
-
0000113890
-
Thiazolidinediones repress ob gene expression via activation of PPARγ
-
De Vos P, Lefebvre AM, Miller SG, Guerro-Millo M, Wong K, Saladin R, et al. Thiazolidinediones repress ob gene expression via activation of PPARγ. J Clin Invest 1996; 98: 1004-9.
-
(1996)
J Clin Invest
, vol.98
, pp. 1004-1009
-
-
De Vos, P.1
Lefebvre, A.M.2
Miller, S.G.3
Guerro-Millo, M.4
Wong, K.5
Saladin, R.6
-
43
-
-
15844415080
-
Down-regulation of the expression of the obese gene by antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice
-
Zhang B, Graziano MP, Doebber TW, Leibwitz MD, White-Carrington S, Szalkowski DM, et al. Down-regulation of the expression of the obese gene by antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice. J Biol Chem 1996; 271: 9455-9.
-
(1996)
J Biol Chem
, vol.271
, pp. 9455-9459
-
-
Zhang, B.1
Graziano, M.P.2
Doebber, T.W.3
Leibwitz, M.D.4
White-Carrington, S.5
Szalkowski, D.M.6
-
44
-
-
0029894050
-
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
-
Kallen CB, Lazar MA. Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A 1996; 93: 5793-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5793-5796
-
-
Kallen, C.B.1
Lazar, M.A.2
-
45
-
-
0029972928
-
The adipocyte specific transcription factor, C/ EBPα modulates human ob gene expression
-
Miller SG, De Vos P, Guerre-Millo M, Wong K, Hermann T, Staels B, et al. The adipocyte specific transcription factor, C/ EBPα modulates human ob gene expression. Proc Natl Acad Sci U S A 1996; 93: 5507-11.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5507-5511
-
-
Miller, S.G.1
De Vos, P.2
Guerre-Millo, M.3
Wong, K.4
Hermann, T.5
Staels, B.6
-
46
-
-
0028849084
-
The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha
-
He Y, Chen H, Quon MJ, Reitman M. The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha. J Biol Chem 1995; 270: 28887-91.
-
(1995)
J Biol Chem
, vol.270
, pp. 28887-28891
-
-
He, Y.1
Chen, H.2
Quon, M.J.3
Reitman, M.4
-
47
-
-
0031051523
-
Functional antagonism between CCAAT/Enhancer binding protein-α and peroxisome proliferator-activated receptor-γ on the leptin promoter
-
Hollenberg AN, Susulic VS, Madura JP, Zhang B, Moller DE, Tontonoz P, et al. Functional antagonism between CCAAT/Enhancer binding protein-α and peroxisome proliferator-activated receptor-γ on the leptin promoter. J Biol Chem 1997; 272: 5283-90.
-
(1997)
J Biol Chem
, vol.272
, pp. 5283-5290
-
-
Hollenberg, A.N.1
Susulic, V.S.2
Madura, J.P.3
Zhang, B.4
Moller, D.E.5
Tontonoz, P.6
-
48
-
-
0022385114
-
A macrophage factor inhibits adipocyte gene expression: An in vitro model for cachexia
-
Torti FM, Dieckman B, Beutler B, Cerami A, Ringold GM. A macrophage factor inhibits adipocyte gene expression: an in vitro model for cachexia. Science 1985; 229: 867-9.
-
(1985)
Science
, vol.229
, pp. 867-869
-
-
Torti, F.M.1
Dieckman, B.2
Beutler, B.3
Cerami, A.4
Ringold, G.M.5
-
49
-
-
0023954297
-
Cachectin (tumor necrosis factor): A macrophage hormone governing cellular metabolism and inflammatory response
-
Beutler B, Cerami A. Cachectin (tumor necrosis factor): a macrophage hormone governing cellular metabolism and inflammatory response. Endocrine Rev 1988; 9: 57-66.
-
(1988)
Endocrine Rev
, vol.9
, pp. 57-66
-
-
Beutler, B.1
Cerami, A.2
-
50
-
-
0026717621
-
CCAAT/enhancer binding protein expression is rapidly extinguished in TA1 adipocyte cells treated with tumor necrosis factor
-
Williams PM, Chang DJ, Danesch U, Ringold GM, Heller RA. CCAAT/enhancer binding protein expression is rapidly extinguished in TA1 adipocyte cells treated with tumor necrosis factor. Mol Endocrinol 1992; 6: 1135-41.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 1135-1141
-
-
Williams, P.M.1
Chang, D.J.2
Danesch, U.3
Ringold, G.M.4
Heller, R.A.5
-
51
-
-
0026504540
-
Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/ enhancer binding protein (C/EBP)
-
Ron D, Brasier AR, McGehee REJ, Habener JF. Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/ enhancer binding protein (C/EBP). J Clin Invest 1992; 89: 223-33.
