메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

(19)  Törn, Carina a   Liu, Xiang b   Hagopian, William c   Lernmark, Åke a   Simell, Olli d   Rewers, Marian e   Ziegler, Anette G f   Schatz, Desmond g   Akolkar, Beena h   Onengut Gumuscu, Suna i   Chen, Wei Min i   Toppari, Jorma d,j   Mykkänen, Juha d,j   Ilonen, Jorma j   Rich, Stephen S i   She, Jin Xiong k   Sharma, Ashok k   Steck, Andrea e   Krischer, Jeffrey b  


Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; COMPLEMENT COMPONENT C3;

EID: 84975091581     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep27887     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 84891872943 scopus 로고    scopus 로고
    • Increased complement activation in human type 1 diabetes pancreata
    • Rowe, P. et al. Increased complement activation in human type 1 diabetes pancreata. Diabetes Care 36, 3815-3817 (2013).
    • (2013) Diabetes Care , vol.36 , pp. 3815-3817
    • Rowe, P.1
  • 2
    • 84874516068 scopus 로고    scopus 로고
    • Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes
    • Zhang, Q. et al. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med. 210, 191-203 (2013).
    • (2013) J Exp Med. , vol.210 , pp. 191-203
    • Zhang, Q.1
  • 4
    • 84903184518 scopus 로고    scopus 로고
    • Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility
    • Kallionpaa, H. et al. Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility. Diabetes 63, 2402-2414 (2014).
    • (2014) Diabetes , vol.63 , pp. 2402-2414
    • Kallionpaa, H.1
  • 5
    • 0019231235 scopus 로고
    • Cytotoxic activation of complement by mouse pancreatic islet cells
    • Idahl, L. A., Sehlin, J., Taljedal, I. B. & Thornell, L. E. Cytotoxic activation of complement by mouse pancreatic islet cells. Diabetes 29, 636-642 (1980).
    • (1980) Diabetes , vol.29 , pp. 636-642
    • Idahl, L.A.1    Sehlin, J.2    Taljedal, I.B.3    Thornell, L.E.4
  • 6
    • 0024586891 scopus 로고
    • Complotypes and extended haplotypes in laboratory medicine
    • Alper, C. A., Awdeh, Z. L. & Yunis, E. J. Complotypes and extended haplotypes in laboratory medicine. Complement Inflamm. 6, 8-18 (1989).
    • (1989) Complement Inflamm. , vol.6 , pp. 8-18
    • Alper, C.A.1    Awdeh, Z.L.2    Yunis, E.J.3
  • 7
    • 0020683432 scopus 로고
    • HLA and complement allotypes in Type 1 (insulin-dependent) diabetes
    • McCluskey, J. et al. HLA and complement allotypes in Type 1 (insulin-dependent) diabetes. Diabetologia 24, 162-165 (1983).
    • (1983) Diabetologia , vol.24 , pp. 162-165
    • McCluskey, J.1
  • 8
    • 0021719447 scopus 로고
    • Genetic heterogeneity of insulin-dependent (type I) diabetes mellitus: Evidence from a study of extended haplotypes
    • Rich, S. S., Weitkamp, L. R. & Barbosa, J. Genetic heterogeneity of insulin-dependent (type I) diabetes mellitus: evidence from a study of extended haplotypes. Am J Hum Genet. 36, 1015-1023 (1984).
    • (1984) Am J Hum Genet. , vol.36 , pp. 1015-1023
    • Rich, S.S.1    Weitkamp, L.R.2    Barbosa, J.3
  • 9
    • 0035311823 scopus 로고    scopus 로고
    • Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1-DRB1 disease loci
    • Zavattari, P. et al. Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1,-DRB1 disease loci. Hum Mol Genet. 10, 881-889 (2001).
    • (2001) Hum Mol Genet. , vol.10 , pp. 881-889
    • Zavattari, P.1
  • 10
    • 36849012027 scopus 로고    scopus 로고
    • Localization of type 1 diabetes susceptibility to the MHC class i genes HLA-B and HLA-A
    • Nejentsev, S. et al. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450, 887-892 (2007).
    • (2007) Nature , vol.450 , pp. 887-892
    • Nejentsev, S.1
  • 11
    • 78049246370 scopus 로고    scopus 로고
    • HLA class i and genetic susceptibility to type 1 diabetes: Results from the Type 1 Diabetes Genetics Consortium
    • Noble, J. A. et al. HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. Diabetes 59, 2972-2979 (2010).
    • (2010) Diabetes , vol.59 , pp. 2972-2979
    • Noble, J.A.1
  • 12
    • 77649184584 scopus 로고    scopus 로고
    • The complement system in systemic autoimmune disease
    • Chen, M., Daha, M. R. & Kallenberg, C. G. The complement system in systemic autoimmune disease. J Autoimmun. 34, J276-286 (2010).
