-
1
-
-
12744278308
-
Cruciferous vegetables, genetic polymorphisms in glutathione s-transferases m1 and t1, and prostate cancer risk
-
Joseph M.A., Moysich K.B., Freudenheim J.L., Shields P.G., Bowman E.D., Zhang Y., Marshall J.R., and Ambrosone C.B. Cruciferous vegetables, genetic polymorphisms in glutathione s-transferases m1 and t1, and prostate cancer risk. Nutr. Cancer 50 (2004) 206-213
-
(2004)
Nutr. Cancer
, vol.50
, pp. 206-213
-
-
Joseph, M.A.1
Moysich, K.B.2
Freudenheim, J.L.3
Shields, P.G.4
Bowman, E.D.5
Zhang, Y.6
Marshall, J.R.7
Ambrosone, C.B.8
-
2
-
-
0031857919
-
Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas
-
Lin H.J., Probst-Hensch N.M., Louie A.D., Kau I.H., Witte J.S., Ingles S.A., Frankl H.D., Lee E.R., and Haile R.W. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. Cancer Epidemiol. Biomarkers Prev. 7 (1998) 647-652
-
(1998)
Cancer Epidemiol. Biomarkers Prev.
, vol.7
, pp. 647-652
-
-
Lin, H.J.1
Probst-Hensch, N.M.2
Louie, A.D.3
Kau, I.H.4
Witte, J.S.5
Ingles, S.A.6
Frankl, H.D.7
Lee, E.R.8
Haile, R.W.9
-
3
-
-
0032935663
-
Variation of glucosinolates in vegetable crops of Brassica oleracea
-
Mosbah A.F.B., Kushad M., Kurilich A.C., Juvik J.A., Klein B.P., Wallig M.A., and Jeffrey E.H. Variation of glucosinolates in vegetable crops of Brassica oleracea. J. Agric. Food Chem. 47 (1999) 1541-1548
-
(1999)
J. Agric. Food Chem.
, vol.47
, pp. 1541-1548
-
-
Mosbah, A.F.B.1
Kushad, M.2
Kurilich, A.C.3
Juvik, J.A.4
Klein, B.P.5
Wallig, M.A.6
Jeffrey, E.H.7
-
4
-
-
0035155096
-
Glucosinolates - biochemistry, genetics and biological activity
-
Mithen R. Glucosinolates - biochemistry, genetics and biological activity. Plant Growth Regul. 34 (2001) 91-103
-
(2001)
Plant Growth Regul.
, vol.34
, pp. 91-103
-
-
Mithen, R.1
-
5
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure
-
Zhang Y., Talalay P., Cho C.G., and Posner G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc. Natl. Acad. Sci. USA 89 (1992) 2399-2403
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
6
-
-
34047136753
-
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
-
Higdon J.V., Delage B., Williams D.E., and Dashwood R.H. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol. Res. 55 (2007) 224-236
-
(2007)
Pharmacol. Res.
, vol.55
, pp. 224-236
-
-
Higdon, J.V.1
Delage, B.2
Williams, D.E.3
Dashwood, R.H.4
-
7
-
-
34247606510
-
Molecular basis for chemoprevention by sulforaphane: a comprehensive review
-
Juge N., Mithen R.F., and Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol. Life Sci. 64 (2007) 1105-1127
-
(2007)
Cell Mol. Life Sci.
, vol.64
, pp. 1105-1127
-
-
Juge, N.1
Mithen, R.F.2
Traka, M.3
-
8
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure
-
Zhang Y., Talalay P., Cho C.G., and Posner G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc. Natl. Acad. Sci. USA 89 (1992) 2399-2403
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
9
-
-
0030852501
-
Inhibition of cytochromes p-450 and induction of glutathione s-transferases by sulforaphane in primary human and rat hepatocytes
-
Maheo K., Morel F., Langouet S., Kramer H., Le Ferrec E., Ketterer B., and Guillouzo A. Inhibition of cytochromes p-450 and induction of glutathione s-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 57 (1997) 3649-3652
-
(1997)
Cancer Res.
, vol.57
, pp. 3649-3652
-
-
Maheo, K.1
Morel, F.2
Langouet, S.3
Kramer, H.4
Le Ferrec, E.5
Ketterer, B.6
Guillouzo, A.7
-
10
-
-
33644646401
-
Chemoprotection by sulforaphane: keep one eye beyond keap1
-
Myzak M.C., and Dashwood R.H. Chemoprotection by sulforaphane: keep one eye beyond keap1. Cancer Lett. 233 (2006) 208-218
-
(2006)
Cancer Lett.
