-
1
-
-
85021773073
-
The association between total phthalate concentration and non-communicable diseases and chronic inflammation in South Australian urban dwelling men
-
Bai, P.Y., Wittert, G., Taylor, A.W., Martin, S.A., Milne, R.W., Jenkins, A.J., Januszewski, A.S., Shi, Z., The association between total phthalate concentration and non-communicable diseases and chronic inflammation in South Australian urban dwelling men. Environ. Res. 158 (2017), 366–372.
-
(2017)
Environ. Res.
, vol.158
, pp. 366-372
-
-
Bai, P.Y.1
Wittert, G.2
Taylor, A.W.3
Martin, S.A.4
Milne, R.W.5
Jenkins, A.J.6
Januszewski, A.S.7
Shi, Z.8
-
2
-
-
84958093401
-
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan
-
Baker, D.J., Childs, B.G., Durik, M., Wijers, M.E., Sieben, C.J., Zhong, J., Saltness, R.A., Jeganathan, K.B., Verzosa, G.C., Pezeshki, A. et al., Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature 530 (2016), 184–189.
-
(2016)
Nature
, vol.530
, pp. 184-189
-
-
Baker, D.J.1
Childs, B.G.2
Durik, M.3
Wijers, M.E.4
Sieben, C.J.5
Zhong, J.6
Saltness, R.A.7
Jeganathan, K.B.8
Verzosa, G.C.9
Pezeshki, A.10
-
3
-
-
77957759265
-
Genetic studies reveal the role of the endocrine and metabolic systems in aging
-
Barzilai, N., Gabriely, I., Atzmon, G., Suh, Y., Rothenberg, D., Bergman, A., Genetic studies reveal the role of the endocrine and metabolic systems in aging. J. Clin. Endocrinol. Metab. 95 (2010), 4493–4500.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, pp. 4493-4500
-
-
Barzilai, N.1
Gabriely, I.2
Atzmon, G.3
Suh, Y.4
Rothenberg, D.5
Bergman, A.6
-
4
-
-
84861885929
-
The critical role of metabolic pathways in aging
-
Barzilai, N., Huffman, D.M., Muzumdar, R.H., Bartke, A., The critical role of metabolic pathways in aging. Diabetes 61 (2012), 1315–1322.
-
(2012)
Diabetes
, vol.61
, pp. 1315-1322
-
-
Barzilai, N.1
Huffman, D.M.2
Muzumdar, R.H.3
Bartke, A.4
-
5
-
-
84874986522
-
Age-associated alterations in inducible gene transcription in human CD4 + T lymphocytes
-
Bektas, A., Zhang, Y., Wood, W.H. 3rd, Becker, K.G., Madara, K., Ferrucci, L., Sen, R., Age-associated alterations in inducible gene transcription in human CD4 + T lymphocytes. Aging 5 (2013), 18–36.
-
(2013)
Aging
, vol.5
, pp. 18-36
-
-
Bektas, A.1
Zhang, Y.2
Wood, W.H.3
Becker, K.G.4
Madara, K.5
Ferrucci, L.6
Sen, R.7
-
6
-
-
85018350134
-
Does a bit of alcohol turn off inflammation and improve health?
-
Bektas, A., Sen, R., Ferrucci, L., Does a bit of alcohol turn off inflammation and improve health?. Age Ageing 45 (2016), 747–748.
-
(2016)
Age Ageing
, vol.45
, pp. 747-748
-
-
Bektas, A.1
Sen, R.2
Ferrucci, L.3
-
7
-
-
85030718149
-
Human T cell immunosenescence and inflammation in aging
-
Bektas, A., Schurman, S.H., Sen, R., Ferrucci, L., Human T cell immunosenescence and inflammation in aging. J. Leukoc. Biol. 102 (2017), 977–988.
-
(2017)
J. Leukoc. Biol.
, vol.102
, pp. 977-988
-
-
Bektas, A.1
Schurman, S.H.2
Sen, R.3
Ferrucci, L.4
-
8
-
-
84857055272
-
Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort
-
Bind, M.A., Baccarelli, A., Zanobetti, A., Tarantini, L., Suh, H., Vokonas, P., Schwartz, J., Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort. Epidemiology 23 (2012), 332–340.
-
(2012)
Epidemiology
, vol.23
, pp. 332-340
-
-
Bind, M.A.1
Baccarelli, A.2
Zanobetti, A.3
Tarantini, L.4
Suh, H.5
Vokonas, P.6
Schwartz, J.7
-
9
-
-
33749534161
-
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
-
Blackburn, E.H., Greider, C.W., Szostak, J.W., Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat. Med. 12 (2006), 1133–1138.
-
(2006)
Nat. Med.
, vol.12
, pp. 1133-1138
-
-
Blackburn, E.H.1
Greider, C.W.2
Szostak, J.W.3
-
10
-
-
84875738351
-
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
-
Cabreiro, F., Au, C., Leung, K.Y., Vergara-Irigaray, N., Cocheme, H.M., Noori, T., Weinkove, D., Schuster, E., Greene, N.D., Gems, D., Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism. Cell 153 (2013), 228–239.
-
(2013)
Cell
, vol.153
, pp. 228-239
-
-
Cabreiro, F.1
Au, C.2
Leung, K.Y.3
Vergara-Irigaray, N.4
Cocheme, H.M.5
Noori, T.6
Weinkove, D.7
Schuster, E.8
Greene, N.D.9
Gems, D.10
-
11
-
-
0035845283
-
In-vivo measurement of activated microglia in dementia
-
Cagnin, A., Brooks, D.J., Kennedy, A.M., Gunn, R.N., Myers, R., Turkheimer, F.E., Jones, T., Banati, R.B., In-vivo measurement of activated microglia in dementia. Lancet 358 (2001), 461–467.
-
(2001)
Lancet
, vol.358
, pp. 461-467
-
-
Cagnin, A.1
Brooks, D.J.2
Kennedy, A.M.3
Gunn, R.N.4
Myers, R.5
Turkheimer, F.E.6
Jones, T.7
Banati, R.B.8
-
12
-
-
85020136063
-
Brain metabolism in health, aging, and neurodegeneration
-
Camandola, S., Mattson, M.P., Brain metabolism in health, aging, and neurodegeneration. EMBO J. 36 (2017), 1474–1492.
-
(2017)
EMBO J.
, vol.36
, pp. 1474-1492
-
-
Camandola, S.1
Mattson, M.P.2
-
13
-
-
0033846236
-
Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance?
-
Casey, A., Greenhaff, P.L., Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance?. Am. J. Clin. Nutr. 72 (2000), 607S–617S.
-
(2000)
Am. J. Clin. Nutr.
, vol.72
, pp. 607S-617S
-
-
Casey, A.1
Greenhaff, P.L.2
-
14
-
-
85015054307
-
Nature, nurture and human disease
-
Chakravarti, A., Little, P., Nature, nurture and human disease. Nature 421 (2003), 412–414.
