Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering

ACS Chemical Biology

Volumn 11, Issue 3, 2016, Pages 681-688

  Nuñez, James K ^a   Harrington, Lucas B ^a   Doudna, Jennifer A ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 ENDONUCLEASE; ENDONUCLEASE; INTEIN; RAPAMYCIN; UNCLASSIFIED DRUG; CRISPR ASSOCIATED PROTEIN; PROTEIN BINDING;

CHEMICAL MODIFICATION; COMPLEX FORMATION; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; DIMERIZATION; DNA RECOMBINATION; DNA RNA HYBRIDIZATION; DNA STRAND BREAKAGE; GENE ACTIVATION; GENETIC ENGINEERING; GENETIC REGULATION; GENOME ENGINEERING; GENOMICS; MAMMAL CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OPTOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; REVIEW; RNA SEQUENCE; STATIC ELECTRICITY; TRANSCRIPTION INITIATION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; GENOME; PHYSIOLOGY;

ANIMALS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENOME; PROTEIN BINDING;

EID: 84961782000     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b01019     Document Type: Review

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