Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans

Archives of Toxicology

Volumn 88, Issue 2, 2014, Pages 391-401

  McGill, Mitchell R ^a   Li, Feng ^a   Sharpe, Matthew R ^b   Williams, C David ^a   Curry, Steven C ^c,d   Ma, Xiaochao ^a   Jaeschke, Hartmut ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS HOSPITAL   (United States)

^c BANNER GOOD SAMARITAN MEDICAL CENTER   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Acetaminophen toxicity; Acylcarnitines; Biomarkers; Mitochondria

Indexed keywords

ACETAMINOPHEN; ACETYLCYSTEINE; ANIMALS; ANTIDOTES; BIOLOGICAL MARKERS; CARNITINE; DRUG OVERDOSE; DRUG-INDUCED LIVER INJURY; HUMANS; MALE; METABOLOMICS; MICE; MICE, INBRED C57BL; MITOCHONDRIA;

EID: 84893899581     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1118-1     Document Type: Article

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