-
(2003)
Nature
, vol.421
, pp. 412-414
-
-
Chakravarti, A.1
Little, P.2
-
15
-
-
84879391795
-
SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
-
Chang, H.C., Guarente, L., SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging. Cell 153 (2013), 1448–1460.
-
(2013)
Cell
, vol.153
, pp. 1448-1460
-
-
Chang, H.C.1
Guarente, L.2
-
16
-
-
84949555897
-
Cellular senescence in aging and age-related disease: from mechanisms to therapy
-
Childs, B.G., Durik, M., Baker, D.J., van Deursen, J.M., Cellular senescence in aging and age-related disease: from mechanisms to therapy. Nat. Med. 21 (2015), 1424–1435.
-
(2015)
Nat. Med.
, vol.21
, pp. 1424-1435
-
-
Childs, B.G.1
Durik, M.2
Baker, D.J.3
van Deursen, J.M.4
-
17
-
-
85030756466
-
Senescent cells: an emerging target for diseases of ageing
-
Childs, B.G., Gluscevic, M., Baker, D.J., Laberge, R.M., Marquess, D., Dananberg, J., van Deursen, J.M., Senescent cells: an emerging target for diseases of ageing. Nat. Rev. Drug Discov. 16 (2017), 718–735.
-
(2017)
Nat. Rev. Drug Discov.
, vol.16
, pp. 718-735
-
-
Childs, B.G.1
Gluscevic, M.2
Baker, D.J.3
Laberge, R.M.4
Marquess, D.5
Dananberg, J.6
van Deursen, J.M.7
-
18
-
-
0033792614
-
Fibroblast cultures from healthy centenarians have an active proteasome
-
Chondrogianni, N., Petropoulos, I., Franceschi, C., Friguet, B., Gonos, E.S., Fibroblast cultures from healthy centenarians have an active proteasome. Exp. Gerontol. 35 (2000), 721–728.
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 721-728
-
-
Chondrogianni, N.1
Petropoulos, I.2
Franceschi, C.3
Friguet, B.4
Gonos, E.S.5
-
19
-
-
85044110877
-
Functional insights into the creatine transporter
-
G.S. Salomons M. Wyss Springer Netherlands Dordrecht
-
Christie, D.L., Functional insights into the creatine transporter. Salomons, G.S., Wyss, M., (eds.) Creatine and Creatine Kinase in Health and Disease, 2007, Springer Netherlands, Dordrecht.
-
(2007)
Creatine and Creatine Kinase in Health and Disease
-
-
Christie, D.L.1
-
20
-
-
84902603273
-
Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2
-
De Haes, W., Frooninckx, L., Van Assche, R., Smolders, A., Depuydt, G., Billen, J., Braeckman, B.P., Schoofs, L., Temmerman, L., Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), E2501–2509.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. E2501-2509
-
-
De Haes, W.1
Frooninckx, L.2
Van Assche, R.3
Smolders, A.4
Depuydt, G.5
Billen, J.6
Braeckman, B.P.7
Schoofs, L.8
Temmerman, L.9
-
21
-
-
84881371312
-
The clinical maze of mitochondrial neurology
-
DiMauro, S., Schon, E.A., Carelli, V., Hirano, M., The clinical maze of mitochondrial neurology. Nat. Rev. Neurol. 9 (2013), 429–444.
-
(2013)
Nat. Rev. Neurol.
, vol.9
, pp. 429-444
-
-
DiMauro, S.1
Schon, E.A.2
Carelli, V.3
Hirano, M.4
-
22
-
-
44049096663
-
Tightly coupled brain activity and cerebral ATP metabolic rate
-
Du, F., Zhu, X.H., Zhang, Y., Friedman, M., Zhang, N., Ugurbil, K., Chen, W., Tightly coupled brain activity and cerebral ATP metabolic rate. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 6409–6414.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6409-6414
-
-
Du, F.1
Zhu, X.H.2
Zhang, Y.3
Friedman, M.4
Zhang, N.5
Ugurbil, K.6
Chen, W.7
-
23
-
-
84922789990
-
Nutrient-sensing mechanisms and pathways
-
Efeyan, A., Comb, W.C., Sabatini, D.M., Nutrient-sensing mechanisms and pathways. Nature 517 (2015), 302–310.
-
(2015)
Nature
, vol.517
, pp. 302-310
-
-
Efeyan, A.1
Comb, W.C.2
Sabatini, D.M.3
-
24
-
-
84922470859
-
Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers
-
Fabbri, E., An, Y., Zoli, M., Simonsick, E.M., Guralnik, J.M., Bandinelli, S., Boyd, C.M., Ferrucci, L., Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. J. Gerontol. A Biol. Sci. Med. Sci. 70 (2015), 63–70.
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.70
, pp. 63-70
-
-
Fabbri, E.1
An, Y.2
Zoli, M.3
Simonsick, E.M.4
Guralnik, J.M.5
Bandinelli, S.6
Boyd, C.M.7
Ferrucci, L.8
-
25
-
-
85013194968
-
Early body composition, but not body mass, is associated with future accelerated decline in muscle quality
-
Fabbri, E., Chiles Shaffer, N., Gonzalez-Freire, M., Shardell, M.D., Zoli, M., Studenski, S.A., Ferrucci, L., Early body composition, but not body mass, is associated with future accelerated decline in muscle quality. J. Cachexia. Sarcopenia Muscle 8 (2017), 490–499.
-
(2017)
J. Cachexia. Sarcopenia Muscle
, vol.8
, pp. 490-499
-
-
Fabbri, E.1
Chiles Shaffer, N.2
Gonzalez-Freire, M.3
Shardell, M.D.4
Zoli, M.5
Studenski, S.A.6
Ferrucci, L.7
-
26
-
-
85007448569
-
Cardiac oxidative stress in diabetes: mechanisms and therapeutic potential
-
Faria, A., Persaud, S.J., Cardiac oxidative stress in diabetes: mechanisms and therapeutic potential. Pharmacol. Ther. 172 (2017), 50–62.
-
(2017)
Pharmacol. Ther.
, vol.172
, pp. 50-62
-
-
Faria, A.1
Persaud, S.J.2
-
27
-
-
84866558633
-
Chapter 72. Clinical problems of aging
-
D.L. Longo A.S. Fauci D.L. Kasper S.L. Hauser J.L. Jameson J. Loscalzo The McGraw-Hill Companies New York, NY
-
Ferrucci, L., Studenski, S., Chapter 72. Clinical problems of aging. Longo, D.L., Fauci, A.S., Kasper, D.L., Hauser, S.L., Jameson, J.L., Loscalzo, J., (eds.) Harrison's Principles of Internal Medicine, 18e, 2012, The McGraw-Hill Companies, New York, NY.
-
(2012)
Harrison's Principles of Internal Medicine
, vol.18e
-
-
Ferrucci, L.1
Studenski, S.2
-
28
-
-
0033024330
-
Serum IL-6 level and the development of disability in older persons
-
Ferrucci, L., Harris, T.B., Guralnik, J.M., Tracy, R.P., Corti, M.C., Cohen, H.J., Penninx, B., Pahor, M., Wallace, R., Havlik, R.J., Serum IL-6 level and the development of disability in older persons. J. Am. Geriatr. Soc. 47 (1999), 639–646.
