-
2
-
-
77957329119
-
Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli
-
Ajikumar PK, Xiao WH, Tyo KE, Wang Y, Simeon F, Leonard E, Mucha O, Phon TH, Pfeifer B, Stephanopoulos G. Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 2010;330:70-4.
-
(2010)
Science
, vol.330
, pp. 70-74
-
-
Ajikumar, P.K.1
Xiao, W.H.2
Tyo, K.E.3
Wang, Y.4
Simeon, F.5
Leonard, E.6
Mucha, O.7
Phon, T.H.8
Pfeifer, B.9
Stephanopoulos, G.10
-
3
-
-
79952900480
-
Molecular activities, biosynthesis and evolution of triterpenoid saponins
-
Augustin JM, Kuzina V, Andersen SB, Bak S. Molecular activities, biosynthesis and evolution of triterpenoid saponins. Phytochemistry 2011;72:435-57.
-
(2011)
Phytochemistry
, vol.72
, pp. 435-457
-
-
Augustin, J.M.1
Kuzina, V.2
Andersen, S.B.3
Bak, S.4
-
4
-
-
84877256074
-
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols
-
Avalos JL, Fink GR, Stephanopoulos G. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat Biotechnol 2013;31:335-41.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 335-341
-
-
Avalos, J.L.1
Fink, G.R.2
Stephanopoulos, G.3
-
5
-
-
0001177042
-
Heterotrophic production of long-chain omega-3-fatty-acids utilizing algae and algae-like microorganisms
-
Barclay WR, Meager KM, Abril JR. Heterotrophic production of long-chain omega-3-fatty-acids utilizing algae and algae-like microorganisms. J Appl Phycol 1994;6:123-9.
-
(1994)
J Appl Phycol
, vol.6
, pp. 123-129
-
-
Barclay, W.R.1
Meager, K.M.2
Abril, J.R.3
-
6
-
-
1642401219
-
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol
-
Becker JV, Armstrong GO, van der Merwe MJ, Lambrechts MG, Vivier MA, Pretorius IS. Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol. FEMS Yeast Res 2003;4:79-85.
-
(2003)
FEMS Yeast Res
, vol.4
, pp. 79-85
-
-
Becker, J.V.1
Armstrong, G.O.2
van der Merwe, M.J.3
Lambrechts, M.G.4
Vivier, M.A.5
Pretorius, I.S.6
-
7
-
-
33747371394
-
Production of resveratrol in recombinant microorganisms
-
Beekwilder J, Wolswinkel R, Jonker H, Hall R, de Vos CH, Bovy A. Production of resveratrol in recombinant microorganisms. Appl Environ Microbiol 2006;72:5670-2.
-
(2006)
Appl Environ Microbiol
, vol.72
, pp. 5670-5672
-
-
Beekwilder, J.1
Wolswinkel, R.2
Jonker, H.3
Hall, R.4
de Vos, C.H.5
Bovy, A.6
-
8
-
-
0033230281
-
Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis
-
Bouwmeester HJ, Wallaart TE, Janssen MH, van Loo B, Jansen BJ, Posthumus MA, Schmidt CO, De Kraker JW, Konig WA, Franssen MC. Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis. Phytochemistry 1999;52:843-54.
-
(1999)
Phytochemistry
, vol.52
, pp. 843-854
-
-
Bouwmeester, H.J.1
Wallaart, T.E.2
Janssen, M.H.3
van Loo, B.4
Jansen, B.J.5
Posthumus, M.A.6
Schmidt, C.O.7
De Kraker, J.W.8
Konig, W.A.9
Franssen, M.C.10
-
9
-
-
38349167527
-
Biosynthesis of vitamin C by yeast leads to increased stress resistance
-
Branduardi P, Fossati T, Sauer M, Pagani R, Mattanovich D, Porro D. Biosynthesis of vitamin C by yeast leads to increased stress resistance. PLoS ONE 2007;2:e1092.
-
(2007)
PLoS ONE
, vol.2
-
-
Branduardi, P.1
Fossati, T.2
Sauer, M.3
Pagani, R.4
Mattanovich, D.5
Porro, D.6
-
11
-
-
33751120932
-
Production of isoprenoid pharmaceuticals by engineered microbes
-
Chang MC, Keasling JD. Production of isoprenoid pharmaceuticals by engineered microbes. Nat Chem Biol 2006;2: 674-81.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 674-681
-
-
Chang, M.C.1
Keasling, J.D.2
-
12
-
-
45849101241
-
Production platforms for the molecular pharming of alkaloid diversity
-
Chappell J. Production platforms for the molecular pharming of alkaloid diversity. P Natl Acad Sci USA 2008;105:7897-8.
-
(2008)
P Natl Acad Sci USA
, vol.105
, pp. 7897-7898
-
-
Chappell, J.1
-
13
-
-
0019035019
-
Silicone rubber and natural rubber as biomaterials
-
Courtney JM, Gilchrist T. Silicone rubber and natural rubber as biomaterials. Med Biol Eng Comput 1980;18:538-40.
-
(1980)
Med Biol Eng Comput
, vol.18
, pp. 538-540
-
-
Courtney, J.M.1
Gilchrist, T.2
-
14
-
-
78649992803
-
Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Salvia miltiorrhiza involved in diterpenoid tanshinone accumulation
-
Dai Z, Cui G, Zhou SF, Zhang X, Huang L. Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Salvia miltiorrhiza involved in diterpenoid tanshinone accumulation. J Plant Physiol 2011;168: 148-57.
