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Volumn 83, Issue 11, 1998, Pages 1097-1103

Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells

Author keywords

Gene expression; Migration; Peroxisome proliferator activated receptor gamma; Troglitazone; Vascular smooth muscle cell

Indexed keywords

15 DEOXY 12,14 PROSTAGLANDIN J2; GELATINASE B; MATRIX METALLOPROTEINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; TROGLITAZONE; UNCLASSIFIED DRUG;

EID: 0344333464     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.11.1097     Document Type: Article
Times cited : (566)

References (34)
  • 1
    • 0028237165 scopus 로고
    • Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix degradation
    • Galis Z, Muszynski M, Sukhova G, Simon-Morrissey E, Unemori E, Lark M, Amento E, Libby P. Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix degradation. Circ Res. 1994;75:181-189.
    • (1994) Circ Res. , vol.75 , pp. 181-189
    • Galis, Z.1    Muszynski, M.2    Sukhova, G.3    Simon-Morrissey, E.4    Unemori, E.5    Lark, M.6    Amento, E.7    Libby, P.8
  • 2
    • 0028146228 scopus 로고
    • Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat
    • Bendeck M, Zempo N, Clowes A, Galardy R, Reidy M. Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. Circ Res. 1994;75:539-545.
    • (1994) Circ Res. , vol.75 , pp. 539-545
    • Bendeck, M.1    Zempo, N.2    Clowes, A.3    Galardy, R.4    Reidy, M.5
  • 3
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis Z, Sukhova G, Lark M, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest. 1994;94:2493-2503.
    • (1994) J Clin Invest. , vol.94 , pp. 2493-2503
    • Galis, Z.1    Sukhova, G.2    Lark, M.3    Libby, P.4
  • 4
    • 0028906790 scopus 로고
    • Identification of 92 kD gelatinase in human coronary atherosclerotic lesions
    • Brown DL, Hibbs MS, Kearney M, Loushin C, Isner JM. Identification of 92 kD gelatinase in human coronary atherosclerotic lesions. Circulation. 1995;91:2125-2131.
    • (1995) Circulation. , vol.91 , pp. 2125-2131
    • Brown, D.L.1    Hibbs, M.S.2    Kearney, M.3    Loushin, C.4    Isner, J.M.5
  • 5
    • 0029862599 scopus 로고    scopus 로고
    • Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells
    • Fabunmi RP, Baker AH, Murray EJ, Booth RF, Newby AC. Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells. Biochem J. 1996;315:335-342.
    • (1996) Biochem J. , vol.315 , pp. 335-342
    • Fabunmi, R.P.1    Baker, A.H.2    Murray, E.J.3    Booth, R.F.4    Newby, A.C.5
  • 6
    • 0342872046 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes
    • Schönbeck U, Mach F, Sukhova G, Murphy C, Bonnefoy J-Y, Fabunmi R, Libby P. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes. Circ Res. 1997;81: 448-454.
    • (1997) Circ Res. , vol.81 , pp. 448-454
    • Schönbeck, U.1    Mach, F.2    Sukhova, G.3    Murphy, C.4    Bonnefoy, J.-Y.5    Fabunmi, R.6    Libby, P.7
  • 8
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 1995;270:12953-12956.
    • (1995) J Biol Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 9
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: Alternative promotor use and different splicing yield two mPPARy isoforms
    • Zhu Y, Qi C, Korenberg J, Chen X, Noya D, Rao M, Reddy J. Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: alternative promotor use and different splicing yield two mPPARy isoforms. Proc Natl Acad Sci U S A. 1995;92:7921-7925.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenberg, J.3    Chen, X.4    Noya, D.5    Rao, M.6    Reddy, J.7
  • 10
    • 0029791412 scopus 로고    scopus 로고
    • PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans K, Peinado-Onsurbe J, Lefebvre A, Deeb S, Staels B, Auwerx J. PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 1996;15:5336-5348.
    • (1996) EMBO J. , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.3    Deeb, S.4    Staels, B.5    Auwerx, J.6
  • 11
    • 0030794057 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors, orphans with ligands and functions
    • Schoonjans K, Martin G, Staels B, Auwerx J. Peroxisome proliferator-activated receptors, orphans with ligands and functions. Curr Opin Lipidol. 1997;8:159-166.