-
(1999)
J. Am. Geriatr. Soc.
, vol.47
, pp. 639-646
-
-
Ferrucci, L.1
Harris, T.B.2
Guralnik, J.M.3
Tracy, R.P.4
Corti, M.C.5
Cohen, H.J.6
Penninx, B.7
Pahor, M.8
Wallace, R.9
Havlik, R.J.10
-
29
-
-
0036903170
-
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels
-
Ferrucci, L., Penninx, B.W., Volpato, S., Harris, T.B., Bandeen-Roche, K., Balfour, J., Leveille, S.G., Fried, L.P., Md, J.M., Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J. Am. Geriatr. Soc. 50 (2002), 1947–1954.
-
(2002)
J. Am. Geriatr. Soc.
, vol.50
, pp. 1947-1954
-
-
Ferrucci, L.1
Penninx, B.W.2
Volpato, S.3
Harris, T.B.4
Bandeen-Roche, K.5
Balfour, J.6
Leveille, S.G.7
Fried, L.P.8
Md, J.M.9
-
30
-
-
15244348518
-
The origins of age-related proinflammatory state
-
Ferrucci, L., Corsi, A., Lauretani, F., Bandinelli, S., Bartali, B., Taub, D.D., Guralnik, J.M., Longo, D.L., The origins of age-related proinflammatory state. Blood 105 (2005), 2294–2299.
-
(2005)
Blood
, vol.105
, pp. 2294-2299
-
-
Ferrucci, L.1
Corsi, A.2
Lauretani, F.3
Bandinelli, S.4
Bartali, B.5
Taub, D.D.6
Guralnik, J.M.7
Longo, D.L.8
-
31
-
-
79959718815
-
Frailty as a nexus between the biology of aging, environmental conditions and clinical geriatrics
-
Ferrucci, L., Hesdorffer, C., Bandinelli, S., Simonsick, E.M., Frailty as a nexus between the biology of aging, environmental conditions and clinical geriatrics. Public Health Rev. 32 (2010), 475–488.
-
(2010)
Public Health Rev.
, vol.32
, pp. 475-488
-
-
Ferrucci, L.1
Hesdorffer, C.2
Bandinelli, S.3
Simonsick, E.M.4
-
32
-
-
84903710272
-
Interaction between bone and muscle in older persons with mobility limitations
-
Ferrucci, L., Baroni, M., Ranchelli, A., Lauretani, F., Maggio, M., Mecocci, P., Ruggiero, C., Interaction between bone and muscle in older persons with mobility limitations. Curr. Pharm. Des. 20 (2014), 3178–3197.
-
(2014)
Curr. Pharm. Des.
, vol.20
, pp. 3178-3197
-
-
Ferrucci, L.1
Baroni, M.2
Ranchelli, A.3
Lauretani, F.4
Maggio, M.5
Mecocci, P.6
Ruggiero, C.7
-
33
-
-
23244441435
-
Accelerated longitudinal decline of aerobic capacity in healthy older adults
-
Fleg, J.L., Morrell, C.H., Bos, A.G., Brant, L.J., Talbot, L.A., Wright, J.G., Lakatta, E.G., Accelerated longitudinal decline of aerobic capacity in healthy older adults. Circulation 112 (2005), 674–682.
-
(2005)
Circulation
, vol.112
, pp. 674-682
-
-
Fleg, J.L.1
Morrell, C.H.2
Bos, A.G.3
Brant, L.J.4
Talbot, L.A.5
Wright, J.G.6
Lakatta, E.G.7
-
34
-
-
0027464362
-
Body fat distribution and 5-year risk of death in older women
-
Folsom, A.R., Kaye, S.A., Sellers, T.A., Hong, C.P., Cerhan, J.R., Potter, J.D., Prineas, R.J., Body fat distribution and 5-year risk of death in older women. JAMA 269 (1993), 483–487.
-
(1993)
JAMA
, vol.269
, pp. 483-487
-
-
Folsom, A.R.1
Kaye, S.A.2
Sellers, T.A.3
Hong, C.P.4
Cerhan, J.R.5
Potter, J.D.6
Prineas, R.J.7
-
35
-
-
84955178200
-
Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial
-
Fontana, L., Villareal, D.T., Das, S.K., Smith, S.R., Meydani, S.N., Pittas, A.G., Klein, S., Bhapkar, M., Rochon, J., Ravussin, E. et al., Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial. Aging Cell 15 (2016), 22–27.
-
(2016)
Aging Cell
, vol.15
, pp. 22-27
-
-
Fontana, L.1
Villareal, D.T.2
Das, S.K.3
Smith, S.R.4
Meydani, S.N.5
Pittas, A.G.6
Klein, S.7
Bhapkar, M.8
Rochon, J.9
Ravussin, E.10
-
36
-
-
84949772416
-
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
-
Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H.K. et al., Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 528 (2015), 262–266.
-
(2015)
Nature
, vol.528
, pp. 262-266
-
-
Forslund, K.1
Hildebrand, F.2
Nielsen, T.3
Falony, G.4
Le Chatelier, E.5
Sunagawa, S.6
Prifti, E.7
Vieira-Silva, S.8
Gudmundsdottir, V.9
Pedersen, H.K.10
-
37
-
-
84900988267
-
Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
-
Franceschi, C., Campisi, J., Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J. Gerontol. A Biol. Sci. Med. Sci. 69:Suppl. 1 (2014), S4–9.
-
(2014)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.69
, pp. S4-9
-
-
Franceschi, C.1
Campisi, J.2
-
38
-
-
33846111415
-
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans
-
Franceschi, C., Capri, M., Monti, D., Giunta, S., Olivieri, F., Sevini, F., Panourgia, M.P., Invidia, L., Celani, L., Scurti, M. et al., Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech. Ageing Dev. 128 (2007), 92–105.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 92-105
-
-
Franceschi, C.1
Capri, M.2
Monti, D.3
Giunta, S.4
Olivieri, F.5
Sevini, F.6
Panourgia, M.P.7
Invidia, L.8
Celani, L.9
Scurti, M.10
-
39
-
-
85005959021
-
Inflammaging and ‘Garb-aging’
-
Franceschi, C., Garagnani, P., Vitale, G., Capri, M., Salvioli, S., Inflammaging and ‘Garb-aging’. Trends Endocrinol. Metab. 28 (2017), 199–212.
-
(2017)
Trends Endocrinol. Metab.
, vol.28
, pp. 199-212
-
-
Franceschi, C.1
Garagnani, P.2
Vitale, G.3
Capri, M.4
Salvioli, S.5
-
40
-
-
84954391956
-
The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?
-
Fuku, N., Pareja-Galeano, H., Zempo, H., Alis, R., Arai, Y., Lucia, A., Hirose, N., The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?. Aging Cell 14 (2015), 921–923.