-
(2011)
J Plant Physiol
, vol.168
, pp. 148-157
-
-
Dai, Z.1
Cui, G.2
Zhou, S.F.3
Zhang, X.4
Huang, L.5
-
15
-
-
84866744325
-
Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae
-
Dai Z, Liu Y, Huang L, Zhang X. Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae. Biotechnol Bioeng 2012;109:2845-53.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 2845-2853
-
-
Dai, Z.1
Liu, Y.2
Huang, L.3
Zhang, X.4
-
16
-
-
84886486790
-
Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides
-
Dai Z, Liu Y, Zhang X, Shi M, Wang B, Wang D, Huang L. Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides. Metab Eng 2013;20:146-56.
-
(2013)
Metab Eng
, vol.20
, pp. 146-156
-
-
Dai, Z.1
Liu, Y.2
Zhang, X.3
Shi, M.4
Wang, B.5
Wang, D.6
Huang, L.7
-
17
-
-
84892747580
-
Producing aglycons of ginsenosides in bakers'yeast
-
Dai Z, Wang B, Liu Y, Shi M, Wang D, Zhang X, Liu T, Huang L. Producing aglycons of ginsenosides in bakers'yeast. Sci Rep 2014;4:3698.
-
(2014)
Sci Rep
, vol.4
, pp. 3698
-
-
Dai, Z.1
Wang, B.2
Liu, Y.3
Shi, M.4
Wang, D.5
Zhang, X.6
Liu, T.7
Huang, L.8
-
18
-
-
0030272217
-
Quality and authenticity of heterologous proteins synthesized in yeast
-
Eckart MR, Bussineau CM. Quality and authenticity of heterologous proteins synthesized in yeast. Curr Opin Biotechnol 1996;7:525-30.
-
(1996)
Curr Opin Biotechnol
, vol.7
, pp. 525-530
-
-
Eckart, M.R.1
Bussineau, C.M.2
-
19
-
-
44749083814
-
Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (paclitaxel) production
-
Engels B, Dahm P, Jennewein S. Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards taxol (paclitaxel) production. Metab Eng 2008;10:201-6.
-
(2008)
Metab Eng
, vol.10
, pp. 201-206
-
-
Engels, B.1
Dahm, P.2
Jennewein, S.3
-
20
-
-
84858070612
-
Synthetic biosystems for the production of high-value plant metabolites
-
Facchini PJ, Bohlmann J, Covello PS, De Luca V, Mahadevan R, Page JE, Ro DK, Sensen CW, Storms R, Martin VJJ. Synthetic biosystems for the production of high-value plant metabolites. Trends Biotechnol 2012;30:127-31.
-
(2012)
Trends Biotechnol
, vol.30
, pp. 127-131
-
-
Facchini, P.J.1
Bohlmann, J.2
Covello, P.S.3
De Luca, V.4
Mahadevan, R.5
Page, J.E.6
Ro, D.K.7
Sensen, C.W.8
Storms, R.9
Martin, V.J.J.10
-
21
-
-
80052030821
-
Harnessing yeast subcellular compartments for the production of plant terpenoids
-
Farhi M, Marhevka E, Masci T, Marcos E, Eyal Y, Ovadis M, Abeliovich H, Vainstein A. Harnessing yeast subcellular compartments for the production of plant terpenoids. Metab Eng 2011;13:474-81.
-
(2011)
Metab Eng
, vol.13
, pp. 474-481
-
-
Farhi, M.1
Marhevka, E.2
Masci, T.3
Marcos, E.4
Eyal, Y.5
Ovadis, M.6
Abeliovich, H.7
Vainstein, A.8
-
22
-
-
84910056833
-
Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae
-
Fossati E, Ekins A, Narcross L, Zhu Y, Falgueyret JP, Beaudoin GA, Facchini PJ, Martin VJ. Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae. Nat Commun 2014;5: 3283.
-
(2014)
Nat Commun
, vol.5
, pp. 3283
-
-
Fossati, E.1
Ekins, A.2
Narcross, L.3
Zhu, Y.4
Falgueyret, J.P.5
Beaudoin, G.A.6
Facchini, P.J.7
Martin, V.J.8
-
23
-
-
83255176933
-
CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis
-
Fukushima EO, Seki H, Ohyama K, Ono E, Umemoto N, Mizutani M, Saito K, Muranaka T. CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis. Plant Cell Physiol 2011;52:2050-61.
-
(2011)
Plant Cell Physiol
, vol.52
, pp. 2050-2061
-
-
Fukushima, E.O.1
Seki, H.2
Ohyama, K.3
Ono, E.4
Umemoto, N.5
Mizutani, M.6
Saito, K.7
Muranaka, T.8
-
24
-
-
70749152711
-
A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
-
Gao W, Hillwig ML, Huang L, Cui G, Wang X, Kong J, Yang B, Peters RJ. A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org Lett 2009;11: 5170-3.
-
(2009)
Org Lett
, vol.11
, pp. 5170-5173
-
-
Gao, W.1
Hillwig, M.L.2
Huang, L.3
Cui, G.4
Wang, X.5
Kong, J.6
Yang, B.7
Peters, R.J.8
-
25
-
-
84892945451
-
Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza
-
Gao W, Sun HX, Xiao H, et al. Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza. BMC Genomics 2014;15:73.
