A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children

Diabetologia

Volumn 59, Issue 10, 2016, Pages 2172-2180

  Endesfelder, David ^a   Hagen, Michael ^a   Winkler, Christiane ^a,b,c,d   Haupt, Florian ^a,b,c   Zillmer, Stephanie ^a,b,c   Knopff, Annette ^a,b   Bonifacio, Ezio ^a,d,e,f   Ziegler, Anette G ^a,b,c,d   zu Castell, Wolfgang ^a,g   Achenbach, Peter ^a,b,c,d  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^d Forschergruppe Diabetes eV   (Germany)

^e CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^f DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Clustering; Islet autoantibody; Longitudinal; Profiles; Progression; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; GLUTAMATE DECARBOXYLASE ANTIBODY; INSULIN ANTIBODY; INSULINOMA ASSOCIATED ANTIGEN 2 ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; ZINC TRANSPORTER 8 ANTIBODY; CATION TRANSPORT PROTEIN; GLUTAMATE DECARBOXYLASE; INSULIN; SLC30A8 PROTEIN, HUMAN;

ALGORITHM; ARTICLE; AUTOIMMUNITY; CHILD; CONTROLLED STUDY; DELAYED PROGRESSION; DISEASE COURSE; FOLLOW UP; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RISK FACTOR; SCHOOL CHILD; SEROCONVERSION; CLUSTER ANALYSIS; FEMALE; IMMUNOLOGY; MALE; METABOLISM; PANCREAS ISLET; PATHOLOGY; PROSPECTIVE STUDY;

ALGORITHMS; AUTOANTIBODIES; CATION TRANSPORT PROTEINS; CLUSTER ANALYSIS; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; GLUTAMATE DECARBOXYLASE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; PROSPECTIVE STUDIES;

EID: 84978120392     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-4050-0     Document Type: Article

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