, vol.233
, pp. 208-218
-
-
Myzak, M.C.1
Dashwood, R.H.2
-
11
-
-
0034854057
-
Potent induction of phase 2 enzymes in human prostate cells by sulforaphane
-
Brooks J.D., Paton V.G., and Vidanes G. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane. Cancer Epidemiol. Biomarkers Prev. 10 (2001) 949-954
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 949-954
-
-
Brooks, J.D.1
Paton, V.G.2
Vidanes, G.3
-
12
-
-
0037947696
-
Food matrix effects on bioactivity of broccoli-derived sulforaphane in liver and colon of f344 rats
-
Keck A.S., Qiao Q., and Jeffery E.H. Food matrix effects on bioactivity of broccoli-derived sulforaphane in liver and colon of f344 rats. J. Agric. Food Chem. 51 (2003) 3320-3327
-
(2003)
J. Agric. Food Chem.
, vol.51
, pp. 3320-3327
-
-
Keck, A.S.1
Qiao, Q.2
Jeffery, E.H.3
-
13
-
-
33645468736
-
Modest induction of phase 2 enzyme activity in the f-344 rat prostate
-
Jones S.B., and Brooks J.D. Modest induction of phase 2 enzyme activity in the f-344 rat prostate. BMC Cancer 6 (2006) 62
-
(2006)
BMC Cancer
, vol.6
, pp. 62
-
-
Jones, S.B.1
Brooks, J.D.2
-
14
-
-
0037518134
-
Absorption/metabolism of sulforaphane and quercetin, and regulation of phase ii enzymes, in human jejunum in vivo
-
Petri N., Tannergren C., Holst B., Mellon F.A., Bao Y., Plumb G.W., Bacon J., O'Leary K.A., Kroon P.A., Knutson L., Forsell P., Eriksson T., Lennernas H., and Williamson G. Absorption/metabolism of sulforaphane and quercetin, and regulation of phase ii enzymes, in human jejunum in vivo. Drug Metab. Dispos. 31 (2003) 805-813
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 805-813
-
-
Petri, N.1
Tannergren, C.2
Holst, B.3
Mellon, F.A.4
Bao, Y.5
Plumb, G.W.6
Bacon, J.7
O'Leary, K.A.8
Kroon, P.A.9
Knutson, L.10
Forsell, P.11
Eriksson, T.12
Lennernas, H.13
Williamson, G.14
-
15
-
-
0037106099
-
Identification of nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., and Biswal S. Identification of nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 62 (2002) 5196-5203
-
(2002)
Cancer Res.
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
16
-
-
33746889956
-
Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of c57bl/6j mice and c57bl/6j/nrf2 (-/-) mice
-
Hu R., Xu C., Shen G., Jain M.R., Khor T.O., Gopalkrishnan A., Lin W., Reddy B., Chan J.Y., and Kong A.N. Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of c57bl/6j mice and c57bl/6j/nrf2 (-/-) mice. Cancer Lett. 243 (2006) 170-192
-
(2006)
Cancer Lett.
, vol.243
, pp. 170-192
-
-
Hu, R.1
Xu, C.2
Shen, G.3
Jain, M.R.4
Khor, T.O.5
Gopalkrishnan, A.6
Lin, W.7
Reddy, B.8
Chan, J.Y.9
Kong, A.N.10
-
17
-
-
9744283511
-
Transcription factor nrf2 is essential for induction of nad(p)h:quinone oxidoreductase 1, glutathione s-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates
-
McWalter G.K., Higgins L.G., McLellan L.I., Henderson C.J., Song L., Thornalley P.J., Itoh K., Yamamoto M., and Hayes J.D. Transcription factor nrf2 is essential for induction of nad(p)h:quinone oxidoreductase 1, glutathione s-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates. J. Nutr. 134 (2004) 3499S-3506S
-
(2004)