-
(2014)
BMC Genomics
, vol.15
, pp. 73
-
-
Gao, W.1
Sun, H.X.2
Xiao, H.3
-
26
-
-
84891857645
-
Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant
-
Gassel S, Breitenbach J, Sandmann G. Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant. Appl Microbiol Biotechnol 2014;98:345-50.
-
(2014)
Appl Microbiol Biotechnol
, vol.98
, pp. 345-350
-
-
Gassel, S.1
Breitenbach, J.2
Sandmann, G.3
-
27
-
-
0034892702
-
Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast
-
Geerlings A, Redondo FJ, Contin A, Memelink J, van der Heijden R, Verpoorte R. Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast. Appl Microbiol Biotechnol 2001;56:420-4.
-
(2001)
Appl Microbiol Biotechnol
, vol.56
, pp. 420-424
-
-
Geerlings, A.1
Redondo, F.J.2
Contin, A.3
Memelink, J.4
van der Heijden, R.5
Verpoorte, R.6
-
28
-
-
84883335229
-
Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants
-
Geisler K, Hughes RK, Sainsbury F, et al. Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants. P Natl Acad Sci USA 2013;110:E3360-7.
-
(2013)
P Natl Acad Sci USA
, vol.110
, pp. E3360-E3367
-
-
Geisler, K.1
Hughes, R.K.2
Sainsbury, F.3
-
29
-
-
77949493815
-
An engineered yeast efficiently secreting penicillin
-
Gidijala L, Kiel JA, Douma RD, Seifar RM, van Gulik WM, Bovenberg RA, Veenhuis M, van der Klei IJ. An engineered yeast efficiently secreting penicillin. PLoS ONE 2009;4:e8317.
-
(2009)
PLoS ONE
, vol.4
-
-
Gidijala, L.1
Kiel, J.A.2
Douma, R.D.3
Seifar, R.M.4
van Gulik, W.M.5
Bovenberg, R.A.6
Veenhuis, M.7
van der Klei, I.J.8
-
30
-
-
84874992963
-
Recent progress in the metabolic engineering of alkaloids in plant systems
-
Glenn WS, Runguphan W, O'Connor SE. Recent progress in the metabolic engineering of alkaloids in plant systems. Curr Opin Biotechnol 2013;24:354-65.
-
(2013)
Curr Opin Biotechnol
, vol.24
, pp. 354-365
-
-
Glenn, W.S.1
Runguphan, W.2
O'Connor, S.E.3
-
31
-
-
0034714532
-
Four years of post-genomic life with 6,000 yeast genes
-
Goffeau A. Four years of post-genomic life with 6,000 yeast genes. FEBS Lett 2000;480:37-41.
-
(2000)
FEBS Lett
, vol.480
, pp. 37-41
-
-
Goffeau, A.1
-
32
-
-
84871588130
-
Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species
-
Gongora-Castillo E, Childs KL, Fedewa G, et al. Development of transcriptomic resources for interrogating the biosynthesis of monoterpene indole alkaloids in medicinal plant species. PLoS ONE 2012;7:e52506.
-
(2012)
PLoS ONE
, vol.7
-
-
Gongora-Castillo, E.1
Childs, K.L.2
Fedewa, G.3
-
33
-
-
84867640507
-
Genomic approaches for interrogating the biochemistry of medicinal plant species
-
Gongora-Castillo E, Fedewa G, Yeo Y, Chappell J, DellaPenna D, Buell CR. Genomic approaches for interrogating the biochemistry of medicinal plant species. Methods Enzymol 2012;517:139-59.
-
(2012)
Methods Enzymol
, vol.517
, pp. 139-159
-
-
Gongora-Castillo, E.1
Fedewa, G.2
Yeo, Y.3
Chappell, J.4
DellaPenna, D.5
Buell, C.R.6
-
34
-
-
84880380223
-
CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
-
Guo J, Zhou YJ, Hillwig ML, et al. CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts. P Natl Acad Sci USA 2013;110:12108-13.
-
(2013)
P Natl Acad Sci USA
, vol.110
, pp. 12108-12113
-
-
Guo, J.1
Zhou, Y.J.2
Hillwig, M.L.3
-
35
-
-
83255165496
-
The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng
-
Han JY, Kim HJ, Kwon YS, Choi YE. The Cyt P450 enzyme CYP716A47 catalyzes the formation of protopanaxadiol from dammarenediol-II during ginsenoside biosynthesis in Panax ginseng. Plant Cell Physiol 2011;52:2062-73.
-
(2011)
Plant Cell Physiol
, vol.52
, pp. 2062-2073
-
-
Han, J.Y.1
Kim, H.J.2
Kwon, Y.S.3
Choi, Y.E.4
-
36
-
-
84866386264
-
Cytochrome P450 CYP716A53v2 catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis in Panax ginseng
-
Han JY, Hwang HS, Choi SW, Kim HJ, Choi YE. Cytochrome P450 CYP716A53v2 catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis in Panax ginseng. Plant Cell Physiol 2012;53:1535-45.
-
(2012)
Plant Cell Physiol
, vol.53
, pp. 1535-1545
-
-
Han, J.Y.1
Hwang, H.S.2
Choi, S.W.3
Kim, H.J.4
Choi, Y.E.5
-
37
-
-
49949088247
-
Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae
-
Hawkins KM, Smolke CD. Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. Nat Chem Biol 2008;4: 564-73.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 564-573
-
-
Hawkins, K.M.1
Smolke, C.D.2
-
38
-
-
0034862884
-
Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice
-
Hayashi H, Huang P, Kirakosyan A, Inoue K, Hiraoka N, Ikeshiro Y, Kushiro T, Shibuya M, Ebizuka Y. Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice. Biol Pharm Bull 2001;24:912-6.
