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Volumn 46, Issue , 2017, Pages 215-226

Designing food structure and composition to enhance nutraceutical bioactivity to support cancer inhibition

Author keywords

Bioavailability; Cancer; Delivery systems; Excipients; Nutraceuticals

Indexed keywords

CURCUMIN; EXCIPIENT; FLAVONOID; LIPOSOME; NUTRACEUTICAL; POLYPHENOL; QUERCETIN; RESVERATROL; SOLID LIPID NANOPARTICLE; SULFORAPHANE; TANGERETIN; ANTINEOPLASTIC AGENT;

EID: 85020407041     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2017.06.003     Document Type: Review
Times cited : (67)

References (129)
  • 1
    • 84967309078 scopus 로고    scopus 로고
    • Nutraceuticals: Efficacy, Safety and Toxicity
    • Academic Press London, U.K
    • Gupta, R.C., Nutraceuticals: Efficacy, Safety and Toxicity. 2016, Academic Press, London, U.K.
    • (2016)
    • Gupta, R.C.1
  • 2
    • 62549138104 scopus 로고    scopus 로고
    • Nutraceuticals and functional foods
    • R.E.C. Wildman 2nd ed. CRC Press Boco Raton, FL
    • Wildman, R.E.C., Kelley, M., Nutraceuticals and functional foods. Wildman, R.E.C., (eds.) Handbook of Nutraceuticals and Functional Foods, 2nd ed., 2007, CRC Press, Boco Raton, FL, 1–22.
    • (2007) Handbook of Nutraceuticals and Functional Foods , pp. 1-22
    • Wildman, R.E.C.1    Kelley, M.2
  • 3
    • 84942673790 scopus 로고    scopus 로고
    • Nutraceuticals and Functional Foods in Human Health and Disease Prevention
    • CRC Press Boca Raton, FL
    • Bagchi, D., Preuss, H.G., Sarwoop, A., Nutraceuticals and Functional Foods in Human Health and Disease Prevention. 2015, CRC Press, Boca Raton, FL.
    • (2015)
    • Bagchi, D.1    Preuss, H.G.2    Sarwoop, A.3
  • 4
    • 84907632749 scopus 로고    scopus 로고
    • Nanoparticle- and Microparticle-based Delivery Systems
    • CRC Press Boca Raton, FL
    • McClements, D.J., Nanoparticle- and Microparticle-based Delivery Systems. 2015, CRC Press, Boca Raton, FL.
    • (2015)
    • McClements, D.J.1
  • 5
    • 84969847933 scopus 로고    scopus 로고
    • Oral delivery strategies for nutraceuticals: delivery vehicles and absorption enhancers
    • Gleeson, J.P., Ryan, S.M., Brayden, D.J., Oral delivery strategies for nutraceuticals: delivery vehicles and absorption enhancers. Trends Food Sci. Technol. 53 (2016), 90–101.
    • (2016) Trends Food Sci. Technol. , vol.53 , pp. 90-101
    • Gleeson, J.P.1    Ryan, S.M.2    Brayden, D.J.3
  • 6
    • 84926462020 scopus 로고    scopus 로고
    • Enhancing nutraceutical bioavailability through food matrix design
    • McClements, D.J., Enhancing nutraceutical bioavailability through food matrix design. Curr. Opin. Food Sci. 4 (2015), 1–6.
    • (2015) Curr. Opin. Food Sci. , vol.4 , pp. 1-6
    • McClements, D.J.1
  • 7
    • 84926508869 scopus 로고    scopus 로고
    • The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability
    • McClements, D.J., Li, F., Xiao, H., The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability. Ann. Rev. Food Sci. Technol. 6 (2015), 299–327.
    • (2015) Ann. Rev. Food Sci. Technol. , vol.6 , pp. 299-327
    • McClements, D.J.1    Li, F.2    Xiao, H.3
  • 9
    • 84974555444 scopus 로고    scopus 로고
    • Nanocarriers based delivery of nutraceuticals for cancer prevention and treatment: a review of recent research developments
    • Arora, D., Jaglan, S., Nanocarriers based delivery of nutraceuticals for cancer prevention and treatment: a review of recent research developments. Trends Food Sci. Technol. 54 (2016), 114–126.
    • (2016) Trends Food Sci. Technol. , vol.54 , pp. 114-126
    • Arora, D.1    Jaglan, S.2
  • 10
    • 35348900910 scopus 로고    scopus 로고
    • Emulsion-based delivery systems for lipophilioc bioactive components
    • McClements, D.J., Decker, E.A., Weiss, J., Emulsion-based delivery systems for lipophilioc bioactive components. J. Food Sci. 72:8 (2007), R109–R124.
    • (2007) J. Food Sci. , vol.72 , Issue.8 , pp. R109-R124
    • McClements, D.J.1    Decker, E.A.2    Weiss, J.3
  • 12
    • 84890893432 scopus 로고    scopus 로고
    • Influence of particle size on lipid digestion and beta-carotene bioaccessibility in emulsions and nanoemulsions
    • Salvia-Trujillo, L., Qian, C., Martin-Belloso, O., McClements, D.J., Influence of particle size on lipid digestion and beta-carotene bioaccessibility in emulsions and nanoemulsions. Food Chem. 141:2 (2013), 1472–1480.
    • (2013) Food Chem. , vol.141 , Issue.2 , pp. 1472-1480
    • Salvia-Trujillo, L.1    Qian, C.2    Martin-Belloso, O.3    McClements, D.J.4
  • 13
    • 84903311446 scopus 로고    scopus 로고
    • Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals
    • McClements, D.J., Xiao, H., Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals. Food Function 5:7 (2014), 1320–1333.
    • (2014) Food Function , vol.5 , Issue.7 , pp. 1320-1333
    • McClements, D.J.1    Xiao, H.2
  • 14
    • 84957429272 scopus 로고    scopus 로고
    • Impact of lipid content on the ability of excipient emulsions to increase carotenoid bioaccessibility from natural sources (raw and cooked carrots)
    • Zhang, R.J., Zhang, Z.P., Zou, L.Q., Xiao, H., Zhang, G.D., Decker, E.A., McClements, D.J., Impact of lipid content on the ability of excipient emulsions to increase carotenoid bioaccessibility from natural sources (raw and cooked carrots). Food Biophys. 11:1 (2016), 71–80.
    • (2016) Food Biophys. , vol.11 , Issue.1 , pp. 71-80
    • Zhang, R.J.1    Zhang, Z.P.2    Zou, L.Q.3    Xiao, H.4    Zhang, G.D.5    Decker, E.A.6    McClements, D.J.7
  • 15
    • 27244460098 scopus 로고    scopus 로고
    • Functional foods: a survey of health claims, pros and cons, and current legislation
    • Arvanitoyannis, I.S., van Houwelingen-Koukaliaroglou, M., Functional foods: a survey of health claims, pros and cons, and current legislation. Crit. Rev. Food Sci. Nutr. 45:5 (2005), 385–404.
    • (2005) Crit. Rev. Food Sci. Nutr. , vol.45 , Issue.5 , pp. 385-404
    • Arvanitoyannis, I.S.1    van Houwelingen-Koukaliaroglou, M.2
  • 16
    • 56749112002 scopus 로고    scopus 로고
    • Food as medicine: potential therapeutic tendencies of plant derived polyphenolic compounds
    • Ullah, M.F., Khan, M.W., Food as medicine: potential therapeutic tendencies of plant derived polyphenolic compounds. Asian Pac. J. Cancer Prev. 9:2 (2008), 187–195.