-
(2015)
Aging Cell
, vol.14
, pp. 921-923
-
-
Fuku, N.1
Pareja-Galeano, H.2
Zempo, H.3
Alis, R.4
Arai, Y.5
Lucia, A.6
Hirose, N.7
-
41
-
-
84942905127
-
Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5 y
-
Garcia-Calzon, S., Zalba, G., Ruiz-Canela, M., Shivappa, N., Hebert, J.R., Martinez, J.A., Fito, M., Gomez-Gracia, E., Martinez-Gonzalez, M.A., Marti, A., Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5 y. Am. J. Clin. Nutr. 102 (2015), 897–904.
-
(2015)
Am. J. Clin. Nutr.
, vol.102
, pp. 897-904
-
-
Garcia-Calzon, S.1
Zalba, G.2
Ruiz-Canela, M.3
Shivappa, N.4
Hebert, J.R.5
Martinez, J.A.6
Fito, M.7
Gomez-Gracia, E.8
Martinez-Gonzalez, M.A.9
Marti, A.10
-
42
-
-
4544366928
-
Living with the past: evolution, development, and patterns of disease
-
Gluckman, P.D., Hanson, M.A., Living with the past: evolution, development, and patterns of disease. Science 305 (2004), 1733–1736.
-
(2004)
Science
, vol.305
, pp. 1733-1736
-
-
Gluckman, P.D.1
Hanson, M.A.2
-
43
-
-
84927748959
-
Drivers of age-related inflammation and strategies for healthspan extension
-
Goldberg, E.L., Dixit, V.D., Drivers of age-related inflammation and strategies for healthspan extension. Immunol. Rev. 265 (2015), 63–74.
-
(2015)
Immunol. Rev.
, vol.265
, pp. 63-74
-
-
Goldberg, E.L.1
Dixit, V.D.2
-
44
-
-
0035097033
-
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
-
Harman, S.M., Metter, E.J., Tobin, J.D., Pearson, J., Blackman, M.R., Baltimore Longitudinal Study of, A., Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J. Clin. Endocrinol. Metab. 86 (2001), 724–731.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 724-731
-
-
Harman, S.M.1
Metter, E.J.2
Tobin, J.D.3
Pearson, J.4
Blackman, M.R.5
Baltimore Longitudinal Study of, A.6
-
45
-
-
77956410464
-
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation
-
Hawley, S.A., Ross, F.A., Chevtzoff, C., Green, K.A., Evans, A., Fogarty, S., Towler, M.C., Brown, L.J., Ogunbayo, O.A., Evans, A.M. et al., Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation. Cell Metab. 11 (2010), 554–565.
-
(2010)
Cell Metab.
, vol.11
, pp. 554-565
-
-
Hawley, S.A.1
Ross, F.A.2
Chevtzoff, C.3
Green, K.A.4
Evans, A.5
Fogarty, S.6
Towler, M.C.7
Brown, L.J.8
Ogunbayo, O.A.9
Evans, A.M.10
-
46
-
-
85020028464
-
Senescence in health and disease
-
He, S., Sharpless, N.E., Senescence in health and disease. Cell 169 (2017), 1000–1011.
-
(2017)
Cell
, vol.169
, pp. 1000-1011
-
-
He, S.1
Sharpless, N.E.2
-
47
-
-
70349859881
-
DNA damage, aging, and cancer
-
Hoeijmakers, J.H., DNA damage, aging, and cancer. N. Engl. J. Med. 361 (2009), 1475–1485.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
48
-
-
84885869718
-
Changes in splicing factor expression are associated with advancing age in man
-
Holly, A.C., Melzer, D., Pilling, L.C., Fellows, A.C., Tanaka, T., Ferrucci, L., Harries, L.W., Changes in splicing factor expression are associated with advancing age in man. Mech. Ageing Dev. 134 (2013), 356–366.
-
(2013)
Mech. Ageing Dev.
, vol.134
, pp. 356-366
-
-
Holly, A.C.1
Melzer, D.2
Pilling, L.C.3
Fellows, A.C.4
Tanaka, T.5
Ferrucci, L.6
Harries, L.W.7
-
49
-
-
84874999665
-
The role of inflammation in age-related disease
-
Howcroft, T.K., Campisi, J., Louis, G.B., Smith, M.T., Wise, B., Wyss-Coray, T., Augustine, A.D., McElhaney, J.E., Kohanski, R., Sierra, F., The role of inflammation in age-related disease. Aging 5 (2013), 84–93.
-
(2013)
Aging
, vol.5
, pp. 84-93
-
-
Howcroft, T.K.1
Campisi, J.2
Louis, G.B.3
Smith, M.T.4
Wise, B.5
Wyss-Coray, T.6
Augustine, A.D.7
McElhaney, J.E.8
Kohanski, R.9
Sierra, F.10
-
50
-
-
84866442827
-
Review: a meta-analysis of GWAS and age-associated diseases
-
Jeck, W.R., Siebold, A.P., Sharpless, N.E., Review: a meta-analysis of GWAS and age-associated diseases. Aging Cell 11 (2012), 727–731.
-
(2012)
Aging Cell
, vol.11
, pp. 727-731
-
-
Jeck, W.R.1
Siebold, A.P.2
Sharpless, N.E.3
-
51
-
-
84903485542
-
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
-
Jurk, D., Wilson, C., Passos, J.F., Oakley, F., Correia-Melo, C., Greaves, L., Saretzki, G., Fox, C., Lawless, C., Anderson, R. et al., Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat. Commun., 2, 2014, 4172.
-
(2014)
Nat. Commun.
, vol.2
, pp. 4172
-
-
Jurk, D.1
Wilson, C.2
Passos, J.F.3
Oakley, F.4
Correia-Melo, C.5
Greaves, L.6
Saretzki, G.7
Fox, C.8
Lawless, C.9
Anderson, R.10
-
52
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi, Y., Naiman, S., Amir, G., Peshti, V., Zinman, G., Nahum, L., Bar-Joseph, Z., Cohen, H.Y., The sirtuin SIRT6 regulates lifespan in male mice. Nature 483 (2012), 218–221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
53
-
-
84942456107
-
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
-
(aaa5612)
-
Kang, C., Xu, Q., Martin, T.D., Li, M.Z., Demaria, M., Aron, L., Lu, T., Yankner, B.A., Campisi, J., Elledge, S.J., The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. Science, 349, 2015 (aaa5612).
-
(2015)
Science
, vol.349
-
-
Kang, C.1
Xu, Q.2
Martin, T.D.3
Li, M.Z.4
Demaria, M.5
Aron, L.6
Lu, T.7
Yankner, B.A.8
Campisi, J.9
Elledge, S.J.10
-
54
-
-
84910029849
-
Geroscience: linking aging to chronic disease
-
Kennedy, B.K., Berger, S.L., Brunet, A., Campisi, J., Cuervo, A.M., Epel, E.S., Franceschi, C., Lithgow, G.J., Morimoto, R.I., Pessin, J.E. et al., Geroscience: linking aging to chronic disease. Cell 159 (2014), 709–713.