J. Nutr.
, vol.134
-
-
McWalter, G.K.1
Higgins, L.G.2
McLellan, L.I.3
Henderson, C.J.4
Song, L.5
Thornalley, P.J.6
Itoh, K.7
Yamamoto, M.8
Hayes, J.D.9
-
18
-
-
2942614713
-
Sulforaphane-induced g2/m phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25c
-
Singh S.V., Herman-Antosiewicz A., Singh A.V., Lew K.L., Srivastava S.K., Kamath R., Brown K.D., Zhang L., and Baskaran R. Sulforaphane-induced g2/m phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25c. J. Biol. Chem. 279 (2004) 25813-25822
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25813-25822
-
-
Singh, S.V.1
Herman-Antosiewicz, A.2
Singh, A.V.3
Lew, K.L.4
Srivastava, S.K.5
Kamath, R.6
Brown, K.D.7
Zhang, L.8
Baskaran, R.9
-
19
-
-
34250757157
-
Induction of p21 protein protects against sulforaphane-induced mitotic arrest in lncap human prostate cancer cell line
-
Herman-Antosiewicz A., Xiao H., Lew K.L., and Singh S.V. Induction of p21 protein protects against sulforaphane-induced mitotic arrest in lncap human prostate cancer cell line. Mol. Cancer Ther. 6 (2007) 1673-1681
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1673-1681
-
-
Herman-Antosiewicz, A.1
Xiao, H.2
Lew, K.L.3
Singh, S.V.4
-
20
-
-
27644553527
-
Involvement of c-jun N-terminal kinase in g2/m arrest and caspase-mediated apoptosis induced by sulforaphane in du145 prostate cancer cells
-
Cho S.D., Li G., Hu H., Jiang C., Kang K.S., Lee Y.S., Kim S.H., and Lu J. Involvement of c-jun N-terminal kinase in g2/m arrest and caspase-mediated apoptosis induced by sulforaphane in du145 prostate cancer cells. Nutr. Cancer 52 (2005) 213-224
-
(2005)
Nutr. Cancer
, vol.52
, pp. 213-224
-
-
Cho, S.D.1
Li, G.2
Hu, H.3
Jiang, C.4
Kang, K.S.5
Lee, Y.S.6
Kim, S.H.7
Lu, J.8
-
21
-
-
3843082891
-
Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells
-
Parnaud G., Li P., Cassar G., Rouimi P., Tulliez J., Combaret L., and Gamet-Payrastre L. Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells. Nutr. Cancer 48 (2004) 198-206
-
(2004)
Nutr. Cancer
, vol.48
, pp. 198-206
-
-
Parnaud, G.1
Li, P.2
Cassar, G.3
Rouimi, P.4
Tulliez, J.5
Combaret, L.6
Gamet-Payrastre, L.7
-
22
-
-
0034162822
-
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in ht29 human colon cancer cells
-
Gamet-Payrastre L., Li P., Lumeau S., Cassar G., Dupont M.-A., Chevolleau S., Gasc N., Tulliez J., and Terce F. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in ht29 human colon cancer cells. Cancer Res. 60 (2000) 1426-1433
-
(2000)
Cancer Res.
, vol.60
, pp. 1426-1433
-
-
Gamet-Payrastre, L.1
Li, P.2
Lumeau, S.3
Cassar, G.4
Dupont, M.-A.5
Chevolleau, S.6
Gasc, N.7
Tulliez, J.8
Terce, F.9
-
23
-
-
33644841610
-
P53-independent g1 cell cycle arrest of human colon carcinoma cells ht-29 by sulforaphane is associated with induction of p21cip1 and inhibition of expression of cyclin d1
-
Shen G., Xu C., Chen C., Hebbar V., and Kong A.-N. P53-independent g1 cell cycle arrest of human colon carcinoma cells ht-29 by sulforaphane is associated with induction of p21cip1 and inhibition of expression of cyclin d1. Cancer Chemother. Pharmacol. 57 (2006) 317-327
-
(2006)
Cancer Chemother. Pharmacol.
, vol.57
, pp. 317-327
-
-
Shen, G.1
Xu, C.2
Chen, C.3
Hebbar, V.4
Kong, A.-N.5
-
24
-
-
0036511358
-
Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells
-
Chiao J.W., Chung F.L., Kancherla R., Ahmed T., Mittelman A., and Conaway C.C. Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells. Int. J. Oncol. 20 (2002) 631-636
-
(2002)
Int. J. Oncol.
, vol.20
, pp. 631-636
-
-
Chiao, J.W.1
Chung, F.L.2
Kancherla, R.3
Ahmed, T.4
Mittelman, A.5
Conaway, C.C.6
-
25
-
-
3843072178
-
Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention
-
Wang L., Liu D., Ahmed T., Chung F.L., Conaway C., and Chiao J.W. Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention. Int. J. Oncol. 24 (2004) 187-192
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 187-192
-
-
Wang, L.1
Liu, D.2
Ahmed, T.3
Chung, F.L.4
Conaway, C.5
Chiao, J.W.6
-
26
-
-
19344367171
-
Role of pi3k/akt and mek/erk signaling pathways in sulforaphane- and erucin-induced phase ii enzymes and mrp2 transcription, g2/m arrest and cell death in caco-2 cells
-
Jakubikova J., Sedlak J., Mithen R., and Bao Y. Role of pi3k/akt and mek/erk signaling pathways in sulforaphane- and erucin-induced phase ii enzymes and mrp2 transcription, g2/m arrest and cell death in caco-2 cells. Biochem. Pharmacol. 69 (2005) 1543-1552
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 1543-1552
-
-
Jakubikova, J.1
Sedlak, J.2
Mithen, R.3
Bao, Y.4
-
27
-
-
34548106014
-
Biphasic modulation of cell proliferation by sulforaphane at physiologically relevant exposure times in a human colon cancer cell line
-
Pappa G., Bartsch H., and Gerhäuser C. Biphasic modulation of cell proliferation by sulforaphane at physiologically relevant exposure times in a human colon cancer cell line. Mol. Nutr. Food Res. 51 (2007) 977-984
-
(2007)
Mol. Nutr. Food Res.