    • (2008) Asian Pac. J. Cancer Prev. , vol.9 , Issue.2 , pp. 187-195
    • Ullah, M.F.1    Khan, M.W.2
  • 17
    • 84977657836 scopus 로고    scopus 로고
    • Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence
    • Kotecha, R., Takami, A., Espinoza, J.L., Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence. Oncotarget 7:32 (2016), 52517–52529.
    • (2016) Oncotarget , vol.7 , Issue.32 , pp. 52517-52529
    • Kotecha, R.1    Takami, A.2    Espinoza, J.L.3
  • 18
    • 54449085540 scopus 로고    scopus 로고
    • Chemopreventive effects of natural dietary compounds on cancer development
    • Pan, M.H., Ho, C.T., Chemopreventive effects of natural dietary compounds on cancer development. Chem. Soc. Rev. 37:11 (2008), 2558–2574.
    • (2008) Chem. Soc. Rev. , vol.37 , Issue.11 , pp. 2558-2574
    • Pan, M.H.1    Ho, C.T.2
  • 19
    • 2142784187 scopus 로고    scopus 로고
    • Biological properties of curcumin-cellular and molecular mechanisms of action
    • Joe, B., Vijaykumar, M., Lokesh, B.R., Biological properties of curcumin-cellular and molecular mechanisms of action. Crit. Rev. Food Sci. Nutr. 44:2 (2004), 97–111.
    • (2004) Crit. Rev. Food Sci. Nutr. , vol.44 , Issue.2 , pp. 97-111
    • Joe, B.1    Vijaykumar, M.2    Lokesh, B.R.3
  • 21
    • 77149179813 scopus 로고    scopus 로고
    • Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications
    • Bar-Sela, G., Epelbaum, R., Schaffer, M., Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications. Curr. Med. Chem. 17:3 (2010), 190–197.
    • (2010) Curr. Med. Chem. , vol.17 , Issue.3 , pp. 190-197
    • Bar-Sela, G.1    Epelbaum, R.2    Schaffer, M.3
  • 22
    • 84870724084 scopus 로고    scopus 로고
    • Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia (vol. 4, pg 354, 2011)
    • 1407–1407
    • Carroll, R.E., Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia (vol. 4, pg 354, 2011). Cancer Prev. Res., 5(12), 2012 1407–1407.
    • (2012) Cancer Prev. Res. , vol.5 , Issue.12
    • Carroll, R.E.1
  • 23
    • 84898053516 scopus 로고    scopus 로고
    • Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals
    • Ting, Y.W., Jiang, Y., Ho, C.T., Huang, Q.R., Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals. J. Funct. Foods 7 (2014), 112–128.
    • (2014) J. Funct. Foods , vol.7 , pp. 112-128
    • Ting, Y.W.1    Jiang, Y.2    Ho, C.T.3    Huang, Q.R.4
  • 24
    • 84856077097 scopus 로고    scopus 로고
    • Nanocapsulated curcumin: oral chemopreventive formulation against diethylnitrosamine induced hepatocellular carcinoma in rat
    • Ghosh, D., Choudhury, S.T., Ghosh, S., Mandal, A.K., Sarkar, S., Ghosh, A., Saha, K.D., Das, N., Nanocapsulated curcumin: oral chemopreventive formulation against diethylnitrosamine induced hepatocellular carcinoma in rat. Chem. Biol. Interact. 195:3 (2012), 206–214.
    • (2012) Chem. Biol. Interact. , vol.195 , Issue.3 , pp. 206-214
    • Ghosh, D.1    Choudhury, S.T.2    Ghosh, S.3    Mandal, A.K.4    Sarkar, S.5    Ghosh, A.6    Saha, K.D.7    Das, N.8
  • 25
    • 84897584012 scopus 로고    scopus 로고
    • The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes
    • Schiborr, C., Kocher, A., Behnam, D., Jandasek, J., Toelstede, S., Frank, J., The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes. Mol. Nutr. Food Res. 58:3 (2014), 516–527.
    • (2014) Mol. Nutr. Food Res. , vol.58 , Issue.3 , pp. 516-527
    • Schiborr, C.1    Kocher, A.2    Behnam, D.3    Jandasek, J.4    Toelstede, S.5    Frank, J.6
  • 27
    • 51349132313 scopus 로고    scopus 로고
    • Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives
    • Kundu, J.K., Surh, Y.J., Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives. Cancer Lett. 269:2 (2008), 243–261.
    • (2008) Cancer Lett. , vol.269 , Issue.2 , pp. 243-261
    • Kundu, J.K.1    Surh, Y.J.2
  • 28
    • 79961047423 scopus 로고    scopus 로고
    • Resveratrol and health – a comprehensive review of human clinical trials
    • Smoliga, J.M., Baur, J.A., Hausenblas, H.A., Resveratrol and health – a comprehensive review of human clinical trials. Mol. Nutr. Food Res. 55:8 (2011), 1129–1141.
    • (2011) Mol. Nutr. Food Res. , vol.55 , Issue.8 , pp. 1129-1141
    • Smoliga, J.M.1    Baur, J.A.2    Hausenblas, H.A.3
  • 29
    • 78751706756 scopus 로고    scopus 로고
    • Resveratrol and cellular mechanisms of cancer prevention
    • Shukla, Y., Singh, R., Resveratrol and cellular mechanisms of cancer prevention. Ann. N. Y. Acad. Sci. 1215 (2011), 1–8.
    • (2011) Ann. N. Y. Acad. Sci. , vol.1215 , pp. 1-8
    • Shukla, Y.1    Singh, R.2
  • 30
    • 79958099432 scopus 로고    scopus 로고
    • Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
    • Nguyen, A.V., Martinez, M., Stamos, M.J., Moyer, M.P., Planutis, K., Hope, C., Holcombe, R.F., Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manage. Res. 1 (2009), 25–37.
    • (2009) Cancer Manage. Res. , vol.1 , pp. 25-37
    • Nguyen, A.V.1    Martinez, M.2    Stamos, M.J.3    Moyer, M.P.4    Planutis, K.5    Hope, C.6    Holcombe, R.F.7
  • 31
    • 84859739725 scopus 로고    scopus 로고
    • Trans-resveratrol alters mammary promoter hypermethylation in women at increased risk for Breast cancer
    • Zhu, W.Z., Qin, W.Y., Zhang, K., Rottinghaus, G.E., Chen, Y.C., Kliethermes, B., Sauter, E.R., Trans-resveratrol alters mammary promoter hypermethylation in women at increased risk for Breast cancer. Nutr. Cancer 64:3 (2012), 393–400.
    • (2012) Nutr. Cancer , vol.64 , Issue.3 , pp. 393-400
    • Zhu, W.Z.1    Qin, W.Y.2    Zhang, K.3    Rottinghaus, G.E.4    Chen, Y.C.5    Kliethermes, B.6    Sauter, E.R.7
  • 32
    • 66149107051 scopus 로고    scopus 로고
    • Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
    • Narayanan, N.K., Nargi, D., Randolph, C., Narayanan, B.A., Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int. J. Cancer 125:1 (2009), 1–8.
    • (2009) Int. J. Cancer , vol.125 , Issue.1 , pp. 1-8
    • Narayanan, N.K.1    Nargi, D.2    Randolph, C.3    Narayanan, B.A.4
  • 33
    • 84861875282 scopus 로고    scopus 로고
    • Glucosinolates and isothiocyanates in health and disease
    • Dinkova-Kostova, A.T., Kostov, R.V., Glucosinolates and isothiocyanates in health and disease. Trends Mol. Med. 18:6 (2012), 337–347.
