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Volumn 93, Issue 3, 2015, Pages 271-276

Epigenomics of autoimmune diseases

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE DISEASE; AUTOIMMUNITY; EPIGENETICS; GENETIC VARIABILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MULTIPLE SCLEROSIS; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA METHYLATION; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; PROCEDURES; TRENDS;

EID: 84924966095     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2015.18     Document Type: Review
Times cited : (39)

References (82)
  • 1
    • 0027537296 scopus 로고
    • Cpg methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita N, Fujita T, Aoike A, Osifchin NE, Robbins PD, Sakai T. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 1993; 8: 1063-1067
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 2
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-Type-specific gene expression
    • Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF et al. Histone modifications at human enhancers reflect global cell-Type-specific gene expression. Nature 2009; 459: 108-112
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5    Harp, L.F.6
  • 3
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui K, Zang C, Roh TY, Schones DE, Childs RW, Peng W et al. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 2009; 4: 80-93
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1    Zang, C.2    Roh, T.Y.3    Schones, D.E.4    Childs, R.W.5    Peng, W.6
  • 4
    • 77953809032 scopus 로고    scopus 로고
    • Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
    • Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M et al. Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 2010; 6: 479-491
    • (2010) Cell Stem Cell , vol.6 , pp. 479-491
    • Hawkins, R.D.1    Hon, G.C.2    Lee, L.K.3    Ngo, Q.4    Lister, R.5    Pelizzola, M.6
  • 5
    • 80053622239 scopus 로고    scopus 로고
    • Dynamic chromatin states in human es cells reveal potential regulatory sequences and genes involved in pluripotency
    • Hawkins RD, Hon GC, Yang C, Antosiewicz-Bourget JE, Lee LK, Ngo QM et al. Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency. Cell Res 2011; 21: 1393-1409
    • (2011) Cell Res , vol.21 , pp. 1393-1409
    • Hawkins, R.D.1    Hon, G.C.2    Yang, C.3    Antosiewicz-Bourget, J.E.4    Lee, L.K.5    Ngo, Q.M.6
  • 6
    • 84878282421 scopus 로고    scopus 로고
    • Epigenomic analysis of multilineage differentiation of human embryonic stem cells
    • Xie W, Schultz MD, Lister R, Hou Z, Rajagopal N, Ray P et al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 2013; 153: 1134-1148
    • (2013) Cell , vol.153 , pp. 1134-1148
    • Xie, W.1    Schultz, M.D.2    Lister, R.3    Hou, Z.4    Rajagopal, N.5    Ray, P.6
  • 7
    • 84879604583 scopus 로고    scopus 로고
    • Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human t helper 1 and t helper 2 cell polarization
    • Hawkins RD, Larjo A, Tripathi SK, Wagner U, Luu Y, Lönnberg T et al. Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization. Immunity 2013; 38: 1271-1284
    • (2013) Immunity , vol.38 , pp. 1271-1284
    • Hawkins, R.D.1    Larjo, A.2    Tripathi, S.K.3    Wagner, U.4    Luu, Y.5    Lönnberg, T.6
  • 8
    • 84881526410 scopus 로고    scopus 로고
    • Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
    • Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD et al. Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell 2013; 51: 310-325
    • (2013) Mol Cell , vol.51 , pp. 310-325
    • Kaikkonen, M.U.1    Spann, N.J.2    Heinz, S.3    Romanoski, C.E.4    Allison, K.A.5    Stender, J.D.6
  • 9
    • 84923326765 scopus 로고    scopus 로고
    • Genetic and epigenetic fine mapping of causal autoimmune disease variants
    • Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 2015; 518: 337-343
    • (2015) Nature , vol.518 , pp. 337-343
    • Farh, K.K.1    Marson, A.2    Zhu, J.3    Kleinewietfeld, M.4    Housley, W.J.5    Beik, S.6
