-
1
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
Lavin MF, Shiloh Y. The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 1997; 15: 177-202.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
2
-
-
0034798285
-
ATM: Genome stability, neuronal development, and cancer cross paths
-
Shiloh Y, Kastan MB. ATM: genome stability, neuronal development, and cancer cross paths. Adv Cancer Res 2001; 83: 209-254.
-
(2001)
Adv. Cancer Res.
, vol.83
, pp. 209-254
-
-
Shiloh, Y.1
Kastan, M.B.2
-
3
-
-
0032514617
-
Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice
-
Eilam R, Peter Y, Elson A et al. Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice. Proc Natl Acad Sci USA 1998; 95: 12653-12656.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12653-12656
-
-
Eilam, R.1
Peter, Y.2
Elson, A.3
-
4
-
-
0037064053
-
ATM is activated in response to MNNG-induced DNA alkylation
-
Adamson AW, Kim WJ, Shangary S, Baskaran R, Brown KD. ATM is activated in response to MNNG-induced DNA alkylation. J Biol Chem 2002; 277: 38222-38229.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38222-38229
-
-
Adamson, A.W.1
Kim, W.J.2
Shangary, S.3
Baskaran, R.4
Brown, K.D.5
-
5
-
-
0035361407
-
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype
-
Spring K, Cross S, Li C et al. Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype. Cancer Res 2001; 61: 4561-4568.
-
(2001)
Cancer Res.
, vol.61
, pp. 4561-4568
-
-
Spring, K.1
Cross, S.2
Li, C.3
-
6
-
-
0032825373
-
ATM immunolocalization in mouse neuronal endosomes: Implications for ataxia-telangiectasia
-
Kuljis RO, Chen G, Lee EY, Aguila MC, Xu Y. ATM immunolocalization in mouse neuronal endosomes: implications for ataxia-telangiectasia. Brain Res 1999; 842: 351-358.
-
(1999)
Brain Res.
, vol.842
, pp. 351-358
-
-
Kuljis, R.O.1
Chen, G.2
Lee, E.Y.3
Aguila, M.C.4
Xu, Y.5
-
7
-
-
12944328742
-
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice
-
Borghesani PR, Alt FW, Bottaro A et al. Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proc Natl Acad Sci USA 2000; 97: 3336-3341.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3336-3341
-
-
Borghesani, P.R.1
Alt, F.W.2
Bottaro, A.3
-
8
-
-
0034700243
-
Mortality rates among carriers of ataxia-telangiectasia mutant alleles
-
Su Y, Swift M. Mortality rates among carriers of ataxia-telangiectasia mutant alleles. Ann Intern Med 2000; 133: 770-778.
-
(2000)
Ann. Intern. Med.
, vol.133
, pp. 770-778
-
-
Su, Y.1
Swift, M.2
-
9
-
-
0037162312
-
Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts
-
Worgul BV, Smilenov L, Brenner DJ, Junk A, Zhou W, Hall EJ. Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts. Proc Natl Acad Sci USA 2002; 99: 9836-9839.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9836-9839
-
-
Worgul, B.V.1
Smilenov, L.2
Brenner, D.J.3
Junk, A.4
Zhou, W.5
Hall, E.J.6
-
10
-
-
0035913159
-
Radiation induces genomic instability and mammary ductal dysplasia in Atm heterozygous mice
-
Weil MM, Kittrell FS, Yu Y, McCarthy M, Zabriskie RC, Ullrich RL. Radiation induces genomic instability and mammary ductal dysplasia in Atm heterozygous mice. Oncogene 2001; 20: 4409-4411.
-
(2001)
Oncogene
, vol.20
, pp. 4409-4411
-
-
Weil, M.M.1
Kittrell, F.S.2
Yu, Y.3
McCarthy, M.4
Zabriskie, R.C.5
Ullrich, R.L.6
-
11
-
-
0036727417
-
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
-
Spring K, Ahangari F, Scott SP et al. Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer. Nat Genet 2002; 32: 185-190.
-
(2002)
Nat. Genet.
, vol.32
, pp. 185-190
-
-
Spring, K.1
Ahangari, F.2
Scott, S.P.3
-
12
-
-
0031259793
-
Ataxia-telangiectasia: Is ATM a sensor of oxidative damage and stress?