    • (2010) J Autoimmun. , vol.34 , pp. J276-J286
    • Chen, M.1    Daha, M.R.2    Kallenberg, C.G.3
  • 13
    • 84896970663 scopus 로고    scopus 로고
    • Complement and its receptors: New insights into human disease
    • Holers, V. M. Complement and its receptors: new insights into human disease. Ann Rev Immunol. 32, 433-459 (2014).
    • (2014) Ann Rev Immunol. , vol.32 , pp. 433-459
    • Holers, V.M.1
  • 14
    • 44349193971 scopus 로고    scopus 로고
    • A risk score for type 1 diabetes derived from autoantibody-positive participants in the Diabetes Prevention Trial-Type 1
    • Sosenko, J. M. et al. A risk score for type 1 diabetes derived from autoantibody-positive participants in the Diabetes Prevention Trial-Type 1. Diabetes Care 31, 528-533 (2008).
    • (2008) Diabetes Care , vol.31 , pp. 528-533
    • Sosenko, J.M.1
  • 15
    • 0019400455 scopus 로고
    • The pancreatic islets in diabetes
    • Gepts, W. & Lecompte, P. M. The pancreatic islets in diabetes. Am J Med. 70, 105-115 (1981).
    • (1981) Am J Med. , vol.70 , pp. 105-115
    • Gepts, W.1    Lecompte, P.M.2
  • 16
    • 75149130955 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association.
    • American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 33 Suppl 1, S62-69 (2010).
    • (2010) Diabetes Care. , vol.33 , pp. S62-S69
  • 17
    • 4143139832 scopus 로고    scopus 로고
    • Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: A population-based study in the United Kingdom
    • Lambert, A. P. et al. Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: A population-based study in the United Kingdom. J Clin Endocrinol Metab. 89, 4037-4043 (2004).
    • (2004) J Clin Endocrinol Metab. , vol.89 , pp. 4037-4043
    • Lambert, A.P.1
  • 18
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • Barrett, J. C. et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet. 41, 703-707 (2009).
    • (2009) Nat Genet. , vol.41 , pp. 703-707
    • Barrett, J.C.1
  • 19
    • 84862832735 scopus 로고    scopus 로고
    • Confirmation of novel type 1 diabetes risk loci in families
    • Cooper, J. D. et al. Confirmation of novel type 1 diabetes risk loci in families. Diabetologia 55, 996-1000 (2012).
    • (2012) Diabetologia , vol.55 , pp. 996-1000
    • Cooper, J.D.1
  • 21
    • 0016311038 scopus 로고
    • Capacity of complement c3 phenotypes to bind on to mononuclear cells in man
    • Arvilommi, H. Capacity of complement c3 phenotypes to bind on to mononuclear cells in man. Nature 251, 740-741 (1974).
    • (1974) Nature , vol.251 , pp. 740-741
    • Arvilommi, H.1
  • 22
    • 34547764305 scopus 로고    scopus 로고
    • Complement C3 variant and the risk of age-related macular degeneration
    • Yates, J. R. et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med. 357, 553-561 (2007).
    • (2007) N Engl J Med. , vol.357 , pp. 553-561
    • Yates, J.R.1
  • 23
    • 84944754011 scopus 로고    scopus 로고
    • Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: A meta-analysis
    • Zhang, M. X. et al. Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: A meta-analysis. Genet Mol Res. 14, 12567-12576 (2015).
    • (2015) Genet Mol Res. , vol.14 , pp. 12567-12576
    • Zhang, M.X.1
  • 24
    • 84859995395 scopus 로고    scopus 로고
    • A novel mechanism for hypofibrinolysis in diabetes: The role of complement C3
    • Hess, K. et al. A novel mechanism for hypofibrinolysis in diabetes: The role of complement C3. Diabetologia 55, 1103-1113 (2012).
    • (2012) Diabetologia , vol.55 , pp. 1103-1113
    • Hess, K.1
  • 25
    • 84886793012 scopus 로고    scopus 로고
    • Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils
    • Zhou, Y. et al. Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils. Arthritis Rheum. 65, 2907-2916 (2013).
    • (2013) Arthritis Rheum. , vol.65 , pp. 2907-2916
    • Zhou, Y.1
  • 26
    • 67849133217 scopus 로고    scopus 로고
    • Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing
    • Douglas, K. B. et al. Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing. Genes Immun. 10, 457-469 (2009).
    • (2009) Genes Immun. , vol.10 , pp. 457-469
    • Douglas, K.B.1
  • 27
    • 12544252996 scopus 로고    scopus 로고
    • Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2
    • Solovjov, D. A., Pluskota, E. & Plow, E. F. Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2. J Biol Chem. 280, 1336-1345 (2005).
    • (2005) J Biol Chem. , vol.280 , pp. 1336-1345
    • Solovjov, D.A.1    Pluskota, E.2    Plow, E.F.3
  • 29
    • 0026639571 scopus 로고
    • Nuclear localization of the Epstein-Barr virus/C3d receptor (CR2) in the human Burkitt B lymphoma cell, Raji
    • Gauffre, A. et al. Nuclear localization of the Epstein-Barr virus/C3d receptor (CR2) in the human Burkitt B lymphoma cell, Raji. Mol Immunol. 29, 1113-1120 (1992).
