Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 1, 2008, Pages

  Sharma, Shruti ^a   Sud, Neetu ^a   Wiseman, Dean A ^a   Carter, A Lee ^a   Kumar, Sanjiv ^a   Hou, Yali ^a   Rau, Thomas ^b   Wilham, Jason ^b   Harmon, Cynthia ^c   Oishi, Peter ^c   Fineman, Jeffrey R ^c,d   Black, Stephen M ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF MONTANA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carnitine metabolism; Oxidative stress

Indexed keywords

ACYLCARNITINE; ADENOSINE TRIPHOSPHATE; CARNITINE; CARNITINE ACETYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 2; CARNITINE PALMITOYLTRANSFERASE I; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEAT SHOCK PROTEIN 90; LACTIC ACID; NITRIC OXIDE; PYRUVIC ACID; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; HOMEOSTASIS; LAMB; LUNG ARTERY; LUNG BLOOD FLOW; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PULMONARY HYPERTENSION;

ANIMALS; ANIMALS, NEWBORN; CARNITINE; CARNITINE O-ACETYLTRANSFERASE; CARNITINE O-PALMITOYLTRANSFERASE; DELIVERY, OBSTETRIC; DISEASE MODELS, ANIMAL; FEMALE; HOMEOSTASIS; HSP90 HEAT-SHOCK PROTEINS; HYPERTENSION, PULMONARY; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PREGNANCY; PULMONARY CIRCULATION; REGIONAL BLOOD FLOW; SHEEP; SIGNAL TRANSDUCTION;

EID: 40749112818     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00247.2007     Document Type: Article

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