, vol.51
, pp. 977-984
-
-
Pappa, G.1
Bartsch, H.2
Gerhäuser, C.3
-
28
-
-
23244450241
-
Transcriptome analysis of human colon caco-2 cells exposed to sulforaphane
-
Traka M., Gasper A.V., Smith J.A., Hawkey C.J., Bao Y., and Mithen R.F. Transcriptome analysis of human colon caco-2 cells exposed to sulforaphane. J. Nutr. 135 (2005) 1865-1872
-
(2005)
J. Nutr.
, vol.135
, pp. 1865-1872
-
-
Traka, M.1
Gasper, A.V.2
Smith, J.A.3
Hawkey, C.J.4
Bao, Y.5
Mithen, R.F.6
-
29
-
-
33645324413
-
Sulforaphane inhibits histone deacetylase activity in bph-1, lncap and pc-3 prostate epithelial cells
-
Myzak M.C., Hardin K., Wang R., Dashwood R.H., and Ho E. Sulforaphane inhibits histone deacetylase activity in bph-1, lncap and pc-3 prostate epithelial cells. Carcinogenesis 27 (2006) 811-819
-
(2006)
Carcinogenesis
, vol.27
, pp. 811-819
-
-
Myzak, M.C.1
Hardin, K.2
Wang, R.3
Dashwood, R.H.4
Ho, E.5
-
30
-
-
33745875948
-
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from brassicaceae
-
Pappa G., Lichtenberg M., Iori R., Barillari J., Bartsch H., and Gerhauser C. Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from brassicaceae. Mutat. Res. 599 (2006) 76-87
-
(2006)
Mutat. Res.
, vol.599
, pp. 76-87
-
-
Pappa, G.1
Lichtenberg, M.2
Iori, R.3
Barillari, J.4
Bartsch, H.5
Gerhauser, C.6
-
31
-
-
1642545614
-
Sulforaphane induces caspase-mediated apoptosis in cultured pc-3 human prostate cancer cells and retards growth of pc-3 xenografts in vivo
-
Singh A.V., Xiao D., Lew K.L., Dhir R., and Singh S.V. Sulforaphane induces caspase-mediated apoptosis in cultured pc-3 human prostate cancer cells and retards growth of pc-3 xenografts in vivo. Carcinogenesis 25 (2004) 83-90
-
(2004)
Carcinogenesis
, vol.25
, pp. 83-90
-
-
Singh, A.V.1
Xiao, D.2
Lew, K.L.3
Dhir, R.4
Singh, S.V.5
-
32
-
-
1842631408
-
Upregulation and nuclear recruitment of hdac1 in hormone refractory prostate cancer
-
Halkidou K., Gaughan L., Cook S., Leung H.Y., Neal D.E., and Robson C.N. Upregulation and nuclear recruitment of hdac1 in hormone refractory prostate cancer. Prostate 59 (2004) 177-189
-
(2004)
Prostate
, vol.59
, pp. 177-189
-
-
Halkidou, K.1
Gaughan, L.2
Cook, S.3
Leung, H.Y.4
Neal, D.E.5
Robson, C.N.6
-
33
-
-
34547100073
-
Sirt1 is significantly elevated in mouse and human prostate cancer
-
Huffman D.M., Grizzle W.E., Bamman M.M., Kim J.-s., Eltoum I.A., Elgavish A., and Nagy T.R. Sirt1 is significantly elevated in mouse and human prostate cancer. Cancer Res. 67 (2007) 6612-6618
-
(2007)
Cancer Res.