  • 10
    • 84904644906 scopus 로고    scopus 로고
    • Epigenomic analysis of primary human t cells reveals enhancers associated with th2 memory cell differentiation and asthma susceptibility
    • Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L et al. Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nat Immunol 2014; 15: 777-788
    • (2014) Nat Immunol , vol.15 , pp. 777-788
    • Seumois, G.1    Chavez, L.2    Gerasimova, A.3    Lienhard, M.4    Omran, N.5    Kalinke, L.6
  • 12
    • 64349091471 scopus 로고    scopus 로고
    • Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
    • Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 2009; 27: 361-368
    • (2009) Nat Biotechnol , vol.27 , pp. 361-368
    • Ball, M.P.1    Li, J.B.2    Gao, Y.3    Lee, J.H.4    Leproust, E.M.5    Park, I.H.6
  • 14
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear dna base 5-hydroxymethylcytosine is present in purkinje neurons and the brain
    • Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009; 324: 929-930
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 15
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian dna by mll partner tet1
    • Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009; 324: 930-935
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5    Brudno, Y.6
  • 16
    • 84870620786 scopus 로고    scopus 로고
    • Tet-Assisted bisulfite sequencing of 5-hydroxymethylcytosine
    • Yu M, Hon GC, Szulwach KE, Song CX, Jin P, Ren B et al. Tet-Assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc 2012; 7: 2159-2170
    • (2012) Nat Protoc , vol.7 , pp. 2159-2170
    • Yu, M.1    Hon, G.C.2    Szulwach, K.E.3    Song, C.X.4    Jin, P.5    Ren, B.6
  • 17
    • 84908204470 scopus 로고    scopus 로고
    • 5mc oxidation by tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation
    • Hon GC, Song CX, Du T, Jin F, Selvaraj S, Lee AY et al. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation. Mol Cell 2014; 56: 286-297
    • (2014) Mol Cell , vol.56 , pp. 286-297
    • Hon, G.C.1    Song, C.X.2    Du, T.3    Jin, F.4    Selvaraj, S.5    Lee, A.Y.6
  • 18
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008; 40: 897-903
    • (2008) Nat Genet , vol.40 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3    Schones, D.E.4    Barski, A.5    Cuddapah, S.6
  • 19
    • 78049402859 scopus 로고    scopus 로고
    • Molecular signals of epigenetic states
    • Bonasio R, Tu S, Reinberg D. Molecular signals of epigenetic states. Science 2010; 330: 612-616
    • (2010) Science , vol.330 , pp. 612-616
    • Bonasio, R.1    Tu, S.2    Reinberg, D.3
  • 20
    • 84869864800 scopus 로고    scopus 로고
    • Epidemiology of environmental exposures and human autoimmune diseases: Findings from a national institute of environmental health sciences expert panel workshop
    • Miller FW, Alfredsson L, Costenbader KH, Kamen DL, Nelson LM, Norris JM et al. Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel Workshop. J Autoimmun 2012; 39: 259-271
    • (2012) J Autoimmun , vol.39 , pp. 259-271
    • Miller, F.W.1    Alfredsson, L.2    Costenbader, K.H.3    Kamen, D.L.4    Nelson, L.M.5    Norris, J.M.6
  • 21
    • 84869863290 scopus 로고    scopus 로고
    • Mechanisms of environmental influence on human autoimmunity: A national institute of environmental health sciences expert panel workshop
    • Selmi C, Leung PS, Sherr DH, Diaz M, Nyland JF, Monestier M et al. Mechanisms of environmental influence on human autoimmunity: a National Institute of Environmental Health Sciences expert panel workshop. J Autoimmun 2012; 39: 272-284
    • (2012) J Autoimmun , vol.39 , pp. 272-284
    • Selmi, C.1    Leung, P.S.2    Sherr, D.H.3    Diaz, M.4    Nyland, J.F.5    Monestier, M.6
  • 22
    • 0037079918 scopus 로고    scopus 로고
    • Clinical indicators of immune restoration following highly active antiretroviral therapy
