메뉴 건너뛰기




Volumn 8, Issue , 2017, Pages

Hit and go CAS9 delivered through a lentiviral based self-limiting circuit

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 PROTEIN; DOXYCYCLINE; ENHANCED GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; NUCLEASE; PROTEIN; RNA; TETRACYCLINE; UNCLASSIFIED DRUG;

EID: 85019953441     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15334     Document Type: Article
Times cited : (75)

References (54)
  • 1
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1
  • 2
    • 84876567971 scopus 로고    scopus 로고
    • RNA-programmed genome editing in human cells
    • Jinek, M. et al. RNA-programmed genome editing in human cells. eLife 2, e00471 (2013).
    • (2013) ELife , vol.2 , pp. e00471
    • Jinek, M.1
  • 3
    • 84873734105 scopus 로고    scopus 로고
    • RNA-guided human genome engineering via Cas9
    • Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013).
    • (2013) Science , vol.339 , pp. 823-826
    • Mali, P.1
  • 4
    • 84880570576 scopus 로고    scopus 로고
    • High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
    • Fu, Y. et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 31, 822-826 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 822-826
    • Fu, Y.1
  • 5
    • 84884165315 scopus 로고    scopus 로고
    • DNA targeting specificity of RNA-guided Cas9 nucleases
    • Hsu, P. D. et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 827-832
    • Hsu, P.D.1
  • 6
    • 84925441397 scopus 로고    scopus 로고
    • Determining the specificities of TALENs Cas9 and other genome-editing enzymes
    • Pattanayak, V., Guilinger, J. P. & Liu, D. R. Determining the specificities of TALENs, Cas9, and other genome-editing enzymes. Methods Enzymol. 546, 47-78 (2014).
    • (2014) Methods Enzymol , vol.546 , pp. 47-78
    • Pattanayak, V.1    Guilinger, J.P.2    Liu, D.R.3
  • 7
    • 84923266604 scopus 로고    scopus 로고
    • GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
    • Tsai, S. Q. et al. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187-197 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 187-197
    • Tsai, S.Q.1
  • 8
    • 84923846574 scopus 로고    scopus 로고
    • Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
    • 1 p following 243
    • Kim, D. et al. Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells. Nat. Methods 12, 237-243 1 p following 243 (2015).
    • (2015) Nat. Methods , vol.12
    • Kim, D.1
  • 9
    • 84963940775 scopus 로고    scopus 로고
    • In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
    • Nelson, C. E. et al. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science 351, 403-407 (2016).
    • (2016) Science , vol.351 , pp. 403-407
    • Nelson, C.E.1
  • 10
    • 84888866065 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish
    • Hruscha, A. et al. Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish. Dev. Camb. Engl. 140, 4982-4987 (2013).
    • (2013) Dev. Camb. Engl , vol.140 , pp. 4982-4987
    • Hruscha, A.1
  • 11
    • 84989870879 scopus 로고    scopus 로고
    • A multifunctional AAV-CRISPR-Cas9 and its host response
    • Chew, W. L. et al. A multifunctional AAV-CRISPR-Cas9 and its host response. Nat. Methods 13, 868-874 (2016).
    • (2016) Nat. Methods , vol.13 , pp. 868-874
    • Chew, W.L.1
  • 12
    • 84923106217 scopus 로고    scopus 로고
    • Therapeutic genome editing: Prospects and challenges
    • Cox, D. B. T., Platt, R. J. & Zhang, F. Therapeutic genome editing: prospects and challenges. Nat. Med. 21, 121-131 (2015).
    • (2015) Nat. Med , vol.21 , pp. 121-131
    • Cox, D.B.T.1    Platt, R.J.2    Zhang, F.3
  • 13
    • 84884155038 scopus 로고    scopus 로고
    • High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
    • Pattanayak, V. et al. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. 31, 839-843 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 839-843
    • Pattanayak, V.1
  • 14
    • 84937764361 scopus 로고    scopus 로고
    • Small molecule-triggered Cas9 protein with improved genome-editing specificity
    • Davis, K. M., Pattanayak, V., Thompson, D. B., Zuris, J. A. & Liu, D. R. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat. Chem. Biol. 11, 316-318 (2015).
