-
1
-
-
0032539582
-
Kinetic and mechanistic studies on the hydrolysis of ubiquitin C- terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes
-
DOI 10.1021/bi9723360
-
L.C. Dang, F.D. Melandri, and R.L. Stein Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes Biochemistry 37 1998 1868 1879 (Pubitemid 28099809)
-
(1998)
Biochemistry
, vol.37
, Issue.7
, pp. 1868-1879
-
-
Dang, L.C.1
Melandri, F.D.2
Stein, R.L.3
-
3
-
-
77952576359
-
Negative regulation of Vps34 by Cdk mediated phosphorylation
-
T. Furuya, M. Kim, M. Lipinski, J. Li, D. Kim, T. Lu, Y. Shen, L. Rameh, B. Yankner, and L.H. Tsai Negative regulation of Vps34 by Cdk mediated phosphorylation Mol. Cell 38 2010 500 511
-
(2010)
Mol. Cell
, vol.38
, pp. 500-511
-
-
Furuya, T.1
Kim, M.2
Lipinski, M.3
Li, J.4
Kim, D.5
Lu, T.6
Shen, Y.7
Rameh, L.8
Yankner, B.9
Tsai, L.H.10
-
4
-
-
0032581670
-
FYVE fingers bind PtdIns(3)P
-
J.M. Gaullier, A. Simonsen, A. D'Arrigo, B. Bremnes, H. Stenmark, and R. Aasland FYVE fingers bind PtdIns(3)P Nature 394 1998 432 433
-
(1998)
Nature
, vol.394
, pp. 432-433
-
-
Gaullier, J.M.1
Simonsen, A.2
D'Arrigo, A.3
Bremnes, B.4
Stenmark, H.5
Aasland, R.6
-
5
-
-
0038784526
-
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
-
DOI 10.1016/S0092-8674(03)00480-X
-
O. Gozani, P. Karuman, D.R. Jones, D. Ivanov, J. Cha, A.A. Lugovskoy, C.L. Baird, H. Zhu, S.J. Field, and S.L. Lessnick The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor Cell 114 2003 99 111 (Pubitemid 36859844)
-
(2003)
Cell
, vol.114
, Issue.1
, pp. 99-111
-
-
Gozani, O.1
Karuman, P.2
Jones, D.R.3
Ivanov, D.4
Cha, J.5
Lugovskoy, A.A.6
Baird, C.L.7
Zhu, H.8
Field, S.J.9
Lessnick, S.L.10
Villasenor, J.11
Mehrotra, B.12
Chen, J.13
Rao, V.R.14
Brugge, J.S.15
Ferguson, C.G.16
Payrastre, B.17
Myszka, D.G.18
Cantley, L.C.19
Wagner, G.20
Divecha, N.21
Prestwich, G.D.22
Yuan, J.23
more..
-
6
-
-
27744516748
-
Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14
-
DOI 10.1038/sj.emboj.7600832, PII 7600832
-
M. Hu, P. Li, L. Song, P.D. Jeffrey, T.A. Chenova, K.D. Wilkinson, R.E. Cohen, and Y. Shi Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14 EMBO. J. 24 2005 3747 3756 (Pubitemid 41581691)
-
(2005)
EMBO Journal
, vol.24
, Issue.21
, pp. 3747-3756
-
-
Hu, M.1
Li, P.2
Song, L.3
Jeffrey, P.D.4
Chenova, T.A.5
Wilkinson, K.D.6
Cohen, R.E.7
Shi, Y.8
-
7
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
-
E. Itakura, C. Kishi, K. Inoue, and N. Mizushima Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG Mol. Biol. Cell 19 2008 5360 5372
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
8
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
T. Jacks, L. Remington, B.O. Williams, E.M. Schmitt, S. Halachmi, R.T. Bronson, and R.A. Weinberg Tumor spectrum analysis in p53-mutant mice Curr. Biol. 4 1994 1 7
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
Weinberg, R.A.7
-
9
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
DOI 10.1101/gad.1565707
-
V. Karantza-Wadsworth, S. Patel, O. Kravchuk, G. Chen, R. Mathew, S. Jin, and E. White Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis Genes Dev. 21 2007 1621 1635 (Pubitemid 47026367)
-
(2007)
Genes and Development
, vol.21
, Issue.13
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
Chen, G.4
Mathew, R.5
Jin, S.6
White, E.7
-
10
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
A.G. Knudson Jr. Mutation and cancer: statistical study of retinoblastoma Proc. Natl. Acad. Sci. USA 68 1971 820 823
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 820-823
-
-
Knudson, Jr.A.G.1
-
11
-
-
80052265841
-
Mechanism, specificity and structure of the deubiquitinases
-
D. Komander Mechanism, specificity and structure of the deubiquitinases Subcell Biochem. 54 2010 69 87
-
(2010)
Subcell Biochem.