-
Rotman G, Shiloh Y. Ataxia-telangiectasia: is ATM a sensor of oxidative damage and stress? Bioessays 1997; 19: 911-917.
-
(1997)
Bioessays
, vol.19
, pp. 911-917
-
-
Rotman, G.1
Shiloh, Y.2
-
13
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47-95.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 47-95
-
-
Droge, W.1
-
14
-
-
0034897532
-
How do neurons die in neurodegenerative diseases?
-
Kanazawa I. How do neurons die in neurodegenerative diseases? Trends Mol Med 2001; 7: 339-344.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 339-344
-
-
Kanazawa, I.1
-
15
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14: 927-939.
-
(2000)
Genes Dev.
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
16
-
-
0035202007
-
Chromosomal breakage syndromes and the BRCA1 genome surveillance complex
-
Futaki M, Liu JM. Chromosomal breakage syndromes and the BRCA1 genome surveillance complex. Trends Mol Med 2001; 7: 560-565.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 560-565
-
-
Futaki, M.1
Liu, J.M.2
-
17
-
-
18544372261
-
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM
-
Beamish H, Kedar P, Kaneko H et al. Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM. J Biol Chem 2002; 277: 30515-30523.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30515-30523
-
-
Beamish, H.1
Kedar, P.2
Kaneko, H.3
-
18
-
-
0037123768
-
Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways
-
Taniguchi T, Garcia-Higuera I, Xu B et al. Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways. Cell 2002; 109: 459-472.
-
(2002)
Cell
, vol.109
, pp. 459-472
-
-
Taniguchi, T.1
Garcia-Higuera, I.2
Xu, B.3
-
19
-
-
0036276388
-
The MRE11 complex: At the crossroads of DNA repair and checkpoint signalling
-
D'Amours D, Jackson SP. The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat Rev Mol Cell Biol 2002; 3: 317-327.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 317-327
-
-
D'Amours, D.1
Jackson, S.P.2
-
20
-
-
0035851090
-
Nuclear retention of ATM at sites of DNA double strand breaks
-
Andegeko Y, Moyal L, Mittelman L, Tsarfaty I, Shiloh Y, Rotman G. Nuclear retention of ATM at sites of DNA double strand breaks. J Biol Chem 2001; 276: 38224-38230.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38224-38230
-
-
Andegeko, Y.1
Moyal, L.2
Mittelman, L.3
Tsarfaty, I.4
Shiloh, Y.5
Rotman, G.6
-
21
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 2001; 276: 42462-42467.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
22
-
-
0036258350
-
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation
-
Foray N, Marot D, Randrianarison V et al. Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Mol Cell Biol 2002; 22: 4020-4032.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 4020-4032
-
-
Foray, N.1
Marot, D.2
Randrianarison, V.3
-
23
-
-
0033615547
-
Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase
-
Kim GD, Choi YH, Dimtchev A, Jeong SJ, Dritschilo A, Jung M. Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase. J Biol Chem 1999; 274: 31127-31130.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31127-31130
-
-
Kim, G.D.1
Choi, Y.H.2
Dimtchev, A.3
Jeong, S.J.4
Dritschilo, A.5
Jung, M.6
-
24
-
-
8244245266
-
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
-
Watters D, Khanna KK, Beamish H et al. Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene 1997; 14: 1911-1921.
-
(1997)
Oncogene
, vol.14
, pp. 1911-1921
-
-
Watters, D.1
Khanna, K.K.2
Beamish, H.3
-
25
-
-
0033607810
-
Localization of a portion of extranuclear ATM to peroxisomes
-
Watters D, Kedar P, Spring K et al. Localization of a portion of extranuclear ATM to peroxisomes. J Biol Chem 1999; 274: 34277-34282.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34277-34282
-
-
Watters, D.1
Kedar, P.2
Spring, K.3
-
27
-
-
0032555458
-
Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development
-
Oka A, Takashima S. Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development. Neurosci Lett 1998; 252: 195-198.
-
(1998)
Neurosci. Lett.
