-
1
-
-
84962430639
-
Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association
-
COI: 1:CAS:528:DC%2BC28XmtVCiur8%3D, PID: 26404926
-
Insel RA, Dunne JL, Atkinson MA et al (2015) Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care 38:1964–1974
-
(2015)
Diabetes Care
, vol.38
, pp. 1964-1974
-
-
Insel, R.A.1
Dunne, J.L.2
Atkinson, M.A.3
-
2
-
-
84939961476
-
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
-
COI: 1:CAS:528:DC%2BC2MXislGrsr4%3D, PID: 25660258
-
Krischer JP, Lynch KF, Schatz DA et al (2015) The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study. Diabetologia 58:980–987
-
(2015)
Diabetologia
, vol.58
, pp. 980-987
-
-
Krischer, J.P.1
Lynch, K.F.2
Schatz, D.A.3
-
3
-
-
84891542721
-
Patterns of β-cell autoantibody appearance and genetic associations during the first years of life
-
COI: 1:CAS:528:DC%2BC3sXhsFOhtLnO, PID: 23835325
-
Ilonen J, Hammais A, Laine AP et al (2013) Patterns of β-cell autoantibody appearance and genetic associations during the first years of life. Diabetes 62:3636–3640
-
(2013)
Diabetes
, vol.62
, pp. 3636-3640
-
-
Ilonen, J.1
Hammais, A.2
Laine, A.P.3
-
4
-
-
0033016840
-
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study
-
COI: 1:STN:280:DyaK1M7ns1Cgsg%3D%3D, PID: 10078544
-
Ziegler AG, Hummel M, Schenker M, Bonifacio E (1999) Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. Diabetes 48:460–468
-
(1999)
Diabetes
, vol.48
, pp. 460-468
-
-
Ziegler, A.G.1
Hummel, M.2
Schenker, M.3
Bonifacio, E.4
-
5
-
-
0022389143
-
The epidemiology of diabetes in Swedish children 0-14 years—a six-year prospective study
-
COI: 1:STN:280:DyaL287gvFajug%3D%3D, PID: 3878809
-
Dahlquist G, Blom L, Holmgren G et al (1985) The epidemiology of diabetes in Swedish children 0-14 years—a six-year prospective study. Diabetologia 28:802–808
-
(1985)
Diabetologia
, vol.28
, pp. 802-808
-
-
Dahlquist, G.1
Blom, L.2
Holmgren, G.3
-
6
-
-
84975920751
-
Genetic risk factors for type 1 diabetes
-
COI: 1:CAS:528:DC%2BC28Xps1yqt7s%3D, PID: 27302272
-
Pociot F, Lernmark A (2016) Genetic risk factors for type 1 diabetes. Lancet 387:2331–2339
-
(2016)
Lancet
, vol.387
, pp. 2331-2339
-
-
Pociot, F.1
Lernmark, A.2
-
7
-
-
7444253875
-
IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes
-
PID: 15505007
-
Bonifacio E, Hummel M, Walter M, Schmid S, Ziegler AG (2004) IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes. Diabetes Care 27:2695–2700
-
(2004)
Diabetes Care
, vol.27
, pp. 2695-2700
-
-
Bonifacio, E.1
Hummel, M.2
Walter, M.3
Schmid, S.4
Ziegler, A.G.5
-
8
-
-
0345505676
-
Genetic liability of type 1 diabetes and the onset age among 22, 650 young Finnish twin pairs: a nationwide follow-up study
-
COI: 1:CAS:528:DC%2BD3sXislOnsLo%3D, PID: 12663480
-
Hyttinen V, Kaprio J, Kinnunen L, Koskenvuo M, Tuomilehto J (2003) Genetic liability of type 1 diabetes and the onset age among 22, 650 young Finnish twin pairs: a nationwide follow-up study. Diabetes 52:1052–1055
-
(2003)
Diabetes
, vol.52
, pp. 1052-1055
-
-
Hyttinen, V.1
Kaprio, J.2
Kinnunen, L.3
Koskenvuo, M.4
Tuomilehto, J.5
-
9
-
-
84924966095
-
Epigenomics of autoimmune diseases
-
COI: 1:CAS:528:DC%2BC2MXkvVyitbc%3D, PID: 25776989
-
Gupta B, Hawkins RD (2015) Epigenomics of autoimmune diseases. Immunol Cell Biol 93:271–276
-
(2015)
Immunol Cell Biol
, vol.93
, pp. 271-276
-
-
Gupta, B.1
Hawkins, R.D.2
-
10
-
-
84860484176
-
Overview of the type I diabetes genetics consortium
-
PID: 19956093
-
Rich SS, Akolkar B, Concannon P et al (2009) Overview of the type I diabetes genetics consortium. Genes Immun 10(Suppl 1):S1–S4
-
(2009)
Genes Immun
, vol.10
, pp. S1-S4
-
-
Rich, S.S.1
Akolkar, B.2
Concannon, P.3
-
11
-
-
84981556018
-
Role of type 1 diabetes-associated SNPs on risk of autoantibody positivity in the TEDDY study
-
PID: 25422107
-
Torn C, Hadley D, Lee HS et al (2015) Role of type 1 diabetes-associated SNPs on risk of autoantibody positivity in the TEDDY study. Diabetes 64:1818–1829
-
(2015)
Diabetes
, vol.64
, pp. 1818-1829
-
-
Torn, C.1
Hadley, D.2
Lee, H.S.3
-
12
-
-
84884311983
-
Major histocompatibility complex genomics and human disease
-
COI: 1:CAS:528:DC%2BC3sXhslSmsrnN, PID: 23875801
-
Trowsdale J, Knight JC (2013) Major histocompatibility complex genomics and human disease. Annu Rev Genomics Hum Genet 14:301–323
-
(2013)
Annu Rev Genomics Hum Genet
, vol.14
, pp. 301-323
-
-
Trowsdale, J.1
Knight, J.C.2
-
13
-
-
0029953008
-
The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families
-
COI: 1:CAS:528:DyaK28XmvFyks7c%3D, PID: 8900244
-
Noble JA, Valdes AM, Cook M, Klitz W, Thomson G, Erlich HA (1996) The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet 59:1134–1148
-
(1996)
Am J Hum Genet
, vol.59
, pp. 1134-1148
-
-
Noble, J.A.1
Valdes, A.M.2
Cook, M.3
Klitz, W.4
Thomson, G.5
Erlich, H.A.6
-
14
-
-
84878240572
-
Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms
-
COI: 1:CAS:528:DC%2BC3sXpt1Orsbg%3D, PID: 23378606
-
Nguyen C, Varney MD, Harrison LC, Morahan G (2013) Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms. Diabetes 62:2135–2140
-
(2013)
Diabetes
, vol.62
, pp. 2135-2140
-
-
Nguyen, C.1
Varney, M.D.2
Harrison, L.C.3
Morahan, G.4
-
15
-
-
34347389454
-
Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis
-
COI: 1:CAS:528:DC%2BD2sXpsVGiu7g%3D, PID: 17610416
-
Thomson G, Valdes AM, Noble JA et al (2007) Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens 70:110–127
-
(2007)
Tissue Antigens
, vol.70
, pp. 110-127
-
-
Thomson, G.1
Valdes, A.M.2
Noble, J.A.3
-
16
-
-
0028584260
-
Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives
-
COI: 1:STN:280:DyaK2M%2FhtFSksA%3D%3D, PID: 7926304
-
Bingley PJ, Christie MR, Bonifacio E et al (1994) Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes 43:1304–1310
-
(1994)
Diabetes
, vol.43
, pp. 1304-1310
-
-
Bingley, P.J.1
Christie, M.R.2
Bonifacio, E.3
-
17
-
-
0037898334
-
Multiple autoantibodies as predictors of type 1 diabetes in a general population
-
COI: 1:STN:280:DC%2BD3szgslWisA%3D%3D, PID: 12802500
-
Maclaren NK, Lan MS, Schatz D, Malone J, Notkins AL, Krischer J (2003) Multiple autoantibodies as predictors of type 1 diabetes in a general population. Diabetologia 46:873–874
-
(2003)
Diabetologia