, vol.67
, pp. 6612-6618
-
-
Huffman, D.M.1
Grizzle, W.E.2
Bamman, M.M.3
Kim, J.-s.4
Eltoum, I.A.5
Elgavish, A.6
Nagy, T.R.7
-
34
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
Seligson D.B., Horvath S., Shi T., Yu H., Tze S., Grunstein M., and Kurdistani S.K. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435 (2005) 1262-1266
-
(2005)
Nature
, vol.435
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
35
-
-
2342603414
-
Induction of hdac2 expression upon loss of apc in colorectal tumorigenesis
-
Zhu P., Martin E., Mengwasser J., Schlag P., Janssen K.-P., and Gottlicher M. Induction of hdac2 expression upon loss of apc in colorectal tumorigenesis. Cancer Cell 5 (2004) 455-463
-
(2004)
Cancer Cell
, vol.5
, pp. 455-463
-
-
Zhu, P.1
Martin, E.2
Mengwasser, J.3
Schlag, P.4
Janssen, K.-P.5
Gottlicher, M.6
-
36
-
-
0036527775
-
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer
-
Johnstone R.W. Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat. Rev. Drug Discov. 1 (2002) 287-299
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 287-299
-
-
Johnstone, R.W.1
-
37
-
-
4143130097
-
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase
-
Myzak M.C., Karplus P.A., Chung F.L., and Dashwood R.H. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res. 64 (2004) 5767-5774
-
(2004)
Cancer Res.
, vol.64
, pp. 5767-5774
-
-
Myzak, M.C.1
Karplus, P.A.2
Chung, F.L.3
Dashwood, R.H.4
-
38
-
-
34548456881
-
Dietary histone deacetylase inhibitors: from cells to mice to man
-
Dashwood R.H., and Ho E. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin. Cancer Biol. 17 (2007) 363-369
-
(2007)
Semin. Cancer Biol.
, vol.17
, pp. 363-369
-
-
Dashwood, R.H.1
Ho, E.2
-
39
-
-
33645825587
-
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in apc-minus mice
-
Myzak M.C., Dashwood W.M., Orner G.A., Ho E., and Dashwood R.H. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in apc-minus mice. FASEB J. 20 (2006) 506-508
-
(2006)
FASEB J.
, vol.20
, pp. 506-508
-
-
Myzak, M.C.1
Dashwood, W.M.2
Orner, G.A.3
Ho, E.4
Dashwood, R.H.5
-
40
-
-
1842607591
-
Modulation of ap-1 by natural chemopreventive compounds in human colon ht-29 cancer cell line
-
Jeong W.S., Kim I.W., Hu R., and Kong A.N. Modulation of ap-1 by natural chemopreventive compounds in human colon ht-29 cancer cell line. Pharm. Res. 21 (2004) 649-660
-
(2004)
Pharm. Res.
, vol.21
, pp. 649-660
-
-
Jeong, W.S.1
Kim, I.W.2
Hu, R.3
Kong, A.N.4
-
41
-
-
33644865443
-
Erk and jnk signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer pc-3 cells
-
Xu C., Shen G., Yuan X., Kim J.H., Gopalkrishnan A., Keum Y.S., Nair S., and Kong A.N. Erk and jnk signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer pc-3 cells. Carcinogenesis 27 (2006) 437-445
-
(2006)
Carcinogenesis
, vol.27
, pp. 437-445
-
-
Xu, C.1
Shen, G.2
Yuan, X.3
Kim, J.H.4
Gopalkrishnan, A.5
Keum, Y.S.6
Nair, S.7
Kong, A.N.8
-
42
-
-
33749019130
-
Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma hepg2 cells
-
Keum Y.-S., Yu S., Chang P.P.-J., Yuan X., Kim J.-H., Xu C., Han J., Agarwal A., and Kong A.-N.T. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma hepg2 cells. Cancer Res. 66 (2006) 8804-8813
-
(2006)
Cancer Res.
, vol.66
, pp. 8804-8813
-
-
Keum, Y.-S.1
Yu, S.2
Chang, P.P.-J.3
Yuan, X.4
Kim, J.-H.5
Xu, C.6
Han, J.7
Agarwal, A.8
Kong, A.-N.T.9
-
43
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet B., and Gelinas C. Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18 (1999) 6938-6947
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
44
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor nf-{{kappa}}b
-
Baldwin A.S. Control of oncogenesis and cancer therapy resistance by the transcription factor nf-{{kappa}}b. J. Clin. Invest. 107 (2001) 241-246
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
45
-
-
33845623882
-
d,l-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and apaf-1
-
Choi S., Lew K.L., Xiao H., Herman-Antosiewicz A., Xiao D., Brown C.K., and Singh S.V. d,l-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and apaf-1. Carcinogenesis 28 (2007) 151-162
-
(2007)
Carcinogenesis
, vol.28
, pp. 151-162
-
-
Choi, S.1
Lew, K.L.2
Xiao, H.3
Herman-Antosiewicz, A.4
Xiao, D.5
Brown, C.K.6
Singh, S.V.7
-
46
-
-
22744440329
-
Suppression of nf-kappab and nf-kappab-regulated gene expression by sulforaphane and peitc through ikappabalpha, ikk pathway in human prostate cancer pc-3 cells
-
Xu C., Shen G., Chen C., Gelinas C., and Kong A.N. Suppression of nf-kappab and nf-kappab-regulated gene expression by sulforaphane and peitc through ikappabalpha, ikk pathway in human prostate cancer pc-3 cells. Oncogene 24 (2005) 4486-4495
-
(2005)
Oncogene
, vol.24
, pp. 4486-4495
-
-
Xu, C.1
Shen, G.2
Chen, C.3
Gelinas, C.4
Kong, A.N.5
-
47
-
-
1842555356
-
Modulatory properties of various natural chemopreventive agents on the activation of nf-kappab signaling pathway
-
Jeong W.S., Kim I.W., Hu R., and Kong A.N. Modulatory properties of various natural chemopreventive agents on the activation of nf-kappab signaling pathway. Pharm. Res. 21 (2004) 661-670
-
(2004)
Pharm. Res.