-
(1992)
J Clin Invest
, vol.89
, pp. 223-233
-
-
Ron, D.1
Brasier, A.R.2
McGehee, R.E.J.3
Habener, J.F.4
-
52
-
-
0030885575
-
Thiazolidinediones block tumor necrosis factor-α-induced inhibition of insulin signalling
-
Peraldi P, Xu M, Spiegelman BM. Thiazolidinediones block tumor necrosis factor-α-induced inhibition of insulin signalling. J Clin Invest 1997; 100: 1863-9.
-
(1997)
J Clin Invest
, vol.100
, pp. 1863-1869
-
-
Peraldi, P.1
Xu, M.2
Spiegelman, B.M.3
-
53
-
-
0027459878
-
Adipose tissue expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose tissue expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
54
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 1995; 95: 2409-15.
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
55
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α and obesity induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α and obesity induced insulin resistance. Science 1996; 271: 665-8.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
57
-
-
0030831977
-
Peroxisome proliferator activated receptor γ, CCAAT/enhancer binding protein α and cell cycle status regulate the commitment to adipocyte differentiation
-
Shao D, Lazar MA. Peroxisome proliferator activated receptor γ, CCAAT/enhancer binding protein α and cell cycle status regulate the commitment to adipocyte differentiation. J Biol Chem 1997; 272: 21473-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 21473-21478
-
-
Shao, D.1
Lazar, M.A.2
-
58
-
-
0027972524
-
Altered gene expression for tumor necrosis factor-α and its receptor during drug and dietary modulation of insulin resistance
-
Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS, et al. Altered gene expression for tumor necrosis factor-α and its receptor during drug and dietary modulation of insulin resistance. Endocrinology 1994; 134: 264-70.
-
(1994)
Endocrinology
, vol.134
, pp. 264-270
-
-
Hofmann, C.1
Lorenz, K.2
Braithwaite, S.S.3
Colca, J.R.4
Palazuk, B.J.5
Hotamisligil, G.S.6
-
59
-
-
0032520921
-
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
-
Okuno A, Tamemoto H, Tobe K, Veki K, Mori Y, Iwamoto K, et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 1998; 101: 1354-61.
-
(1998)
J Clin Invest
, vol.101
, pp. 1354-1361
-
-
Okuno, A.1
Tamemoto, H.2
Tobe, K.3
Veki, K.4
Mori, Y.5
Iwamoto, K.6
-
60
-
-
0029860791
-
Modulation of insulin activities by leptin
-
Cohen B, Novick D, Rubinstein M. Modulation of insulin activities by leptin. Science 1996; 274: 1185-8.
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
61
-
-
0040381066
-
Leptin impairs metabolic actions of insulin in isolated rat adipocytes
-
Muller G, Ertl J, Gerl M, Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 1997; 272: 10585-93.
-
(1997)
J Biol Chem
, vol.272
, pp. 10585-10593
-
-
Muller, G.1
Ertl, J.2
Gerl, M.3
Preibisch, G.4
-
62
-
-
0031567614
-
Leptin inhibits glycogen synthesis in isolated soleus muscle of obese (ob/ob) mice
-
Liu YL, Emilsson V, Cawthorne MA. Leptin inhibits glycogen synthesis in isolated soleus muscle of obese (ob/ob) mice. FEBS Lett 1997; 411: 351-5.
-
(1997)
FEBS Lett
, vol.411
, pp. 351-355
-
-
Liu, Y.L.1
Emilsson, V.2
Cawthorne, M.A.3
-
63
-
-
0032037738
-
PPARγ activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes
-
Martin G, Schoonjans K, Staels B, Auwerx J. PPARγ activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes. Atherosclerosis 1998; 137: 75-80.
-
(1998)
Atherosclerosis
, vol.137
, pp. 75-80
-
-
Martin, G.1
Schoonjans, K.2
Staels, B.3
Auwerx, J.4
-
64
-
-
0030811602
-
The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue availability in the rat
-
Oakes ND, Camilleri S, Furler SM, Chisholm DJ, Kraegen EW. The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue availability in the rat. Metabolism 1997; 46: 935-42.