-
(2001)
Biol Pharm Bull
, vol.24
, pp. 912-916
-
-
Hayashi, H.1
Huang, P.2
Kirakosyan, A.3
Inoue, K.4
Hiraoka, N.5
Ikeshiro, Y.6
Kushiro, T.7
Shibuya, M.8
Ebizuka, Y.9
-
39
-
-
0016291233
-
Recent progress in the biochemistry of plant steroids other than sterols (saponins, glycoalkaloids, pregnane derivatives, cardiac glycosides, and sex hormones)
-
Heftmann E. Recent progress in the biochemistry of plant steroids other than sterols (saponins, glycoalkaloids, pregnane derivatives, cardiac glycosides, and sex hormones). Lipids 1974;9:626-39.
-
(1974)
Lipids
, vol.9
, pp. 626-639
-
-
Heftmann, E.1
-
40
-
-
0029087870
-
Purification and characterization of taxa-4(5),11(12)-diene synthase from Pacific yew (Taxusbrevifolia) that catalyzes the first committed step of taxol biosynthesis
-
Hezari M, Lewis NG, Croteau R. Purification and characterization of taxa-4(5),11(12)-diene synthase from Pacific yew (Taxusbrevifolia) that catalyzes the first committed step of taxol biosynthesis. Arch Biochem Biophys 1995;322:437-44.
-
(1995)
Arch Biochem Biophys
, vol.322
, pp. 437-444
-
-
Hezari, M.1
Lewis, N.G.2
Croteau, R.3
-
41
-
-
0002511505
-
Astaxanthin from the yeast Phaffia rhodozyma
-
Johnson EA, Schroeder W. Astaxanthin from the yeast Phaffia rhodozyma. Stud Mycol 1995;38:81-90.
-
(1995)
Stud Mycol
, vol.38
, pp. 81-90
-
-
Johnson, E.A.1
Schroeder, W.2
-
43
-
-
38749148516
-
Synthetic biology for synthetic chemistry
-
Keasling JD. Synthetic biology for synthetic chemistry. ACS Chem Biol 2008;3:64-76.
-
(2008)
ACS Chem Biol
, vol.3
, pp. 64-76
-
-
Keasling, J.D.1
-
44
-
-
84859772410
-
Synthetic biology and the development of tools for metabolic engineering
-
Keasling JD. Synthetic biology and the development of tools for metabolic engineering. Metab Eng 2012;14:189-95.
-
(2012)
Metab Eng
, vol.14
, pp. 189-195
-
-
Keasling, J.D.1
-
46
-
-
56249130054
-
Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies
-
Lenihan JR, Tsuruta H, Diola D, Renninger NS, Regentin R. Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies. Biotechnol Prog 2008;24:1026-32.
-
(2008)
Biotechnol Prog
, vol.24
, pp. 1026-1032
-
-
Lenihan, J.R.1
Tsuruta, H.2
Diola, D.3
Renninger, N.S.4
Regentin, R.5
-
47
-
-
65349184006
-
Opportunities in metabolic engineering to facilitate scalable alkaloid production
-
Leonard E, Runguphan W, O'Connor S, Prather KJ. Opportunities in metabolic engineering to facilitate scalable alkaloid production. Nat Chem Biol 2009;5:292-300.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 292-300
-
-
Leonard, E.1
Runguphan, W.2
O'Connor, S.3
Prather, K.J.4
-
48
-
-
77956371200
-
Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control
-
Leonard E, Ajikumar PK, Thayer K, Xiao WH, Mo JD, Tidor B, Stephanopoulos G, Prather KL. Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control. P Natl Acad Sci USA 2010;107:13654-9.
-
(2010)
P Natl Acad Sci USA
, vol.107
, pp. 13654-13659
-
-
Leonard, E.1
Ajikumar, P.K.2
Thayer, K.3
Xiao, W.H.4
Mo, J.D.5
Tidor, B.6
Stephanopoulos, G.7
Prather, K.L.8
-
49
-
-
77953307436
-
Pharmacology of ginsenosides: a literature review
-
Leung KW, Wong AS. Pharmacology of ginsenosides: a literature review. Chin Med 2010;5:20.
-
(2010)
Chin Med
, vol.5
, pp. 20
-
-
Leung, K.W.1
Wong, A.S.2
-
50
-
-
84897073422
-
Heterologous production of plant-derived isoprenoid products in microbes and the application of metabolic engineering and synthetic biology
-
Li Y, Pfeifer BA. Heterologous production of plant-derived isoprenoid products in microbes and the application of metabolic engineering and synthetic biology. Curr Opin Plant Biol 2014;19C:8-13.
-
(2014)
Curr Opin Plant Biol
, vol.19 C
, pp. 8-13
-
-
Li, Y.1
Pfeifer, B.A.2
-
51
-
-
67650436176
-
Drug discovery and natural products: end of an era or an endless frontier?
-
Li JWH, Vederas JC. Drug discovery and natural products: end of an era or an endless frontier?. Science 2009;325:161-5.