, vol.21
, pp. 661-670
-
-
Jeong, W.S.1
Kim, I.W.2
Hu, R.3
Kong, A.N.4
-
48
-
-
21244461140
-
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species
-
Singh S.V., Srivastava S.K., Choi S., Lew K.L., Antosiewicz J., Xiao D., Zeng Y., Watkins S.C., Johnson C.S., Trump D.L., Lee Y.J., Xiao H., and Herman-Antosiewicz A. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J. Biol. Chem. 280 (2005) 19911-19924
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19911-19924
-
-
Singh, S.V.1
Srivastava, S.K.2
Choi, S.3
Lew, K.L.4
Antosiewicz, J.5
Xiao, D.6
Zeng, Y.7
Watkins, S.C.8
Johnson, C.S.9
Trump, D.L.10
Lee, Y.J.11
Xiao, H.12
Herman-Antosiewicz, A.13
-
49
-
-
33745282435
-
Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells
-
Herman-Antosiewicz A., Johnson D.E., and Singh S.V. Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells. Cancer Res. 66 (2006) 5828-5835
-
(2006)
Cancer Res.
, vol.66
, pp. 5828-5835
-
-
Herman-Antosiewicz, A.1
Johnson, D.E.2
Singh, S.V.3
-
50
-
-
0000295679
-
The myrosinase-glucosinolate system, its organisation and biochemistry
-
Bones A.M., and Rossiter J.T. The myrosinase-glucosinolate system, its organisation and biochemistry. Physiologia Plantarum 97 (1996) 194-208
-
(1996)
Physiologia Plantarum
, vol.97
, pp. 194-208
-
-
Bones, A.M.1
Rossiter, J.T.2
-
51
-
-
0030781225
-
Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase i metabolites and glutathione conjugates
-
Kassahun K., Davis M., Hu P., Martin B., and Baillie T. Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase i metabolites and glutathione conjugates. Chem. Res. Toxicol. 10 (1997) 1228-1233
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 1228-1233
-
-
Kassahun, K.1
Davis, M.2
Hu, P.3
Martin, B.4
Baillie, T.5
-
52
-
-
0034434321
-
Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli
-
Conaway C.C., Getahun S.M., Liebes L.L., Pusateri D.J., Topham D.K.W., Botero-Omary M., and Chung F.-L. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nutr. Cancer 38 (2000) 168-178
-
(2000)
Nutr. Cancer
, vol.38
, pp. 168-178
-
-
Conaway, C.C.1
Getahun, S.M.2
Liebes, L.L.3
Pusateri, D.J.4
Topham, D.K.W.5
Botero-Omary, M.6
Chung, F.-L.7
-
53
-
-
0032406798
-
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables
-
Shapiro T.A., Fahey J.W., Wade K.L., Stephenson K.K., and Talalay P. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol. Biomarkers Prev. 7 (1998) 1091-1100
-
(1998)
Cancer Epidemiol. Biomarkers Prev.
, vol.7
, pp. 1091-1100
-
-
Shapiro, T.A.1
Fahey, J.W.2
Wade, K.L.3
Stephenson, K.K.4
Talalay, P.5
-
54
-
-
34247626240
-
The metabolic fate of purified glucoraphanin in f344 rats
-
Bheemreddy R.M., and Jeffery E.H. The metabolic fate of purified glucoraphanin in f344 rats. J. Agric. Food Chem. 55 (2007) 2861-2866
-
(2007)
J. Agric. Food Chem.
, vol.55
, pp. 2861-2866
-
-
Bheemreddy, R.M.1
Jeffery, E.H.2
-
55
-
-
0034928041
-
Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans
-
Shapiro T.A., Fahey J.W., Wade K.L., Stephenson K.K., and Talalay P. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. Cancer Epidemiol. Biomarkers Prev. 10 (2001) 501-508
-
(2001)
Cancer Epidemiol. Biomarkers Prev.