-
(1997)
Metabolism
, vol.46
, pp. 935-942
-
-
Oakes, N.D.1
Camilleri, S.2
Furler, S.M.3
Chisholm, D.J.4
Kraegen, E.W.5
-
65
-
-
50549202600
-
The glucose-fatty acid cycle: Its role in insulin sensitivity and metabolic disturbances of diabetes mellitus
-
Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose-fatty acid cycle: its role in insulin sensitivity and metabolic disturbances of diabetes mellitus. Lancet 1961; I: 785-9.
-
(1961)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
66
-
-
0025945012
-
Insulin resistance: Mechanisms, syndromes, and implications
-
Moller DE, Flier JS. Insulin resistance: mechanisms, syndromes, and implications. N Engl J Med 1991; 325: 938-48.
-
(1991)
N Engl J Med
, vol.325
, pp. 938-948
-
-
Moller, D.E.1
Flier, J.S.2
-
67
-
-
0032532152
-
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: A model for congenital generalized lipodystrophy
-
Shimomura I, Hammer RE, Richardson JA, Ikemoto S, Bashmakov Y, Goldstein JL, et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: a model for congenital generalized lipodystrophy. Genes Dev 1998; 12: 3182-94.
-
(1998)
Genes Dev
, vol.12
, pp. 3182-3194
-
-
Shimomura, I.1
Hammer, R.E.2
Richardson, J.A.3
Ikemoto, S.4
Bashmakov, Y.5
Goldstein, J.L.6
-
68
-
-
0032532753
-
Life without fat: A transgenic mouse
-
Moitra J, Mason MM, Olive M, Krylov D, Gavrilova O, Marcus-Samuels B, et al. Life without fat: a transgenic mouse. Genes Dev 1998; 12: 3168-81.
-
(1998)
Genes Dev
, vol.12
, pp. 3168-3181
-
-
Moitra, J.1
Mason, M.M.2
Olive, M.3
Krylov, D.4
Gavrilova, O.5
Marcus-Samuels, B.6
-
69
-
-
0031441286
-
Troglitazone action is independent of adipose tissue
-
Burant CF, Sreenan S, Hirano K-I, Tai TA, Lohmiller J, Lukens J, et al. Troglitazone action is independent of adipose tissue. J Clin Invest 1997; 100: 2900-8.
-
(1997)
J Clin Invest
, vol.100
, pp. 2900-2908
-
-
Burant, C.F.1
Sreenan, S.2
Hirano, K.-I.3
Tai, T.A.4
Lohmiller, J.5
Lukens, J.6
-
70
-
-
0033049772
-
An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer
-
Gelman L, Fruchart J-C, Auwerx J. An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer. Cell Mol Life Sci 1999; 55: 932-43.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 932-943
-
-
Gelman, L.1
Fruchart, J.-C.2
Auwerx, J.3
-
71
-
-
0031595111
-
PPARγ induces the insulin dependent glucose transporter GLUT4 in absence of C/EBPα during the conversion of 3T3 fibroblast into adipocytes
-
Wu Z, Xie Y, Morrison RF, Bucher NLR, Farmer SR. PPARγ induces the insulin dependent glucose transporter GLUT4 in absence of C/EBPα during the conversion of 3T3 fibroblast into adipocytes. J Clin Invest 1998; 101: 22-32.
-
(1998)
J Clin Invest
, vol.101
, pp. 22-32
-
-
Wu, Z.1
Xie, Y.2
Morrison, R.F.3
Bucher, N.L.R.4
Farmer, S.R.5
-
72
-
-
0032409985
-
Thiazolidinediones and insulin resistance: Peroxisome proliferator-activated receptor γ activation stimulates expression of the CAP gene
-
Ribon V, Johnson JH, Camp HS, Saltiel AR. Thiazolidinediones and insulin resistance: peroxisome proliferator-activated receptor γ activation stimulates expression of the CAP gene. Proc Natl Acad Sci U S A 1998; 95: 14751-6.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14751-14756
-
-
Ribon, V.1
Johnson, J.H.2
Camp, H.S.3
Saltiel, A.R.4
-
74
-
-
0030967953
-
Predicting obesity in young adulthood from childhood and parental obesity
-
Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med 1997; 337: 869-73.