-
(2009)
Science
, vol.325
, pp. 161-165
-
-
Li, J.W.H.1
Vederas, J.C.2
-
52
-
-
84880599354
-
Enhancing beta-carotene production in Saccharomyces cerevisiae by metabolic engineering
-
Li Q, Sun Z, Li J, Zhang Y. Enhancing beta-carotene production in Saccharomyces cerevisiae by metabolic engineering. FEMS Microbiol Lett 2013;345:94-101.
-
(2013)
FEMS Microbiol Lett
, vol.345
, pp. 94-101
-
-
Li, Q.1
Sun, Z.2
Li, J.3
Zhang, Y.4
-
53
-
-
84894534641
-
Synthetic biology in mammalian cells: next generation research tools and therapeutics
-
Lienert F, Lohmueller JJ, Garg A, Silver PA. Synthetic biology in mammalian cells: next generation research tools and therapeutics. Nat Rev Mol Cell Biol 2014;15:95-107.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 95-107
-
-
Lienert, F.1
Lohmueller, J.J.2
Garg, A.3
Silver, P.A.4
-
54
-
-
84872172091
-
Metabolic engineering of microorganisms for the synthesis of plant natural products
-
Marienhagen J, Bott M. Metabolic engineering of microorganisms for the synthesis of plant natural products. J Biotechnol 2013;163:166-78.
-
(2013)
J Biotechnol
, vol.163
, pp. 166-178
-
-
Marienhagen, J.1
Bott, M.2
-
55
-
-
84888012765
-
Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions
-
Markou G, Nerantzis E. Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions. Biotechnol Adv 2013;31: 1532-42.
-
(2013)
Biotechnol Adv
, vol.31
, pp. 1532-1542
-
-
Markou, G.1
Nerantzis, E.2
-
57
-
-
37049231086
-
On the anti-inflammatory mechanism of hydrocortisone (compound-F)
-
Menkin V. On the anti-inflammatory mechanism of hydrocortisone (compound-F). Science 1954;120:1026-8.
-
(1954)
Science
, vol.120
, pp. 1026-1028
-
-
Menkin, V.1
-
58
-
-
84857995434
-
Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform
-
Mikkelsen MD, Buron LD, Salomonsen B, Olsen CE, Hansen BG, Mortensen UH, Halkier BA. Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform. Metab Eng 2012;14:104-11.
-
(2012)
Metab Eng
, vol.14
, pp. 104-111
-
-
Mikkelsen, M.D.1
Buron, L.D.2
Salomonsen, B.3
Olsen, C.E.4
Hansen, B.G.5
Mortensen, U.H.6
Halkier, B.A.7
-
59
-
-
79957636478
-
Pathway engineering for functional isoprenoids
-
Misawa N. Pathway engineering for functional isoprenoids. Curr Opin Biotechnol 2011;22:627-33.
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 627-633
-
-
Misawa, N.1
-
60
-
-
84893351504
-
Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16alpha hydroxylase from Bupleurum falcatum
-
Moses T, Pollier J, Almagro L, Buyst D, Van Montagu M, Pedreno MA, Martins JC, Thevelein JM, Goossens A. Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16alpha hydroxylase from Bupleurum falcatum. P Natl Acad Sci USA 2014;111:1634-9.
-
(2014)
P Natl Acad Sci USA
, vol.111
, pp. 1634-1639
-
-
Moses, T.1
Pollier, J.2
Almagro, L.3
Buyst, D.4
Van Montagu, M.5
Pedreno, M.A.6
Martins, J.C.7
Thevelein, J.M.8
Goossens, A.9
-
61
-
-
48249155450
-
The leaf epidermome of Catharanthus roseus reveals its biochemical specialization
-
Murata J, Roepke J, Gordon H, De Luca V. The leaf epidermome of Catharanthus roseus reveals its biochemical specialization. Plant Cell 2008;20:524-42.
-
(2008)
Plant Cell
, vol.20
, pp. 524-542
-
-
Murata, J.1
Roepke, J.2
Gordon, H.3
De Luca, V.4
-
62
-
-
84859633021
-
A novel oral dosage formulation of the ginsenoside aglycone protopanaxadiol exhibits therapeutic activity against a hormone-insensitive model of prostate cancer
-
Musende AG, Eberding A, Wood CA, Adomat H, Fazli L, HurtadoColl A, Jia W, Bally MB, Guns EST. A novel oral dosage formulation of the ginsenoside aglycone protopanaxadiol exhibits therapeutic activity against a hormone-insensitive model of prostate cancer. Anticancer Drugs 2012;23:543-52.
-
(2012)
Anticancer Drugs
, vol.23
, pp. 543-552
-
-
Musende, A.G.1
Eberding, A.2
Wood, C.A.3
Adomat, H.4
Fazli, L.5
HurtadoColl, A.6
Jia, W.7
Bally, M.B.8
Guns, E.S.T.9
-
63
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
Newman DJ, Cragg GM. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod 2012;75:311-35.
-
(2012)
J Nat Prod
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
65
-
-
79961179947
-
Synergies between synthetic biology and metabolic engineering
-
Nielsen J, Keasling JD. Synergies between synthetic biology and metabolic engineering. Nat Biotechnol 2011;29:693-5.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 693-695
-
-
Nielsen, J.1
Keasling, J.D.2
-
66
-
-
84876784070
-
High-level semi-synthetic production of the potent antimalarial artemisinin
-
Paddon CJ, Westfall PJ, Pitera DJ, et al. High-level semi-synthetic production of the potent antimalarial artemisinin. Nature 2013;496:528-32.