-
(2014)
Cell
, vol.159
, pp. 709-713
-
-
Kennedy, B.K.1
Berger, S.L.2
Brunet, A.3
Campisi, J.4
Cuervo, A.M.5
Epel, E.S.6
Franceschi, C.7
Lithgow, G.J.8
Morimoto, R.I.9
Pessin, J.E.10
-
55
-
-
84859336968
-
Inflammatory pathway genes belong to major targets of persistent organic pollutants in adipose cells
-
Kim, M.J., Pelloux, V., Guyot, E., Tordjman, J., Bui, L.C., Chevallier, A., Forest, C., Benelli, C., Clement, K., Barouki, R., Inflammatory pathway genes belong to major targets of persistent organic pollutants in adipose cells. Environ. Health Perspect. 120 (2012), 508–514.
-
(2012)
Environ. Health Perspect.
, vol.120
, pp. 508-514
-
-
Kim, M.J.1
Pelloux, V.2
Guyot, E.3
Tordjman, J.4
Bui, L.C.5
Chevallier, A.6
Forest, C.7
Benelli, C.8
Clement, K.9
Barouki, R.10
-
56
-
-
79251498807
-
Protein homeostasis and aging: the importance of exquisite quality control
-
Koga, H., Kaushik, S., Cuervo, A.M., Protein homeostasis and aging: the importance of exquisite quality control. Ageing Res. Rev. 10 (2011), 205–215.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 205-215
-
-
Koga, H.1
Kaushik, S.2
Cuervo, A.M.3
-
57
-
-
34548437394
-
A life course approach to healthy aging, frailty, and capability
-
Kuh, D., New Dynamics of Ageing Preparatory, N., A life course approach to healthy aging, frailty, and capability. J. Gerontol. A Biol. Sci. Med. Sci. 62 (2007), 717–721.
-
(2007)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.62
, pp. 717-721
-
-
Kuh, D.1
New Dynamics of Ageing Preparatory, N.2
-
58
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G.C., Hiona, A., Pugh, T.D., Someya, S., Panzer, K., Wohlgemuth, S.E., Hofer, T., Seo, A.Y., Sullivan, R., Jobling, W.A. et al., Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309 (2005), 481–484.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
59
-
-
84924358856
-
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
-
Lee, C., Zeng, J., Drew, B.G., Sallam, T., Martin-Montalvo, A., Wan, J., Kim, S.J., Mehta, H., Hevener, A.L., de Cabo, R. et al., The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 21 (2015), 443–454.
-
(2015)
Cell Metab.
, vol.21
, pp. 443-454
-
-
Lee, C.1
Zeng, J.2
Drew, B.G.3
Sallam, T.4
Martin-Montalvo, A.5
Wan, J.6
Kim, S.J.7
Mehta, H.8
Hevener, A.L.9
de Cabo, R.10
-
60
-
-
84988014743
-
Gene-environment interactions linking air pollution and inflammation in Parkinson's disease
-
Lee, P.C., Raaschou-Nielsen, O., Lill, C.M., Bertram, L., Sinsheimer, J.S., Hansen, J., Ritz, B., Gene-environment interactions linking air pollution and inflammation in Parkinson's disease. Environ. Res. 151 (2016), 713–720.
-
(2016)
Environ. Res.
, vol.151
, pp. 713-720
-
-
Lee, P.C.1
Raaschou-Nielsen, O.2
Lill, C.M.3
Bertram, L.4
Sinsheimer, J.S.5
Hansen, J.6
Ritz, B.7
-
61
-
-
17144392613
-
Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women
-
Leng, S., Xue, Q.L., Huang, Y., Semba, R., Chaves, P., Bandeen-Roche, K., Fried, L., Walston, J., Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women. J. Gerontol. A Biol. Sci. Med. Sci. 60 (2005), 195–199.
-
(2005)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.60
, pp. 195-199
-
-
Leng, S.1
Xue, Q.L.2
Huang, Y.3
Semba, R.4
Chaves, P.5
Bandeen-Roche, K.6
Fried, L.7
Walston, J.8
-
62
-
-
34347338725
-
Inflammation and frailty in older women
-
Leng, S.X., Xue, Q.L., Tian, J., Walston, J.D., Fried, L.P., Inflammation and frailty in older women. J. Am. Geriatr. Soc. 55 (2007), 864–871.
-
(2007)
J. Am. Geriatr. Soc.
, vol.55
, pp. 864-871
-
-
Leng, S.X.1
Xue, Q.L.2
Tian, J.3
Walston, J.D.4
Fried, L.P.5
-
63
-
-
84919385246
-
Whole blood gene expression and interleukin-6 levels
-
Lin, H., Joehanes, R., Pilling, L.C., Dupuis, J., Lunetta, K.L., Ying, S.X., Benjamin, E.J., Hernandez, D., Singleton, A., Melzer, D. et al., Whole blood gene expression and interleukin-6 levels. Genomics 104 (2014), 490–495.
-
(2014)
Genomics
, vol.104
, pp. 490-495
-
-
Lin, H.1
Joehanes, R.2
Pilling, L.C.3
Dupuis, J.4
Lunetta, K.L.5
Ying, S.X.6
Benjamin, E.J.7
Hernandez, D.8
Singleton, A.9
Melzer, D.10
-
64
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M.A., Partridge, L., Serrano, M., Kroemer, G., The hallmarks of aging. Cell 153 (2013), 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
65
-
-
84981312038
-
Metabolic control of longevity
-
Lopez-Otin, C., Galluzzi, L., Freije, J.M.P., Madeo, F., Kroemer, G., Metabolic control of longevity. Cell 166 (2016), 802–821.
-
(2016)
Cell
, vol.166
, pp. 802-821
-
-
Lopez-Otin, C.1
Galluzzi, L.2
Freije, J.M.P.3
Madeo, F.4
Kroemer, G.5
-
66
-
-
0038600735
-
Aging affects the engagement of the hippocampus during autobiographical memory retrieval
-
Maguire, E.A., Frith, C.D., Aging affects the engagement of the hippocampus during autobiographical memory retrieval. Brain J. Neurol. 126 (2003), 1511–1523.
-
(2003)
Brain J. Neurol.
, vol.126
, pp. 1511-1523
-
-
Maguire, E.A.1
Frith, C.D.2
-
67
-
-
33748797136
-
Genes, environment and the value of prospective cohort studies
-
Manolio, T.A., Bailey-Wilson, J.E., Collins, F.S., Genes, environment and the value of prospective cohort studies. Nat. Rev. Genet. 7 (2006), 812–820.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 812-820
-
-
Manolio, T.A.1
Bailey-Wilson, J.E.2
Collins, F.S.3
-
68
-
-
80052340001
-
Aging with multimorbidity: a systematic review of the literature
-
Marengoni, A., Angleman, S., Melis, R., Mangialasche, F., Karp, A., Garmen, A., Meinow, B., Fratiglioni, L., Aging with multimorbidity: a systematic review of the literature. Ageing Res. Rev. 10 (2011), 430–439.
