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Volumn 98, Issue 1, 2014, Pages 345-350

Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant

Author keywords

Astaxanthin; Carotenoid pathway; Pathway engineering; Xanthophyllomyces dendrorhous

Indexed keywords

GENETIC ENGINEERING; METABOLITES;

EID: 84891857645     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5358-z     Document Type: Article
Times cited : (78)

References (24)
  • 1
    • 0000180004 scopus 로고
    • (3R,3′R)-Astaxanthin from the yeast Phaffia rhodozyma
    • 1:CAS:528:DyaE28XltVyrs7Y%3D 10.1016/S0031-9422(00)84391-5
    • Andrewes AG, Starr MP (1976) (3R,3′R)-Astaxanthin from the yeast Phaffia rhodozyma. Phytochem 15:1009-1011
    • (1976) Phytochem , vol.15 , pp. 1009-1011
    • Andrewes, A.G.1    Starr, M.P.2
  • 2
    • 0030996054 scopus 로고    scopus 로고
    • XcmI-containing vector for direct cloning of PCR products
    • 1:CAS:528:DyaK2sXjtFWqt74%3D
    • Borovkov AY, Rivkin MI (1997) XcmI-containing vector for direct cloning of PCR products. BioTechn 22:812-814
    • (1997) BioTechn , vol.22 , pp. 812-814
    • Borovkov, A.Y.1    Rivkin, M.I.2
  • 3
    • 79952763038 scopus 로고    scopus 로고
    • Engineering of geranylgeranyl pyrophosphate synthase levels and physiological conditions for enhanced carotenoid and astaxanthin synthesis in Xanthophyllomyces dendrorhous
    • 1:CAS:528:DC%2BC3MXjsFemsbk%3D 21165672 10.1007/s10529-010-0495-2
    • Breitenbach J, Visser H, Verdoes JC, van Ooyen AJ, Sandmann G (2011) Engineering of geranylgeranyl pyrophosphate synthase levels and physiological conditions for enhanced carotenoid and astaxanthin synthesis in Xanthophyllomyces dendrorhous. Biotechnol Lett 33:755-761
    • (2011) Biotechnol Lett , vol.33 , pp. 755-761
    • Breitenbach, J.1    Visser, H.2    Verdoes, J.C.3    Van Ooyen, A.J.4    Sandmann, G.5
  • 5
    • 84874811921 scopus 로고    scopus 로고
    • Multiple improvement of astaxanthin biosynthesis in Xanthophyllomyces dendrorhous by a combination of conventional mutagenesis and metabolic pathway engineering
    • 1:CAS:528:DC%2BC3sXjslejurY%3D 23187756 10.1007/s10529-012-1103-4
    • Gassel S, Schewe H, Schmidt I, Schrader J, Sandmann G (2013) Multiple improvement of astaxanthin biosynthesis in Xanthophyllomyces dendrorhous by a combination of conventional mutagenesis and metabolic pathway engineering. Biotechnol Lett 35:565-569
    • (2013) Biotechnol Lett , vol.35 , pp. 565-569
    • Gassel, S.1    Schewe, H.2    Schmidt, I.3    Schrader, J.4    Sandmann, G.5
  • 6
    • 0021078994 scopus 로고
    • Plasmid-encoded hygromycin B resistance: The sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae
    • 1:CAS:528:DyaL2cXpslChtA%3D%3D 6319235 10.1016/0378-1119(83)90223-8
    • Gritz L, Davies J (1983) Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene 25:179-188
    • (1983) Gene , vol.25 , pp. 179-188
    • Gritz, L.1    Davies, J.2
  • 7
    • 0021743146 scopus 로고
    • Construction of a family of universal expression plasmid vectors
    • 10.1016/0378-1119(84)90128-8
    • Hanna Z, Fregeau C, Préfontaine G, Brousseau R (1984) Construction of a family of universal expression plasmid vectors. Gene 247:247-250
    • (1984) Gene , vol.247 , pp. 247-250
    • Hanna, Z.1    Fregeau, C.2    Préfontaine, G.3    Brousseau, R.4
  • 9
    • 0023857885 scopus 로고
    • Analysis of the nourseothricin-resistance gene (nat) of Streptomyces noursei
    • 2835292 10.1016/0378-1119(88)90559-8
    • Krügel H, Fiedler G, Haupt I, Sarfert E, Simon H (1988) Analysis of the nourseothricin-resistance gene (nat) of Streptomyces noursei. Gene 62:209-217