, vol.10
, pp. 501-508
-
-
Shapiro, T.A.1
Fahey, J.W.2
Wade, K.L.3
Stephenson, K.K.4
Talalay, P.5
-
56
-
-
28244459182
-
Effect of glutathione-s-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective
-
Seow A., Vainio H., and Yu M.C. Effect of glutathione-s-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective. Mutat. Res. 592 (2005) 58-67
-
(2005)
Mutat. Res.
, vol.592
, pp. 58-67
-
-
Seow, A.1
Vainio, H.2
Yu, M.C.3
-
57
-
-
0036792160
-
Brassica, biotransformation and cancer risk: genetic polymorphisms alter the preventive effects of cruciferous vegetables
-
Lampe J.W., and Peterson S. Brassica, biotransformation and cancer risk: genetic polymorphisms alter the preventive effects of cruciferous vegetables. J. Nutr. 132 (2002) 2991-2994
-
(2002)
J. Nutr.
, vol.132
, pp. 2991-2994
-
-
Lampe, J.W.1
Peterson, S.2
-
58
-
-
0031711928
-
Urinary total isothiocyanate (itc) in a population-based sample of middle-aged and older hinese in Singapore: relationship with dietary total itc and glutathione s-transferase m1/t1/p1 genotypes
-
Seow A., Shi C.Y., Chung F.L., Jiao D., Hankin J.H., Lee H.P., Coetzee G.A., and Yu M.C. Urinary total isothiocyanate (itc) in a population-based sample of middle-aged and older hinese in Singapore: relationship with dietary total itc and glutathione s-transferase m1/t1/p1 genotypes. Cancer Epidemiol. Biomarkers Prev. 7 (1998) 775-781
-
(1998)
Cancer Epidemiol. Biomarkers Prev.
, vol.7
, pp. 775-781
-
-
Seow, A.1
Shi, C.Y.2
Chung, F.L.3
Jiao, D.4
Hankin, J.H.5
Lee, H.P.6
Coetzee, G.A.7
Yu, M.C.8
-
59
-
-
0036949607
-
Dietary isothiocyanates glutathione s-transferase polymorphisms and colorectal cancer risk in the singapore chinese health study
-
Seow A., Yuan J.M., Sun C.L., Van Den Berg D., Lee H.P., and Yu M.C. Dietary isothiocyanates glutathione s-transferase polymorphisms and colorectal cancer risk in the singapore chinese health study. Carcinogenesis 23 (2002) 2055-2061
-
(2002)
Carcinogenesis
, vol.23
, pp. 2055-2061
-
-
Seow, A.1
Yuan, J.M.2
Sun, C.L.3
Van Den Berg, D.4
Lee, H.P.5
Yu, M.C.6
-
60
-
-
33644688761
-
Glutathione s-transferase m1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli
-
Gasper A.V., Al-Janobi A., Smith J.A., Bacon J.R., Fortun P., Atherton C., Taylor M.A., Hawkey C.J., Barrett D.A., and Mithen R.F. Glutathione s-transferase m1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli. Am. J. Clin. Nutr. 82 (2005) 1283-1291
-
(2005)
Am. J. Clin. Nutr.
, vol.82
, pp. 1283-1291
-
-
Gasper, A.V.1
Al-Janobi, A.2
Smith, J.A.3
Bacon, J.R.4
Fortun, P.5
Atherton, C.6
Taylor, M.A.7
Hawkey, C.J.8
Barrett, D.A.9
Mithen, R.F.10
-
61
-
-
3042688047
-
In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat
-
Hu R., Hebbar V., Kim B.R., Chen C., Winnik B., Buckley B., Soteropoulos P., Tolias P., Hart R.P., and Kong A.N. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. J. Pharmacol. Exp. Ther. 310 (2004) 263-271
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 263-271
-
-
Hu, R.1
Hebbar, V.2
Kim, B.R.3
Chen, C.4
Winnik, B.5
Buckley, B.6
Soteropoulos, P.7
Tolias, P.8
Hart, R.P.9
Kong, A.N.10
-
62
-
-
0036135910
-
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans
-
Ye L., Dinkova-Kostova A.T., Wade K.L., Zhang Y., Shapiro T.A., and Talalay P. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans. Clin Chim. Acta 316 (2002) 43-53
-
(2002)
Clin Chim. Acta
, vol.316
, pp. 43-53
-
-
Ye, L.1
Dinkova-Kostova, A.T.2
Wade, K.L.3
Zhang, Y.4
Shapiro, T.A.5