, vol.46
, pp. 873-874
-
-
Maclaren, N.K.1
Lan, M.S.2
Schatz, D.3
Malone, J.4
Notkins, A.L.5
Krischer, J.6
-
18
-
-
84879114358
-
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children
-
COI: 1:CAS:528:DC%2BC3sXhtFCrsLnL, PID: 23780460
-
Ziegler AG, Rewers M, Simell O et al (2013) Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 309:2473–2479
-
(2013)
JAMA
, vol.309
, pp. 2473-2479
-
-
Ziegler, A.G.1
Rewers, M.2
Simell, O.3
-
19
-
-
77949273351
-
Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2β) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: implications for prevention trials
-
COI: 1:CAS:528:DC%2BC3cXhsVygtro%3D, PID: 20091020
-
De Grijse J, Asanghanwa M, Nouthe B et al (2010) Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2β) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: implications for prevention trials. Diabetologia 53:517–524
-
(2010)
Diabetologia
, vol.53
, pp. 517-524
-
-
De Grijse, J.1
Asanghanwa, M.2
Nouthe, B.3
-
20
-
-
84861761425
-
Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies
-
COI: 1:CAS:528:DC%2BC38Xps1Kit7s%3D, PID: 22446173
-
Yu L, Boulware DC, Beam CA et al (2012) Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care 35:1213–1218
-
(2012)
Diabetes Care
, vol.35
, pp. 1213-1218
-
-
Yu, L.1
Boulware, D.C.2
Beam, C.A.3
-
21
-
-
0036319041
-
Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes
-
COI: 1:CAS:528:DC%2BD38XjtlGmtrc%3D, PID: 11978629
-
Graham J, Hagopian WA, Kockum I et al (2002) Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 51:1346–1355
-
(2002)
Diabetes
, vol.51
, pp. 1346-1355
-
-
Graham, J.1
Hagopian, W.A.2
Kockum, I.3
-
22
-
-
0036078122
-
Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes
-
PID: 12116176
-
Knip M, Kukko M, Kulmala P et al (2002) Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes. Am J Med Genet 115:48–54
-
(2002)
Am J Med Genet
, vol.115
, pp. 48-54
-
-
Knip, M.1
Kukko, M.2
Kulmala, P.3
-
23
-
-
79960140955
-
The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3MXos1Kju7c%3D, PID: 21244337
-
Andersson C, Larsson K, Vaziri-Sani F et al (2011) The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes. Autoimmunity 44:394–405
-
(2011)
Autoimmunity
, vol.44
, pp. 394-405
-
-
Andersson, C.1
Larsson, K.2
Vaziri-Sani, F.3
-
24
-
-
84866596750
-
Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study
-
COI: 1:CAS:528:DC%2BC38XhsVentL%2FE, PID: 22787139
-
Delli AJ, Vaziri-Sani F, Lindblad B et al (2012) Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study. Diabetes 61:2556–2564
-
(2012)
Diabetes
, vol.61
, pp. 2556-2564
-
-
Delli, A.J.1
Vaziri-Sani, F.2
Lindblad, B.3
-
25
-
-
42449144715
-
HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families
-
COI: 1:CAS:528:DC%2BD1cXksVGrsr4%3D, PID: 18252895
-
Erlich H, Valdes AM, Noble J et al (2008) HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. Diabetes 57:1084–1092
-
(2008)
Diabetes
, vol.57
, pp. 1084-1092
-
-
Erlich, H.1
Valdes, A.M.2
Noble, J.3
-
26
-
-
4143139832
-
Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom
-
COI: 1:CAS:528:DC%2BD2cXmslKlsr4%3D, PID: 15292346
-
Lambert AP, Gillespie KM, Thomson G et al (2004) Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom. J Clin Endocrinol Metab 89:4037–4043
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4037-4043
-
-
Lambert, A.P.1
Gillespie, K.M.2
Thomson, G.3
-
27
-
-
34249892413
-
Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations
-
COI: 1:CAS:528:DC%2BD2sXksVCjtLk%3D, PID: 17473382
-
Laine AP, Holmberg H, Nilsson A et al (2007) Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations. Dis Markers 23:139–145
-
(2007)
Dis Markers
, vol.23
, pp. 139-145
-
-
Laine, A.P.1
Holmberg, H.2
Nilsson, A.3
-
28
-
-
84959114986
-
An integrated genotyping approach for HLA and other complex genetic systems
-
COI: 1:CAS:528:DC%2BC2MXpt1ymtro%3D, PID: 26027777
-
Nelson WC, Pyo CW, Vogan D et al (2015) An integrated genotyping approach for HLA and other complex genetic systems. Hum Immunol 76:928–938
-
(2015)
Hum Immunol
, vol.76
, pp. 928-938
-
-
Nelson, W.C.1
Pyo, C.W.2
Vogan, D.3
-
29
-
-
84908011842
-
Next generation sequencing to determine HLA class II genotypes in a cohort of hematopoietic cell transplant patients and donors
-
COI: 1:CAS:528:DC%2BC2cXhsVyht7fE, PID: 25167774
-
Smith AG, Pyo CW, Nelson W et al (2014) Next generation sequencing to determine HLA class II genotypes in a cohort of hematopoietic cell transplant patients and donors. Hum Immunol 75:1040–1046
-
(2014)
Hum Immunol
, vol.75
, pp. 1040-1046
-
-
Smith, A.G.1
Pyo, C.W.2
Nelson, W.3
-
30
-
-
84962440475
-
Next-generation sequencing reveals that HLA-DRB3, -DRB4, and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes
-
COI: 1:CAS:528:DC%2BC28XhtFamsb7I, PID: 26740600
-
Zhao LP, Alshiekh S, Zhao M et al (2016) Next-generation sequencing reveals that HLA-DRB3, -DRB4, and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes. Diabetes 65:710–718
-
(2016)
Diabetes
, vol.65
, pp. 710-718
-
-
Zhao, L.P.1
Alshiekh, S.2
Zhao, M.3
-
31
-
-
84879551555
-
Next generation sequencing reveals the association of DRB3*02:02 with type I diabetes
-
COI: 1:CAS:528:DC%2BC3sXhtFWjsbzL, PID: 23462545
-
Erlich HA, Valdes AM, McDevitt S et al (2013) Next generation sequencing reveals the association of DRB3*02:02 with type I diabetes. Diabetes 62:2618–2622
-
(2013)
Diabetes
, vol.62
, pp. 2618-2622
-
-
Erlich, H.A.1
Valdes, A.M.2
McDevitt, S.3
-
32
-
-
28444477379
-
D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BD2MXht1Omu7zP, PID: 16320082
-
Valdes AM, Thomson G, Graham J et al (2005) D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus. Diabetologia 48:2540–2543
-
(2005)
Diabetologia
, vol.48
, pp. 2540-2543
-
-
Valdes, A.M.1
Thomson, G.2
Graham, J.3
-
33
-
-
78049246370
-
HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium
-
COI: 1:CAS:528:DC%2BC3cXhsV2nsb3P, PID: 20798335
-
Noble JA, Valdes AM, Varney MD et al (2010) HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. Diabetes 59:2972–2979
-
(2010)
Diabetes
, vol.59
, pp. 2972-2979
-
-
Noble, J.A.1
Valdes, A.M.2
Varney, M.D.3
-
35
-
-
77951499981
-
Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes
-
