ATM directs DNA damage responses and proteostasis via genetically separable pathways

Science Signaling

Volumn 11, Issue 512, 2018, Pages

  Lee, Ji Hoon ^a   Mand, Michael R ^a   Kao, Chung Hsuan ^a   Zhou, Yi ^a   Ryu, Seung W ^a   Richards, Alicia L ^b,c   Coon, Joshua J ^b,c   Paull, Tanya T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASEIN KINASE II; DNA; DOUBLE STRAND BREAK REPAIR PROTEIN MRE11; MUTANT PROTEIN; NIBRIN; RAD50 PROTEIN; ATM PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; MRE11A PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD50 PROTEIN, HUMAN;

ALLELE; ARTICLE; AUTOPHAGY; CELL CYCLE CHECKPOINT; CELL FUNCTION; CELL METABOLISM; CELL SURVIVAL; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; SIGNAL TRANSDUCTION; BONE TUMOR; CELL NUCLEUS; GENETICS; METABOLISM; MUTATION; OSTEOSARCOMA; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL CULTURE;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; BONE NEOPLASMS; CELL CYCLE PROTEINS; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; HUMANS; MRE11 HOMOLOGUE PROTEIN; MUTATION; NUCLEAR PROTEINS; OSTEOSARCOMA; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEOSTASIS; TUMOR CELLS, CULTURED;

EID: 85040458140     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aan5598     Document Type: Article

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