-
(2013)
Nature
, vol.496
, pp. 528-532
-
-
Paddon, C.J.1
Westfall, P.J.2
Pitera, D.J.3
-
67
-
-
0036138566
-
Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture
-
Papanikolaou S, Aggelis G. Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture. Bioresour Technol 2002;82:43-9.
-
(2002)
Bioresour Technol
, vol.82
, pp. 43-49
-
-
Papanikolaou, S.1
Aggelis, G.2
-
69
-
-
0029776005
-
Yeast expression of animal and plant P450s in optimized redox environments
-
Pompon D, Louerat B, Bronine A, Urban P. Yeast expression of animal and plant P450s in optimized redox environments. Methods Enzymol 1996;272:51-64.
-
(1996)
Methods Enzymol
, vol.272
, pp. 51-64
-
-
Pompon, D.1
Louerat, B.2
Bronine, A.3
Urban, P.4
-
70
-
-
84888771270
-
Improving carotenoids production in yeast via adaptive laboratory evolution
-
Reyes LH, Gomez JM, Kao KC. Improving carotenoids production in yeast via adaptive laboratory evolution. Metab Eng 2014;21:26-33.
-
(2014)
Metab Eng
, vol.21
, pp. 26-33
-
-
Reyes, L.H.1
Gomez, J.M.2
Kao, K.C.3
-
71
-
-
33645870422
-
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
-
Ro DK, Paradise EM, Ouellet M, et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 2006;440:940-3.
-
(2006)
Nature
, vol.440
, pp. 940-943
-
-
Ro, D.K.1
Paradise, E.M.2
Ouellet, M.3
-
72
-
-
52949093520
-
Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin
-
Seki H, Ohyama K, Sawai S, Mizutani M, Ohnishi T, Sudo H, Akashi T, Aoki T, Saito K, Muranaka T. Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin. P Natl Acad Sci USA 2008;105:14204-9.
-
(2008)
P Natl Acad Sci USA
, vol.105
, pp. 14204-14209
-
-
Seki, H.1
Ohyama, K.2
Sawai, S.3
Mizutani, M.4
Ohnishi, T.5
Sudo, H.6
Akashi, T.7
Aoki, T.8
Saito, K.9
Muranaka, T.10
-
73
-
-
84855180697
-
Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin
-
Seki H, Sawai S, Ohyama K, et al. Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin. Plant Cell 2011;23:4112-23.
-
(2011)
Plant Cell
, vol.23
, pp. 4112-4123
-
-
Seki, H.1
Sawai, S.2
Ohyama, K.3
-
74
-
-
59649108349
-
DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways
-
Shao Z, Zhao H. DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways. Nucleic Acids Res 2009;37:e16.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Shao, Z.1
Zhao, H.2
-
75
-
-
84857048835
-
Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools
-
Siddiqui MS, Thodey K, Trenchard I, Smolke CD. Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Res 2012;12:144-70.
-
(2012)
FEMS Yeast Res
, vol.12
, pp. 144-170
-
-
Siddiqui, M.S.1
Thodey, K.2
Trenchard, I.3
Smolke, C.D.4
-
76
-
-
84890237635
-
Recent advancements in synthetic biology: current status and challenges
-
Singh V. Recent advancements in synthetic biology: current status and challenges. Gene 2014;535:1-11.
-
(2014)
Gene
, vol.535
, pp. 1-11
-
-
Singh, V.1
-
77
-
-
80052033032
-
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance
-
Souza CM, Schwabe TM, Pichler H, Ploier B, Leitner E, Guan XL, Wenk MR, Riezman I, Riezman H. A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance. Metab Eng 2011;13:555-69.
-
(2011)
Metab Eng
, vol.13
, pp. 555-569
-
-
Souza, C.M.1
Schwabe, T.M.2
Pichler, H.3
Ploier, B.4
Leitner, E.5
Guan, X.L.6
Wenk, M.R.7
Riezman, I.8
Riezman, H.9
-
78
-
-
77952268311
-
Considerable increase in resveratrol production by recombinant industrial yeast strains with use of rich medium
-
Sydor T, Schaffer S, Boles E. Considerable increase in resveratrol production by recombinant industrial yeast strains with use of rich medium. Appl Environ Microbiol 2010;76:3361-3.
-
(2010)
Appl Environ Microbiol
, vol.76
, pp. 3361-3363
-
-
Sydor, T.1
Schaffer, S.2
Boles, E.3
-
79
-
-
0037313962
-
Total biosynthesis of hydrocortisone from a simple carbon source in yeast
-
Szczebara FM, Chandelier C, Villeret C, et al. Total biosynthesis of hydrocortisone from a simple carbon source in yeast. Nat Biotechnol 2003;21:143-9.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 143-149
-
-
Szczebara, F.M.1
Chandelier, C.2
Villeret, C.3
-
80
-
-
33748809553
-
Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng
-
Tansakul P, Shibuya M, Kushiro T, Ebizuka Y. Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng. FEBS Lett 2006;580:5143-9.
-
(2006)
FEBS Lett
, vol.580
, pp. 5143-5149
-
-
Tansakul, P.1
Shibuya, M.2
Kushiro, T.3
Ebizuka, Y.4
-
81
-
-
79953171537
-
Metabolic engineering of Saccharomyces cerevisiae for production of eicosapentaenoic acid, using a novel delta 5-desaturase from Paramecium tetraurelia
-
Tavares S, Grotkjaer T, Obsen T, Haslam RP, Napier JA, Gunnarsson N. Metabolic engineering of Saccharomyces cerevisiae for production of eicosapentaenoic acid, using a novel delta 5-desaturase from Paramecium tetraurelia. Appl Environ Microbiol 2011;77:1854-61.