    • (2012) Trends Mol. Med. , vol.18 , Issue.6 , pp. 337-347
    • Dinkova-Kostova, A.T.1    Kostov, R.V.2
  • 34
    • 84887612717 scopus 로고    scopus 로고
    • Sulforaphane: translational research from laboratory bench to clinic
    • Houghton, C.A., Fassett, R.G., Coombes, J.S., Sulforaphane: translational research from laboratory bench to clinic. Nutr. Rev. 71:11 (2013), 709–726.
    • (2013) Nutr. Rev. , vol.71 , Issue.11 , pp. 709-726
    • Houghton, C.A.1    Fassett, R.G.2    Coombes, J.S.3
  • 35
    • 51349088974 scopus 로고    scopus 로고
    • Multi-targeted prevention of cancer by sulforaphane
    • Clarke, J.D., Dashwood, R.H., Ho, E., Multi-targeted prevention of cancer by sulforaphane. Cancer Lett. 269:2 (2008), 291–304.
    • (2008) Cancer Lett. , vol.269 , Issue.2 , pp. 291-304
    • Clarke, J.D.1    Dashwood, R.H.2    Ho, E.3
  • 36
    • 34247606510 scopus 로고    scopus 로고
    • Molecular basis for chemoprevention by sulforaphane: a comprehensive review
    • Juge, N., Mithen, R.F., Traka, M., Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell. Mol. Life Sci. 64:9 (2007), 1105–1127.
    • (2007) Cell. Mol. Life Sci. , vol.64 , Issue.9 , pp. 1105-1127
    • Juge, N.1    Mithen, R.F.2    Traka, M.3
  • 38
    • 67549138277 scopus 로고    scopus 로고
    • Dietary sulforaphane-Rich broccoli sprouts reduce colonization and attenuate gastritis in helicobacter pylori-infected mice and humans
    • Yanaka, A., Fahey, J.W., Fukumoto, A., Nakayama, M., Inoue, S., Zhang, S.H., Tauchi, M., Suzuki, H., Hyodo, I., Yamamoto, M., Dietary sulforaphane-Rich broccoli sprouts reduce colonization and attenuate gastritis in helicobacter pylori-infected mice and humans. Cancer Prev. Res. 2:4 (2009), 353–360.
    • (2009) Cancer Prev. Res. , vol.2 , Issue.4 , pp. 353-360
    • Yanaka, A.1    Fahey, J.W.2    Fukumoto, A.3    Nakayama, M.4    Inoue, S.5    Zhang, S.H.6    Tauchi, M.7    Suzuki, H.8    Hyodo, I.9    Yamamoto, M.10
  • 39
    • 74149084423 scopus 로고    scopus 로고
    • Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy
    • Do, D.P., Pai, S.B., Rizvi, S.A.A., D'Souza, M.J., Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int. J. Pharm. 386:1–2 (2010), 114–121.
    • (2010) Int. J. Pharm. , vol.386 , Issue.1-2 , pp. 114-121
    • Do, D.P.1    Pai, S.B.2    Rizvi, S.A.A.3    D'Souza, M.J.4
  • 40
    • 33747166198 scopus 로고    scopus 로고
    • Beneficial effects of green tea – a review
    • Cabrera, C., Artacho, R., Gimenez, R., Beneficial effects of green tea – a review. J. Am. Coll. Nutr. 25:2 (2006), 79–99.
    • (2006) J. Am. Coll. Nutr. , vol.25 , Issue.2 , pp. 79-99
    • Cabrera, C.1    Artacho, R.2    Gimenez, R.3
  • 41
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: chemistry, bioavailability and effects on health
    • Crozier, A., Jaganath, I.B., Clifford, M.N., Dietary phenolics: chemistry, bioavailability and effects on health. Nat. Prod. Rep. 26:8 (2009), 1001–1043.
    • (2009) Nat. Prod. Rep. , vol.26 , Issue.8 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 43
    • 84891929814 scopus 로고    scopus 로고
    • Cancer prevention by tocopherols and tea polyphenols
    • Yang, C.S., Li, G., Yang, Z., Guan, F., Chen, A., Ju, J., Cancer prevention by tocopherols and tea polyphenols. Cancer Lett. 334:1 (2013), 79–85.
    • (2013) Cancer Lett. , vol.334 , Issue.1 , pp. 79-85
    • Yang, C.S.1    Li, G.2    Yang, Z.3    Guan, F.4    Chen, A.5    Ju, J.6
  • 44
    • 85007354894 scopus 로고    scopus 로고
    • A phase ii randomized, presurgical placebo-controlled trial of polyphenon e in bladder cancer patients to evaluate bladder tissue levels of egcg and biomarkers of growth and apoptosis
    • E293–E293
    • Gee, J., Saltzstein, D., Kim, K., Kolesar, J., Huang, W., Havighurst, T., Wollmer, B., Stublaski, J., Downs, T., Mukhtar, H., House, M., Parnes, H., Bailey, H., A phase ii randomized, presurgical placebo-controlled trial of polyphenon e in bladder cancer patients to evaluate bladder tissue levels of egcg and biomarkers of growth and apoptosis. J. Urol., 193(4), 2015 E293–E293.
    • (2015) J. Urol. , vol.193 , Issue.4
    • Gee, J.1    Saltzstein, D.2    Kim, K.3    Kolesar, J.4    Huang, W.5    Havighurst, T.6    Wollmer, B.7    Stublaski, J.8    Downs, T.9    Mukhtar, H.10    House, M.11    Parnes, H.12    Bailey, H.13
  • 45
    • 33745627071 scopus 로고    scopus 로고
    • Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies
    • Sun, C.L., Yuan, J.M., Koh, W.P., Yu, M.C., Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies. Carcinogenesis 27:7 (2006), 1310–1315.
    • (2006) Carcinogenesis , vol.27 , Issue.7 , pp. 1310-1315
    • Sun, C.L.1    Yuan, J.M.2    Koh, W.P.3    Yu, M.C.4
  • 46
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I: review of 97 bioavailability studies
    • Manach, C., Williamson, G., Morand, C., Scalbert, A., Remesy, C., Bioavailability and bioefficacy of polyphenols in humans. I: review of 97 bioavailability studies. Am. J. Clin. Nutr. 81:1 (2005), 230S–242S.
    • (2005) Am. J. Clin. Nutr. , vol.81 , Issue.1 , pp. 230S-242S
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 48
    • 84862309686 scopus 로고    scopus 로고
    • Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities
    • Weng, C.J., Yen, G.C., Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. Cancer Metastasis Rev. 31:1–2 (2012), 323–351.
    • (2012) Cancer Metastasis Rev. , vol.31 , Issue.1-2 , pp. 323-351
    • Weng, C.J.1    Yen, G.C.2
  • 49
    • 84899440422 scopus 로고    scopus 로고
    • Anti-cancer potential of flavonoids: recent trends and future perspectives
    • Batra, P., Sharma, A.K., Anti-cancer potential of flavonoids: recent trends and future perspectives. 3 Biotech 3:6 (2013), 439–459.
    • (2013) 3 Biotech , vol.3 , Issue.6 , pp. 439-459
    • Batra, P.1    Sharma, A.K.2
  • 50
    • 84877812825 scopus 로고    scopus 로고
    • Quercetin in cancer prevention and therapy
    • Chirumbolo, S., Quercetin in cancer prevention and therapy. Integr. Cancer Ther. 12:2 (2013), 97–102.
