Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis

Phytochemistry

Volumn 52, Issue 5, 1999, Pages 843-854

  Bouwmeester, Harro J ^a   Wallaart, T Eelco ^b   Janssen, Michiel H A ^a   Van Loo, Bert ^a   Jansen, Ben J M ^a   Posthumus, Maarten A ^a   Schmidt, Claus O ^c   De Kraker, Jan Willem ^a   König, Wilfried A ^c   Franssen, Maurice C R ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Amorpha 4,11 diene; Artemisia annua; Artemisinin; Asteraceae; Biosynthesis; Sesquiterpenoids

Indexed keywords

ALKADIENE; AMORPHA-4,11-DIENE SYNTHASE; ANTIMALARIAL AGENT; ARTEMISIA; ARTEMISINIC ACID; ARTEMISININ; CHINESE HERB; FARNESYL DIPHOSPHATE; ISOPRENOID PHOSPHATE; LIGASE; SESQUITERPENE; SESQUITERPENE DERIVATIVE; SYNTHETASE; TRANSFERASE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYMOLOGY; MALARIA; METABOLISM; MOLECULAR WEIGHT; NONHUMAN; PH; PLANT LEAF;

ALKYL AND ARYL TRANSFERASES; ANTIMALARIALS; ARTEMISIA; ARTEMISININS; CATALYSIS; DRUGS, CHINESE HERBAL; HYDROGEN-ION CONCENTRATION; LIGASES; MOLECULAR WEIGHT; PLANT LEAVES; PLANTS, MEDICINAL; POLYISOPRENYL PHOSPHATES; SESQUITERPENES;

AMORPHA; ARTEMISIA ANNUA; ASTERACEAE; PROTOZOA;

EID: 0033230281     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(99)00206-X     Document Type: Article

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