-
(2011)
Appl Environ Microbiol
, vol.77
, pp. 1854-1861
-
-
Tavares, S.1
Grotkjaer, T.2
Obsen, T.3
Haslam, R.P.4
Napier, J.A.5
Gunnarsson, N.6
-
82
-
-
68149089486
-
Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annua
-
Teoh KH, Polichuk DR, Reed DW, Covello PS. Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annua. Botany 2009;87:635-42.
-
(2009)
Botany
, vol.87
, pp. 635-642
-
-
Teoh, K.H.1
Polichuk, D.R.2
Reed, D.W.3
Covello, P.S.4
-
83
-
-
70449533072
-
Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae
-
Trantas E, Panopoulos N, Ververidis F. Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae. Metab Eng 2009;11:355-66.
-
(2009)
Metab Eng
, vol.11
, pp. 355-366
-
-
Trantas, E.1
Panopoulos, N.2
Ververidis, F.3
-
84
-
-
70449396286
-
Metabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance
-
Ukibe K, Hashida K, Yoshida N, Takagi H. Metabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance. Appl Environ Microbiol 2009;75:7205-11.
-
(2009)
Appl Environ Microbiol
, vol.75
, pp. 7205-7211
-
-
Ukibe, K.1
Hashida, K.2
Yoshida, N.3
Takagi, H.4
-
86
-
-
79959216987
-
Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae
-
Varman AM, Xiao Y, Leonard E, Tang YJ. Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae. Microb Cell Fact 2011;10:45.
-
(2011)
Microb Cell Fact
, vol.10
, pp. 45
-
-
Varman, A.M.1
Xiao, Y.2
Leonard, E.3
Tang, Y.J.4
-
87
-
-
34447543117
-
High-level production of betacarotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous
-
Verwaal R, Wang J, Meijnen JP, Visser H, Sandmann G, van den Berg JA, van Ooyen AJ. High-level production of betacarotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous. Appl Environ Microbiol 2007;73:4342-50.
-
(2007)
Appl Environ Microbiol
, vol.73
, pp. 4342-4350
-
-
Verwaal, R.1
Wang, J.2
Meijnen, J.P.3
Visser, H.4
Sandmann, G.5
van den Berg, J.A.6
van Ooyen, A.J.7
-
88
-
-
0345118986
-
Metabolic engineering of the astaxanthin-biosynthetic pathway of Xanthophyllomyces dendrorhous
-
Visser H, van Ooyen AJJ, Verdoes JC. Metabolic engineering of the astaxanthin-biosynthetic pathway of Xanthophyllomyces dendrorhous. FEMS Yeast Res 2003;4:221-31.
-
(2003)
FEMS Yeast Res
, vol.4
, pp. 221-231
-
-
Visser, H.1
van Ooyen, A.J.J.2
Verdoes, J.C.3
-
89
-
-
50249105159
-
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply
-
Wattanachaisaereekul S, Lantz AE, Nielsen ML, Nielsen J. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. Metab Eng 2008;10:246-54.
-
(2008)
Metab Eng
, vol.10
, pp. 246-254
-
-
Wattanachaisaereekul, S.1
Lantz, A.E.2
Nielsen, M.L.3
Nielsen, J.4
-
90
-
-
84856389651
-
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
-
Westfall PJ, Pitera DJ, Lenihan JR, et al. Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. P Natl Acad Sci USA 2012;109:E111-8.
-
(2012)
P Natl Acad Sci USA
, vol.109
, pp. E111-E118
-
-
Westfall, P.J.1
Pitera, D.J.2
Lenihan, J.R.3
-
91
-
-
84890893327
-
Astaxanthin alleviates brain aging in rats by attenuating oxidative stress and increasing BDNF levels
-
Wu WQ, Wang X, Xiang QS, Meng X, Peng Y, Du N, Liu ZG, Sun QC, Wang C, Liu XB. Astaxanthin alleviates brain aging in rats by attenuating oxidative stress and increasing BDNF levels. Food Funct 2014;5:158-66.
-
(2014)
Food Funct
, vol.5
, pp. 158-166
-
-
Wu, W.Q.1
Wang, X.2
Xiang, Q.S.3
Meng, X.4
Peng, Y.5
Du, N.6
Liu, Z.G.7
Sun, Q.C.8
Wang, C.9
Liu, X.B.10
-
93
-
-
84883785746
-
Taking the fish out of fish oil
-
Wynn JP. Taking the fish out of fish oil. Nat Biotechnol 2013;31:716-7.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 716-717
-
-
Wynn, J.P.1
-
94
-
-
84879541446
-
Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest
-
Xiao M, Zhang Y, Chen X, et al. Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. J Biotechnol 2013;166:122-34.
-
(2013)
J Biotechnol
, vol.166
, pp. 122-134
-
-
Xiao, M.1
Zhang, Y.2
Chen, X.3
-
95
-
-
0023681436
-
Biosynthesis of cholesterol in the yeast mutant Erg6
-
Xu SH, Nes WD. Biosynthesis of cholesterol in the yeast mutant Erg6. Biochem Biophys Res Commun 1988;155:509-17.