COI: 1:CAS:528:DC%2BC3cXkvFCqsrk%3D, PID: 20054343
-
Valdes AM, Thomson G, Barcellos LF (2010) Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes. Genes Immun 11:209–218
-
(2010)
Genes Immun
, vol.11
, pp. 209-218
-
-
Valdes, A.M.1
Thomson, G.2
Barcellos, L.F.3
-
36
-
-
84975091581
-
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study
-
Torn C, Liu X, Hagopian W et al (2016) Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study. Sci Report 6:27887
-
(2016)
Sci Report
, vol.6
, pp. 27887
-
-
Torn, C.1
Liu, X.2
Hagopian, W.3
-
37
-
-
84949107978
-
Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies
-
COI: 1:CAS:528:DC%2BC2MXhslCqtbfK, PID: 26513234
-
Maziarz M, Hagopian W, Palmer JP et al (2015) Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies. Genes Immun 16:541–551
-
(2015)
Genes Immun
, vol.16
, pp. 541-551
-
-
Maziarz, M.1
Hagopian, W.2
Palmer, J.P.3
-
38
-
-
84859526125
-
Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression
-
COI: 1:CAS:528:DC%2BC38XkslCht7c%3D, PID: 22344559
-
Bergholdt R, Brorsson C, Palleja A et al (2012) Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression. Diabetes 61:954–962
-
(2012)
Diabetes
, vol.61
, pp. 954-962
-
-
Bergholdt, R.1
Brorsson, C.2
Palleja, A.3
-
39
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
COI: 1:CAS:528:DC%2BD3sXktVygtLk%3D, PID: 12724780
-
Ueda H, Howson JM, Esposito L et al (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423:506–511
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
-
40
-
-
77954288805
-
Genetics of type 1 diabetes: what's next?
-
COI: 1:CAS:528:DC%2BC3cXpsVOmu7g%3D, PID: 20587799
-
Pociot F, Akolkar B, Concannon P et al (2010) Genetics of type 1 diabetes: what's next? Diabetes 59:1561–1571
-
(2010)
Diabetes
, vol.59
, pp. 1561-1571
-
-
Pociot, F.1
Akolkar, B.2
Concannon, P.3
-
41
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
COI: 1:CAS:528:DC%2BC3MXhtFCktbzM, PID: 21852963
-
Cotsapas C, Voight BF, Rossin E et al (2011) Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet 7:e1002254
-
(2011)
PLoS Genet
, vol.7
-
-
Cotsapas, C.1
Voight, B.F.2
Rossin, E.3
-
42
-
-
84882449068
-
Genetic insights into common pathways and complex relationships among immune-mediated diseases
-
COI: 1:CAS:528:DC%2BC3sXht1WrtLfJ, PID: 23917628
-
Parkes M, Cortes A, van Heel DA, Brown MA (2013) Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet 14:661–673
-
(2013)
Nat Rev Genet
, vol.14
, pp. 661-673
-
-
Parkes, M.1
Cortes, A.2
van Heel, D.A.3
Brown, M.A.4
-
43
-
-
14644445981
-
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
-
COI: 1:CAS:528:DC%2BD2MXitlegsbo%3D, PID: 15734872
-
Zheng W, She JX (2005) Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes. Diabetes 54:906–908
-
(2005)
Diabetes
, vol.54
, pp. 906-908
-
-
Zheng, W.1
She, J.X.2
-
44
-
-
41149154285
-
Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes
-
COI: 1:CAS:528:DC%2BD1cXjsFGiurg%3D, PID: 18292987
-
Bjornvold M, Undlien DE, Joner G et al (2008) Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes. Diabetologia 51:589–596
-
(2008)
Diabetologia
, vol.51
, pp. 589-596
-
-
Bjornvold, M.1
Undlien, D.E.2
Joner, G.3
-
45
-
-
84975922069
-
Environmental risk factors for type 1 diabetes
-
COI: 1:CAS:528:DC%2BC28Xps1yqt7o%3D, PID: 27302273
-
Rewers M, Ludvigsson J (2016) Environmental risk factors for type 1 diabetes. Lancet 387:2340–2348
-
(2016)
Lancet
, vol.387
, pp. 2340-2348
-
-
Rewers, M.1
Ludvigsson, J.2
-
46
-
-
78649762200
-
Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies
-
PID: 20337975
-
Delli AJ, Lindblad B, Carlsson A et al (2010) Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies. Pediatr Diabetes 11:513–520
-
(2010)
Pediatr Diabetes
, vol.11
, pp. 513-520
-
-
Delli, A.J.1
Lindblad, B.2
Carlsson, A.3
-
47
-
-
0033808399
-
Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group
-
COI: 1:STN:280:DC%2BD3cvmvVaqtA%3D%3D, PID: 11023146
-
Karvonen M, Viik-Kajander M, Moltchanova E, Libman I, LaPorte R, Tuomilehto J (2000) Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group. Diabetes Care 23:1516–1526
-
(2000)
Diabetes Care
, vol.23
, pp. 1516-1526
-
-
Karvonen, M.1
Viik-Kajander, M.2
Moltchanova, E.3
Libman, I.4
LaPorte, R.5
Tuomilehto, J.6
-
48
-
-
84919418302
-
Rapidly rising incidence of childhood type 1 diabetes in Chinese population: epidemiology in Shanghai during 1997-2011
-
PID: 24777734
-
Zhao Z, Sun C, Wang C et al (2014) Rapidly rising incidence of childhood type 1 diabetes in Chinese population: epidemiology in Shanghai during 1997-2011. Acta Diabetol 51:947–953
-
(2014)
Acta Diabetol
, vol.51
, pp. 947-953
-
-
Zhao, Z.1
Sun, C.2
Wang, C.3
-
49
-
-
79551607451
-
Thirty years of prospective nationwide incidence of childhood type 1 diabetes: the accelerating increase by time tends to level off in Sweden
-
COI: 1:CAS:528:DC%2BC3MXisVOmu7o%3D, PID: 21270269
-
Berhan Y, Waernbaum I, Lind T, Mollsten A, Dahlquist G, Swedish Childhood Diabetes Study G (2011) Thirty years of prospective nationwide incidence of childhood type 1 diabetes: the accelerating increase by time tends to level off in Sweden. Diabetes 60:577–581
-
(2011)
Diabetes
, vol.60
, pp. 577-581
-
-
Berhan, Y.1
Waernbaum, I.2
Lind, T.3
Mollsten, A.4
Dahlquist, G.5
-
50
-
-
84906822167
-
ISPAD Clinical Practice Consensus Guidelines 2014. Phases of type 1 diabetes in children and adolescents
-
COI: 1:CAS:528:DC%2BC2cXhsV2qt7rK, PID: 25325095
-
Couper JJ, Haller MJ, Ziegler AG et al (2014) ISPAD Clinical Practice Consensus Guidelines 2014. Phases of type 1 diabetes in children and adolescents. Pediatr Diabetes 15(Suppl 20):18–25
-
(2014)
Pediatr Diabetes
, vol.15
, pp. 18-25
-
-
Couper, J.J.1
Haller, M.J.2
Ziegler, A.G.3
-
51
-
-
78650552840
-
Protection against or triggering of type 1 diabetes? Different roles for viral infections
-
COI: 1:CAS:528:DC%2BC3cXhsFOgtL3M, PID: 21162649
-
Boettler T, von Herrath M (2011) Protection against or triggering of type 1 diabetes? Different roles for viral infections. Expert Rev Clin Immunol 7:45–53
-
(2011)
Expert Rev Clin Immunol
, vol.7
, pp. 45-53
-
-
Boettler, T.1
von Herrath, M.2
-
52
-
-
49249094939
-
Congenital rubella: citation virus or viral cause of type 1 diabetes?