    • Cooney EL. Clinical indicators of immune restoration following highly active antiretroviral therapy. Clin Infect Dis 2002; 34: 224-233
    • (2002) Clin Infect Dis , vol.34 , pp. 224-233
    • Cooney, E.L.1
  • 23
    • 79955096234 scopus 로고    scopus 로고
    • Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the hnf4a gene in rat pancreatic islets
    • Sandovici I, Smith NH, Nitert MD, Ackers-Johnson M, Uribe-Lewis S, Ito Y et al. Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets. Proc Natl Acad Sci USA 2011; 108: 5449-5454
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 5449-5454
    • Sandovici, I.1    Smith, N.H.2    Nitert, M.D.3    Ackers-Johnson, M.4    Uribe-Lewis, S.5    Ito, Y.6
  • 24
    • 33144488275 scopus 로고    scopus 로고
    • Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (igf2) locus
    • Waterland RA, Lin JR, Smith CA, Jirtle RL. Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum Mol Genet 2006; 15: 705-716
    • (2006) Hum Mol Genet , vol.15 , pp. 705-716
    • Waterland, R.A.1    Lin, J.R.2    Smith, C.A.3    Jirtle, R.L.4
  • 26
    • 70349573301 scopus 로고    scopus 로고
    • Dna methylation and gene expression differences in children conceived in vitro or in vivo
    • Katari S, Turan N, Bibikova M, Erinle O, Chalian R, Foster M et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet 2009; 18: 3769-3778
    • (2009) Hum Mol Genet , vol.18 , pp. 3769-3778
    • Katari, S.1    Turan, N.2    Bibikova, M.3    Erinle, O.4    Chalian, R.5    Foster, M.6
  • 27
  • 29
    • 80052511814 scopus 로고    scopus 로고
    • Micrornas are key regulators controlling inkt and regulatory t-cell development and function
    • Zhou L, Park JJ, Zheng Q, Dong Z, Mi Q. MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function. Cell Mol Immunol 2011; 8: 380-387
    • (2011) Cell Mol Immunol , vol.8 , pp. 380-387
    • Zhou, L.1    Park, J.J.2    Zheng, Q.3    Dong, Z.4    Mi, Q.5
  • 30
    • 78651295381 scopus 로고    scopus 로고
    • Hdac inhibition by lbh589 affects the phenotype and function of human myeloid dendritic cells
    • Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P et al. HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia 2011; 25: 161-168
    • (2011) Leukemia , vol.25 , pp. 161-168
    • Song, W.1    Tai, Y.T.2    Tian, Z.3    Hideshima, T.4    Chauhan, D.5    Nanjappa, P.6
  • 31
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of t-helper-cell differentiation
    • Wilson CB, Rowell E, Sekimata M. Epigenetic control of T-helper-cell differentiation. Nat Rev Immunol 2009; 9: 91-105
    • (2009) Nat Rev Immunol , vol.9 , pp. 91-105
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 32
    • 14244260068 scopus 로고    scopus 로고
    • Dna methylation and the expanding epigenetics of t cell lineage commitment
    • Wilson CB, Makar KW, Shnyreva M, Fitzpatrick DR. DNA methylation and the expanding epigenetics of T cell lineage commitment. Semin Immunol 2005; 17: 105-119
    • (2005) Semin Immunol , vol.17 , pp. 105-119
    • Wilson, C.B.1    Makar, K.W.2    Shnyreva, M.3    Fitzpatrick, D.R.4
  • 33
    • 84863724616 scopus 로고    scopus 로고
    • An epigenetic silencing pathway controlling t helper 2 cell lineage commitment
    • Allan RS, Zueva E, Cammas F, Schreiber HA, Masson V, Belz GT et al. An epigenetic silencing pathway controlling T helper 2 cell lineage commitment. Nature 2012; 487: 249-253
    • (2012) Nature , vol.487 , pp. 249-253
    • Allan, R.S.1    Zueva, E.2    Cammas, F.3    Schreiber, H.A.4    Masson, V.5    Belz, G.T.6
  • 34
    • 79957550675 scopus 로고    scopus 로고
    • Genome-wide dna methylation patterns in cd4+ t cells from patients with systemic lupus erythematosus
    • Jeffries MA, Dozmorov M, Tang Y, Merrill JT, Wren JD, Sawalha AH. Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus. Epigenetics 2011; 6: 593-601
    • (2011) Epigenetics , vol.6 , pp. 593-601
    • Jeffries, M.A.1    Dozmorov, M.2    Tang, Y.3    Merrill, J.T.4    Wren, J.D.5    Sawalha, A.H.6
  • 35
    • 70350049103 scopus 로고    scopus 로고
