The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Cell Metabolism

Volumn 21, Issue 3, 2015, Pages 443-454

  Lee, Changhan ^a   Zeng, Jennifer ^a   Drew, Brian G ^b   Sallam, Tamer ^b   Martin Montalvo, Alejandro ^c   Wan, Junxiang ^a   Kim, Su Jeong ^a   Mehta, Hemal ^a   Hevener, Andrea L ^b   De Cabo, Rafael ^c   Cohen, Pinchas ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ANTIDIABETIC AGENT; FOLIC ACID; GLUCOSE TRANSPORTER 4; INSULIN; METFORMIN; MITOCHONDRIAL OPEN READING FRAME OF THE 12S RRNA C; PEPTIDE; RNA 12S; UNCLASSIFIED DRUG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOCHONDRIAL DNA; POLYPEPTIDE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DIET INDUCED OBESITY; ENERGY METABOLISM; ENZYME ACTIVATION; FATTY ACID METABOLISM; GENE EXPRESSION; HEK293 CELL LINE; HOMEOSTASIS; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC PARAMETERS; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OBESITY; OPEN READING FRAME; PRIORITY JOURNAL; PURINE SYNTHESIS; SKELETAL MUSCLE; TARGET ORGAN; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; HELA CELL LINE; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

MUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; CELL LINE, TUMOR; DIET, HIGH-FAT; DNA, MITOCHONDRIAL; HEK293 CELLS; HELA CELLS; HOMEOSTASIS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MITOCHONDRIA; MUSCLE, SKELETAL; OBESITY; PEPTIDES; SIGNAL TRANSDUCTION;

EID: 84924358856     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.02.009     Document Type: Article

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