-
1
-
-
0029081813
-
Severe obesity: Expensive to society, frustrating to treat, but important to confront
-
Martin, L. F., Hunter, S. M., Lauve, R. M., and O'Leary, J. P. Severe obesity: expensive to society, frustrating to treat, but important to confront. Southern Med. J., 88: 895-902, 1995.
-
(1995)
Southern Med. J.
, vol.88
, pp. 895-902
-
-
Martin, L.F.1
Hunter, S.M.2
Lauve, R.M.3
O'Leary, J.P.4
-
2
-
-
0015163467
-
Adipose cellularity in relation to human adiposity
-
G. H. Stollerman (ed.), Chicago: Year Book Medical Publishers
-
Hirsch, J. Adipose cellularity in relation to human adiposity. In: G. H. Stollerman (ed.), Advances in Internal Medicine, Vol. 17, pp. 289-300. Chicago: Year Book Medical Publishers, 1971.
-
(1971)
Advances in Internal Medicine
, vol.17
, pp. 289-300
-
-
Hirsch, J.1
-
3
-
-
0028015802
-
Regulation of adipocyte development
-
Cornelius, P., MacDouglad, O. A., and Lane, M. D. Regulation of adipocyte development. Annu. Rev. Nutr., 14: 99-129, 1994.
-
(1994)
Annu. Rev. Nutr.
, vol.14
, pp. 99-129
-
-
Cornelius, P.1
MacDouglad, O.A.2
Lane, M.D.3
-
4
-
-
0031037111
-
Regulation of adipose cell number in man
-
Prins, J. B., and O'Rahilly, S. Regulation of adipose cell number in man. Clin. Sci., 92: 3-11, 1997.
-
(1997)
Clin. Sci.
, vol.92
, pp. 3-11
-
-
Prins, J.B.1
O'Rahilly, S.2
-
5
-
-
0019299222
-
Expression of insulin receptors during preadipocyte differentiation
-
Reed, B. C., and Lane, M. D. Expression of insulin receptors during preadipocyte differentiation. Adv. Enzyme. Regul., 18: 97-117, 1980.
-
(1980)
Adv. Enzyme. Regul.
, vol.18
, pp. 97-117
-
-
Reed, B.C.1
Lane, M.D.2
-
6
-
-
0023124010
-
Differentiation of human adipocyte precursors in a chemically defined serum-free medium
-
Deslex, S., Negrel, R., Vannier, C., Etienne, J., and Ailhaud, G. Differentiation of human adipocyte precursors in a chemically defined serum-free medium. Int. J. Obesity, 11: 19-27, 1986.
-
(1986)
Int. J. Obesity
, vol.11
, pp. 19-27
-
-
Deslex, S.1
Negrel, R.2
Vannier, C.3
Etienne, J.4
Ailhaud, G.5
-
7
-
-
0032054230
-
Transcriptional control of adipogenesis
-
in press
-
Fajas, L., Fruchart, J. C., and Auwerx, J. Transcriptional control of adipogenesis. Curr. Opin. Cell Biol., in press, 1999.
-
(1999)
Curr. Opin. Cell Biol.
-
-
Fajas, L.1
Fruchart, J.C.2
Auwerx, J.3
-
8
-
-
0031041075
-
Regulating adipogenesis
-
Mandrup, S., and Lane, M. D. Regulating adipogenesis. J. Biol. Chem., 272: 5367-5370, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5367-5370
-
-
Mandrup, S.1
Lane, M.D.2
-
9
-
-
0029318530
-
Adipocyte differentiation. When precursors are also regulators
-
MacDouglad, O. A., and Lane, M. D. Adipocyte differentiation. When precursors are also regulators. Curr. Biol., 5: 618-621, 1995.
-
(1995)
Curr. Biol.