-
COI: 1:STN:280:DC%2BD1cvpvFWlsA%3D%3D, PID: 18641967
-
Gale EA (2008) Congenital rubella: citation virus or viral cause of type 1 diabetes? Diabetologia 51:1559–1566
-
(2008)
Diabetologia
, vol.51
, pp. 1559-1566
-
-
Gale, E.A.1
-
53
-
-
84865010272
-
Seroconversion to islet autoantibodies after enterovirus infection in early pregnancy
-
COI: 1:CAS:528:DC%2BC38XhtFKjurjO, PID: 22746839
-
Resic Lindehammer S, Honkanen H, Nix WA et al (2012) Seroconversion to islet autoantibodies after enterovirus infection in early pregnancy. Viral Immunol 25:254–261
-
(2012)
Viral Immunol
, vol.25
, pp. 254-261
-
-
Resic Lindehammer, S.1
Honkanen, H.2
Nix, W.A.3
-
54
-
-
20244384697
-
A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM
-
COI: 1:STN:280:DyaK2MzgvFGhtQ%3D%3D
-
Hyoty H, Hiltunen M, Knip M et al (1995) A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Child Diabetes Finl (DiMe) Study Group Diabetes 44:652–657
-
(1995)
Child Diabetes Finl (DiMe) Study Group Diabetes
, vol.44
, pp. 652-657
-
-
Hyoty, H.1
Hiltunen, M.2
Knip, M.3
-
55
-
-
0028791239
-
Indications that maternal coxsackie B virus infection during pregnancy is a risk factor for childhood-onset IDDM
-
COI: 1:STN:280:DyaK287kslShsQ%3D%3D, PID: 8582549
-
Dahlquist G, Frisk G, Ivarsson SA, Svanberg L, Forsgren M, Diderholm H (1995) Indications that maternal coxsackie B virus infection during pregnancy is a risk factor for childhood-onset IDDM. Diabetologia 38:1371–1373
-
(1995)
Diabetologia
, vol.38
, pp. 1371-1373
-
-
Dahlquist, G.1
Frisk, G.2
Ivarsson, S.A.3
Svanberg, L.4
Forsgren, M.5
Diderholm, H.6
-
56
-
-
84921565447
-
The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young
-
COI: 1:CAS:528:DC%2BC2MXhsF2lsb8%3D, PID: 24444005
-
Lamb MM, Miller M, Seifert JA et al (2015) The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young. Pediatr Diabetes 16:31–38
-
(2015)
Pediatr Diabetes
, vol.16
, pp. 31-38
-
-
Lamb, M.M.1
Miller, M.2
Seifert, J.A.3
-
57
-
-
84902209257
-
Hydrolyzed infant formula and early beta-cell autoimmunity: a randomized clinical trial
-
PID: 24915259
-
Knip M, Akerblom HK, Becker D et al (2014) Hydrolyzed infant formula and early beta-cell autoimmunity: a randomized clinical trial. JAMA 311:2279–2287
-
(2014)
JAMA
, vol.311
, pp. 2279-2287
-
-
Knip, M.1
Akerblom, H.K.2
Becker, D.3
-
58
-
-
84863730742
-
Serum long chain n-3 fatty acids (EPA and DHA) in the pregnant mother are independent of risk of type 1 diabetes in the offspring
-
COI: 1:CAS:528:DC%2BC38XpvVegtr8%3D, PID: 22396195
-
Sorensen IM, Joner G, Jenum PA, Eskild A, Stene LC (2012) Serum long chain n-3 fatty acids (EPA and DHA) in the pregnant mother are independent of risk of type 1 diabetes in the offspring. Diabetes Metab Res Rev 28:431–438
-
(2012)
Diabetes Metab Res Rev
, vol.28
, pp. 431-438
-
-
Sorensen, I.M.1
Joner, G.2
Jenum, P.A.3
Eskild, A.4
Stene, L.C.5
-
59
-
-
84954121518
-
Association of early exposure of probiotics and islet autoimmunity in the TEDDY study
-
PID: 26552054
-
Uusitalo U, Liu X, Yang J et al (2016) Association of early exposure of probiotics and islet autoimmunity in the TEDDY study. JAMA Pediatr 170:20–28
-
(2016)
JAMA Pediatr
, vol.170
, pp. 20-28
-
-
Uusitalo, U.1
Liu, X.2
Yang, J.3
-
60
-
-
31444447456
-
Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis
-
COI: 1:STN:280:DC%2BD28%2FltVGhsA%3D%3D, PID: 16362279
-
Dahlquist G (2006) Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis. Diabetologia 49:20–24
-
(2006)
Diabetologia
, vol.49
, pp. 20-24
-
-
Dahlquist, G.1
-
61
-
-
84938741189
-
Sugar intake is associated with progression from islet autoimmunity to type 1 diabetes: the Diabetes Autoimmunity Study in the Young
-
COI: 1:CAS:528:DC%2BC2MXhtVegsL7J, PID: 26048237
-
Lamb MM, Frederiksen B, Seifert JA, Kroehl M, Rewers M, Norris JM (2015) Sugar intake is associated with progression from islet autoimmunity to type 1 diabetes: the Diabetes Autoimmunity Study in the Young. Diabetologia 58:2027–2034
-
(2015)
Diabetologia
, vol.58
, pp. 2027-2034
-
-
Lamb, M.M.1
Frederiksen, B.2
Seifert, J.A.3
Kroehl, M.4
Rewers, M.5
Norris, J.M.6
-
62
-
-
84872708324
-
Primary and secondary prevention of type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXjt1eluro%3D, PID: 23231526
-
Skyler JS (2013) Primary and secondary prevention of type 1 diabetes. Diabet Med 30:161–169
-
(2013)
Diabet Med
, vol.30
, pp. 161-169
-
-
Skyler, J.S.1
-
63
-
-
75149163252
-
Clinical applications of diabetes antibody testing
-
COI: 1:CAS:528:DC%2BC3cXhtVGhsrw%3D, PID: 19875480
-
Bingley PJ (2010) Clinical applications of diabetes antibody testing. J Clin Endocrinol Metab 95:25–33
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 25-33
-
-
Bingley, P.J.1
-
64
-
-
84904537945
-
Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies
-
PID: 24206368
-
Andersson C, Kolmodin M, Ivarsson SA et al (2013) Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies. Pediatr Diabetes 15:336–344
-
(2013)
Pediatr Diabetes
, vol.15
, pp. 336-344
-
-
Andersson, C.1
Kolmodin, M.2
Ivarsson, S.A.3
-
65
-
-
84884589209
-
Novel diabetes autoantibodies and prediction of type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhsVOgtrvE, PID: 23900975
-
Wenzlau JM, Hutton JC (2013) Novel diabetes autoantibodies and prediction of type 1 diabetes. Curr Diab Rep 13:608–615
-
(2013)
Curr Diab Rep
, vol.13
, pp. 608-615
-
-
Wenzlau, J.M.1
Hutton, J.C.2
-
66
-
-
84975263470
-
Predictors of slow progression to diabetes in children with multiple islet autoantibodies
-
COI: 1:CAS:528:DC%2BC28XptFequr4%3D, PID: 27255734
-
Steck AK, Dong F, Waugh K et al (2016) Predictors of slow progression to diabetes in children with multiple islet autoantibodies. J Autoimmun 72:113–117