Talalay, P.6
-
63
-
-
34547795788
-
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
-
Cornblatt B.S., Ye L., Dinkova-Kostova A.T., Erb M., Fahey J.W., Singh N.K., Chen M.-S.A., Stierer T., Garrett-Mayer E., Argani P., Davidson N.E., Talalay P., Kensler T.W., and Visvanathan K. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. Carcinogenesis 28 (2007) 1485-1490
-
(2007)
Carcinogenesis
, vol.28
, pp. 1485-1490
-
-
Cornblatt, B.S.1
Ye, L.2
Dinkova-Kostova, A.T.3
Erb, M.4
Fahey, J.W.5
Singh, N.K.6
Chen, M.-S.A.7
Stierer, T.8
Garrett-Mayer, E.9
Argani, P.10
Davidson, N.E.11
Talalay, P.12
Kensler, T.W.13
Visvanathan, K.14
-
64
-
-
33749581701
-
Cancer chemoprevention of intestinal polyposis in apcmin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable
-
Hu R., Khor T.O., Shen G., Jeong W.S., Hebbar V., Chen C., Xu C., Reddy B., Chada K., and Kong A.N. Cancer chemoprevention of intestinal polyposis in apcmin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable. Carcinogenesis 27 (2006) 2038-2046
-
(2006)
Carcinogenesis
, vol.27
, pp. 2038-2046
-
-
Hu, R.1
Khor, T.O.2
Shen, G.3
Jeong, W.S.4
Hebbar, V.5
Chen, C.6
Xu, C.7
Reddy, B.8
Chada, K.9
Kong, A.N.10
-
65
-
-
0034525122
-
Chemoprevention of colonic aberrant crypt foci in fischer rats by sulforaphane and phenethyl isothiocyanate
-
Chung F.L., Conaway C.C., Rao C.V., and Reddy B.S. Chemoprevention of colonic aberrant crypt foci in fischer rats by sulforaphane and phenethyl isothiocyanate. Carcinogenesis 21 (2000) 2287-2291
-
(2000)
Carcinogenesis
, vol.21
, pp. 2287-2291
-
-
Chung, F.L.1
Conaway, C.C.2
Rao, C.V.3
Reddy, B.S.4
-
66
-
-
33846838750
-
Sulforaphane retards the growth of human pc-3 xenografts and inhibits hdac activity in human subjects
-
Myzak M.C., Tong P., Dashwood W.M., Dashwood R.H., and Ho E. Sulforaphane retards the growth of human pc-3 xenografts and inhibits hdac activity in human subjects. Exp. Biol. Med. (Maywood) 232 (2007) 227-234
-
(2007)
Exp. Biol. Med. (Maywood)
, vol.232
, pp. 227-234
-
-
Myzak, M.C.1
Tong, P.2
Dashwood, W.M.3
Dashwood, R.H.4
Ho, E.5
-
67
-
-
33749165612
-
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase i study
-
Shapiro T.A., Fahey J.W., Dinkova-Kostova A.T., Holtzclaw W.D., Stephenson K.K., Wade K.L., Ye L., and Talalay P. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase i study. Nutr. Cancer 55 (2006) 53-62
-
(2006)
Nutr. Cancer
, vol.55
, pp. 53-62
-
-
Shapiro, T.A.1
Fahey, J.W.2
Dinkova-Kostova, A.T.3
Holtzclaw, W.D.4
Stephenson, K.K.5
Wade, K.L.6
Ye, L.7
Talalay, P.8
-
68
-
-
28644450910
-
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in he zuo township, Qidong, people's republic of china
-
Kensler T.W., Chen J.-G., Egner P.A., Fahey J.W., Jacobson L.P., Stephenson K.K., Ye L., Coady J.L., Wang J.-B., Wu Y., Sun Y., Zhang Q.-N., Zhang B.-C., Zhu Y.-R., Qian G.-S., Carmella S.G., Hecht S.S., Benning L., Gange S.J., Groopman J.D., and Talalay P. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in he zuo township, Qidong, people's republic of china. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 2605-2613
-
(2005)
Cancer Epidemiol. Biomarkers Prev.
, vol.14
, pp. 2605-2613
-
-
Kensler, T.W.1
Chen, J.-G.2
Egner, P.A.3
Fahey, J.W.4
Jacobson, L.P.5
Stephenson, K.K.6
Ye, L.7
Coady, J.L.8
Wang, J.-B.9
Wu, Y.10
Sun, Y.11
Zhang, Q.-N.12
Zhang, B.-C.13
Zhu, Y.-R.14
Qian, G.-S.15
Carmella, S.G.16
Hecht, S.S.17
Benning, L.18
Gange, S.J.19
Groopman, J.D.20
Talalay, P.21
more..
|