    • (1997) Curr Opin Lipidol. , vol.8 , pp. 159-166
    • Schoonjans, K.1    Martin, G.2    Staels, B.3    Auwerx, J.4
  • 15
    • 0031870652 scopus 로고    scopus 로고
    • Macrophages in human atheroma contain PPARγ: Differentiation-dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes
    • Marx N, Sukhova G, Murphy C, Libby P, Plutzky J. Macrophages in human atheroma contain PPARγ: differentiation-dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes. Am J Pathol. 1998;153:17-23.
    • (1998) Am J Pathol. , vol.153 , pp. 17-23
    • Marx, N.1    Sukhova, G.2    Murphy, C.3    Libby, P.4    Plutzky, J.5
  • 16
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1998;95:7614-7619.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6    Witztum, J.L.7    Auwerx, J.8    Palinski, W.9    Glass, C.K.10
  • 17
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature. 1998;391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 18
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998;391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 19
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 1998;93:241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 20
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 1998;93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 22
    • 0031939716 scopus 로고    scopus 로고
    • Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma
    • Reginato MJ, Krakow SL, Bailey ST, Lazar MA. Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma. J Biol Chem. 1998;273: 1855-1858.
    • (1998) J Biol Chem. , vol.273 , pp. 1855-1858
    • Reginato, M.J.1    Krakow, S.L.2    Bailey, S.T.3    Lazar, M.A.4
  • 24
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • 22a. Keller H, Dreyer C, Medin J, Mahfoudi A, Ozato K, Wahli W. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci U S A. 1993;90:2160-2164.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 25
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
    • Vu-Dac N, Schoonjans K, Laine B, Fruchart J, Auwerx J, Staels B. Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J Biol Chem. 1994;269: 31012-31018.
    • (1994) J Biol Chem. , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.4    Auwerx, J.5    Staels, B.6
  • 27
    • 0027521592 scopus 로고
    • Nuclear receptor/AP-1 interaction
    • Pfahl M. Nuclear receptor/AP-1 interaction. Endocr Rev. 1993;14: 651-658.
    • (1993) Endocr Rev. , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 28
    • 0031037988 scopus 로고    scopus 로고
    • Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription
    • Schwarz E, Reginato M, Shao D, Krakow S, Lazar M. Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription. Mol Cell Biol. 1997;17:1552-1561.
    • (1997) Mol Cell Biol. , vol.17 , pp. 1552-1561
    • Schwarz, E.1    Reginato, M.2    Shao, D.3    Krakow, S.4    Lazar, M.5
  • 30
    • 0020520943 scopus 로고
    • Kinetics of cellular proliferation after arterial injury, I: Smooth muscle growth in the absence of endothelium
    • Clowes AW, Reidy MA, Clowes MM. Kinetics of cellular proliferation after arterial injury, I: smooth muscle growth in the absence of endothelium. Lab Invest. 1983;49:327-333.
    • (1983) Lab Invest. , vol.49 , pp. 327-333
    • Clowes, A.W.1    Reidy, M.A.2    Clowes, M.M.3
  • 32
    • 0031764885 scopus 로고    scopus 로고
    • Another potential use of troglitazone in non-insulin dependent diabetes mellitus
    • Minamikawa J, Yamauchi M, Innoue D, Koshiyama H. Another potential use of troglitazone in non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1998;83:1041-1042.
    • (1998) J Clin Endocrinol Metab. , vol.83 , pp. 1041-1042
    • Minamikawa, J.1    Yamauchi, M.2    Innoue, D.3    Koshiyama, H.4
  • 33
    • 0032568310 scopus 로고    scopus 로고
    • Effect of troglitazone in insulin-treated patients with type II diabetes mellitus
    • Schwartz S, Raskin P, Fonseca V, Graveline J. Effect of troglitazone in insulin-treated patients with type II diabetes mellitus. N Engl J Med. 1998;338:861-866.
    • (1998) N Engl J Med. , vol.338 , pp. 861-866
    • Schwartz, S.1    Raskin, P.2    Fonseca, V.3    Graveline, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.