, vol.252
, pp. 195-198
-
-
Oka, A.1
Takashima, S.2
-
28
-
-
0029860045
-
Hypersensitivity of ataxia-telangiectasia fibroblasts to a nitric oxide donor
-
Green MH, Marcovitch AJ, Harcourt SA, Lowe JE, Green IC, Arlett CF. Hypersensitivity of ataxia-telangiectasia fibroblasts to a nitric oxide donor. Free Radic Biol Med 1997; 22: 343-347.
-
(1997)
Free Radic. Biol. Med.
, vol.22
, pp. 343-347
-
-
Green, M.H.1
Marcovitch, A.J.2
Harcourt, S.A.3
Lowe, J.E.4
Green, I.C.5
Arlett, C.F.6
-
29
-
-
0030985116
-
The ATM gene and protein: Possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress
-
Rotman G, Shiloh Y. The ATM gene and protein: possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress. Cancer Surv 1997; 29: 285-304.
-
(1997)
Cancer Surv.
, vol.29
, pp. 285-304
-
-
Rotman, G.1
Shiloh, Y.2
-
30
-
-
0034697333
-
Protective roles for ATM in cellular response to oxidative stress
-
Takao N, Li Y, Yamamoto K. Protective roles for ATM in cellular response to oxidative stress. FEBS Lett 2000; 472: 133-136.
-
(2000)
FEBS Lett.
, vol.472
, pp. 133-136
-
-
Takao, N.1
Li, Y.2
Yamamoto, K.3
-
31
-
-
0000437602
-
Anti-oxidative capacity in patients with ataxia telangiectasia
-
Reichenbach J, Schubert R, Schwan C, Muller K, Bohles HJ, Zielen S. Anti-oxidative capacity in patients with ataxia telangiectasia. Clin Exp Immunol 1999; 117: 535-539.
-
(1999)
Clin. Exp. Immunol.
, vol.117
, pp. 535-539
-
-
Reichenbach, J.1
Schubert, R.2
Schwan, C.3
Muller, K.4
Bohles, H.J.5
Zielen, S.6
-
32
-
-
0030590209
-
Ataxia telangiectasia heterozygotes and patients display increased fluidity and decrease in contents of sulfhydryl groups in red blood cell membranes
-
1302
-
Rybczynska M, Pawlak AL, Sikorska E, Ignatowicz R. Ataxia telangiectasia heterozygotes and patients display increased fluidity and decrease in contents of sulfhydryl groups in red blood cell membranes. Biochim Biophys Acta 1996; 1302: 231-235.
-
(1996)
Biochim. Biophys. Acta
, pp. 231-235
-
-
Rybczynska, M.1
Pawlak, A.L.2
Sikorska, E.3
Ignatowicz, R.4
-
33
-
-
0035905742
-
Ataxia-telangiectasia: Chronic activation of damage-responsive functions is reduced by alpha-lipoic acid
-
Gatei M, Shkedy D, Khanna KK et al. Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid. Oncogene 2001; 20: 289-294.
-
(2001)
Oncogene
, vol.20
, pp. 289-294
-
-
Gatei, M.1
Shkedy, D.2
Khanna, K.K.3
-
34
-
-
0032520894
-
Low catalase activity in xeroderma pigmentosum fibroblasts and SV40-transformed human cell lines is directly related to decreased intracellular levels of the cofactor, NADPH
-
Hoffschir F, Daya-Grosjean L, Petit PX et al. Low catalase activity in xeroderma pigmentosum fibroblasts and SV40-transformed human cell lines is directly related to decreased intracellular levels of the cofactor, NADPH. Free Radic Biol Med 1998; 24: 809-816.
-
(1998)
Free Radic. Biol. Med.
, vol.24
, pp. 809-816
-
-
Hoffschir, F.1
Daya-Grosjean, L.2
Petit, P.X.3
-
35
-
-
0033578411
-
Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs
-
Barlow C, Dennery PA, Shigenaga MK et al. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci USA 1999; 96: 9915-9919.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9915-9919
-
-
Barlow, C.1
Dennery, P.A.2
Shigenaga, M.K.3
-
36
-
-
0035011079
-
Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia
-
Quick KL, Dugan LL. Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia. Ann Neurol 2001; 49: 627-635.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 627-635
-
-
Quick, K.L.1
Dugan, L.L.2
-
37
-
-
0035266308
-
Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice
-
Kamsler A, Daily D, Hochman A et al. Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice. Cancer Res 2001; 61: 1849-1854.