-
(2016)
J Autoimmun
, vol.72
, pp. 113-117
-
-
Steck, A.K.1
Dong, F.2
Waugh, K.3
-
67
-
-
80051979794
-
Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young
-
PID: 21562325
-
Steck AK, Johnson KJ, Barriga D et al (2011) Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young. Diabetes Care 34:1397–1399
-
(2011)
Diabetes Care
, vol.34
, pp. 1397-1399
-
-
Steck, A.K.1
Johnson, K.J.2
Barriga, D.3
-
68
-
-
84978120392
-
A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children
-
COI: 1:CAS:528:DC%2BC28XhtFOhu7nI, PID: 27400691
-
Endesfelder D, Hagen M, Winkler C et al (2016) A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children. Diabetologia 59:2172–2180
-
(2016)
Diabetologia
, vol.59
, pp. 2172-2180
-
-
Endesfelder, D.1
Hagen, M.2
Winkler, C.3
-
69
-
-
84928811876
-
Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY)
-
PID: 25665818
-
Steck AK, Vehik K, Bonifacio E et al (2015) Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care 38:808–813
-
(2015)
Diabetes Care
, vol.38
, pp. 808-813
-
-
Steck, A.K.1
Vehik, K.2
Bonifacio, E.3
-
70
-
-
0036460367
-
IA-2 autoantibodies predict impending type I diabetes in siblings of patients
-
COI: 1:CAS:528:DC%2BD38XpsFOmsL4%3D, PID: 12488955
-
Decochez K, De Leeuw IH, Keymeulen B et al (2002) IA-2 autoantibodies predict impending type I diabetes in siblings of patients. Diabetologia 45:1658–1666
-
(2002)
Diabetologia
, vol.45
, pp. 1658-1666
-
-
Decochez, K.1
De Leeuw, I.H.2
Keymeulen, B.3
-
71
-
-
84870442527
-
Screening for insulinoma antigen 2 and zinc transporter 8 autoantibodies: a cost-effective and age-independent strategy to identify rapid progressors to clinical onset among relatives of type 1 diabetic patients
-
COI: 1:CAS:528:DC%2BC38XhslKrtL3F, PID: 23199327
-
Gorus FK, Balti EV, Vermeulen I et al (2013) Screening for insulinoma antigen 2 and zinc transporter 8 autoantibodies: a cost-effective and age-independent strategy to identify rapid progressors to clinical onset among relatives of type 1 diabetic patients. Clin Exp Immunol 171:82–90
-
(2013)
Clin Exp Immunol
, vol.171
, pp. 82-90
-
-
Gorus, F.K.1
Balti, E.V.2
Vermeulen, I.3
-
72
-
-
84986211384
-
Reversion of beta-cell autoimmunity changes risk of type 1 diabetes: TEDDY study
-
PID: 27311490
-
Vehik K, Lynch KF, Schatz DA et al (2016) Reversion of beta-cell autoimmunity changes risk of type 1 diabetes: TEDDY study. Diabetes Care 39:1535–1542
-
(2016)
Diabetes Care
, vol.39
, pp. 1535-1542
-
-
Vehik, K.1
Lynch, K.F.2
Schatz, D.A.3
-
73
-
-
77956089036
-
Prediction of type 1 diabetes in the general population
-
PID: 20508230
-
Knip M, Korhonen S, Kulmala P et al (2010) Prediction of type 1 diabetes in the general population. Diabetes Care 33:1206–1212
-
(2010)
Diabetes Care
, vol.33
, pp. 1206-1212
-
-
Knip, M.1
Korhonen, S.2
Kulmala, P.3
-
74
-
-
84951022849
-
Predicting type 1 diabetes using biomarkers
-
COI: 1:CAS:528:DC%2BC2MXhtFymsrrI, PID: 25998291
-
Bonifacio E (2015) Predicting type 1 diabetes using biomarkers. Diabetes Care 38:989–996
-
(2015)
Diabetes Care
, vol.38
, pp. 989-996
-
-
Bonifacio, E.1
-
75
-
-
20944431720
-
Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes
-
COI: 1:CAS:528:DC%2BD2MXjtlGhs7g%3D, PID: 15756536
-
Decochez K, Truyen I, van der Auwera B et al (2005) Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes. Diabetologia 48:687–694
-
(2005)
Diabetologia
, vol.48
, pp. 687-694
-
-
Decochez, K.1
Truyen, I.2
van der Auwera, B.3
-
76
-
-
84878847275
-
Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children
-
COI: 1:CAS:528:DC%2BC3sXptVCntLY%3D, PID: 23539116
-
Achenbach P, Hummel M, Thumer L, Boerschmann H, Hofelmann D, Ziegler AG (2013) Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children. Diabetologia 56:1615–1622
-
(2013)
Diabetologia
, vol.56
, pp. 1615-1622
-
-
Achenbach, P.1
Hummel, M.2
Thumer, L.3
Boerschmann, H.4
Hofelmann, D.5
Ziegler, A.G.6
-
77
-
-
84945967120
-
Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies
-
COI: 1:CAS:528:DC%2BC2MXhvVSlsL7K, PID: 26313035
-
Wiberg A, Granstam A, Ingvast S et al (2015) Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies. Clin Exp Immunol 182:278–288
-
(2015)
Clin Exp Immunol
, vol.182
, pp. 278-288
-
-
Wiberg, A.1
Granstam, A.2
Ingvast, S.3
-
78
-
-
84962422694
-
Insulitis and β-cell mass in the natural history of type 1 diabetes
-
COI: 1:CAS:528:DC%2BC28XhtVKltLfM, PID: 26581594
-
Campbell-Thompson M, Fu A, Kaddis JS et al (2016) Insulitis and β-cell mass in the natural history of type 1 diabetes. Diabetes 65:719–731
-
(2016)
Diabetes
, vol.65
, pp. 719-731
-
-
Campbell-Thompson, M.1
Fu, A.2
Kaddis, J.S.3
-
79
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
PID: 21248163
-
van Belle TL, Coppieters KT, von Herrath MG (2011) Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 91:79–118
-
(2011)
Physiol Rev
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
80
-
-
77954128990
-
Immune cell crosstalk in type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3cXnvFSgt74%3D, PID: 20577267
-
Lehuen A, Diana J, Zaccone P, Cooke A (2010) Immune cell crosstalk in type 1 diabetes. Nat Rev Immunol 10:501–513
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 501-513
-
-
Lehuen, A.1
Diana, J.2
Zaccone, P.3
Cooke, A.4
-
81
-
-
0030890588
-
Cell death mediators in autoimmune diabetes—no shortage of suspects
-
COI: 1:CAS:528:DyaK2sXisVygsbg%3D, PID: 9094706
-
Benoist C, Mathis D (1997) Cell death mediators in autoimmune diabetes—no shortage of suspects. Cell 89:1–3
-
(1997)
Cell
, vol.89
, pp. 1-3
-
-
Benoist, C.1
Mathis, D.2
-
82
-
-
0035856952
-
Beta-cell death during progression to diabetes
-