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 430-439
-
-
Marengoni, A.1
Angleman, S.2
Melis, R.3
Mangialasche, F.4
Karp, A.5
Garmen, A.6
Meinow, B.7
Fratiglioni, L.8
-
69
-
-
80051699548
-
Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production
-
Matsumoto, M., Kurihara, S., Kibe, R., Ashida, H., Benno, Y., Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production. PLoS One, 6, 2011, e23652.
-
(2011)
PLoS One
, vol.6
-
-
Matsumoto, M.1
Kurihara, S.2
Kibe, R.3
Ashida, H.4
Benno, Y.5
-
70
-
-
84858157217
-
The senescence accelerated mouse (SAMP8) as a model for oxidative stress and Alzheimer's disease
-
Morley, J.E., Armbrecht, H.J., Farr, S.A., Kumar, V.B., The senescence accelerated mouse (SAMP8) as a model for oxidative stress and Alzheimer's disease. Biochim. Biophys. Acta 1822 (2012), 650–656.
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 650-656
-
-
Morley, J.E.1
Armbrecht, H.J.2
Farr, S.A.3
Kumar, V.B.4
-
71
-
-
84904746130
-
Inflamm-aging does not simply reflect increases in pro-inflammatory markers
-
Morrisette-Thomas, V., Cohen, A.A., Fulop, T., Riesco, E., Legault, V., Li, Q., Milot, E., Dusseault-Belanger, F., Ferrucci, L., Inflamm-aging does not simply reflect increases in pro-inflammatory markers. Mech. Ageing Dev. 139 (2014), 49–57.
-
(2014)
Mech. Ageing Dev.
, vol.139
, pp. 49-57
-
-
Morrisette-Thomas, V.1
Cohen, A.A.2
Fulop, T.3
Riesco, E.4
Legault, V.5
Li, Q.6
Milot, E.7
Dusseault-Belanger, F.8
Ferrucci, L.9
-
72
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky, R., Chua, K.F., Lombard, D.B., Pang, W.W., Fischer, M.R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M.M. et al., Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124 (2006), 315–329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
-
73
-
-
85044159009
-
The National Academies Keck Futures Initiative: The Future of Human Healthspan: Demography, Evolution, Medicine, and Bioengineering, Task Group Summaries
-
The National Academies Press Washington, DC
-
National Research Council, The National Academies Keck Futures Initiative: The Future of Human Healthspan: Demography, Evolution, Medicine, and Bioengineering, Task Group Summaries. 2008, The National Academies Press, Washington, DC.
-
(2008)
-
-
National Research Council1
-
74
-
-
84964555395
-
Modulation of inflammation by autophagy: consequences for human disease
-
Netea-Maier, R.T., Plantinga, T.S., van de Veerdonk, F.L., Smit, J.W., Netea, M.G., Modulation of inflammation by autophagy: consequences for human disease. Autophagy 12 (2016), 245–260.
-
(2016)
Autophagy
, vol.12
, pp. 245-260
-
-
Netea-Maier, R.T.1
Plantinga, T.S.2
van de Veerdonk, F.L.3
Smit, J.W.4
Netea, M.G.5
-
75
-
-
84872733391
-
Review: microglia of the aged brain: primed to be activated and resistant to regulation
-
Norden, D.M., Godbout, J.P., Review: microglia of the aged brain: primed to be activated and resistant to regulation. Neuropathol. Appl. Neurobiol. 39 (2013), 19–34.
-
(2013)
Neuropathol. Appl. Neurobiol.
, vol.39
, pp. 19-34
-
-
Norden, D.M.1
Godbout, J.P.2
-
76
-
-
84888197753
-
MicroRNAs linking inflamm-aging, cellular senescence and cancer
-
Olivieri, F., Rippo, M.R., Monsurro, V., Salvioli, S., Capri, M., Procopio, A.D., Franceschi, C., MicroRNAs linking inflamm-aging, cellular senescence and cancer. Ageing Res. Rev. 12 (2013), 1056–1068.
-
(2013)
Ageing Res. Rev.
, vol.12
, pp. 1056-1068
-
-
Olivieri, F.1
Rippo, M.R.2
Monsurro, V.3
Salvioli, S.4
Capri, M.5
Procopio, A.D.6
Franceschi, C.7
-
77
-
-
84874271499
-
omega-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
-
O'Rourke, E.J., Kuballa, P., Xavier, R., Ruvkun, G., omega-6 Polyunsaturated fatty acids extend life span through the activation of autophagy. Genes Dev. 27 (2013), 429–440.
-
(2013)
Genes Dev.
, vol.27
, pp. 429-440
-
-
O'Rourke, E.J.1
Kuballa, P.2
Xavier, R.3
Ruvkun, G.4
-
78
-
-
84862976890
-
Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-kappaB
-
Paul, S., Kashyap, A.K., Jia, W., He, Y.W., Schaefer, B.C., Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-kappaB. Immunity 36 (2012), 947–958.
-
(2012)
Immunity
, vol.36
, pp. 947-958
-
-
Paul, S.1
Kashyap, A.K.2
Jia, W.3
He, Y.W.4
Schaefer, B.C.5
-
79
-
-
84959538848
-
Body composition assessment and nutritional status evaluation in men and women Portuguese centenarians
-
Pereira da Silva, A., Matos, A., Valente, A., Gil, A., Alonso, I., Ribeiro, R., Bicho, M., Gorjao-Clara, J., Body composition assessment and nutritional status evaluation in men and women Portuguese centenarians. J. Nutr. Health Aging 20 (2016), 256–266.
-
(2016)
J. Nutr. Health Aging
, vol.20
, pp. 256-266
-
-
Pereira da Silva, A.1
Matos, A.2
Valente, A.3
Gil, A.4
Alonso, I.5
Ribeiro, R.6
Bicho, M.7
Gorjao-Clara, J.8
-
80
-
-
84945143930
-
The transcriptional landscape of age in human peripheral blood
-
Peters, M.J., Joehanes, R., Pilling, L.C., Schurmann, C., Conneely, K.N., Powell, J., Reinmaa, E., Sutphin, G.L., Zhernakova, A., Schramm, K. et al., The transcriptional landscape of age in human peripheral blood. Nat. Commun., 6, 2015, 8570.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8570
-
-
Peters, M.J.1
Joehanes, R.2
Pilling, L.C.3
Schurmann, C.4
Conneely, K.N.5
Powell, J.6
Reinmaa, E.7
Sutphin, G.L.8
Zhernakova, A.9
Schramm, K.10
-
81
-
-
84938906516
-
Gene expression markers of age-related inflammation in two human cohorts
-
Pilling, L.C., Joehanes, R., Melzer, D., Harries, L.W., Henley, W., Dupuis, J., Lin, H., Mitchell, M., Hernandez, D., Ying, S.X. et al., Gene expression markers of age-related inflammation in two human cohorts. Exp. Gerontol. 70 (2015), 37–45.
