Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms

Human Molecular Genetics

Volumn 22, Issue 25, 2013, Pages 5146-5159

  Regal, Joshua A ^a   Festerling, Todd A ^a   Buis, Jeffrey M ^a   Ferguson, David O ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; COMPLEMENTARY DNA; CRE RECOMBINASE; EXONUCLEASE; HISTONE H3; KAP1 PROTEIN; MESSENGER RNA; MRE11 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; ATAXIA TELANGIECTASIA; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CHILDHOOD CANCER; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; G2 PHASE CELL CYCLE CHECKPOINT; GENE MUTATION; HUMAN; LUNG ADENOCARCINOMA; M PHASE CELL CYCLE CHECKPOINT; NONSENSE MUTATION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

ALLELES; ATAXIA TELANGIECTASIA; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA-BINDING PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GENOMIC INSTABILITY; HUMANS; MUTATION; NEOPLASMS; SIGNAL TRANSDUCTION; SPINOCEREBELLAR DEGENERATIONS;

EID: 84888774584     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt368     Document Type: Article

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