    • (1992) Mol Immunol. , vol.29 , pp. 1113-1120
    • Gauffre, A.1
  • 30
    • 0035399831 scopus 로고    scopus 로고
    • The role of the CD19/CD21 complex in B cell processing and presentation of complementtagged antigens
    • Cherukuri, A., Cheng, P. C. & Pierce, S. K. The role of the CD19/CD21 complex in B cell processing and presentation of complementtagged antigens. J Immunol. 167, 163-172 (2001).
    • (2001) J Immunol. , vol.167 , pp. 163-172
    • Cherukuri, A.1    Cheng, P.C.2    Pierce, S.K.3
  • 31
    • 60349127531 scopus 로고    scopus 로고
    • Complement activation and inhibition: A delicate balance
    • Sjoberg, A. P., Trouw, L. A. & Blom, A. M. Complement activation and inhibition: A delicate balance. Trends Immunol. 30, 83-90 (2009).
    • (2009) Trends Immunol. , vol.30 , pp. 83-90
    • Sjoberg, A.P.1    Trouw, L.A.2    Blom, A.M.3
  • 32
    • 34548783929 scopus 로고    scopus 로고
    • The Environmental Determinants of Diabetes in the Young (TEDDY) study: Study design
    • The TEDDY Study Group.
    • The TEDDY Study Group. The Environmental Determinants of Diabetes in the Young (TEDDY) study: study design. Pediatr Diabetes 8, 286-298 (2007).
    • (2007) Pediatr Diabetes , vol.8 , pp. 286-298
  • 33
    • 80053036722 scopus 로고    scopus 로고
    • The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants
    • Hagopian, W. A. et al. The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants. Pediatr Diabetes 12, 733-743 (2011).
    • (2011) Pediatr Diabetes , vol.12 , pp. 733-743
    • Hagopian, W.A.1
  • 34
    • 41849115906 scopus 로고    scopus 로고
    • Diabetes Antibody Standardization Program: Evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2
    • Torn, C., Mueller, P. W., Schlosser, M., Bonifacio, E. & Bingley, P. J. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2. Diabetologia 51, 846-852 (2008).
    • (2008) Diabetologia , vol.51 , pp. 846-852
    • Torn, C.1    Mueller, P.W.2    Schlosser, M.3    Bonifacio, E.4    Bingley, P.J.5
  • 35
    • 70350582632 scopus 로고    scopus 로고
    • Comparison of insulin autoantibody: Polyethylene glycol and micro-IAA 1-day and 7-day assays
    • Babaya, N. et al. Comparison of insulin autoantibody: polyethylene glycol and micro-IAA 1-day and 7-day assays. Diabetes Metab Res Rev. 25, 665-670 (2009).
    • (2009) Diabetes Metab Res Rev. , vol.25 , pp. 665-670
    • Babaya, N.1
  • 36
    • 77954949830 scopus 로고    scopus 로고
    • Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for National Institute of Diabetes and Digestive and Kidney Diseases Consortia
    • Bonifacio, E. et al. Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for National Institute of Diabetes and Digestive and Kidney Diseases Consortia. J Clin Endocrinol Metab. 95, 3360-3367 (2010).
    • (2010) J Clin Endocrinol Metab. , vol.95 , pp. 3360-3367
    • Bonifacio, E.1
  • 37
    • 78649321907 scopus 로고    scopus 로고
    • Diabetes Antibody Standardization Program: Evaluation of assays for insulin autoantibodies
    • Schlosser, M. et al. Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies. Diabetologia 53, 2611-2620 (2010).
    • (2010) Diabetologia , vol.53 , pp. 2611-2620
    • Schlosser, M.1
  • 38
    • 78049493498 scopus 로고    scopus 로고
    • Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots
    • Dantonio, P. et al. Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots. J Diabetes Sci Technol. 4, 929-941 (2010).
    • (2010) J Diabetes Sci Technol. , vol.4 , pp. 929-941
    • Dantonio, P.1
  • 39
    • 84981556018 scopus 로고    scopus 로고
    • Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study
    • Torn, C. et al. Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study. Diabetes 64, 1818-1829 (2015).
    • (2015) Diabetes , vol.64 , pp. 1818-1829
    • Torn, C.1
  • 40
    • 79953752268 scopus 로고
    • Regression analysis of multivariate incomplete failure time data by modeling marginal distribution
    • Wei, L. J., Lin, D. Y. & Weissfeld, L. Regression analysis of multivariate incomplete failure time data by modeling marginal distribution. J Am Stat Assoc. 84, 1065-1073 (1989).
    • (1989) J Am Stat Assoc. , vol.84 , pp. 1065-1073
    • Wei, L.J.1    Lin, D.Y.2    Weissfeld, L.3
  • 41
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 81, 559-575 (2007).
    • (2007) Am J Hum Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 42
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A. L. et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 38, 904-909 (2006).
    • (2006) Nat Genet. , vol.38 , pp. 904-909
    • Price, A.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.