    • Abnormal dna methylation in cd4+ t cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis
    • Lei W, Luo Y, Lei W, Luo Y, Yan K, Zhao S et al. Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis. Scand J Rheumatol 2009; 38: 369-374
    • (2009) Scand J Rheumatol , vol.38 , pp. 369-374
    • Lei, W.1    Luo, Y.2    Lei, W.3    Luo, Y.4    Yan, K.5    Zhao, S.6
  • 36
    • 0025666735 scopus 로고
    • Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis
    • Richardson B, Scheinbart L, Strahler J, Gross L, Hanash S, Johnson M. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum 1990; 33: 1665-1673
    • (1990) Arthritis Rheum , vol.33 , pp. 1665-1673
    • Richardson, B.1    Scheinbart, L.2    Strahler, J.3    Gross, L.4    Hanash, S.5    Johnson, M.6
  • 37
    • 0036021150 scopus 로고    scopus 로고
    • Role of dna methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus
    • Okada M, Ogasawara H, Kaneko H, Hishikawa T, Sekigawa I, Hashimoto H et al. Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus. J Rheumatol 2002; 29: 1678-1682
    • (2002) J Rheumatol , vol.29 , pp. 1678-1682
    • Okada, M.1    Ogasawara, H.2    Kaneko, H.3    Hishikawa, T.4    Sekigawa, I.5    Hashimoto, H.6
  • 38
    • 79956191491 scopus 로고    scopus 로고
    • Analysis of associations between the patterns of global dna hypomethylation and expression of dna methyltransferase in patients with systemic lupus erythematosus
    • Zhu X, Liang J, Li F, Yang Y, Xiang L, Xu J. Analysis of associations between the patterns of global DNA hypomethylation and expression of DNA methyltransferase in patients with systemic lupus erythematosus. Int J Dermatol 2011; 50: 697-704
    • (2011) Int J Dermatol , vol.50 , pp. 697-704
    • Zhu, X.1    Liang, J.2    Li, F.3    Yang, Y.4    Xiang, L.5    Xu, J.6
  • 40
    • 0024988560 scopus 로고
    • Quantitative changes in t cell dna methylation occur during differentiation and ageing
    • Golbus J, Palella TD, Richardson BC. Quantitative changes in T cell DNA methylation occur during differentiation and ageing. Eur J Immunol 1990; 20: 1869-1872
    • (1990) Eur J Immunol , vol.20 , pp. 1869-1872
    • Golbus, J.1    Palella, T.D.2    Richardson, B.C.3
  • 41
    • 0036098657 scopus 로고    scopus 로고
    • Age-dependent dna methylation changes in the itgal (cd11a) promoter
    • Zhang Z, Deng C, Lu Q, Richardson B. Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter. Mech Ageing Dev 2002; 123: 1257-1268
    • (2002) Mech Ageing Dev , vol.123 , pp. 1257-1268
    • Zhang, Z.1    Deng, C.2    Lu, Q.3    Richardson, B.4
  • 42
    • 84884634092 scopus 로고    scopus 로고
    • Genome-wide dna methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to cd4+ t-cell populations
    • Absher DM, Li X, Waite LL, Gibson A, Roberts K, Edberg J et al. Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet 2013; 9: e1003678
    • (2013) PLoS Genet , vol.9 , pp. e1003678
    • Absher, D.M.1    Li, X.2    Waite, L.L.3    Gibson, A.4    Roberts, K.5    Edberg, J.6
  • 43
    • 44349087706 scopus 로고    scopus 로고
    • Abnormal histone modification patterns in lupus cd4+ t cells
    • Hu N, Qiu X, Luo Y, Yuan J, Li Y, Lei W et al. Abnormal histone modification patterns in lupus CD4+ T cells. J Rheumatol 2008; 35: 804-810
    • (2008) J Rheumatol , vol.35 , pp. 804-810
    • Hu, N.1    Qiu, X.2    Luo, Y.3    Yuan, J.4    Li, Y.5    Lei, W.6
  • 44
    • 77951638287 scopus 로고    scopus 로고
    • Noncoding rna gas5 is a growth arrest- and starvation-Associated repressor of the glucocorticoid receptor
    • ra8
    • Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP. Noncoding RNA gas5 is a growth arrest- And starvation-Associated repressor of the glucocorticoid receptor. Sci Signal 2010; 3: ra8
    • (2010) Sci Signal , pp. 3
    • Kino, T.1    Hurt, D.E.2    Ichijo, T.3    Nader, N.4    Chrousos, G.P.5
  • 45
    • 0028824955 scopus 로고
    • Cpg DNA a pathogenic factor in systemic lupus erythematosus?