    • (2015) Nat. Chem. Biol , vol.11 , pp. 316-318
    • Davis, K.M.1    Pattanayak, V.2    Thompson, D.B.3    Zuris, J.A.4    Liu, D.R.5
  • 15
    • 84901834420 scopus 로고    scopus 로고
    • Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
    • Kim, S., Kim, D., Cho, S. W., Kim, J. & Kim, J.-S. Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins. Genome Res. 24, 1012-1019 (2014).
    • (2014) Genome Res , vol.24 , pp. 1012-1019
    • Kim, S.1    Kim, D.2    Cho, S.W.3    Kim, J.4    Kim, J.-S.5
  • 16
    • 84901843996 scopus 로고    scopus 로고
    • Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
    • Ramakrishna, S. et al. Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA. Genome Res. 24, 1020-1027 2014
    • (2014) Genome Res , vol.24 , pp. 1020-1027
    • Ramakrishna, S.1
  • 17
    • 84961288301 scopus 로고    scopus 로고
    • Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
    • Zuris, J. A. et al. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nat. Biotechnol. 33, 73-80 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 73-80
    • Zuris, J.A.1
  • 18
    • 84952943845 scopus 로고    scopus 로고
    • Rationally engineered Cas9 nucleases with improved specificity
    • Slaymaker, I. M. et al. Rationally engineered Cas9 nucleases with improved specificity. Science 351, 84-88 (2016).
    • (2016) Science , vol.351 , pp. 84-88
    • Slaymaker, I.M.1
  • 19
    • 84963941043 scopus 로고    scopus 로고
    • High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
    • Kleinstiver, B. P. et al. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Nature 529, 490-495 (2016).
    • (2016) Nature , vol.529 , pp. 490-495
    • Kleinstiver, B.P.1
  • 20
    • 84949087122 scopus 로고    scopus 로고
    • DNA-binding-domain fusions enhance the targeting range and precision of Cas9
    • Bolukbasi, M. F. et al. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat. Methods 12, 1150-1156 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 1150-1156
    • Bolukbasi, M.F.1
  • 21
    • 84894063115 scopus 로고    scopus 로고
    • Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
    • Chen, B. et al. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 155, 1479-1491 (2013).
    • (2013) Cell , vol.155 , pp. 1479-1491
    • Chen, B.1
  • 22
    • 84887104139 scopus 로고    scopus 로고
    • Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
    • Esvelt, K. M. et al. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat. Methods 10, 1116-1121 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 1116-1121
    • Esvelt, K.M.1
  • 23
    • 84975678715 scopus 로고    scopus 로고
    • Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
    • Zetsche, B. et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell 163, 759-771 (2015).
    • (2015) Cell , vol.163 , pp. 759-771
    • Zetsche, B.1
  • 24
    • 84927514894 scopus 로고    scopus 로고
    • In vivo genome editing using Staphylococcus aureus Cas9
    • Ran, F. A. et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature 520, 186-191 (2015).
    • (2015) Nature , vol.520 , pp. 186-191
    • Ran, F.A.1
  • 25
    • 84917725056 scopus 로고    scopus 로고
    • Easy quantitative assessment of genome editing by sequence trace decomposition
    • Brinkman, E. K., Chen, T., Amendola, M. & van Steensel, B. Easy quantitative assessment of genome editing by sequence trace decomposition. Nucleic Acids Res. 42, e168 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. e168
    • Brinkman, E.K.1    Chen, T.2    Amendola, M.3    Van Steensel, B.4
  • 26
    • 84900314611 scopus 로고    scopus 로고
    • CRISPR-Cas systems for editing, regulating and targeting genomes
    • Sander, J. D. & Joung, J. K. CRISPR-Cas systems for editing, regulating and targeting genomes. Nat. Biotechnol. 32, 347-355 (2014).
    • (2014) Nat. Biotechnol , vol.32 , pp. 347-355
    • Sander, J.D.1    Joung, J.K.2
  • 28
    • 84892765883 scopus 로고    scopus 로고
    • Genome-scale CRISPR-Cas9 knockout screening in human cells
    • Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343, 84-87 (2014).