-
(1997)
N Engl J Med
, vol.337
, pp. 869-873
-
-
Whitaker, R.C.1
Wright, J.A.2
Pepe, M.S.3
Seidel, K.D.4
Dietz, W.H.5
-
75
-
-
0031914386
-
Human peroxisome proliferator-activated receptor-gamma2: Genetic mapping, identification of a variant in the coding sequence, and exclusion as the gene responsible for lipoatrophic diabetes
-
Vigouroux C, Fajas L, Khallouf E, Meier M, Gyapay G, Lascols O, et al. Human peroxisome proliferator-activated receptor-gamma2: genetic mapping, identification of a variant in the coding sequence, and exclusion as the gene responsible for lipoatrophic diabetes. Diabetes 1998; 47: 490-2.
-
(1998)
Diabetes
, vol.47
, pp. 490-492
-
-
Vigouroux, C.1
Fajas, L.2
Khallouf, E.3
Meier, M.4
Gyapay, G.5
Lascols, O.6
-
76
-
-
0032189782
-
Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
-
Ristow M, Muller-Wieland D, Pfeiffer A, Krone W, Kahn CR. Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N Engl J Med 1998; 339: 953-9.
-
(1998)
N Engl J Med
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Muller-Wieland, D.2
Pfeiffer, A.3
Krone, W.4
Kahn, C.R.5
-
77
-
-
0345164399
-
Molecular scanning of the human peroxisome proliferator activated receptor gamma gene in diabetic Caucasians: Identification of a Prol2Ala PPARgamma 2 missense mutation
-
Yen CJ, Beamer BA, Negri C, Silver K, Brown KA, Yarnall DP, et al. Molecular scanning of the human peroxisome proliferator activated receptor gamma gene in diabetic Caucasians: identification of a Prol2Ala PPARgamma 2 missense mutation. Biochem Biophys Res Commun 1997; 241: 270-4.
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 270-274
-
-
Yen, C.J.1
Beamer, B.A.2
Negri, C.3
Silver, K.4
Brown, K.A.5
Yarnall, D.P.6
-
78
-
-
0031595923
-
A Pro 12 Ala substitution in the human peroxisome proliferator-activated receptor gamma2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index
-
Deeb S, Fajas L, Nemoto M, Laakso M, Fujimoto W, Auwerx J. A Pro 12 Ala substitution in the human peroxisome proliferator-activated receptor gamma2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index. Nat Genet 1998; 20: 284-7.
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.1
Fajas, L.2
Nemoto, M.3
Laakso, M.4
Fujimoto, W.5
Auwerx, J.6
-
79
-
-
0031667127
-
Association of the Prol2Ala variant in peroxisome proliferator-activated receptor gamma2 gene with obesity in two Caucasian populations
-
Beamer BA, Yen CJ, Andersen RE, Muller D, Elahi D, Cheskin LJ, et al. Association of the Prol2Ala variant in peroxisome proliferator-activated receptor gamma2 gene with obesity in two Caucasian populations. Diabetes 1998; 47: 1806-8.
-
(1998)
Diabetes
, vol.47
, pp. 1806-1808
-
-
Beamer, B.A.1
Yen, C.J.2
Andersen, R.E.3
Muller, D.4
Elahi, D.5
Cheskin, L.J.6
-
80
-
-
0032500747
-
Effect of the Prol2Ala variant of the human peroxisome proliferator activated receptor γ2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men
-
Mori Y, Kim-Motoyama H, Katakura T, Yasuda K, Kadowaki H, Beamer BA, et al. Effect of the Prol2Ala variant of the human peroxisome proliferator activated receptor γ2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men. Biochem Biophys Res Commun 1998; 251: 195-8.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 195-198
-
-
Mori, Y.1
Kim-Motoyama, H.2
Katakura, T.3
Yasuda, K.4
Kadowaki, H.5
Beamer, B.A.6
-
81
-
-
0032781890
-
Homozygosity of the Prol2Ala variant of the peroxisome proliferator activated receptor γ2 (PPARγ2): Divergent modulating effects on body mass index in obese and lean men of Caucasian origin
-
Ek J, Urhammer SA, Sorensen TIA, Andersen T, Auwerx J, Pedersen O. Homozygosity of the Prol2Ala variant of the peroxisome proliferator activated receptor γ2 (PPARγ2): divergent modulating effects on body mass index in obese and lean men of Caucasian origin. Diabetologia 1999; 42: 892-5.