    • Krieg AM. CpG DNA: a pathogenic factor in systemic lupus erythematosus? J Clin Immunol 1995; 15: 284-292
    • (1995) J Clin Immunol , vol.15 , pp. 284-292
    • Krieg, A.M.1
  • 47
    • 0024564204 scopus 로고
    • A branched, synthetic octapeptide of ubiquitinated histone h2a as target of autoantibodies
    • Plaue S, Muller S, van Regenmortel MH. A branched, synthetic octapeptide of ubiquitinated histone H2A as target of autoantibodies. J Exp Med 1989; 169: 1607-1617
    • (1989) J Exp Med , vol.169 , pp. 1607-1617
    • Plaue, S.1    Muller, S.2    Van Regenmortel, M.H.3
  • 49
    • 78650626621 scopus 로고    scopus 로고
    • Rfx1 regulates cd70 and cd11a expression in lupus t cells by recruiting the histone methyltransferase suv39h1
    • Zhao M, Wu X, Zhang Q, Luo S, Liang G, Su Y et al. RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1. Arthritis Res Ther 2010; 12: R227
    • (2010) Arthritis Res Ther , vol.12 , pp. R227
    • Zhao, M.1    Wu, X.2    Zhang, Q.3    Luo, S.4    Liang, G.5    Su, Y.6
  • 50
    • 79952779639 scopus 로고    scopus 로고
    • Microrna, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases
    • Dai R, Ahmed SA. MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases. Transl Res 2011; 157: 163-179
    • (2011) Transl Res , vol.157 , pp. 163-179
    • Dai, R.1    Ahmed, S.A.2
  • 51
    • 79955569628 scopus 로고    scopus 로고
    • Microrna-126 regulates dna methylation in cd4+ t cells and contributes to systemic lupus erythematosus by targeting dna methyltransferase 1
    • Zhao S, Wang Y, Liang Y, Zhao M, Long H, Ding S et al. MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum 2011; 63: 1376-1386
    • (2011) Arthritis Rheum , vol.63 , pp. 1376-1386
    • Zhao, S.1    Wang, Y.2    Liang, Y.3    Zhao, M.4    Long, H.5    Ding, S.6
  • 52
    • 77953624215 scopus 로고    scopus 로고
    • Microrna-21 and microrna-148a contribute to dna hypomethylation in lupus cd4+ t cells by directly and indirectly targeting dna methyltransferase 1
    • Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo X et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol 2010; 184: 6773-6781
    • (2010) J Immunol , vol.184 , pp. 6773-6781
    • Pan, W.1    Zhu, S.2    Yuan, M.3    Cui, H.4    Wang, L.5    Luo, X.6
  • 53
    • 84870531924 scopus 로고    scopus 로고
    • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
    • Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet 44: 1336-13402012
    • Nat Genet , vol.44 , pp. 1336-13402012
    • Eyre, S.1    Bowes, J.2    Diogo, D.3    Lee, A.4    Barton, A.5    Martin, P.6
  • 55
    • 84863189550 scopus 로고    scopus 로고
    • Camp response elementbinding (creb) recruitment following a specific cpg demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis
    • Bui C, Barter MJ, Scott JL, Xu Y, Galler M, Reynard LN et al. cAMP response elementbinding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. FASEB J 2012; 26: 3000-3011
    • (2012) FASEB J , vol.26 , pp. 3000-3011