-
(2001)
Cancer Res.
, vol.61
, pp. 1849-1854
-
-
Kamsler, A.1
Daily, D.2
Hochman, A.3
-
38
-
-
0035794540
-
Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice
-
Peter Y, Rotman G, Lotem J, Elson A, Shiloh Y, Groner Y. Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice. EMBO J 2001; 20: 1538-1546.
-
(2001)
EMBO J.
, vol.20
, pp. 1538-1546
-
-
Peter, Y.1
Rotman, G.2
Lotem, J.3
Elson, A.4
Shiloh, Y.5
Groner, Y.6
-
39
-
-
0035019463
-
The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes
-
Yan M, Qiang W, Liu N, Shen J, Lynn WS, Wong PK. The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes. FASEB J 2001; 15: 1132-1138.
-
(2001)
FASEB J.
, vol.15
, pp. 1132-1138
-
-
Yan, M.1
Qiang, W.2
Liu, N.3
Shen, J.4
Lynn, W.S.5
Wong, P.K.6
-
40
-
-
0035877581
-
The ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts
-
Shackelford RE, Innes CL, Sieber SO, Heinloth AN, Leadon SA, Paules RS. The ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts. J Biol Chem 2001; 276: 21951-21959.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21951-21959
-
-
Shackelford, R.E.1
Innes, C.L.2
Sieber, S.O.3
Heinloth, A.N.4
Leadon, S.A.5
Paules, R.S.6
-
41
-
-
0032497587
-
A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB
-
Lee SJ, Dimtchev A, Lavin MF, Dritschilo A, Jung M. A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB. Oncogene 1998; 17: 1821-1826.
-
(1998)
Oncogene
, vol.17
, pp. 1821-1826
-
-
Lee, S.J.1
Dimtchev, A.2
Lavin, M.F.3
Dritschilo, A.4
Jung, M.5
-
42
-
-
0035937809
-
ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks
-
Li N, Banin S, Ouyang H et al. ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks. J Biol Chem 2001; 276: 8898-8903.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8898-8903
-
-
Li, N.1
Banin, S.2
Ouyang, H.3
-
44
-
-
85047699658
-
ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage
-
Bar-Shira A, Rashi-Elkeles S, Zlochover L et al. ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage. Oncogene 2002; 21: 849-855.
-
(2002)
Oncogene
, vol.21
, pp. 849-855
-
-
Bar-Shira, A.1
Rashi-Elkeles, S.2
Zlochover, L.3
-
45
-
-
0033662152
-
An unlikely player joins the ATM signalling network
-
Lavin MF. An unlikely player joins the ATM signalling network. Nat Cell Biol 2000; 2: E215-E217.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Lavin, M.F.1
-
46
-
-
0035913160
-
Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein
-
Keating KE, Gueven N, Watters D, Rodemann HP, Lavin MF. Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein. Oncogene 2001; 20: 4281-4290.
-
(2001)
Oncogene
, vol.20
, pp. 4281-4290
-
-
Keating, K.E.1
Gueven, N.2
Watters, D.3
Rodemann, H.P.4
Lavin, M.F.5
-
47
-
-
0032697807
-
Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity
-
Gosink EC, Chong MJ, McKinnon PJ. Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity. Cancer Res 1999; 59: 5294-5298.
-
(1999)
Cancer Res.
, vol.59
, pp. 5294-5298
-
-
Gosink, E.C.1
Chong, M.J.2
McKinnon, P.J.3
-
48
-
-
0035281565
-
Ataxia telangiectasia mutated is essential during adult neurogenesis
-
Allen DM, van Praag H, Ray J et al. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev 2001; 15: 554-566.
-
(2001)
Genes Dev.