    • (2013) Integr. Cancer Ther. , vol.12 , Issue.2 , pp. 97-102
    • Chirumbolo, S.1
  • 51
    • 84928905615 scopus 로고    scopus 로고
    • Quercetin in prostate cancer: chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (review)
    • Yang, F.Y., Song, L.M., Wang, H.P., Wang, J., Xu, Z.Q., Xing, N.Z., Quercetin in prostate cancer: chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (review). Oncol. Rep. 33:6 (2015), 2659–2668.
    • (2015) Oncol. Rep. , vol.33 , Issue.6 , pp. 2659-2668
    • Yang, F.Y.1    Song, L.M.2    Wang, H.P.3    Wang, J.4    Xu, Z.Q.5    Xing, N.Z.6
  • 52
    • 84955257023 scopus 로고    scopus 로고
    • Emulsion-based encapsulation and delivery systems for polyphenols
    • Lu, W., Kelly, A.L., Miao, S., Emulsion-based encapsulation and delivery systems for polyphenols. Trends Food Sci. Technol. 47 (2016), 1–9.
    • (2016) Trends Food Sci. Technol. , vol.47 , pp. 1-9
    • Lu, W.1    Kelly, A.L.2    Miao, S.3
  • 54
    • 84928989462 scopus 로고    scopus 로고
    • In vitro and in vivo anti-cancer activity of tangeretin against colorectal cancer was enhanced by emulsion-based delivery system
    • Ting, Y.W., Chiou, Y.S., Pan, M.H., Ho, C.T., Huang, Q.R., In vitro and in vivo anti-cancer activity of tangeretin against colorectal cancer was enhanced by emulsion-based delivery system. J. Funct. Foods 15 (2015), 264–273.
    • (2015) J. Funct. Foods , vol.15 , pp. 264-273
    • Ting, Y.W.1    Chiou, Y.S.2    Pan, M.H.3    Ho, C.T.4    Huang, Q.R.5
  • 55
    • 84866879823 scopus 로고    scopus 로고
    • The influence of lipophilicity in drug discovery and design
    • Arnott, J.A., Planey, S.L., The influence of lipophilicity in drug discovery and design. Expert Opin. Drug Discovery 7:10 (2012), 863–875.
    • (2012) Expert Opin. Drug Discovery , vol.7 , Issue.10 , pp. 863-875
    • Arnott, J.A.1    Planey, S.L.2
  • 56
    • 84888990081 scopus 로고    scopus 로고
    • Utilizing food effects to overcome challenges in delivery of lipophilic bioactives: structural design of medical and functional foods
    • McClements, D.J., Utilizing food effects to overcome challenges in delivery of lipophilic bioactives: structural design of medical and functional foods. Expert Opin. Drug Deliv. 10:12 (2013), 1621–1632.
    • (2013) Expert Opin. Drug Deliv. , vol.10 , Issue.12 , pp. 1621-1632
    • McClements, D.J.1
  • 57
    • 84922896315 scopus 로고    scopus 로고
    • Improving oral bioavailability of nutraceuticals by engineered nanoparticle-based delivery systems
    • Yao, M.F., McClements, D.J., Xiao, H., Improving oral bioavailability of nutraceuticals by engineered nanoparticle-based delivery systems. Curr. Opin. Food Sci. 2 (2015), 14–19.
    • (2015) Curr. Opin. Food Sci. , vol.2 , pp. 14-19
    • Yao, M.F.1    McClements, D.J.2    Xiao, H.3
  • 58
    • 84907632749 scopus 로고    scopus 로고
    • Nanoparticle- and Microparticle-based Delivery Systems: Encapsulation, Protection and Release of Active Components
    • CRC Press Boca Raton, FL
    • McClements, D.J., Nanoparticle- and Microparticle-based Delivery Systems: Encapsulation, Protection and Release of Active Components. 2015, CRC Press, Boca Raton, FL.
    • (2015)
    • McClements, D.J.1
  • 59
    • 84866143716 scopus 로고    scopus 로고
    • Physical barriers to carotenoid bioaccessibility. Ultrastructure survey of chromoplast and cell wall morphology in nine carotenoid-containing fruits and vegetables
    • Jeffery, J., Holzenburg, A., King, S., Physical barriers to carotenoid bioaccessibility. Ultrastructure survey of chromoplast and cell wall morphology in nine carotenoid-containing fruits and vegetables. J. Sci. Food Agric. 92:13 (2012), 2594–2602.
    • (2012) J. Sci. Food Agric. , vol.92 , Issue.13 , pp. 2594-2602
    • Jeffery, J.1    Holzenburg, A.2    King, S.3
  • 60
    • 33847784843 scopus 로고    scopus 로고
    • Food microstructure affects the bioavailability of several nutrients
    • Parada, J., Aguilera, J.M., Food microstructure affects the bioavailability of several nutrients. J. Food Sci. 72:2 (2007), R21–R32.
    • (2007) J. Food Sci. , vol.72 , Issue.2 , pp. R21-R32
    • Parada, J.1    Aguilera, J.M.2
  • 61
    • 84952976091 scopus 로고    scopus 로고
    • Carotenoids from fruits and vegetables: chemistry, analysis, occurrence: bioavailability and biological activities
    • Saini, R.K., Nile, S.H., Park, S.W., Carotenoids from fruits and vegetables: chemistry, analysis, occurrence: bioavailability and biological activities. Food Res. Int. 76 (2015), 735–750.
    • (2015) Food Res. Int. , vol.76 , pp. 735-750
    • Saini, R.K.1    Nile, S.H.2    Park, S.W.3
  • 64
    • 60149089459 scopus 로고    scopus 로고
    • Barrier properties of mucus
    • Cone, R.A., Barrier properties of mucus. Adv. Drug Deliv. Rev. 61:2 (2009), 75–85.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , Issue.2 , pp. 75-85
    • Cone, R.A.1
  • 65
    • 84858039015 scopus 로고    scopus 로고
    • The solubility-Permeability interplay and its implications in formulation design and development for poorly soluble drugs
    • Dahan, A., Miller, J.M., The solubility-Permeability interplay and its implications in formulation design and development for poorly soluble drugs. Aaps J. 14:2 (2012), 244–251.
    • (2012) Aaps J. , vol.14 , Issue.2 , pp. 244-251
    • Dahan, A.1    Miller, J.M.2
  • 68
    • 84903222032 scopus 로고    scopus 로고
    • Physicochemical basis of the digestion and absorption of triacylglycerol
    • Lo, C.M., Tso, P., Physicochemical basis of the digestion and absorption of triacylglycerol. Des. Funct. Foods, 2009, 94–125.
    • (2009) Des. Funct. Foods , pp. 94-125
    • Lo, C.M.1    Tso, P.2
  • 69
    • 1442357806 scopus 로고    scopus 로고
    • Enterocyte fatty acid uptake and intestinal fatty acid-binding protein
    • Tso, P., Nauli, A., Lo, C.M., Enterocyte fatty acid uptake and intestinal fatty acid-binding protein. Biochem. Soc. Trans. 32 (2004), 75–78.
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 75-78
    • Tso, P.1    Nauli, A.2    Lo, C.M.3
  • 70
    • 84886297700 scopus 로고    scopus 로고
    • Modulation of tight junction integrity by food components
    • Kosinska, A., Andlauer, W., Modulation of tight junction integrity by food components. Food Res. Int. 54:1 (2013), 951–960.