, vol.5
, pp. 618-621
-
-
MacDouglad, O.A.1
Lane, M.D.2
-
10
-
-
0028878375
-
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
-
Yeh, W. C., Cao, Z., Classon, M., and McKnight, L. M. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev., 9: 168-181, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 168-181
-
-
Yeh, W.C.1
Cao, Z.2
Classon, M.3
McKnight, L.M.4
-
11
-
-
0028129499
-
Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells
-
Freytag, S. O., Paielli, D. L., and Gilbert, J. D. Ectopic expression of the CCAAT/enhancer-binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev., 8: 1654-1663, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 1654-1663
-
-
Freytag, S.O.1
Paielli, D.L.2
Gilbert, J.D.3
-
12
-
-
0030831977
-
Peroxisome proliferator activated receptor γ, CCAAT/enhancer-binding protein α, and cell cycle status regulate the commitment to adipocyte differentiation
-
Shao, D., and Lazar, M. A. Peroxisome proliferator activated receptor γ, CCAAT/enhancer-binding protein α, and cell cycle status regulate the commitment to adipocyte differentiation. J. Biol. Chem., 272: 21473-21478, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21473-21478
-
-
Shao, D.1
Lazar, M.A.2
-
13
-
-
0030007427
-
ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
-
Kim, J., and Spiegelman, B. M. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev., 10: 1096-1107, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 1096-1107
-
-
Kim, J.1
Spiegelman, B.M.2
-
14
-
-
0029981772
-
Differential activation of adipogenesis by multiple PPAR isoforms
-
Brun, R. P., Tontonoz, P., Forman, B. M., Ellis, R., Chen, J., Evans, R. M., and Spiegelman, B. M. Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev., 10: 974-984, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 974-984
-
-
Brun, R.P.1
Tontonoz, P.2
Forman, B.M.3
Ellis, R.4
Chen, J.5
Evans, R.M.6
Spiegelman, B.M.7
-
15
-
-
0028180070
-
mPPARγ2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz, P., Hu, E., Graves, R. A., Budavari, A. I., and Spiegelman, B. M. mPPARγ2: tissue-specific regulator of an adipocyte enhancer. Genes Dev., 8: 1224-1234, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
16
-
-
0028641559
-
Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ
-
Tontonoz, P., Hu, E., and Spiegelman, B. M. Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ. Cell, 79: 1147-1156, 1994.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
17
-
-
0027749599
-
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
-
Zhu, Y., Alvares, K., Huang, Q., Rao, M. S., and Reddy, J. K. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J. Biol. Chem., 268: 26817-26820, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26817-26820
-
-
Zhu, Y.1
Alvares, K.2
Huang, Q.3
Rao, M.S.4
Reddy, J.K.5
-
18
-
-
0030951143
-
Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARγ2 versus PPARγ1, and activation with retinoid X receptor agonists, and antagonists
-
Mukherjee, R., Jow, L., Croston, G. E., and Paterniti, J. R., Jr. Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARγ2 versus PPARγ1, and activation with retinoid X receptor agonists, and antagonists. J. Biol. Chem., 272: 8071-8076, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8071-8076
-
-
Mukherjee, R.1
Jow, L.2
Croston, G.E.3
Paterniti J.R., Jr.4
-
19
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARγ gene
-
Fajas, L., Auboeuf, D., Raspé, E., Schoonjans, K., Lefebvre, A. M., Saladin, R., Najib, J., Laville, M., Fruchart, J. C., Deeb, S., Vidal-Puig, A., Flier, J., Briggs, M. R., Staels, B., Vidal, H., and Auwerx, J. The organization, promoter analysis, and expression of the human PPARγ gene. J. Biol. Chem., 272: 18779-18789, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspé, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
20
-
-
0030977450
-
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Puig, A. J., Considine, R. V., Jimenez-Linan, M., Werman, A., Pories, W. J., Caro, J. F., and Flier, J. S. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J. Clin. Invest., 99: 2416-2422, 1997.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2416-2422
-
-
Vidal-Puig, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
Werman, A.4
Pories, W.J.5
Caro, J.F.6
Flier, J.S.7
-
21
-
-
0030877565
-
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ)
-
Werman, A., Hollenberg, A., Solanes, G., Bjørbaek, C., Vidal-Puig, A. J., and Flier, J. S. Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ). J. Biol. Chem., 272: 20230-20235, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20230-20235
-
-
Werman, A.1
Hollenberg, A.2
Solanes, G.3
Bjørbaek, C.4
Vidal-Puig, A.J.5
Flier, J.S.6
-
22
-
-
0030612740
-
PPARγ induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
-
Altiok, S., Xu, M., and Spiegelman, B. M. PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev., 11: 1987-1998, 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 1987-1998
-
-
Altiok, S.1
Xu, M.2
Spiegelman, B.M.3
-
23
-
-
0029994543
-
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
-
Schoonjans, K., Staels, B., and Auwerx, J. Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res., 37: 907-925, 1996.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 907-925
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
24
-
-
0028202490
-
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival
-
Chawla, A., and Lazar, M. A. Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. Proc. Natl. Acad. Sci. USA, 91: 1786-1790, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1786-1790
-
-
Chawla, A.1
Lazar, M.A.2
-
25
-
-
0029919647
-
Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ
-
Xue, J. C., Schwarz, E. J., Chawla, A., and Lazar, M. A. Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ. Mol. Cell. Biol., 16: 1567-1575, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1567-1575
-
-
Xue, J.C.1
Schwarz, E.J.2
Chawla, A.3
Lazar, M.A.4
-
26
-
-
1842295133
-
Peroxisome proliferator-activated receptor and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corepressors
-
DiRenzo, J., Sàderstràm, M., Kurokawa, R., Ogliastro, M. H., Ricote, M., Ingrey, S., Hörlein, A., Rosenfeld, M. G., and Glass, C. K. Peroxisome proliferator-activated receptor and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corepressors. Mol. Cell. Biol., 17: 2166-2176, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2166-2176
-
-
DiRenzo, J.1
Sàderstràm, M.2
Kurokawa, R.3
Ogliastro, M.H.4
Ricote, M.5
Ingrey, S.6
Hörlein, A.7
Rosenfeld, M.G.8
Glass, C.K.9
-
27
-
-
0029102817
-
cAMP activation of CAAT enhancer-binding protein-β gene expression and promoter I of acetyl-CoA carboxylase
-
Tae, H. J., Zhang, S., and Kim, K. H. cAMP activation of CAAT enhancer-binding protein-β gene expression and promoter I of acetyl-CoA carboxylase. J. Biol. Chem., 270: 21487-21494, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21487-21494
-
-
Tae, H.J.1
Zhang, S.2
Kim, K.H.3
-
28
-
-
0026050219
-
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
-
Cao, Z., Umek, R., and McKnight, S. L. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev., 5: 1538-1542, 1991.