-
(1999)
Diabetologia
, vol.42
, pp. 892-895
-
-
Ek, J.1
Urhammer, S.A.2
Sorensen, T.I.A.3
Andersen, T.4
Auwerx, J.5
Pedersen, O.6
-
82
-
-
0030877565
-
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ). Differential activity of PPAR γ1 and -2 isoforms and influence of insulin
-
Werman A, Hollenberg A, Solanes G, Bjorbaek C, Vidal-Pulg A, Flier JS. Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ). Differential activity of PPAR γ1 and -2 isoforms and influence of insulin. J Biol Chem 1997; 272: 20230-5.
-
(1997)
J Biol Chem
, vol.272
, pp. 20230-20235
-
-
Werman, A.1
Hollenberg, A.2
Solanes, G.3
Bjorbaek, C.4
Vidal-Pulg, A.5
Flier, J.S.6
-
83
-
-
0033583023
-
p300 interacts with the N- and C-terminal part of PPARγ2 in a ligand-independent and -dependent manner, respectively
-
Gelman L, Zhou G, Fajas L, Raspe E, Fruchart JC, Auwerx J. p300 interacts with the N- and C-terminal part of PPARγ2 in a ligand-independent and -dependent manner, respectively. J Biol Chem 1999; 274: 7681-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 7681-7688
-
-
Gelman, L.1
Zhou, G.2
Fajas, L.3
Raspe, E.4
Fruchart, J.C.5
Auwerx, J.6
-
84
-
-
0032569902
-
Interdomain communication regulating ligand binding by PPAR gamma
-
Shao D, Rangwala SM, Bailey ST, Krakow SL, Reginato MJ, Lazar MA. Interdomain communication regulating ligand binding by PPAR gamma. Nature 1998; 396: 377-80.
-
(1998)
Nature
, vol.396
, pp. 377-380
-
-
Shao, D.1
Rangwala, S.M.2
Bailey, S.T.3
Krakow, S.L.4
Reginato, M.J.5
Lazar, M.A.6
-
85
-
-
0029823459
-
Lipid mediator networks in cell signaling: Update and impact of cytokines
-
Serhan CN, Haeggstrom JZ, Leslie CC. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J 1996; 10: 1147-58.
-
(1996)
FASEB J
, vol.10
, pp. 1147-1158
-
-
Serhan, C.N.1
Haeggstrom, J.Z.2
Leslie, C.C.3
-
86
-
-
0031888958
-
PPARγ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B. PPARγ agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391: 82-6.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
87
-
-
0031886864
-
The peroxisome proliferator-activated receptor γ is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor γ is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
88
-
-
0031013395
-
Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, Kliewer SA. Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1997; 272: 3406-10.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
89
-
-
0029152375
-
Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
-
Greene ME, Blumberg B, McBride OW, Yi HF, Kronquist K, Kwan K, et al. Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expression 1995; 4: 281-99.
-
(1995)
Gene Expression
, vol.4
, pp. 281-299
-
-
Greene, M.E.1
Blumberg, B.2
McBride, O.W.3
Yi, H.F.4
Kronquist, K.5
Kwan, K.6
-
90
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy L, Tontonez P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 1998; 93: 229-40.
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonez, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
91
-
-
0031870652
-
Macrophages in human atheroma contain PPARgamma: Differentiation-dependent PPARgamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
-
Marx N, Sukhova G, Murphy C, Libby P, Plutzky J. Macrophages in human atheroma contain PPARgamma: differentiation-dependent PPARgamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am J Pathol 1998; 153: 17-23.
-
(1998)
Am J Pathol
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
92
-
-
0344333464
-
Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells
-
Marx N, Schoenbeck U, Lazar MA, Libby P, Plutzky J. Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res 1998; 83: 1097-103.
-
(1998)
Circ Res
, vol.83
, pp. 1097-1103
-
-
Marx, N.1
Schoenbeck, U.2
Lazar, M.A.3
Libby, P.4
Plutzky, J.5
-
93
-
-
0032540013
-
PPARgamma in monocytes: Less pain, any gain?
-
Spiegelman BM. PPARgamma in monocytes: less pain, any gain? Cell 1998; 93: 153-5.
-
(1998)
Cell
, vol.93
, pp. 153-155
-
-
Spiegelman, B.M.1
-
94
-
-
0030612740
-
PPARγ induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
-
Altiek S, Xu M, Spiegelman B. PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev 1997; 11: 1987-98.