    • (2013) Food Res. Int. , vol.54 , Issue.1 , pp. 951-960
    • Kosinska, A.1    Andlauer, W.2
  • 71
    • 37849051383 scopus 로고    scopus 로고
    • Evaluation of the establishment of a tight junction in Caco-2 cell monolayers using a pore permeation model involving two different sizes
    • Seki, T., Harada, S., Hosoya, O., Morimoto, K., Juni, K., Evaluation of the establishment of a tight junction in Caco-2 cell monolayers using a pore permeation model involving two different sizes. Biol. Pharm. Bull. 31:1 (2008), 163–166.
    • (2008) Biol. Pharm. Bull. , vol.31 , Issue.1 , pp. 163-166
    • Seki, T.1    Harada, S.2    Hosoya, O.3    Morimoto, K.4    Juni, K.5
  • 72
    • 38349178006 scopus 로고    scopus 로고
    • Systematic studies on the paracellular permeation of model permeants and Oligonucleotides in the rat small intestine with chenodeoxycholate as enhancer
    • Tsutsumi, K., Li, S.K., Hymas, R.V., Teng, C.L., Tillman, L.G., Hardee, G.E., Higuchi, W.I., Ho, N.F.H., Systematic studies on the paracellular permeation of model permeants and Oligonucleotides in the rat small intestine with chenodeoxycholate as enhancer. J. Pharm. Sci. 97:1 (2008), 350–367.
    • (2008) J. Pharm. Sci. , vol.97 , Issue.1 , pp. 350-367
    • Tsutsumi, K.1    Li, S.K.2    Hymas, R.V.3    Teng, C.L.4    Tillman, L.G.5    Hardee, G.E.6    Higuchi, W.I.7    Ho, N.F.H.8
  • 73
    • 84933673955 scopus 로고    scopus 로고
    • Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease
    • Lerner, A., Matthias, T., Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease. Autoimmun. Rev. 14:6 (2015), 479–489.
    • (2015) Autoimmun. Rev. , vol.14 , Issue.6 , pp. 479-489
    • Lerner, A.1    Matthias, T.2
  • 74
    • 84861995150 scopus 로고    scopus 로고
    • Analysis of absorption enhancers in epithelial cell models
    • M. Fromm J.D. Schulzke Annals of the New York Academy of Sciences New York, NY
    • Rosenthal, R., Heydt, M.S., Amasheh, M., Stein, C., From, M., Amasheh, S., Analysis of absorption enhancers in epithelial cell models. Fromm, M., Schulzke, J.D., (eds.) Barriers and Channels Formed by Tight Junction Proteins II, vol. 1258, 2012, Annals of the New York Academy of Sciences, New York, NY, 86–92.
    • (2012) Barriers and Channels Formed by Tight Junction Proteins II , vol.1258 , pp. 86-92
    • Rosenthal, R.1    Heydt, M.S.2    Amasheh, M.3    Stein, C.4    From, M.5    Amasheh, S.6
  • 75
    • 77249093054 scopus 로고    scopus 로고
    • Interaction between food substances and the intestinal epithelium
    • Shimizu, M., Interaction between food substances and the intestinal epithelium. Biosci. Biotechnol. Biochem. 74:2 (2010), 232–241.
    • (2010) Biosci. Biotechnol. Biochem. , vol.74 , Issue.2 , pp. 232-241
    • Shimizu, M.1
  • 76
    • 84888203130 scopus 로고    scopus 로고
    • Clinical relevance of drug efflux pumps in the gut
    • Misaka, S., Muller, F., Fromm, M.F., Clinical relevance of drug efflux pumps in the gut. Curr. Opin. Pharmacol. 13:6 (2013), 847–852.
    • (2013) Curr. Opin. Pharmacol. , vol.13 , Issue.6 , pp. 847-852
    • Misaka, S.1    Muller, F.2    Fromm, M.F.3
  • 78
    • 84905391484 scopus 로고    scopus 로고
    • Oxidative cleavage products of lycopene: production and reactivity in a biomimetic experimental model of oxidative stress
    • P. Winterhalter S.E. Ebeler Amer Chemical Soc. Washington
    • Carail, M., Goupy, P., Reynaud, E., Dangles, O., Caris-Veyrat, C., Oxidative cleavage products of lycopene: production and reactivity in a biomimetic experimental model of oxidative stress. Winterhalter, P., Ebeler, S.E., (eds.) Carotenoid Cleavage Products, vol. 1134, 2013, Amer Chemical Soc., Washington, 191–205.
    • (2013) Carotenoid Cleavage Products , vol.1134 , pp. 191-205
    • Carail, M.1    Goupy, P.2    Reynaud, E.3    Dangles, O.4    Caris-Veyrat, C.5
  • 79
    • 84890503980 scopus 로고    scopus 로고
    • The initial characteristics of marine oil emulsions and the composition of the media inflect lipid oxidation during in vitro gastrointestinal digestion
    • Kenmogne-Domguia, H.B., Moisan, S., Viau, M., Genot, C., Meynier, A., The initial characteristics of marine oil emulsions and the composition of the media inflect lipid oxidation during in vitro gastrointestinal digestion. Food Chem. 152 (2014), 146–154.
    • (2014) Food Chem. , vol.152 , pp. 146-154
    • Kenmogne-Domguia, H.B.1    Moisan, S.2    Viau, M.3    Genot, C.4    Meynier, A.5
  • 80
    • 33645990883 scopus 로고    scopus 로고
    • Digestive stability, micellarization, and uptake of beta-carotene isomers by Caco-2 human intestinal cells
    • Ferruzzi, M.G., Lumpkin, J.L., Schwartz, S.J., Failla, M., Digestive stability, micellarization, and uptake of beta-carotene isomers by Caco-2 human intestinal cells. J. Agric. Food Chem. 54:7 (2006), 2780–2785.
    • (2006) J. Agric. Food Chem. , vol.54 , Issue.7 , pp. 2780-2785
    • Ferruzzi, M.G.1    Lumpkin, J.L.2    Schwartz, S.J.3    Failla, M.4
  • 81
    • 84894458572 scopus 로고    scopus 로고
    • Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery
    • Salem, M., Rohani, S., Gillies, E.R., Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery. RSC Adv. 4:21 (2014), 10815–10829.
    • (2014) RSC Adv. , vol.4 , Issue.21 , pp. 10815-10829
    • Salem, M.1    Rohani, S.2    Gillies, E.R.3
  • 82
    • 84867099595 scopus 로고    scopus 로고
    • The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters
    • Planas, J.M., Alfaras, I., Colom, H., Juan, M.E., The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters. Arch. Biochem. Biophys. 527:2 (2012), 67–73.
    • (2012) Arch. Biochem. Biophys. , vol.527 , Issue.2 , pp. 67-73
    • Planas, J.M.1    Alfaras, I.2    Colom, H.3    Juan, M.E.4
  • 84
    • 85028281947 scopus 로고    scopus 로고
    • Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells
    • Sun, Y., Wu, X., Cai, X.K., Song, M.Y., Zheng, J.K., Pan, C., Qiu, P.J., Zhang, L.J., Zhou, S.D., Tang, Z.H., Xiao, H., Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells. Mol. Nutr. Food Res. 60:9 (2016), 1924–1932.
    • (2016) Mol. Nutr. Food Res. , vol.60 , Issue.9 , pp. 1924-1932
    • Sun, Y.1    Wu, X.2    Cai, X.K.3    Song, M.Y.4    Zheng, J.K.5    Pan, C.6    Qiu, P.J.7    Zhang, L.J.8    Zhou, S.D.9    Tang, Z.H.10    Xiao, H.11
  • 85
    • 84952769409 scopus 로고    scopus 로고
    • Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis
    • Wu, X., Song, M., Wang, M., Zheng, J., Gao, Z., Xu, F., Zhang, G., Xiao, H., Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis. Mol. Nutr. Food Res. 59:12 (2015), 2383–2394.