    • (1988) Gene , vol.62 , pp. 209-217
    • Krügel, H.1    Fiedler, G.2    Haupt, I.3    Sarfert, E.4    Simon, H.5
  • 10
    • 0034175978 scopus 로고    scopus 로고
    • Commercial potential for Haematococcus microalgae as a natural source of astaxanthin
    • 1:CAS:528:DC%2BD3cXit1SqsLo%3D 10740262 10.1016/S0167-7799(00)01433-5
    • Lorenz R, Cysewski G (2000) Commercial potential for Haematococcus microalgae as a natural source of astaxanthin. Trends Biotechnol 18:160-167
    • (2000) Trends Biotechnol , vol.18 , pp. 160-167
    • Lorenz, R.1    Cysewski, G.2
  • 11
    • 0032922650 scopus 로고    scopus 로고
    • Production of ketocarotenoids by microalgae
    • 1:CAS:528:DyaK1MXjtlagtLc%3D 10341427 10.1007/s002530051413
    • Margalith PZ (1999) Production of ketocarotenoids by microalgae. Appl Microbiol Biotechnol 51:431-438
    • (1999) Appl Microbiol Biotechnol , vol.51 , pp. 431-438
    • Margalith, P.Z.1
  • 12
    • 0028817748 scopus 로고
    • Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level
    • 1:CAS:528:DyaK2MXptlKrt78%3D 177511 7592436
    • Misawa N, Satomi Y, Kondo K, Yokoyama A, Kajiwara S, Saito T, Ohtani T, Miki W (1995) Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level. J Bacteriol 177:6575-6584
    • (1995) J Bacteriol , vol.177 , pp. 6575-6584
    • Misawa, N.1    Satomi, Y.2    Kondo, K.3    Yokoyama, A.4    Kajiwara, S.5    Saito, T.6    Ohtani, T.7    Miki, W.8
  • 13
    • 32444444375 scopus 로고    scopus 로고
    • Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a beta- carotene 3-hydroxylase/4-ketolase
    • 1:CAS:528:DC%2BD28XhtlSqtbY%3D 16416328 10.1007/s00438-005-0072-x
    • Ojima K, Breitenbach J, Visser H, Setoguchi Y, Tabata K, Hoshino T, van den Berg J, Sandmann G (2006) Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a beta- carotene 3-hydroxylase/4-ketolase. Mol Genet Genomics 275:148-158
    • (2006) Mol Genet Genomics , vol.275 , pp. 148-158
    • Ojima, K.1    Breitenbach, J.2    Visser, H.3    Setoguchi, Y.4    Tabata, K.5    Hoshino, T.6    Van Den Berg, J.7    Sandmann, G.8
  • 14
    • 78149359483 scopus 로고    scopus 로고
    • Xanthophyllomyces dendrorhous for the industrial production of astaxanthin
    • 1:CAS:528:DC%2BC3cXhtFGhtLjF 20711573 10.1007/s00253-010-2814-x
    • Rodriguez-Saiz M, de la Fuente JL, Barredo JL (2010) Xanthophyllomyces dendrorhous for the industrial production of astaxanthin. Appl Microbiol Biotechnol 88:645-658
    • (2010) Appl Microbiol Biotechnol , vol.88 , pp. 645-658
    • Rodriguez-Saiz, M.1    De La Fuente, J.L.2    Barredo, J.L.3
  • 15
    • 0036901989 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of carotenoids in a heterologous host: A powerful approach for the biosynthesis of novel structures
    • 1:CAS:528:DC%2BD38Xlt1Kmtbo%3D
    • Sandmann G (2002) Combinatorial biosynthesis of carotenoids in a heterologous host: a powerful approach for the biosynthesis of novel structures. Chem BioChem 3:629-635
    • (2002) Chem BioChem , vol.3 , pp. 629-635
    • Sandmann, G.1
  • 17
    • 13844262178 scopus 로고
    • Occurrence of astaxanthin in the flower petals of Adonis annua L
    • 1:CAS:528:DyaF3cXmvFSntA%3D%3D 14445279 10.1038/1841714a0
    • Seybold A, Goodwin TW (1959) Occurrence of astaxanthin in the flower petals of Adonis annua L. Nature 184:1714-1715
    • (1959) Nature , vol.184 , pp. 1714-1715
    • Seybold, A.1    Goodwin, T.W.2
  • 18
    • 0031843028 scopus 로고    scopus 로고
    • Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway
    • 1:CAS:528:DyaK1cXkt1Ogs7g%3D 106443 9647847