, vol.54
, pp. 69-87
-
-
Komander, D.1
-
12
-
-
77956527159
-
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
-
B.H. Lee, M.J. Lee, S. Park, D.C. Oh, S. Elsasser, P.C. Chen, C. Gartner, N. Dimova, J. Hanna, and S.P. Gygi Enhancement of proteasome activity by a small-molecule inhibitor of USP14 Nature 467 2010 179 184
-
(2010)
Nature
, vol.467
, pp. 179-184
-
-
Lee, B.H.1
Lee, M.J.2
Park, S.3
Oh, D.C.4
Elsasser, S.5
Chen, P.C.6
Gartner, C.7
Dimova, N.8
Hanna, J.9
Gygi, S.P.10
-
13
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
C. Liang, P. Feng, B. Ku, I. Dotan, D. Canaani, B.H. Oh, and J.U. Jung Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG Nat. Cell Biol. 8 2006 688 699
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
Jung, J.U.7
-
14
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
X.H. Liang, S. Jackson, M. Seaman, K. Brown, B. Kempkes, H. Hibshoosh, and B. Levine Induction of autophagy and inhibition of tumorigenesis by beclin 1 Nature 402 1999 672 676 (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
15
-
-
33645078650
-
Regulation of membrane traffic by phosphoinositide 3-kinases
-
K. Lindmo, and H. Stenmark Regulation of membrane traffic by phosphoinositide 3-kinases J. Cell Sci. 119 2006 605 614
-
(2006)
J. Cell Sci.
, vol.119
, pp. 605-614
-
-
Lindmo, K.1
Stenmark, H.2
-
16
-
-
77954898129
-
A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions
-
M.M. Lipinski, G. Hoffman, A. Ng, W. Zhou, B.F. Py, E. Hsu, X. Liu, J. Eisenberg, J. Liu, and J. Blenis A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions Dev. Cell 18 2010 1041 1052
-
(2010)
Dev. Cell
, vol.18
, pp. 1041-1052
-
-
Lipinski, M.M.1
Hoffman, G.2
Ng, A.3
Zhou, W.4
Py, B.F.5
Hsu, E.6
Liu, X.7
Eisenberg, J.8
Liu, J.9
Blenis, J.10
-
17
-
-
33645127357
-
Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation
-
J.D. MacPherson, T.D. Gillespie, H.A. Dunkerley, D.H. Maurice, and B.M. Bennett Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation J. Pharmacol. Exp. Ther. 317 2006 188 195
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.317
, pp. 188-195
-
-
MacPherson, J.D.1
Gillespie, T.D.2
Dunkerley, H.A.3
Maurice, D.H.4
Bennett, B.M.5
-
18
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
K. Matsunaga, T. Saitoh, K. Tabata, H. Omori, T. Satoh, N. Kurotori, I. Maejima, K. Shirahama-Noda, T. Ichimura, and T. Isobe Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages Nat. Cell Biol. 11 2009 385 396
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
Maejima, I.7
Shirahama-Noda, K.8
Ichimura, T.9
Isobe, T.10
-
19
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
-
S. Pattingre, A. Tassa, X. Qu, R. Garuti, X.H. Liang, N. Mizushima, M. Packer, M.D. Schneider, and B. Levine Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy Cell 122 2005 927 939 (Pubitemid 41345209)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Xiao, H.L.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
20
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
DOI 10.1172/JCI200320039
-
X. Qu, J. Yu, G. Bhagat, N. Furuya, H. Hibshoosh, A. Troxel, J. Rosen, E.L. Eskelinen, N. Mizushima, and Y. Ohsumi Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene J. Clin. Invest. 112 2003 1809 1820 (Pubitemid 38063704)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.-L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
21
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
P.V. Schu, K. Takegawa, M.J. Fry, J.H. Stack, M.D. Waterfield, and S.D. Emr Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting Science 260 1993 88 91 (Pubitemid 23122750)
-
(1993)
Science
, vol.259
, Issue.5104
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
22
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptopic programmed cell death dependent on autophagy genes
-
DOI 10.1038/ncb1192
-
S. Shimizu, T. Kanaseki, N. Mizushima, T. Mizuta, S. Arakawa-Kobayashi, C.B. Thompson, and Y. Tsujimoto Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes Nat. Cell Biol. 6 2004 1221 1228 (Pubitemid 39625121)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.12
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
23
-
-
70349919804
-
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
-
A. Simonsen, and S.A. Tooze Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes J. Cell Biol. 186 2009 773 782
-
(2009)
J. Cell Biol.
, vol.186
, pp. 773-782
-
-
Simonsen, A.1
Tooze, S.A.2
-
24
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
A. Takamura, M. Komatsu, T. Hara, A. Sakamoto, C. Kishi, S. Waguri, Y. Eishi, O. Hino, K. Tanaka, and N. Mizushima Autophagy-deficient mice develop multiple liver tumors Genes Dev. 25 2011 795 800
-
(2011)
Genes Dev.