    • (2015) Mol. Nutr. Food Res. , vol.59 , Issue.12 , pp. 2383-2394
    • Wu, X.1    Song, M.2    Wang, M.3    Zheng, J.4    Gao, Z.5    Xu, F.6    Zhang, G.7    Xiao, H.8
  • 86
  • 87
    • 72949123710 scopus 로고    scopus 로고
    • Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs
    • Dahan, A., Miller, J.M., Amidon, G.L., Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs. Aaps J. 11:4 (2009), 740–746.
    • (2009) Aaps J. , vol.11 , Issue.4 , pp. 740-746
    • Dahan, A.1    Miller, J.M.2    Amidon, G.L.3
  • 88
    • 80054697161 scopus 로고    scopus 로고
    • Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications
    • Kawabata, Y., Wada, K., Nakatani, M., Yamada, S., Onoue, S., Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications. Int. J. Pharm. 420:1 (2011), 1–10.
    • (2011) Int. J. Pharm. , vol.420 , Issue.1 , pp. 1-10
    • Kawabata, Y.1    Wada, K.2    Nakatani, M.3    Yamada, S.4    Onoue, S.5
  • 89
    • 14744272833 scopus 로고    scopus 로고
    • The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension
    • Lennernas, H., Abrahamsson, B., The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension. J. Pharm. Pharmacol. 57:3 (2005), 273–285.
    • (2005) J. Pharm. Pharmacol. , vol.57 , Issue.3 , pp. 273-285
    • Lennernas, H.1    Abrahamsson, B.2
  • 90
    • 84926508869 scopus 로고    scopus 로고
    • The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability
    • McClements, D.J., Li, F., Xiao, H., The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability. Ann. Rev. Food Sci. Technol., 6, 2015.
    • (2015) Ann. Rev. Food Sci. Technol. , vol.6
    • McClements, D.J.1    Li, F.2    Xiao, H.3
  • 91
    • 33644975006 scopus 로고    scopus 로고
    • Microemulsions: a potential delivery system for bioactives in food
    • Flanagan, J., Singh, H., Microemulsions: a potential delivery system for bioactives in food. Crit. Rev. Food Sci. Nutr. 46:3 (2006), 221–237.
    • (2006) Crit. Rev. Food Sci. Nutr. , vol.46 , Issue.3 , pp. 221-237
    • Flanagan, J.1    Singh, H.2
  • 92
    • 33846822906 scopus 로고    scopus 로고
    • Microemulsions as carriers for drugs and nutraceuticals
    • Spernath, A., Aserin, A., Microemulsions as carriers for drugs and nutraceuticals. Adv. Colloid Interface Sci. 128 (2006), 47–64.
    • (2006) Adv. Colloid Interface Sci. , vol.128 , pp. 47-64
    • Spernath, A.1    Aserin, A.2
  • 93
    • 84865354296 scopus 로고    scopus 로고
    • Advances in fabrication of emulsions with enhanced functionality using structural design principles
    • McClements, D.J., Advances in fabrication of emulsions with enhanced functionality using structural design principles. Curr. Opin. Colloid Interface Sci. 17:5 (2012), 235–245.
    • (2012) Curr. Opin. Colloid Interface Sci. , vol.17 , Issue.5 , pp. 235-245
    • McClements, D.J.1
  • 94
    • 79953217389 scopus 로고    scopus 로고
    • Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity
    • McClements, D.J., Rao, J., Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity. Crit. Rev. Food Sci. Nutr. 51:4 (2011), 285–330.
    • (2011) Crit. Rev. Food Sci. Nutr. , vol.51 , Issue.4 , pp. 285-330
    • McClements, D.J.1    Rao, J.2
  • 95
    • 84883027102 scopus 로고    scopus 로고
    • Utilization of solid lipid nanoparticles for enhanced delivery of curcumin in cocultures of HT29-MTX and Caco-2 cells
    • Guri, A., Guelseren, I., Corredig, M., Utilization of solid lipid nanoparticles for enhanced delivery of curcumin in cocultures of HT29-MTX and Caco-2 cells. Food Funct. 4:9 (2013), 1410–1419.
    • (2013) Food Funct. , vol.4 , Issue.9 , pp. 1410-1419
    • Guri, A.1    Guelseren, I.2    Corredig, M.3
  • 96
    • 84870252557 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: production: characterization and applications
    • Mehnert, W., Mader, K., Solid lipid nanoparticles: production: characterization and applications. Adv. Drug Deliv. Rev. 64 (2012), 83–101.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 83-101
    • Mehnert, W.1    Mader, K.2
  • 97
    • 33646008554 scopus 로고    scopus 로고
    • Food protein-based materials as nutraceutical delivery systems
    • Chen, L.Y., Remondetto, G.E., Subirade, M., Food protein-based materials as nutraceutical delivery systems. Trends iFood Sci. Technol. 17:5 (2006), 272–283.
    • (2006) Trends iFood Sci. Technol. , vol.17 , Issue.5 , pp. 272-283
    • Chen, L.Y.1    Remondetto, G.E.2    Subirade, M.3
  • 98
    • 84914708768 scopus 로고    scopus 로고
    • Biopolymer-based nanoparticles and microparticles: fabrication, characterization, and application
    • Joye, I.J., McClements, D.J., Biopolymer-based nanoparticles and microparticles: fabrication, characterization, and application. Curr. Opin. Colloid Interface Sci. 19:5 (2014), 417–427.
    • (2014) Curr. Opin. Colloid Interface Sci. , vol.19 , Issue.5 , pp. 417-427
    • Joye, I.J.1    McClements, D.J.2
  • 99
    • 84881281498 scopus 로고    scopus 로고
    • Review of techniques to manufacture micro-hydrogel particles for the food industry and their applications
    • Shewan, H.M., Stokes, J.R., Review of techniques to manufacture micro-hydrogel particles for the food industry and their applications. J. Food Eng. 119:4 (2013), 781–792.
    • (2013) J. Food Eng. , vol.119 , Issue.4 , pp. 781-792
    • Shewan, H.M.1    Stokes, J.R.2
  • 100
    • 84949526737 scopus 로고    scopus 로고
    • Enhancing nutraceutical bioavailability from raw and cooked vegetables using excipient emulsions: influence of lipid type on carotenoid bioaccessibility from carrots
    • Zhang, R.J., Zhang, Z.P., Zou, L.Q., Xiao, H., Zhang, G.D., Decker, E.A., McClements, D.J., Enhancing nutraceutical bioavailability from raw and cooked vegetables using excipient emulsions: influence of lipid type on carotenoid bioaccessibility from carrots. J. Agric. Food Chem. 63:48 (2015), 10508–10517.
    • (2015) J. Agric. Food Chem. , vol.63 , Issue.48 , pp. 10508-10517
    • Zhang, R.J.1    Zhang, Z.P.2    Zou, L.Q.3    Xiao, H.4    Zhang, G.D.5    Decker, E.A.6    McClements, D.J.7
  • 101
    • 84945468575 scopus 로고    scopus 로고
    • Designing hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract
    • Zhang, Z.P., Zhang, R.J., Chen, L., Tong, Q.Y., McClements, D.J., Designing hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract. Eur. Polym. J. 72 (2015), 698–716.