-
(2015)
Exp. Gerontol.
, vol.70
, pp. 37-45
-
-
Pilling, L.C.1
Joehanes, R.2
Melzer, D.3
Harries, L.W.4
Henley, W.5
Dupuis, J.6
Lin, H.7
Mitchell, M.8
Hernandez, D.9
Ying, S.X.10
-
82
-
-
67650410543
-
Biological and chemical approaches to diseases of proteostasis deficiency
-
Powers, E.T., Morimoto, R.I., Dillin, A., Kelly, J.W., Balch, W.E., Biological and chemical approaches to diseases of proteostasis deficiency. Annu. Rev. Biochem. 78 (2009), 959–991.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 959-991
-
-
Powers, E.T.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
Balch, W.E.5
-
83
-
-
34247613108
-
Brain aging and its modifiers: insights from in vivo neuromorphometry and susceptibility weighted imaging
-
Raz, N., Rodrigue, K.M., Haacke, E.M., Brain aging and its modifiers: insights from in vivo neuromorphometry and susceptibility weighted imaging. Ann. N. Y. Acad. Sci. 1097 (2007), 84–93.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1097
, pp. 84-93
-
-
Raz, N.1
Rodrigue, K.M.2
Haacke, E.M.3
-
84
-
-
77949371211
-
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the ‘hygiene’ or ‘old friends’ hypothesis
-
Rook, G.A., 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the ‘hygiene’ or ‘old friends’ hypothesis. Clin. Exp. Immunol. 160 (2010), 70–79.
-
(2010)
Clin. Exp. Immunol.
, vol.160
, pp. 70-79
-
-
Rook, G.A.1
-
85
-
-
80052303130
-
Autophagy and aging
-
Rubinsztein, D.C., Marino, G., Kroemer, G., Autophagy and aging. Cell 146 (2011), 682–695.
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marino, G.2
Kroemer, G.3
-
86
-
-
33646905903
-
The endeavor of high maintenance homeostasis: resting metabolic rate and the legacy of longevity
-
Ruggiero, C., Ferrucci, L., The endeavor of high maintenance homeostasis: resting metabolic rate and the legacy of longevity. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006), 466–471.
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 466-471
-
-
Ruggiero, C.1
Ferrucci, L.2
-
87
-
-
84942115958
-
Metformin and inflammation: its potential beyond glucose-lowering effect
-
Saisho, Y., Metformin and inflammation: its potential beyond glucose-lowering effect. Endocr Metab Immune Disord Drug Targets 15 (2015), 196–205.
-
(2015)
Endocr Metab Immune Disord Drug Targets
, vol.15
, pp. 196-205
-
-
Saisho, Y.1
-
88
-
-
85021792527
-
Shaping proteostasis at the cellular, tissue, and organismal level
-
Sala, A.J., Bott, L.C., Morimoto, R.I., Shaping proteostasis at the cellular, tissue, and organismal level. J. Cell Biol. 216 (2017), 1231–1241.
-
(2017)
J. Cell Biol.
, vol.216
, pp. 1231-1241
-
-
Sala, A.J.1
Bott, L.C.2
Morimoto, R.I.3
-
89
-
-
84863329778
-
Inflammaging: disturbed interplay between autophagy and inflammasomes
-
Salminen, A., Kaarniranta, K., Kauppinen, A., Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging 4 (2012), 166–175.
-
(2012)
Aging
, vol.4
, pp. 166-175
-
-
Salminen, A.1
Kaarniranta, K.2
Kauppinen, A.3
-
90
-
-
79955650634
-
The pro- and anti-inflammatory properties of the cytokine interleukin-6
-
Scheller, J., Chalaris, A., Schmidt-Arras, D., Rose-John, S., The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim. Biophys. Acta 1813 (2011), 878–888.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 878-888
-
-
Scheller, J.1
Chalaris, A.2
Schmidt-Arras, D.3
Rose-John, S.4
-
91
-
-
33847767040
-
Sarcopenic obesity and inflammation in the InCHIANTI study
-
Schrager, M.A., Metter, E.J., Simonsick, E., Ble, A., Bandinelli, S., Lauretani, F., Ferrucci, L., Sarcopenic obesity and inflammation in the InCHIANTI study. J. Appl. Physiol. (1985) 102 (2007), 919–925.
-
(2007)
J. Appl. Physiol. (1985)
, vol.102
, pp. 919-925
-
-
Schrager, M.A.1
Metter, E.J.2
Simonsick, E.3
Ble, A.4
Bandinelli, S.5
Lauretani, F.6
Ferrucci, L.7
-
92
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Schulz, T.J., Zarse, K., Voigt, A., Urban, N., Birringer, M., Ristow, M., Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 6 (2007), 280–293.
-
(2007)
Cell Metab.
, vol.6
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
93
-
-
84875953755
-
Stem cell metabolism in tissue development and aging
-
Shyh-Chang, N., Daley, G.Q., Cantley, L.C., Stem cell metabolism in tissue development and aging. Development 140 (2013), 2535–2547.
-
(2013)
Development
, vol.140
, pp. 2535-2547
-
-
Shyh-Chang, N.1
Daley, G.Q.2
Cantley, L.C.3
-
94
-
-
84895756413
-
Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity
-
Slyskova, J., Lorenzo, Y., Karlsen, A., Carlsen, M.H., Novosadova, V., Blomhoff, R., Vodicka, P., Collins, A.R., Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity. DNA Repair (Amst) 16 (2014), 66–73.
-
(2014)
DNA Repair (Amst)
, vol.16
, pp. 66-73
-
-
Slyskova, J.1
Lorenzo, Y.2
Karlsen, A.3
Carlsen, M.H.4
Novosadova, V.5
Blomhoff, R.6
Vodicka, P.7
Collins, A.R.8
-
95
-
-
70350425215
-
Polyamine-rich food decreases age-associated pathology and mortality in aged mice
-
Soda, K., Dobashi, Y., Kano, Y., Tsujinaka, S., Konishi, F., Polyamine-rich food decreases age-associated pathology and mortality in aged mice. Exp. Gerontol. 44 (2009), 727–732.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 727-732
-
-
Soda, K.1
Dobashi, Y.2
Kano, Y.3
Tsujinaka, S.4
Konishi, F.5
-
96
-
-
84984962740
-
Inflammation and frailty in the elderly: a systematic review and meta-analysis
-
Soysal, P., Stubbs, B., Lucato, P., Luchini, C., Solmi, M., Peluso, R., Sergi, G., Isik, A.T., Manzato, E., Maggi, S. et al., Inflammation and frailty in the elderly: a systematic review and meta-analysis. Ageing Res. Rev. 31 (2016), 1–8.
-
(2016)
Ageing Res. Rev.