COI: 1:CAS:528:DC%2BD38Xhtlymug%3D%3D, PID: 11742411
-
Mathis D, Vence L, Benoist C (2001) Beta-cell death during progression to diabetes. Nature 414:792–798
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
83
-
-
34548397755
-
Screening for insulitis in adult autoantibody-positive organ donors
-
PID: 17563060
-
In't Veld P, Lievens D, De Grijse J et al (2007) Screening for insulitis in adult autoantibody-positive organ donors. Diabetes 56:2400–2404
-
(2007)
Diabetes
, vol.56
, pp. 2400-2404
-
-
In't Veld, P.1
Lievens, D.2
De Grijse, J.3
-
85
-
-
84893708638
-
The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) program: goals, operational model and emerging findings
-
PID: 24325575
-
Pugliese A, Yang M, Kusmarteva I et al (2014) The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) program: goals, operational model and emerging findings. Pediatr Diabetes 15:1–9
-
(2014)
Pediatr Diabetes
, vol.15
, pp. 1-9
-
-
Pugliese, A.1
Yang, M.2
Kusmarteva, I.3
-
86
-
-
67649364114
-
The role of inflammation in insulitis and β-cell loss in type 1 diabetes
-
COI: 1:CAS:528:DC%2BD1MXjs1ymt7Y%3D, PID: 19352320
-
Eizirik DL, Colli ML, Ortis F (2009) The role of inflammation in insulitis and β-cell loss in type 1 diabetes. Nat Rev Endocrinol 5:219–226
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 219-226
-
-
Eizirik, D.L.1
Colli, M.L.2
Ortis, F.3
-
87
-
-
84952638473
-
Innate inflammation in type 1 diabetes
-
COI: 1:CAS:528:DC%2BC2MXosVGitL8%3D, PID: 25980926
-
Cabrera SM, Henschel AM, Hessner MJ (2016) Innate inflammation in type 1 diabetes. Transl Res 167:214–227
-
(2016)
Transl Res
, vol.167
, pp. 214-227
-
-
Cabrera, S.M.1
Henschel, A.M.2
Hessner, M.J.3
-
88
-
-
84891872943
-
Increased complement activation in human type 1 diabetes pancreata
-
PID: 24041678
-
Rowe P, Wasserfall C, Croker B et al (2013) Increased complement activation in human type 1 diabetes pancreata. Diabetes Care 36:3815–3817
-
(2013)
Diabetes Care
, vol.36
, pp. 3815-3817
-
-
Rowe, P.1
Wasserfall, C.2
Croker, B.3
-
89
-
-
84924022501
-
β cell death and dysfunction during type 1 diabetes development in at-risk individuals
-
PID: 25642774
-
Herold KC, Usmani-Brown S, Ghazi T et al (2015) β cell death and dysfunction during type 1 diabetes development in at-risk individuals. J Clin Invest 125:1163–1173
-
(2015)
J Clin Invest
, vol.125
, pp. 1163-1173
-
-
Herold, K.C.1
Usmani-Brown, S.2
Ghazi, T.3
-
90
-
-
84861868035
-
The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the diabetes prevention trial-type 1
-
COI: 1:CAS:528:DC%2BC38XotlGqtLg%3D, PID: 22618768
-
Sosenko JM, Skyler JS, Herold KC, Palmer JP, Type 1 Diabetes TrialNet Study Group, Diabetes Prevention Trial-Type 1 Study Group (2012) The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the diabetes prevention trial-type 1. Diabetes 61:1331–1337
-
(2012)
Diabetes
, vol.61
, pp. 1331-1337
-
-
Sosenko, J.M.1
Skyler, J.S.2
Herold, K.C.3
Palmer, J.P.4
-
91
-
-
0034746439
-
Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria
-
COI: 1:CAS:528:DC%2BD3MXhtVOgsLY%3D, PID: 11272162
-
Greenbaum CJ, Cuthbertson D, Krischer JP, Diabetes Prevention Trial of Type 1 Diabetes Study Group (2001) Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria. Diabetes 50:470–476
-
(2001)
Diabetes
, vol.50
, pp. 470-476
-
-
Greenbaum, C.J.1
Cuthbertson, D.2
Krischer, J.P.3
-
92
-
-
56649115489
-
Glucose and C-peptide changes in the perionset period of type 1 diabetes in the diabetes prevention trial-type 1
-
COI: 1:CAS:528:DC%2BD1cXhsVeqsL3I, PID: 18650369
-
Sosenko JM, Palmer JP, Rafkin-Mervis L et al (2008) Glucose and C-peptide changes in the perionset period of type 1 diabetes in the diabetes prevention trial-type 1. Diabetes Care 31:2188–2192
-
(2008)
Diabetes Care
, vol.31
, pp. 2188-2192
-
-
Sosenko, J.M.1
Palmer, J.P.2
Rafkin-Mervis, L.3
-
93
-
-
77950356610
-
Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset
-
COI: 1:CAS:528:DC%2BC3cXjslegur0%3D, PID: 20028949
-
Ferrannini E, Mari A, Nofrate V, Sosenko JM, Skyler JS, DPT-1 Study Group (2010) Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset. Diabetes 59:679–685
-
(2010)
Diabetes
, vol.59
, pp. 679-685
-
-
Ferrannini, E.1
Mari, A.2
Nofrate, V.3
Sosenko, J.M.4
Skyler, J.S.5
-
94
-
-
84865471364
-
Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth
-
COI: 1:CAS:528:DC%2BC38XhsFSrtr3K, PID: 22699293
-
Vehik K, Cuthbertson D, Boulware D et al (2012) Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth. Diabetes Care 35:1821–1825
-
(2012)
Diabetes Care
, vol.35
, pp. 1821-1825
-
-
Vehik, K.1
Cuthbertson, D.2
Boulware, D.3
-
95
-
-
33750140236
-
Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY)
-
PID: 17054445
-
Stene LC, Barriga K, Hoffman M et al (2006) Normal but increasing hemoglobin A1c levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). Pediatr Diabetes 7:247–253
-
(2006)
Pediatr Diabetes
, vol.7
, pp. 247-253
-
-
Stene, L.C.1
Barriga, K.2
Hoffman, M.3
-
96
-
-
84868107439
-
Alternative markers of hyperglycemia and risk of diabetes
-
COI: 1:CAS:528:DC%2BC38XhvFShs7nE, PID: 22875225
-
Juraschek SP, Steffes MW, Miller ER 3rd, Selvin E (2012) Alternative markers of hyperglycemia and risk of diabetes. Diabetes Care 35:2265–2270
-
(2012)
Diabetes Care
, vol.35
, pp. 2265-2270
-
-
Juraschek, S.P.1
Steffes, M.W.2
Miller, E.R.3
Selvin, E.4
-
97
-
-
53549094111
-
Relationship between β-cell mass and diabetes onset
-
COI: 1:CAS:528:DC%2BD1cXhsVeqsb7N, PID: 18834430
-
Matveyenko AV, Butler PC (2008) Relationship between β-cell mass and diabetes onset. Diabetes Obes Metab 10:23–31
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 23-31
-
-
Matveyenko, A.V.1
Butler, P.C.2
-
98
-
-
38949113134