-
(1997)
Genes Dev
, vol.11
, pp. 1987-1998
-
-
Altiek, S.1
Xu, M.2
Spiegelman, B.3
-
95
-
-
0033593231
-
Activation of peroxisome proliferator activated receptor γ bypasses the function of the retinoblastoma protein in adipocyte differentiation
-
Hansen JB, Petersen RK, Larsen BM, Bartkova J, Alsner J, Kristiansen K. Activation of peroxisome proliferator activated receptor γ bypasses the function of the retinoblastoma protein in adipocyte differentiation. J Biol Chem 1999; 274: 2386-93.
-
(1999)
J Biol Chem
, vol.274
, pp. 2386-2393
-
-
Hansen, J.B.1
Petersen, R.K.2
Larsen, B.M.3
Bartkova, J.4
Alsner, J.5
Kristiansen, K.6
-
96
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor
-
Tontonoz P, Singer S, Forman BM, Sarraf P, Fletcher JA, Fletcher DC, et al. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proc Natl Acad Sci U S A 1997; 94: 237-41.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
Sarraf, P.4
Fletcher, J.A.5
Fletcher, D.C.6
-
97
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, et al. Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 1998; 95: 8806-11.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
Williamson, E.A.4
Park, D.5
Asou, H.6
-
98
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPARγ
-
Mueller E, Sarraf P, Tontonoz P, Evans RM, Martin KJ, Zhang M, et al. Terminal differentiation of human breast cancer through PPARγ. Mol Cell 1998; 1: 465-70.
-
(1998)
Mol Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
-
99
-
-
0031595670
-
Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells
-
Brockman JA, Gupta RA, DuBois RN. Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 1998; 115: 1049-55.
-
(1998)
Gastroenterology
, vol.115
, pp. 1049-1055
-
-
Brockman, J.A.1
Gupta, R.A.2
DuBois, R.N.3
-
100
-
-
0032145363
-
Ligand for peroxisome proliferator activated receptor γ (troglitazone) has potent anti-tumor effects against human prostate cancer both in vitro and in vivo
-
Kubota T, Koshizaka K, Williamson EA, Asou H, Said JW, Holden S, et al. Ligand for peroxisome proliferator activated receptor γ (troglitazone) has potent anti-tumor effects against human prostate cancer both in vitro and in vivo. Cancer Res 1998; 58: 3344-52.
-
(1998)
Cancer Res
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
Koshizaka, K.2
Williamson, E.A.3
Asou, H.4
Said, J.W.5
Holden, S.6
-
102
-
-
0031667938
-
Activators of the nuclear receptor PPARγ enhance colon polyp formation
-
Saez E, Tontonoz P, Nelson MC, Alvarez JG, Ming UT, Baird SM, et al. Activators of the nuclear receptor PPARγ enhance colon polyp formation. Nat Med 1998; 4: 1058-61.
-
(1998)
Nat Med
, vol.4
, pp. 1058-1061
-
-
Saez, E.1
Tontonoz, P.2
Nelson, M.C.3
Alvarez, J.G.4
Ming, U.T.5
Baird, S.M.6
-
103
-
-
0030592517
-
Lessons from heriditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from heriditary colorectal cancer. Cell 1996; 87: 159-70.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
104
-
-
0029949369
-
Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonie mucosa
-
Mansen A, Guardiola-Diaz H, Rafter J, Branting C, Gustafsson JA. Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonie mucosa. Biochem Biophys Res Commun 1996; 222: 844-51.
-
(1996)
Biochem Biophys Res Commun
, vol.222
, pp. 844-851
-
-
Mansen, A.1
Guardiola-Diaz, H.2
Rafter, J.3
Branting, C.4
Gustafsson, J.A.5
-
105
-
-
0028576901
-
Dietary factors and risk of colon cancer
-
Giovanucci E, Willet WC. Dietary factors and risk of colon cancer. Ann Med 1994; 26: 443-52.
-
(1994)
Ann Med
, vol.26
, pp. 443-452
-
-
Giovanucci, E.1
Willet, W.C.2
-
106
-
-
0030903037
-
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice
-
Wasan HS, Novelli M, Bee J, Bodmer WF. Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proc Natl Acad Sci U S A 1997; 94: 3308-13.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3308-3313
-
-
Wasan, H.S.1
Novelli, M.2
Bee, J.3
Bodmer, W.F.4
-
107
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
Sarraf P, Mueller E, Jones D, King FJ, DeAngelo DJ, Partridge JB, et al. Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat Med 1998; 4: 1046-52.
-
(1998)
Nat Med
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
King, F.J.4
DeAngelo, D.J.5
Partridge, J.B.6
|