-
(1988)
Biochem Biophys Res Commun
, vol.155
, pp. 509-517
-
-
Xu, S.H.1
Nes, W.D.2
-
96
-
-
84883802093
-
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
-
Xue Z, Sharpe PL, Hong SP, et al. Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica. Nat Biotechnol 2013;31:734-40.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 734-740
-
-
Xue, Z.1
Sharpe, P.L.2
Hong, S.P.3
-
97
-
-
85007940083
-
Metabolic engineering for production of beta-carotene and lycopene in Saccharomyces cerevisiae
-
Yamano S, Ishii T, Nakagawa M, Ikenaga H, Misawa N. Metabolic engineering for production of beta-carotene and lycopene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 1994;58:1112-4.
-
(1994)
Biosci Biotechnol Biochem
, vol.58
, pp. 1112-1114
-
-
Yamano, S.1
Ishii, T.2
Nakagawa, M.3
Ikenaga, H.4
Misawa, N.5
-
98
-
-
25144431998
-
Biosynthesis of natural flavanones in Saccharomyces cerevisiae
-
Yan Y, Kohli A, Koffas MA. Biosynthesis of natural flavanones in Saccharomyces cerevisiae. Appl Environ Microbiol 2005;71:5610-3.
-
(2005)
Appl Environ Microbiol
, vol.71
, pp. 5610-5613
-
-
Yan, Y.1
Kohli, A.2
Koffas, M.A.3
-
99
-
-
84901857149
-
Production of bioactive ginsenoside compound K in metabolically engineered yeast
-
Yan X, Fan Y, Wei W, Wang P, Liu Q, Wei Y, Zhang L, Zhao G, Yue J, Zhou Z. Production of bioactive ginsenoside compound K in metabolically engineered yeast. Cell Res 2014;24: 770-3.
-
(2014)
Cell Res
, vol.24
, pp. 770-773
-
-
Yan, X.1
Fan, Y.2
Wei, W.3
Wang, P.4
Liu, Q.5
Wei, Y.6
Zhang, L.7
Zhao, G.8
Yue, J.9
Zhou, Z.10
-
100
-
-
84855598579
-
Metabolic engineering for the production of clinically important molecules: omega-3 fatty acids, artemisinin, and taxol
-
Ye VM, Bhatia SK. Metabolic engineering for the production of clinically important molecules: omega-3 fatty acids, artemisinin, and taxol. Biotechnol J 2012;7:20-33.
-
(2012)
Biotechnol J
, vol.7
, pp. 20-33
-
-
Ye, V.M.1
Bhatia, S.K.2
-
101
-
-
77955428907
-
Production of plant bioactive triterpenoid saponins: elicitation strategies and target genes to improve yields
-
Yendo AC, de Costa F, Gosmann G, Fett-Neto AG. Production of plant bioactive triterpenoid saponins: elicitation strategies and target genes to improve yields. Mol Biotechnol 2010;46:94-104.
-
(2010)
Mol Biotechnol
, vol.46
, pp. 94-104
-
-
Yendo, A.C.1
de Costa, F.2
Gosmann, G.3
Fett-Neto, A.G.4
-
102
-
-
84873322358
-
Functional identification of valerena-1,10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in Valeriana officinalis
-
Yeo YS, Nybo SE, Chittiboyina AG, et al. Functional identification of valerena-1,10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in Valeriana officinalis. J Biol Chem 2013;288:3163-73.
-
(2013)
J Biol Chem
, vol.288
, pp. 3163-3173
-
-
Yeo, Y.S.1
Nybo, S.E.2
Chittiboyina, A.G.3
-
103
-
-
84878126594
-
Engineered production of fungal anticancer cyclooligomer depsipeptides in Saccharomyces cerevisiae
-
Yu D, Xu F, Zi J, Wang S, Gage D, Zeng J, Zhan J. Engineered production of fungal anticancer cyclooligomer depsipeptides in Saccharomyces cerevisiae. Metab Eng 2013;18:60-8.
-
(2013)
Metab Eng
, vol.18
, pp. 60-68
-
-
Yu, D.1
Xu, F.2
Zi, J.3
Wang, S.4
Gage, D.5
Zeng, J.6
Zhan, J.7
-
104
-
-
33749508478
-
Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and mammalian cells
-
Zhang YS, Li SZ, Li J, Pan XQ, Cahoon RE, Jaworski JG, Wang XM, Jez JM, Chen F, Yu O. Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and mammalian cells. J Am Chem Soc 2006;128:13030-1.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 13030-13031
-
-
Zhang, Y.S.1
Li, S.Z.2
Li, J.3
Pan, X.Q.4
Cahoon, R.E.5
Jaworski, J.G.6
Wang, X.M.7
Jez, J.M.8
Chen, F.9
Yu, O.10
-
105
-
-
27844511101
-
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
-
Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 2005;45:1345-59.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.3
-
106
-
-
84863116515
-
Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production
-
Zhou YJ, Gao W, Rong Q, et al. Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production. J Am Chem Soc 2012;134: 3234-41.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 3234-3241
-
-
Zhou, Y.J.1
Gao, W.2
Rong, Q.3
-
107
-
-
84883618380
-
Novel fermentation processes for manufacturing plant natural products
-
Zhou JW, Du GC, Chen J. Novel fermentation processes for manufacturing plant natural products. Curr Opin Biotechnol 2014;25:17-23.
-
(2014)
Curr Opin Biotechnol
, vol.25
, pp. 17-23
-
-
Zhou, J.W.1
Du, G.C.2
Chen, J.3
|