-
Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus
-
PID: 18167535
-
Klinke DJ II (2008) Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus. PLoS One 3:e1374
-
(2008)
PLoS One
, vol.3
-
-
Klinke, D.J.1
-
99
-
-
70349671298
-
Preservation of β-cell function in autoantibody-positive youth with diabetes
-
COI: 1:CAS:528:DC%2BD1MXhtlehs7nM, PID: 19587365
-
Greenbaum CJ, Anderson AM, Dolan LM et al (2009) Preservation of β-cell function in autoantibody-positive youth with diabetes. Diabetes Care 32:1839–1844
-
(2009)
Diabetes Care
, vol.32
, pp. 1839-1844
-
-
Greenbaum, C.J.1
Anderson, A.M.2
Dolan, L.M.3
-
100
-
-
0041666293
-
β-Ccell function and the development of diabetes-related complications in the diabetes control and complications trial
-
PID: 12610045
-
Steffes MW, Sibley S, Jackson M, Thomas W (2003) β-Ccell function and the development of diabetes-related complications in the diabetes control and complications trial. Diabetes Care 26:832–836
-
(2003)
Diabetes Care
, vol.26
, pp. 832-836
-
-
Steffes, M.W.1
Sibley, S.2
Jackson, M.3
Thomas, W.4
-
101
-
-
84940105815
-
Distinct roles of β-cell mass and function during type 1 diabetes onset and remission
-
COI: 1:CAS:528:DC%2BC2MXhtVSiu7fO, PID: 25605805
-
Chmelova H, Cohrs CM, Chouinard JA et al (2015) Distinct roles of β-cell mass and function during type 1 diabetes onset and remission. Diabetes 64:2148–2160
-
(2015)
Diabetes
, vol.64
, pp. 2148-2160
-
-
Chmelova, H.1
Cohrs, C.M.2
Chouinard, J.A.3
-
102
-
-
0032055459
-
Effect of intensive therapy on residual β-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial
-
The Diabetes Control and Complications Trial Research Group (1998) Effect of intensive therapy on residual β-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. Ann Intern Med 128:517–523
-
(1998)
Ann Intern Med
, vol.128
, pp. 517-523
-
-
-
103
-
-
84891859307
-
Effectiveness of early intensive therapy on β-cell preservation in type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhvFaksLvO, PID: 24130350
-
Buckingham B, Beck RW, Ruedy KJ et al (2013) Effectiveness of early intensive therapy on β-cell preservation in type 1 diabetes. Diabetes Care 36:4030–4035
-
(2013)
Diabetes Care
, vol.36
, pp. 4030-4035
-
-
Buckingham, B.1
Beck, R.W.2
Ruedy, K.J.3
-
104
-
-
84921914093
-
Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors
-
COI: 1:CAS:528:DC%2BC2MXjvFSms7w%3D, PID: 25519449
-
Oram RA, McDonald TJ, Shields BM et al (2015) Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors. Diabetes Care 38:323–328
-
(2015)
Diabetes Care
, vol.38
, pp. 323-328
-
-
Oram, R.A.1
McDonald, T.J.2
Shields, B.M.3
-
105
-
-
27744603796
-
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?
-
COI: 1:CAS:528:DC%2BD2MXht1Skt7vJ, PID: 16205882
-
Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC (2005) Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia 48:2221–2228
-
(2005)
Diabetologia
, vol.48
, pp. 2221-2228
-
-
Meier, J.J.1
Bhushan, A.2
Butler, A.E.3
Rizza, R.A.4
Butler, P.C.5
-
106
-
-
84976585465
-
Diabetes complications in childhood diabetes-new biomarkers and technologies
-
PID: 26425403
-
Bjornstad P, Maahs DM (2015) Diabetes complications in childhood diabetes-new biomarkers and technologies. Curr Pediatr Rep 3:177–186
-
(2015)
Curr Pediatr Rep
, vol.3
, pp. 177-186
-
-
Bjornstad, P.1
Maahs, D.M.2
-
107
-
-
84903183608
-
Risk of type 1 diabetes progression in islet autoantibody-positive children can be further stratified using expression patterns of multiple genes implicated in peripheral blood lymphocyte activation and function
-
PID: 24595351
-
Jin Y, Sharma A, Bai S et al (2014) Risk of type 1 diabetes progression in islet autoantibody-positive children can be further stratified using expression patterns of multiple genes implicated in peripheral blood lymphocyte activation and function. Diabetes 63:2506–2515
-
(2014)
Diabetes
, vol.63
, pp. 2506-2515
-
-
Jin, Y.1
Sharma, A.2
Bai, S.3
-
108
-
-
40749100302
-
Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics
-
COI: 1:CAS:528:DC%2BD1cXotlKltQ%3D%3D, PID: 18209091
-
Wang X, Jia S, Geoffrey R, Alemzadeh R, Ghosh S, Hessner MJ (2008) Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J Immunol 180:1929–1937
-
(2008)
J Immunol
, vol.180
, pp. 1929-1937
-
-
Wang, X.1
Jia, S.2
Geoffrey, R.3
Alemzadeh, R.4
Ghosh, S.5
Hessner, M.J.6
-
109
-
-
84903184518
-
Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility
-
PID: 24550192
-
Kallionpaa H, Elo LL, Laajala E et al (2014) Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility. Diabetes 63:2402–2414
-
(2014)
Diabetes
, vol.63
, pp. 2402-2414
-
-
Kallionpaa, H.1
Elo, L.L.2
Laajala, E.3
-
110
-
-
84874516068
-
Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXht1Oiu7g%3D, PID: 23277452
-
Zhang Q, Fillmore TL, Schepmoes AA et al (2013) Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med 210:191–203
-
(2013)
J Exp Med
, vol.210
, pp. 191-203
-
-
Zhang, Q.1
Fillmore, T.L.2
Schepmoes, A.A.3
-
111
-
-
59649105735
-
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
-
COI: 1:CAS:528:DC%2BD1MXosFCg, PID: 19075291
-
Oresic M, Simell S, Sysi-Aho M et al (2008) Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes. J Exp Med 205:2975–2984
-
(2008)
J Exp Med
, vol.205
, pp. 2975-2984
-
-
Oresic, M.1
Simell, S.2
Sysi-Aho, M.3
-
112
-
-
84890747164
-
Decreased cord-blood phospholipids in young age-at-onset type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhsleisrrJ, PID: 23929934
-
La Torre D, Seppanen-Laakso T, Larsson HE et al (2013) Decreased cord-blood phospholipids in young age-at-onset type 1 diabetes. Diabetes 62:3951–3956
-
(2013)
Diabetes
, vol.62
, pp. 3951-3956
-
-