    • (2015) Eur. Polym. J. , vol.72 , pp. 698-716
    • Zhang, Z.P.1    Zhang, R.J.2    Chen, L.3    Tong, Q.Y.4    McClements, D.J.5
  • 102
    • 24344496972 scopus 로고    scopus 로고
    • Recent developments in microencapsulation of food ingredients
    • Desai, K.G.H., Park, H.J., Recent developments in microencapsulation of food ingredients. Drying Technol. 23:7 (2005), 1361–1394.
    • (2005) Drying Technol. , vol.23 , Issue.7 , pp. 1361-1394
    • Desai, K.G.H.1    Park, H.J.2
  • 103
    • 84355161742 scopus 로고    scopus 로고
    • Nanoencapsulation of food ingredients using lipid based delivery systems
    • Fathi, M., Mozafari, M.R., Mohebbi, M., Nanoencapsulation of food ingredients using lipid based delivery systems. Trends Food Sci. Technol. 23:1 (2012), 13–27.
    • (2012) Trends Food Sci. Technol. , vol.23 , Issue.1 , pp. 13-27
    • Fathi, M.1    Mozafari, M.R.2    Mohebbi, M.3
  • 104
  • 105
    • 84929240188 scopus 로고    scopus 로고
    • Enhancing nutraceutical bioavailability using excipient emulsions: influence of lipid droplet size on solubility and bioaccessibility of powdered curcumin
    • Zou, L.Q., Zheng, B.J., Liu, W., Liu, C.M., Xiao, H., McClements, D.J., Enhancing nutraceutical bioavailability using excipient emulsions: influence of lipid droplet size on solubility and bioaccessibility of powdered curcumin. J. Funct. Foods 15 (2015), 72–83.
    • (2015) J. Funct. Foods , vol.15 , pp. 72-83
    • Zou, L.Q.1    Zheng, B.J.2    Liu, W.3    Liu, C.M.4    Xiao, H.5    McClements, D.J.6
  • 106
    • 84879416298 scopus 로고    scopus 로고
    • Encapsulation of bioactive compounds in nanoemulsion-based delivery systems
    • G. Saravacos P. Taoukis M. Krokida V. Karathanos H. Lazarides N. Stoforos C. Tzia S. Yanniotis
    • Donsi, F., Sessa, M., Mediouni, H., Mgaidi, A., Ferrari, G., Encapsulation of bioactive compounds in nanoemulsion-based delivery systems. Saravacos, G., Taoukis, P., Krokida, M., Karathanos, V., Lazarides, H., Stoforos, N., Tzia, C., Yanniotis, S., (eds.) 11th International Congress on Engineering and Food, vol. 1, 2011, 1666–1671.
    • (2011) 11th International Congress on Engineering and Food , vol.1 , pp. 1666-1671
    • Donsi, F.1    Sessa, M.2    Mediouni, H.3    Mgaidi, A.4    Ferrari, G.5
  • 107
    • 84895070725 scopus 로고    scopus 로고
    • Nutraceutical-based therapeutics and formulation strategies augmenting their efficiency to complement modern medicine: an overview
    • Braithwaite, M.C., Tyagi, C., Tomar, L.K., Kumar, P., Choonara, Y.E., Pillay, V., Nutraceutical-based therapeutics and formulation strategies augmenting their efficiency to complement modern medicine: an overview. J. Funct. Foods 6 (2014), 82–99.
    • (2014) J. Funct. Foods , vol.6 , pp. 82-99
    • Braithwaite, M.C.1    Tyagi, C.2    Tomar, L.K.3    Kumar, P.4    Choonara, Y.E.5    Pillay, V.6
  • 109
    • 84945489189 scopus 로고    scopus 로고
    • Therapeutic applications of curcumin nanoformulations
    • Yallapu, M.M., Nagesh, P.K.B., Jaggi, M., Chauhan, S.C., Therapeutic applications of curcumin nanoformulations. Aaps J. 17:6 (2015), 1341–1356.
    • (2015) Aaps J. , vol.17 , Issue.6 , pp. 1341-1356
    • Yallapu, M.M.1    Nagesh, P.K.B.2    Jaggi, M.3    Chauhan, S.C.4
  • 110
    • 84904651099 scopus 로고    scopus 로고
    • Nutraceutical delivery systems: resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification
    • Davidov-Pardo, G., McClements, D.J., Nutraceutical delivery systems: resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification. Food Chem. 167 (2015), 205–212.
    • (2015) Food Chem. , vol.167 , pp. 205-212
    • Davidov-Pardo, G.1    McClements, D.J.2
  • 111
    • 84865718133 scopus 로고    scopus 로고
    • Inhibition of beta-carotene degradation in oil-in-water nanoemulsions: influence of oil-soluble and water-soluble antioxidants
    • Qian, C., Decker, E.A., Xiao, H., McClements, D.J., Inhibition of beta-carotene degradation in oil-in-water nanoemulsions: influence of oil-soluble and water-soluble antioxidants. Food Chem. 135:3 (2012), 1036–1043.
    • (2012) Food Chem. , vol.135 , Issue.3 , pp. 1036-1043
    • Qian, C.1    Decker, E.A.2    Xiao, H.3    McClements, D.J.4
  • 112
    • 84905401737 scopus 로고    scopus 로고
    • EDTA and alpha-tocopherol improve the chemical stability of astaxanthin loaded into nanostructured lipid carriers
    • Tamjidi, F., Shahedi, M., Varshosaz, J., Nasirpour, A., EDTA and alpha-tocopherol improve the chemical stability of astaxanthin loaded into nanostructured lipid carriers. Eur. J. Lipid Sci. Technol. 116:8 (2014), 968–977.
    • (2014) Eur. J. Lipid Sci. Technol. , vol.116 , Issue.8 , pp. 968-977
    • Tamjidi, F.1    Shahedi, M.2    Varshosaz, J.3    Nasirpour, A.4
  • 113
    • 84929485636 scopus 로고    scopus 로고
    • Nanoemulsion delivery systems for oil-soluble vitamins: influence of carrier oil type on lipid digestion and vitamin D-3 bioaccessibility
    • Ozturk, B., Argin, S., Ozilgen, M., McClements, D.J., Nanoemulsion delivery systems for oil-soluble vitamins: influence of carrier oil type on lipid digestion and vitamin D-3 bioaccessibility. Food Chem. 187 (2015), 499–506.
    • (2015) Food Chem. , vol.187 , pp. 499-506
    • Ozturk, B.1    Argin, S.2    Ozilgen, M.3    McClements, D.J.4
  • 114
    • 84875927050 scopus 로고    scopus 로고
    • Modulating beta-carotene bioaccessibility by controlling oil composition and concentration in edible nanoemulsions
    • Salvia-Trujillo, L., Qian, C., Martin-Belloso, O., McClements, D.J., Modulating beta-carotene bioaccessibility by controlling oil composition and concentration in edible nanoemulsions. Food Chem. 139:1–4 (2013), 878–884.
    • (2013) Food Chem. , vol.139 , Issue.1-4 , pp. 878-884
    • Salvia-Trujillo, L.1    Qian, C.2    Martin-Belloso, O.3    McClements, D.J.4
  • 115
    • 84938869067 scopus 로고    scopus 로고
    • In vitro and in vivo study of fucoxanthin bioavailability from nanoemulsion-based delivery systems: impact of lipid carrier type
    • Salvia-Trujillo, L., Sun, Q., Urn, B.H., Park, Y., McClements, D.J., In vitro and in vivo study of fucoxanthin bioavailability from nanoemulsion-based delivery systems: impact of lipid carrier type. J. Funct. Foods 17 (2015), 293–304.