    • (2014) Science , vol.343 , pp. 84-87
    • Shalem, O.1
  • 29
    • 84987837936 scopus 로고    scopus 로고
    • Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
    • Singh, D., Sternberg, S. H., Fei, J., Doudna, J. A. & Ha, T. Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9. Nat. Commun. 7, 12778 (2016).
    • (2016) Nat. Commun , vol.7 , pp. 12778
    • Singh, D.1    Sternberg, S.H.2    Fei, J.3    Doudna, J.A.4    Ha, T.5
  • 30
    • 84871250204 scopus 로고    scopus 로고
    • Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk
    • Chick, H. E. et al. Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Hum. Gene Ther. 23, 1247-1257 (2012).
    • (2012) Hum. Gene Ther , vol.23 , pp. 1247-1257
    • Chick, H.E.1
  • 31
    • 84947714470 scopus 로고    scopus 로고
    • Characterization of Staphylococcus aureus Cas9: A smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications
    • Friedland, A. E. et al. Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. Genome Biol. 16, 257 (2015).
    • (2015) Genome Biol , vol.16 , pp. 257
    • Friedland, A.E.1
  • 32
    • 84931281543 scopus 로고    scopus 로고
    • AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia
    • Ruozi, G. et al. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nat. Commun. 6, 7388 (2015).
    • (2015) Nat. Commun , vol.6
    • Ruozi, G.1
  • 33
    • 84923275611 scopus 로고    scopus 로고
    • Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
    • Frock, R. L. et al. Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. Nat. Biotechnol. 33, 179-186 2015
    • Nat. Biotechnol , vol.33 , Issue.2015 , pp. 179-186
    • Frock, R.L.1
  • 34
    • 84923096541 scopus 로고    scopus 로고
    • Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
    • Konermann, S. et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature 517, 583-588 (2015).
    • (2015) Nature , vol.517 , pp. 583-588
    • Konermann, S.1
  • 35
    • 84884160273 scopus 로고    scopus 로고
    • CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
    • Mali, P. et al. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 31, 833-838 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 833-838
    • Mali, P.1
  • 36
    • 84929135130 scopus 로고    scopus 로고
    • Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
    • Hilton, I. B. et al. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat. Biotechnol. 33, 510-517 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 510-517
    • Hilton, I.B.1
  • 37
    • 84941057397 scopus 로고    scopus 로고
    • CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells
    • Moore, R. et al. CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells. Nucleic Acids Res. 43, 1297-1303 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. 1297-1303
    • Moore, R.1
  • 38
    • 84946471431 scopus 로고    scopus 로고
    • Cas9 gRNA engineering for genome editing, activation and repression
    • Kiani, S. et al. Cas9 gRNA engineering for genome editing, activation and repression. Nat. Methods 12, 1051-1054 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 1051-1054
    • Kiani, S.1
  • 39
    • 84971299957 scopus 로고    scopus 로고
    • Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
    • Paquet, D. et al. Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9. Nature 533, 125-129 (2016).
    • (2016) Nature , vol.533 , pp. 125-129
    • Paquet, D.1
  • 41
    • 84924322574 scopus 로고    scopus 로고
    • Rational design of a split-Cas9 enzyme complex
    • Wright, A. V. et al. Rational design of a split-Cas9 enzyme complex. Proc. Natl Acad. Sci. USA 112, 2984-2989 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 2984-2989
    • Wright, A.V.1
  • 42
    • 84942793975 scopus 로고    scopus 로고
    • Photoactivatable CRISPR-Cas9 for optogenetic genome editing
    • Nihongaki, Y., Kawano, F., Nakajima, T. & Sato, M. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat. Biotechnol. 33, 755-760 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 755-760
    • Nihongaki, Y.1    Kawano, F.2    Nakajima, T.3    Sato, M.4
  • 43
    • 84923297110 scopus 로고    scopus 로고
    • A split-Cas9 architecture for inducible genome editing and transcription modulation
    • Zetsche, B., Volz, S. E. & Zhang, F. A split-Cas9 architecture for inducible genome editing and transcription modulation. Nat. Biotechnol. 33, 139-142 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 139-142
    • Zetsche, B.1    Volz, S.E.2    Zhang, F.3
  • 44
    • 84960467897 scopus 로고    scopus 로고
    • Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome
    • Muller, M. et al. Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome. Mol. Ther. J. Am. Soc. Gene Ther. 24, 636-644 (2016).