La Torre, D.1
Seppanen-Laakso, T.2
Larsson, H.E.3
-
113
-
-
84883230213
-
Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhtl2jtLvL, PID: 23630305
-
Oresic M, Gopalacharyulu P, Mykkanen J et al (2013) Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes. Diabetes 62:3268–3274
-
(2013)
Diabetes
, vol.62
, pp. 3268-3274
-
-
Oresic, M.1
Gopalacharyulu, P.2
Mykkanen, J.3
-
114
-
-
84958116286
-
The role of the intestinal microbiota in type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC28XjtFSntg%3D%3D, PID: 26729037
-
Knip M, Siljander H (2016) The role of the intestinal microbiota in type 1 diabetes mellitus. Nat Rev Endocrinol 12:154–167
-
(2016)
Nat Rev Endocrinol
, vol.12
, pp. 154-167
-
-
Knip, M.1
Siljander, H.2
-
115
-
-
84904806481
-
Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review
-
COI: 1:CAS:528:DC%2BC2cXlsFygsr8%3D, PID: 24662515
-
Watkins RA, Evans-Molina C, Blum JS, DiMeglio LA (2014) Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review. Transl Res 164:110–121
-
(2014)
Transl Res
, vol.164
, pp. 110-121
-
-
Watkins, R.A.1
Evans-Molina, C.2
Blum, J.S.3
DiMeglio, L.A.4
-
116
-
-
84923172399
-
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
-
COI: 1:CAS:528:DC%2BC2MXhvFCmsr0%3D, PID: 25650428
-
Gaglia JL, Harisinghani M, Aganj I et al (2015) Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients. Proc Natl Acad Sci U S A 112:2139–2144
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 2139-2144
-
-
Gaglia, J.L.1
Harisinghani, M.2
Aganj, I.3
-
117
-
-
44349193971
-
A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1
-
COI: 1:CAS:528:DC%2BD1cXktVSntr4%3D, PID: 18000175
-
Sosenko JM, Krischer JP, Palmer JP et al (2008) A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1. Diabetes Care 31:528–533
-
(2008)
Diabetes Care
, vol.31
, pp. 528-533
-
-
Sosenko, J.M.1
Krischer, J.P.2
Palmer, J.P.3
-
118
-
-
84866652634
-
Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high-risk population: receiver operating characteristic analysis
-
COI: 1:CAS:528:DC%2BC38Xhs1Gks77L, PID: 22787174
-
Xu P, Beam CA, Cuthbertson D et al (2012) Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high-risk population: receiver operating characteristic analysis. Diabetes Care 35:1975–1980
-
(2012)
Diabetes Care
, vol.35
, pp. 1975-1980
-
-
Xu, P.1
Beam, C.A.2
Cuthbertson, D.3
-
119
-
-
33744973987
-
Models for predicting type 1 diabetes in siblings of affected children
-
PID: 16505523
-
Mrena S, Virtanen SM, Laippala P et al (2006) Models for predicting type 1 diabetes in siblings of affected children. Diabetes Care 29:662–667
-
(2006)
Diabetes Care
, vol.29
, pp. 662-667
-
-
Mrena, S.1
Virtanen, S.M.2
Laippala, P.3
-
120
-
-
84935915908
-
The development, validation, and utility of the diabetes prevention trial-type 1 risk score (DPTRS)
-
PID: 26077017
-
Sosenko JM, Skyler JS, Palmer JP, The Diabetes Type 1 TrialNet and Diabetes Prevention Trial-Type 1 Study Groups (2015) The development, validation, and utility of the diabetes prevention trial-type 1 risk score (DPTRS). Curr Diab Rep 15:49
-
(2015)
Curr Diab Rep
, vol.15
, pp. 49
-
-
Sosenko, J.M.1
Skyler, J.S.2
Palmer, J.P.3
-
121
-
-
84862832735
-
Confirmation of novel type 1 diabetes risk loci in families
-
COI: 1:CAS:528:DC%2BC38Xjs1SjsLc%3D, PID: 22278338
-
Cooper JD, Howson JM, Smyth D et al (2012) Confirmation of novel type 1 diabetes risk loci in families. Diabetologia 55:996–1000
-
(2012)
Diabetologia
, vol.55
, pp. 996-1000
-
-
Cooper, J.D.1
Howson, J.M.2
Smyth, D.3
-
122
-
-
84928406046
-
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial
-
COI: 1:CAS:528:DC%2BC2MXhtFOls7rL, PID: 25898052
-
Bonifacio E, Ziegler AG, Klingensmith G et al (2015) Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial. JAMA 313:1541–1549
-
(2015)
JAMA
, vol.313
, pp. 1541-1549
-
-
Bonifacio, E.1
Ziegler, A.G.2
Klingensmith, G.3
-
123
-
-
45249111131
-
Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens
-
COI: 1:CAS:528:DC%2BD1cXmt12qsr0%3D, PID: 18359275
-
Hirai H, Miura J, Hu Y et al (2008) Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens. Clin Immunol 127:366–374
-
(2008)
Clin Immunol
, vol.127
, pp. 366-374
-
-
Hirai, H.1
Miura, J.2
Hu, Y.3
-
124
-
-
79955436241
-
Persistently autoantibody negative (PAN) type 1 diabetes mellitus in children
-
COI: 1:CAS:528:DC%2BC3MXot1yjsrY%3D, PID: 21518407
-
Hameed S, Ellard S, Woodhead HJ et al (2011) Persistently autoantibody negative (PAN) type 1 diabetes mellitus in children. Pediatr Diabetes 12:142–149
-
(2011)
Pediatr Diabetes
, vol.12
, pp. 142-149
-
-
Hameed, S.1
Ellard, S.2
Woodhead, H.J.3
-
125
-
-
84875431011
-
Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: action LADA 7
-
PID: 23248199
-
Hawa MI, Kolb H, Schloot N et al (2013) Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: action LADA 7. Diabetes Care 36:908–913
-
(2013)
Diabetes Care
, vol.36
, pp. 908-913
-
-
Hawa, M.I.1
Kolb, H.2
Schloot, N.3
-
126
-
-
84903552407
-
Type 1 diabetes through the life span: a position statement of the American Diabetes Association
-
PID: 24935775
-
Chiang JL, Kirkman MS, Laffel LM, Peters AL, Type 1 Diabetes Sourcebook Authors (2014) Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes Care 37:2034–2054
-
(2014)
Diabetes Care
, vol.37
, pp. 2034-2054
-
-
Chiang, J.L.1
Kirkman, M.S.2
Laffel, L.M.3
Peters, A.L.4
-
127
-
-
84860783172
-
Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden
-
COI: 1:CAS:528:DC%2BC38XmvVertrs%3D
-
Carlsson A, Kockum I, Lindblad B et al (2012) Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden. Int J Obes 36:718–724
-
(2012)
Int J Obes
, vol.36
, pp. 718-724
-
-
Carlsson, A.1
Kockum, I.2
Lindblad, B.3
|