-
(1991)
Genes Dev.
, vol.5
, pp. 1538-1542
-
-
Cao, Z.1
Umek, R.2
McKnight, S.L.3
-
29
-
-
0028971225
-
Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis
-
Wu, Z., Xie, Y., Bucher, N. L. R., and Farmer, S. R. Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis. Genes Dev., 9: 2350-2363, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 2350-2363
-
-
Wu, Z.1
Xie, Y.2
Bucher, N.L.R.3
Farmer, S.R.4
-
30
-
-
0031558772
-
CAAT/enhancer binding proteins directly modulate transcription from the peraxisome proliferator-activated receptor γ2 promoter
-
Clarke, S. L., Robinson, C. E., and Gimble, J. M. CAAT/enhancer binding proteins directly modulate transcription from the peraxisome proliferator-activated receptor γ2 promoter. Biochem. Biophys. Res. Commun., 240: 99-103, 1997.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 99-103
-
-
Clarke, S.L.1
Robinson, C.E.2
Gimble, J.M.3
-
31
-
-
0032516081
-
AAD1/SREBP-1 activates PPARγ through the production of endogenous ligand
-
Kim, J. B., Wright, H. M., Wright, M., and Spiegelman, B. M. AAD1/SREBP-1 activates PPARγ through the production of endogenous ligand. Proc. Natl. Acad. Sci. USA, 95: 4333-4337, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4333-4337
-
-
Kim, J.B.1
Wright, H.M.2
Wright, M.3
Spiegelman, B.M.4
-
32
-
-
0027405166
-
Tumor necrosis factor-α prevents the differentiation of human adipocyte precursor cells and causes delipidation of newly developed fat cells
-
Petruschke, T. H., and Hauner, H. Tumor necrosis factor-α prevents the differentiation of human adipocyte precursor cells and causes delipidation of newly developed fat cells. J. Clin. Endocrinol. Metab., 76: 742-747, 1993.
-
(1993)
J. Clin. Endocrinol. Metab.
, vol.76
, pp. 742-747
-
-
Petruschke, T.H.1
Hauner, H.2
-
33
-
-
0029157428
-
Transient increase in obese gene expression after food intake or insulin administration
-
Lond.
-
Saladin, R., De Vos, P., Guerre-Millo, M., Leturque, A., Girard, J., Staels, B., and Auwerx, J. Transient increase in obese gene expression after food intake or insulin administration. Nature (Lond.), 377: 527-529, 1995.
-
(1995)
Nature
, vol.377
, pp. 527-529
-
-
Saladin, R.1
De Vos, P.2
Guerre-Millo, M.3
Leturque, A.4
Girard, J.5
Staels, B.6
Auwerx, J.7
-
34
-
-
0030037364
-
Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle
-
Laville, M., Auboeuf, D., Khalfallah, Y., Vega, N., Riou, J. P., and Vidal, H. Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle. J. Clin. Invest., 98: 43-49, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 43-49
-
-
Laville, M.1
Auboeuf, D.2
Khalfallah, Y.3
Vega, N.4
Riou, J.P.5
Vidal, H.6
-
35
-
-
0030747895
-
Tissue distribution and quantification of the expression of PPARs and LXRa in humans: No alterations in adipose tissue of obese and NIDDM patients
-
Auboeuf, D., Rieusset, J., Fajas, L., Vallier, P., Frering, V., Riou, J. P., Staels, B., Auwerx, J., Laville, M., and Vidal, H. Tissue distribution and quantification of the expression of PPARs and LXRa in humans: no alterations in adipose tissue of obese and NIDDM patients. Diabetes, 46: 1319-1327, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
36
-
-
0027440945
-
Nuclear hormone receptors as targets for new drug discovery
-
McDonnell, D. P., Vegeto, E., and Gleeson M. A. G. Nuclear hormone receptors as targets for new drug discovery. Bio/Technology, 11: 1256-1261, 1993.
-
(1993)
Bio/Technology
, vol.11
, pp. 1256-1261
-
-
McDonnell, D.P.1
Vegeto, E.2
Gleeson, M.A.G.3
|