, vol.31
, pp. 1-8
-
-
Soysal, P.1
Stubbs, B.2
Lucato, P.3
Luchini, C.4
Solmi, M.5
Peluso, R.6
Sergi, G.7
Isik, A.T.8
Manzato, E.9
Maggi, S.10
-
97
-
-
84922754618
-
Age-independent rise of inflammatory scores may contribute to accelerated aging in multi-morbidity
-
Stepanova, M., Rodriguez, E., Birerdinc, A., Baranova, A., Age-independent rise of inflammatory scores may contribute to accelerated aging in multi-morbidity. Oncotarget 6 (2015), 1414–1421.
-
(2015)
Oncotarget
, vol.6
, pp. 1414-1421
-
-
Stepanova, M.1
Rodriguez, E.2
Birerdinc, A.3
Baranova, A.4
-
98
-
-
85005978336
-
Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
-
Stout, M.B., Justice, J.N., Nicklas, B.J., Kirkland, J.L., Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty. Physiology 32 (2017), 9–19.
-
(2017)
Physiology
, vol.32
, pp. 9-19
-
-
Stout, M.B.1
Justice, J.N.2
Nicklas, B.J.3
Kirkland, J.L.4
-
99
-
-
84863181604
-
Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities
-
Tomaru, U., Takahashi, S., Ishizu, A., Miyatake, Y., Gohda, A., Suzuki, S., Ono, A., Ohara, J., Baba, T., Murata, S. et al., Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities. Am. J. Pathol. 180 (2012), 963–972.
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 963-972
-
-
Tomaru, U.1
Takahashi, S.2
Ishizu, A.3
Miyatake, Y.4
Gohda, A.5
Suzuki, S.6
Ono, A.7
Ohara, J.8
Baba, T.9
Murata, S.10
-
100
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J.N., Rovio, A.T., Bruder, C.E., Bohlooly, Y.M., Gidlof, S., Oldfors, A., Wibom, R. et al., Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429 (2004), 417–423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
-
101
-
-
41349087783
-
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
-
Vermulst, M., Wanagat, J., Kujoth, G.C., Bielas, J.H., Rabinovitch, P.S., Prolla, T.A., Loeb, L.A., DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. Nat. Genet. 40 (2008), 392–394.
-
(2008)
Nat. Genet.
, vol.40
, pp. 392-394
-
-
Vermulst, M.1
Wanagat, J.2
Kujoth, G.C.3
Bielas, J.H.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
102
-
-
85044099118
-
An international perspective on chronic multimorbidity: approaching the elephant in the room
-
PubMed: [Epub ahead of print]
-
Vetrano, D.L., Calderon-Larranaga, A., Marengoni, A., Onder, G., Bauer, J.M., Cesari, M., Ferrucci, L., Fratiglioni, L., An international perspective on chronic multimorbidity: approaching the elephant in the room. J. Gerontol. A Biol. Sci. Med. Sci., 2017 PubMed: [Epub ahead of print].
-
(2017)
J. Gerontol. A Biol. Sci. Med. Sci.
-
-
Vetrano, D.L.1
Calderon-Larranaga, A.2
Marengoni, A.3
Onder, G.4
Bauer, J.M.5
Cesari, M.6
Ferrucci, L.7
Fratiglioni, L.8
-
103
-
-
84948953210
-
Mitochondrial dysfunction and longevity in animals: untangling the knot
-
Wang, Y., Hekimi, S., Mitochondrial dysfunction and longevity in animals: untangling the knot. Science 350 (2015), 1204–1207.
-
(2015)
Science
, vol.350
, pp. 1204-1207
-
-
Wang, Y.1
Hekimi, S.2
-
104
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
Wang, C., Jurk, D., Maddick, M., Nelson, G., Martin-Ruiz, C., von Zglinicki, T., DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 8 (2009), 311–323.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
Nelson, G.4
Martin-Ruiz, C.5
von Zglinicki, T.6
-
105
-
-
84907463613
-
NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease
-
Wang, L., Qu, P., Zhao, J., Chang, Y., NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease. Arch. Med. Sci. AMS 10 (2014), 791–800.
-
(2014)
Arch. Med. Sci. AMS
, vol.10
, pp. 791-800
-
-
Wang, L.1
Qu, P.2
Zhao, J.3
Chang, Y.4
-
106
-
-
85021722908
-
Factors influencing the gut microbiota, inflammation, and type 2 diabetes
-
Wen, L., Duffy, A., Factors influencing the gut microbiota, inflammation, and type 2 diabetes. J. Nutr. 147 (2017), 1468S–1475S.
-
(2017)
J. Nutr.
, vol.147
, pp. 1468S-1475S
-
-
Wen, L.1
Duffy, A.2
-
107
-
-
34248513736
-
Report of the national institute on aging task force on comorbidity
-
Yancik, R., Ershler, W., Satariano, W., Hazzard, W., Cohen, H.J., Ferrucci, L., Report of the national institute on aging task force on comorbidity. J. Gerontol. A Biol. Sci. Med. Sci. 62 (2007), 275–280.
-
(2007)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.62
, pp. 275-280
-
-
Yancik, R.1
Ershler, W.2
Satariano, W.3
Hazzard, W.4
Cohen, H.J.5
Ferrucci, L.6
-
108
-
-
84878766631
-
Mechanisms that match ATP supply to demand in cardiac pacemaker cells during high ATP demand
-
Yaniv, Y., Spurgeon, H.A., Ziman, B.D., Lyashkov, A.E., Lakatta, E.G., Mechanisms that match ATP supply to demand in cardiac pacemaker cells during high ATP demand. Am. J. Physiol. Heart Circ. Physiol. 304 (2013), H1428–1438.
-
(2013)
Am. J. Physiol. Heart Circ. Physiol.
, vol.304
, pp. H1428-1438
-
-
Yaniv, Y.1
Spurgeon, H.A.2
Ziman, B.D.3
Lyashkov, A.E.4
Lakatta, E.G.5
-
109
-
-
84884350730
-
NLRP3 inflammasomes show high expression in aorta of patients with atherosclerosis
-
Zheng, F., Xing, S., Gong, Z., Xing, Q., NLRP3 inflammasomes show high expression in aorta of patients with atherosclerosis. Heart Lung Circ. 22 (2013), 746–750.
-
(2013)
Heart Lung Circ.
, vol.22
, pp. 746-750
-
-
Zheng, F.1
Xing, S.2
Gong, Z.3
Xing, Q.4
-
110
-
-
84948436225
-
Circadian clock control by polyamine levels through a mechanism that declines with age
-
Zwighaft, Z., Aviram, R., Shalev, M., Rousso-Noori, L., Kraut-Cohen, J., Golik, M., Brandis, A., Reinke, H., Aharoni, A., Kahana, C. et al., Circadian clock control by polyamine levels through a mechanism that declines with age. Cell Metab. 22 (2015), 874–885.
-
(2015)
Cell Metab.
, vol.22
, pp. 874-885
-
-
Zwighaft, Z.1
Aviram, R.2
Shalev, M.3
Rousso-Noori, L.4
Kraut-Cohen, J.5
Golik, M.6
Brandis, A.7
Reinke, H.8
Aharoni, A.9
Kahana, C.10
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