, vol.15
, pp. 554-566
-
-
Allen, D.M.1
van Praag, H.2
Ray, J.3
-
49
-
-
0033662156
-
Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1
-
Yang DQ, Kastan MB. Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. Nat Cell Biol 2000; 2: 893-898.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 893-898
-
-
Yang, D.Q.1
Kastan, M.B.2
-
50
-
-
0037008730
-
Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture
-
Zhang X, Shu L, Hosoi H, Murti KG, Houghton PJ. Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture. J Biol Chem 2002; 277: 28127-28134.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28127-28134
-
-
Zhang, X.1
Shu, L.2
Hosoi, H.3
Murti, K.G.4
Houghton, P.J.5
-
51
-
-
0035852706
-
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
-
Peretz S, Jensen R, Baserga R, Glazer PM. ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response. Proc Natl Acad Sci USA 2001; 98: 1676-1681.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1676-1681
-
-
Peretz, S.1
Jensen, R.2
Baserga, R.3
Glazer, P.M.4
-
52
-
-
0035811559
-
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
Macaulay VM, Salisbury AJ, Bohula EA, Playford MP, Smorodinsky NI, Shiloh Y. Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 2001; 20: 4029-4040.
-
(2001)
Oncogene
, vol.20
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
Playford, M.P.4
Smorodinsky, N.I.5
Shiloh, Y.6
-
53
-
-
0036038184
-
Insulin-like growth factor I receptor is expressed at normal levels in Nijmegen breakage syndrome cells
-
Watanabe H, Yu D, Sasaki T et al. Insulin-like growth factor I receptor is expressed at normal levels in Nijmegen breakage syndrome cells. Biochem Biophys Res Commun 2002; 296: 62-66.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 62-66
-
-
Watanabe, H.1
Yu, D.2
Sasaki, T.3
-
54
-
-
0027230816
-
Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia
-
Kondo N, Inoue R, Nishimura S et al. Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia. Scand J Immunol 1993; 38: 45-48.
-
(1993)
Scand. J. Immunol.
, vol.38
, pp. 45-48
-
-
Kondo, N.1
Inoue, R.2
Nishimura, S.3
-
56
-
-
0035068963
-
Novel mutations and defective protein kinase C activation of T-lymphocytes in ataxia telangiectasia
-
Garcia-Perez MA, Allende LM, Corell A et al. Novel mutations and defective protein kinase C activation of T-lymphocytes in ataxia telangiectasia. Clin Exp Immunol 2001; 123: 472-480.
-
(2001)
Clin. Exp. Immunol.
, vol.123
, pp. 472-480
-
-
Garcia-Perez, M.A.1
Allende, L.M.2
Corell, A.3
-
57
-
-
0035448927
-
Ataxia telangiectasia mutated-dependent apoptosis after genotoxic stress in the developing nervous system is determined by cellular differentiation status
-
Lee Y, Chong MJ, McKinnon PJ. Ataxia telangiectasia mutated-dependent apoptosis after genotoxic stress in the developing nervous system is determined by cellular differentiation status. J Neurosci 2001; 21: 6687-6693.
-
(2001)
J. Neurosci.
, vol.21
, pp. 6687-6693
-
-
Lee, Y.1
Chong, M.J.2
McKinnon, P.J.3
-
58
-
-
0037016764
-
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice
-
Stern N, Hochman A, Zemach N et al. Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. J Biol Chem 2002; 277: 602-608.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 602-608
-
-
Stern, N.1
Hochman, A.2
Zemach, N.3
-
59
-
-
0037098407
-
The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells
-
Marecki JC, McCord JM. The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells. Arch Biochem Biophys 2002; 402: 227-234.
-
(2002)
Arch. Biochem. Biophys.
, vol.402
, pp. 227-234
-
-
Marecki, J.C.1
McCord, J.M.2
-
60
-
-
0035879043
-
Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress
-
Meira LB, Devaraj S, Kisby GE et al. Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. Cancer Res 2001; 61: 5552-5557.
-
(2001)
Cancer Res.
, vol.61
, pp. 5552-5557
-
-
Meira, L.B.1
Devaraj, S.2
Kisby, G.E.3
-
61
-
-
0037086702
-
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
-
Kang J, Bronson RT, Xu Y. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J 2002; 21: 1447-1455.
-
(2002)
EMBO J.
, vol.21
, pp. 1447-1455
-
-
Kang, J.1
Bronson, R.T.2
Xu, Y.3
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