    • (2015) J. Funct. Foods , vol.17 , pp. 293-304
    • Salvia-Trujillo, L.1    Sun, Q.2    Urn, B.H.3    Park, Y.4    McClements, D.J.5
  • 116
    • 84897727791 scopus 로고    scopus 로고
    • Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles
    • M.P. Doyle T.R. Klaenhammer
    • Yao, M.F., Xiao, H., McClements, D.J., Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles. Doyle, M.P., Klaenhammer, T.R., (eds.) Ann. Rev. Food Sci. Technol., 5, 2014, 53081.
    • (2014) Ann. Rev. Food Sci. Technol. , vol.5 , pp. 53081
    • Yao, M.F.1    Xiao, H.2    McClements, D.J.3
  • 118
    • 84969803568 scopus 로고    scopus 로고
    • Safety concerns over the use of intestinal permeation enhancers: a mini-review
    • McCartney, F., Gleeson, J.P., Brayden, D.J., Safety concerns over the use of intestinal permeation enhancers: a mini-review. Tissue Barriers, 4(2), 2016.
    • (2016) Tissue Barriers , vol.4 , Issue.2
    • McCartney, F.1    Gleeson, J.P.2    Brayden, D.J.3
  • 119
    • 84944205282 scopus 로고    scopus 로고
    • Enhancing nutraceutical performance using excipient foods: designing food structures and compositions to increase bioavailability
    • McClements, D.J., Zou, L.Q., Zhang, R.J., Salvia-Trujillo, L., Kumosani, T., Xiao, H., Enhancing nutraceutical performance using excipient foods: designing food structures and compositions to increase bioavailability. Compr. Rev. Food Sci. Food Saf. 14:6 (2015), 824–847.
    • (2015) Compr. Rev. Food Sci. Food Saf. , vol.14 , Issue.6 , pp. 824-847
    • McClements, D.J.1    Zou, L.Q.2    Zhang, R.J.3    Salvia-Trujillo, L.4    Kumosani, T.5    Xiao, H.6
  • 120
    • 84973924439 scopus 로고    scopus 로고
    • Improvement of beta-carotene bioaccessibility from dietary supplements using excipient nanoemulsions
    • Salvia-Trujillo, L., McClements, D.J., Improvement of beta-carotene bioaccessibility from dietary supplements using excipient nanoemulsions. J. Agric. Food Chem. 64:22 (2016), 4639–4647.
    • (2016) J. Agric. Food Chem. , vol.64 , Issue.22 , pp. 4639-4647
    • Salvia-Trujillo, L.1    McClements, D.J.2
  • 121
    • 84959472739 scopus 로고    scopus 로고
    • Enhancement of nutraceutical bioavailability using excipient nanoemulsions: role of lipid digestion products on bioaccessibility of carotenoids and phenolics from mangoes
    • Liu, X., Bi, J.F., Xiao, H., McClements, D.J., Enhancement of nutraceutical bioavailability using excipient nanoemulsions: role of lipid digestion products on bioaccessibility of carotenoids and phenolics from mangoes. J. Food Sci. 81:3 (2016), N754–N761.
    • (2016) J. Food Sci. , vol.81 , Issue.3 , pp. N754-N761
    • Liu, X.1    Bi, J.F.2    Xiao, H.3    McClements, D.J.4
  • 122
    • 84942673049 scopus 로고    scopus 로고
    • Increasing carotenoid bioaccessibility from yellow peppers using excipient emulsions: impact of lipid type and thermal processing
    • Liu, X., Bi, J.F., Xiao, H., McClements, D.J., Increasing carotenoid bioaccessibility from yellow peppers using excipient emulsions: impact of lipid type and thermal processing. J. Agric. Food Chem. 63:38 (2015), 8534–8543.
    • (2015) J. Agric. Food Chem. , vol.63 , Issue.38 , pp. 8534-8543
    • Liu, X.1    Bi, J.F.2    Xiao, H.3    McClements, D.J.4
  • 123
    • 84964711887 scopus 로고    scopus 로고
    • Enhancement of lycopene bioaccessibility from tomato juice using excipient emulsions: influence of lipid droplet size
    • Salvia-Trujillo, L., McClements, D.J., Enhancement of lycopene bioaccessibility from tomato juice using excipient emulsions: influence of lipid droplet size. Food Chem. 210 (2016), 295–304.
    • (2016) Food Chem. , vol.210 , pp. 295-304
    • Salvia-Trujillo, L.1    McClements, D.J.2
  • 124
    • 84896706625 scopus 로고    scopus 로고
    • Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and Coenzyme Q10
    • Cho, H.T., Salvia-Trujillo, L., Kim, J., Park, Y., Xiao, H., McClements, D., Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and Coenzyme Q10. Food Chem. 156 (2014), 117–122.
    • (2014) Food Chem. , vol.156 , pp. 117-122
    • Cho, H.T.1    Salvia-Trujillo, L.2    Kim, J.3    Park, Y.4    Xiao, H.5    McClements, D.6
  • 125
    • 84956648448 scopus 로고    scopus 로고
    • Enhancement of carotenoid bioaccessibility from carrots using excipient emulsions: influence of particle size of digestible lipid droplets
    • Zhang, R.J., Zhang, Z.P., Zou, L.Q., Xiao, H., Zhang, G.D., Decker, E.A., McClements, D.J., Enhancement of carotenoid bioaccessibility from carrots using excipient emulsions: influence of particle size of digestible lipid droplets. Food Funct. 7:1 (2016), 93–103.
    • (2016) Food Funct. , vol.7 , Issue.1 , pp. 93-103
    • Zhang, R.J.1    Zhang, Z.P.2    Zou, L.Q.3    Xiao, H.4    Zhang, G.D.5    Decker, E.A.6    McClements, D.J.7
  • 126
    • 84893483332 scopus 로고    scopus 로고
    • Characterization and bioavailability of tea polyphenol nanoliposome prepared by combining an ethanol injection method with dynamic high-pressure microfluidization
    • Zou, L.Q., Liu, W., Liu, W.L., Liang, R.H., Li, T., Liu, C.M., Cao, Y.L., Niu, J., Liu, Z., Characterization and bioavailability of tea polyphenol nanoliposome prepared by combining an ethanol injection method with dynamic high-pressure microfluidization. J. Agric. Food Chem. 62:4 (2014), 934–941.
    • (2014) J. Agric. Food Chem. , vol.62 , Issue.4 , pp. 934-941
    • Zou, L.Q.1    Liu, W.2    Liu, W.L.3    Liang, R.H.4    Li, T.5    Liu, C.M.6    Cao, Y.L.7    Niu, J.8    Liu, Z.9
  • 127
    • 84938803763 scopus 로고    scopus 로고
    • Designing excipient emulsions to increase nutraceutical bioavailability: emulsifier type influences curcumin stability and bioaccessibility by altering gastrointestinal fate
    • Zou, L.Q., Liu, W., Liu, C.M., Xiao, H., McClements, D.J., Designing excipient emulsions to increase nutraceutical bioavailability: emulsifier type influences curcumin stability and bioaccessibility by altering gastrointestinal fate. Food Funct. 6:8 (2015), 2475–2486.
    • (2015) Food Funct. , vol.6 , Issue.8 , pp. 2475-2486
    • Zou, L.Q.1    Liu, W.2    Liu, C.M.3    Xiao, H.4    McClements, D.J.5
  • 128
    • 85016141071 scopus 로고    scopus 로고
    • Deceptive curcumin offers cautionary tale for chemists
    • Baker, M., Deceptive curcumin offers cautionary tale for chemists. Nature 541 (2017), 144–145.
    • (2017) Nature , vol.541 , pp. 144-145
    • Baker, M.1


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