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
Eishi, Y.7
Hino, O.8
Tanaka, K.9
Mizushima, N.10
-
25
-
-
57049103481
-
Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity
-
H. Wang, Z. Yan, S. Yang, J. Cai, H. Robinson, and H. Ke Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry 47 2008 12760 12768
-
(2008)
Biochemistry
, vol.47
, pp. 12760-12768
-
-
Wang, H.1
Yan, Z.2
Yang, S.3
Cai, J.4
Robinson, H.5
Ke, H.6
-
26
-
-
75749132016
-
USP10 regulates p53 localization and stability by deubiquitinating p53
-
J. Yuan, K. Luo, L. Zhang, J.C. Cheville, and Z. Lou USP10 regulates p53 localization and stability by deubiquitinating p53 Cell 140 2010 384 396
-
(2010)
Cell
, vol.140
, pp. 384-396
-
-
Yuan, J.1
Luo, K.2
Zhang, L.3
Cheville, J.C.4
Lou, Z.5
-
27
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
DOI 10.1073/pnas.2436255100
-
Z. Yue, S. Jin, C. Yang, A.J. Levine, and N. Heintz Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor Proc. Natl. Acad. Sci. USA 100 2003 15077 15082 (Pubitemid 37518019)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
28
-
-
37649024076
-
Small molecule regulators of autophagy identified by an image-based high-throughput screen
-
L. Zhang, J. Yu, H. Pan, P. Hu, Y. Hao, W. Cai, H. Zhu, A.D. Yu, X. Xie, and D. Ma Small molecule regulators of autophagy identified by an image-based high-throughput screen Proc. Natl. Acad. Sci. USA 104 2007 19023 19028
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19023-19028
-
-
Zhang, L.1
Yu, J.2
Pan, H.3
Hu, P.4
Hao, Y.5
Cai, W.6
Zhu, H.7
Yu, A.D.8
Xie, X.9
Ma, D.10
-
29
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Y. Zhong, Q.J. Wang, X. Li, Y. Yan, J.M. Backer, B.T. Chait, N. Heintz, and Z. Yue Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex Nat. Cell Biol. 11 2009 468 476
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
-
30
-
-
0037161475
-
Protein lipid overlay assay
-
Dowler, S., Kular, G., and Alessi, D.R. (2002). Protein lipid overlay assay. Sci. STKE 2002, pl6.
-
(2002)
Sci. STKE
, vol.2002
-
-
Dowler, S.1
Kular, G.2
Alessi, D.R.3
-
31
-
-
0038784526
-
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
-
DOI 10.1016/S0092-8674(03)00480-X
-
Gozani, O., Karuman, P., Jones, D.R., Ivanov, D., Cha, J., Lugovskoy, A.A., Baird, C.L., Zhu, H., Field, S.J., Lessnick, S.L., et al. (2003). The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell 114, 99-111. (Pubitemid 36859844)
-
(2003)
Cell
, vol.114
, Issue.1
, pp. 99-111
-
-
Gozani, O.1
Karuman, P.2
Jones, D.R.3
Ivanov, D.4
Cha, J.5
Lugovskoy, A.A.6
Baird, C.L.7
Zhu, H.8
Field, S.J.9
Lessnick, S.L.10
Villasenor, J.11
Mehrotra, B.12
Chen, J.13
Rao, V.R.14
Brugge, J.S.15
Ferguson, C.G.16
Payrastre, B.17
Myszka, D.G.18
Cantley, L.C.19
Wagner, G.20
Divecha, N.21
Prestwich, G.D.22
Yuan, J.23
more..
-
32
-
-
75749132016
-
USP10 regulates p53 localization and stability by deubiquitinating p53
-
Yuan, J., Luo, K., Zhang, L., Cheville, J.C., and Lou, Z. (2010). USP10 regulates p53 localization and stability by deubiquitinating p53. Cell 140, 384-396.
-
(2010)
Cell
, vol.140
, pp. 384-396
-
-
Yuan, J.1
Luo, K.2
Zhang, L.3
Cheville, J.C.4
Lou, Z.5
-
33
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
DOI 10.1177/108705719900400206
-
Zhang, J.H., Chung, T.D., and Oldenburg, K.R. (1999). A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J. Biomol. Screen. 4, 67-73. (Pubitemid 29278954)
-
(1999)
Journal of Biomolecular Screening
, vol.4
, Issue.2
, pp. 67-73
-
-
Zhang, J.-H.1
Chung, T.D.Y.2
Oldenburg, K.R.3
|