The autophagy-senescence connection in chemotherapy: Must tumor cells (self) eat before they sleep

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 3, 2012, Pages 763-778

  Goehe, Rachel W ^a,b   Di, Xu ^c   Sharma, Khushboo ^a   Bristol, Molly L ^a   Henderson, Scott C ^a   Valerie, Kristoffer ^b   Rodier, Francis ^d,e   Davalos, Albert R ^f   Gewirtz, David A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; ATM PROTEIN; AUTOPHAGY PROTEIN 5; CAMPTOTHECIN; CHLOROQUINE; DOXORUBICIN; GLUTATHIONE; PROTEIN P21; PROTEIN P53; PROTEIN P62; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; SHORT HAIRPIN RNA;

ARTICLE; ATG5 GENE; ATG7 GENE; AUTOPHAGY; BREAST CANCER; CANCER CHEMOTHERAPY; CELL AGING; CELL STRAIN HCT116; CELL STRAIN MCF 7; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG RESPONSE; GENE; GENE SILENCING; INTRACELLULAR SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CAMPTOTHECIN; CELL AGING; CELL CULTURE TECHNIQUES; DNA DAMAGE; DOXORUBICIN; FLOW CYTOMETRY; HCT116 CELLS; HUMANS; MCF-7 CELLS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; REACTIVE OXYGEN SPECIES;

EID: 84869214214     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.197590     Document Type: Article

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