Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy

International Journal of Pharmaceutics

Volumn 386, Issue 1-2, 2010, Pages 114-121

  Do, D P ^a   Pai, S B ^b   Rizvi, S A A ^b   D'Souza, M J ^b  

^a LAKE ERIE COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b MERCER UNIVERSITY   (United States)

Author keywords

Albumin; Delivery system; Epigenetic therapy; Histone deacetylase inhibitors; Microspheres; Sulforaphane

Indexed keywords

MICROSPHERE; SULFORAPHANE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; EPIGENETICS; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MELANOMA CELL; MICROENCAPSULATION; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SPRAY DRYING; ZETA POTENTIAL;

ALBUMINS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; EPIGENESIS, GENETIC; HISTONE DEACETYLASE INHIBITORS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSPHERES; PARTICLE SIZE; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; THIOCYANATES; TIME FACTORS; TUMOR BURDEN;

EID: 74149084423     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.11.009     Document Type: Article

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