    • Shimada H, Kondo K, Fraser PD, Miura Y, Saito T, Misawa N (1998) Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway. Appl Environ Microbiol 64:2676-2680
    • (1998) Appl Environ Microbiol , vol.64 , pp. 2676-2680
    • Shimada, H.1    Kondo, K.2    Fraser, P.D.3    Miura, Y.4    Saito, T.5    Misawa, N.6
  • 19
    • 0032722810 scopus 로고    scopus 로고
    • Isolation and functional characterisation of a novel type of carotenoid biosynthetic gene from Xanthophyllomyces dendrorhous
    • 1:CAS:528:DyaK1MXnvFKrsbg%3D 10589832 10.1007/s004380051105
    • Verdoes JC, Krubasik KP, Sandmann G, van Ooyen AJ (1999a) Isolation and functional characterisation of a novel type of carotenoid biosynthetic gene from Xanthophyllomyces dendrorhous. Mol Gen Genet 262:453-461
    • (1999) Mol Gen Genet , vol.262 , pp. 453-461
    • Verdoes, J.C.1    Krubasik, K.P.2    Sandmann, G.3    Van Ooyen, A.J.4
  • 20
    • 0033587374 scopus 로고    scopus 로고
    • Cloning and characterization of the astaxanthin biosynthetic gene encoding phytoene desaturase of Xanthophyllomyces dendrorhous
    • 1:CAS:528:DyaK1MXis12js74%3D 10397832 10.1002/(SICI)1097-0290(19990620) 63:6<750: AID-BIT13>3.0.CO;2-7
    • Verdoes JC, Misawa N, van Ooyen AJJ (1999b) Cloning and characterization of the astaxanthin biosynthetic gene encoding phytoene desaturase of Xanthophyllomyces dendrorhous. Biotechnol Bioeng 63:750-755
    • (1999) Biotechnol Bioeng , vol.63 , pp. 750-755
    • Verdoes, J.C.1    Misawa, N.2    Van Ooyen, A.J.J.3
  • 21
    • 0037479864 scopus 로고    scopus 로고
    • Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma)
    • 1:CAS:528:DC%2BD3sXlsFagsbo%3D 165150 12839738 10.1128/AEM.69.7.3728- 3738.2003
    • Verdoes JC, Sandmann G, Visser H, Diaz M, van Mossel M, van Ooyen AJ (2003) Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma). Appl Environ Microbiol 69:3728-3738
    • (2003) Appl Environ Microbiol , vol.69 , pp. 3728-3738
    • Verdoes, J.C.1    Sandmann, G.2    Visser, H.3    Diaz, M.4    Van Mossel, M.5    Van Ooyen, A.J.6
  • 22
    • 34447543117 scopus 로고    scopus 로고
    • High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous
    • 1:CAS:528:DC%2BD2sXot1OrtrY%3D 1932764 17496128 10.1128/AEM.02759-06
    • Verwaal R, Wang J, Meijnen J, Visser H, Sandmann G, van den Berg JA, van Ooyen AJJ (2007) High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous. Appl Environ Microbiol 73:4342-4350
    • (2007) Appl Environ Microbiol , vol.73 , pp. 4342-4350
    • Verwaal, R.1    Wang, J.2    Meijnen, J.3    Visser, H.4    Sandmann, G.5    Van Den Berg, J.A.6    Van Ooyen, A.J.J.7
  • 23
    • 32444435890 scopus 로고    scopus 로고
    • Xanthophylls in fungi: Metabolic engineering of the astaxanthin biosynthetic pathway in Xanthophyllomyces dendrorhous
    • Totowa, NJ, USA
    • Visser H, Sandmann G, Verdoes JC (2005) Xanthophylls in fungi: Metabolic engineering of the astaxanthin biosynthetic pathway in Xanthophyllomyces dendrorhous. Methods in Biotechnology. Microbiol Processes and Products, Totowa, NJ, USA
    • (2005) Methods in Biotechnology. Microbiol Processes and Products
    • Visser, H.1    Sandmann, G.2    Verdoes, J.C.3
  • 24
    • 0031811761 scopus 로고    scopus 로고
    • Efficient transformation of the astaxanthin-producing yeast Phaffia rhodozyma
    • 1:CAS:528:DyaK1cXkt1OjtL4%3D 10.1023/A:1008834600770
    • Wery J, Verdoes JC, Van Ooyen AJ (1998) Efficient transformation of the astaxanthin-producing yeast Phaffia rhodozyma. Biotechnol Tech 12:399-405
    • (1998) Biotechnol Tech , vol.12 , pp. 399-405
    • Wery, J.1    Verdoes, J.C.2    Van Ooyen, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.