    • (2016) Mol. Ther. J. Am. Soc. Gene Ther , vol.24 , pp. 636-644
    • Muller, M.1
  • 45
    • 84862007841 scopus 로고    scopus 로고
    • Selective targeting of proteins within secretory pathway for endoplasmic reticulum-associated degradation
    • Vecchi, L., Petris, G., Bestagno, M. & Burrone, O. R. Selective targeting of proteins within secretory pathway for endoplasmic reticulum-associated degradation. J. Biol. Chem. 287, 20007-20015 (2012).
    • (2012) J. Biol. Chem , vol.287 , pp. 20007-20015
    • Vecchi, L.1    Petris, G.2    Bestagno, M.3    Burrone, O.R.4
  • 46
    • 84900533377 scopus 로고    scopus 로고
    • New tags for recombinant protein detection and O-glycosylation reporters
    • Petris, G., Bestagno, M., Arnoldi, F. & Burrone, O. R. New tags for recombinant protein detection and O-glycosylation reporters. PLoS ONE 9, e96700 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e96700
    • Petris, G.1    Bestagno, M.2    Arnoldi, F.3    Burrone, O.R.4
  • 47
    • 68449083213 scopus 로고    scopus 로고
    • A versatile viral system for expression and depletion of proteins in mammalian cells
    • Campeau, E. et al. A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS ONE 4, e6529 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e6529
    • Campeau, E.1
  • 48
    • 84905262730 scopus 로고    scopus 로고
    • Improved vectors and genome-wide libraries for CRISPR screening
    • Sanjana, N. E., Shalem, O. & Zhang, F. Improved vectors and genome-wide libraries for CRISPR screening. Nat. Methods 11, 783-784 (2014).
    • (2014) Nat. Methods , vol.11 , pp. 783-784
    • Sanjana, N.E.1    Shalem, O.2    Zhang, F.3
  • 49
    • 84855853673 scopus 로고    scopus 로고
    • Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons
    • Falk, A. et al. Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. PLoS ONE 7, e29597 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e29597
    • Falk, A.1
  • 50
    • 0030822851 scopus 로고    scopus 로고
    • Mammalian cell expression of dimeric small immune proteins (SIP
    • Li, E. et al. Mammalian cell expression of dimeric small immune proteins (SIP). Protein Eng. 10, 731-736 (1997).
    • (1997) Protein Eng , vol.10 , pp. 731-736
    • Li, E.1
  • 51
    • 84922963943 scopus 로고    scopus 로고
    • Reduction of HIV-1 infectivity through endoplasmic reticulum-associated degradationmediated Env depletion
    • Casini, A., Olivieri, M., Vecchi, L., Burrone, O. R. & Cereseto, A. Reduction of HIV-1 infectivity through endoplasmic reticulum-associated degradationmediated Env depletion. J. Virol. 89, 2966-2971 (2015).
    • (2015) J. Virol , vol.89 , pp. 2966-2971
    • Casini, A.1    Olivieri, M.2    Vecchi, L.3    Burrone, O.R.4    Cereseto, A.5
  • 52
    • 84903793743 scopus 로고    scopus 로고
    • Second generation imaging of nuclear/cytoplasmic HIV-1 complexes
    • Francis, A. C. et al. Second generation imaging of nuclear/cytoplasmic HIV-1 complexes. AIDS Res. Hum. Retroviruses 30, 717-726 (2014).
    • (2014) AIDS Res. Hum. Retroviruses , vol.30 , pp. 717-726
    • Francis, A.C.1
  • 53
    • 77949587649 scopus 로고    scopus 로고
    • Fast and accurate long-read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinforma. Oxf. Engl. 26, 589-595 (2010).
    • (2010) Bioinforma. Oxf. Engl , vol.26 , pp. 589-595
    • Li, H.1    Durbin, R.2
  • 54
    • 68549104404 scopus 로고    scopus 로고
    • The sequence alignment/map format and SAMtools
    • Li, H. et al. The sequence alignment/map format and SAMtools. Bioinforma. Oxf. Engl 25, 2078-2079 (2009).
    • (2009) Bioinforma. Oxf. Engl , vol.25 , pp. 2078-2079
    • Li, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.