    • Bui, C.1    Barter, M.J.2    Scott, J.L.3    Xu, Y.4    Galler, M.5    Reynard, L.N.6
  • 56
    • 84863395477 scopus 로고    scopus 로고
    • Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients
    • Gillespie J, Savic S, Wong C, Hempshall A, Inman M, Emery P et al. Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Rheum 2012; 64: 418-422
    • (2012) Arthritis Rheum , vol.64 , pp. 418-422
    • Gillespie, J.1    Savic, S.2    Wong, C.3    Hempshall, A.4    Inman, M.5    Emery, P.6
  • 57
    • 34247227700 scopus 로고    scopus 로고
    • Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients
    • Huber LC, Brock M, Hemmatazad H, Giger OT, Moritz F, Trenkmann M et al. Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients. Arthritis Rheum 2007; 56: 1087-1093
    • (2007) Arthritis Rheum , vol.56 , pp. 1087-1093
    • Huber, L.C.1    Brock, M.2    Hemmatazad, H.3    Giger, O.T.4    Moritz, F.5    Trenkmann, M.6
  • 58
    • 84874961094 scopus 로고    scopus 로고
    • Perspectives on epigenetic-based immune intervention for rheumatic diseases
    • Gray SG. Perspectives on epigenetic-based immune intervention for rheumatic diseases. Arthritis Res Ther 2013; 15: 207
    • (2013) Arthritis Res Ther , vol.15 , pp. 207
    • Gray, S.G.1
  • 62
    • 67650169908 scopus 로고    scopus 로고
    • Biological functions of mir-29b contribute to positive regulation of osteoblast differentiation
    • Li Z, Hassan MQ, Jafferji M, Aqeilan RI, Garzon R, Croce CM et al. Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem 2009; 284: 15676-15684
    • (2009) J Biol Chem , vol.284 , pp. 15676-15684
    • Li, Z.1    Hassan, M.Q.2    Jafferji, M.3    Aqeilan, R.I.4    Garzon, R.5    Croce, C.M.6
  • 63
    • 79960391940 scopus 로고    scopus 로고
    • Mir-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells
    • Eades G, Yao Y, Yang M, Zhang Y, Chumsri S, Zhou Q. miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells. J Biol Chem 2011; 286: 25992-26002
    • (2011) J Biol Chem , vol.286 , pp. 25992-26002
    • Eades, G.1    Yao, Y.2    Yang, M.3    Zhang, Y.4    Chumsri, S.5    Zhou, Q.6
  • 65
    • 58049204426 scopus 로고    scopus 로고
    • Epigenetics in multiple sclerosis susceptibility: Difference in transgenerational risk localizes to the major histocompatibility complex
    • Chao MJ, Ramagopalan SV, Herrera BM, Lincoln MR, Dyment DA, Sadovnick AD et al. Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex. Hum Mol Genet 2009; 18: 261-266
    • (2009) Hum Mol Genet , vol.18 , pp. 261-266
    • Chao, M.J.1    Ramagopalan, S.V.2    Herrera, B.M.3    Lincoln, M.R.4    Dyment, D.A.5    Sadovnick, A.D.6
  • 67
    • 34447334574 scopus 로고    scopus 로고
    • Peptidyl argininedeiminase 2 cpg island in multiple sclerosis white matter is hypomethylated
    • Mastronardi FG, Noor A, Wood DD, Paton T, Moscarello MA. Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J Neurosci Res 2007; 85: 2006-2016
    • (2007) J Neurosci Res , vol.85 , pp. 2006-2016
    • Mastronardi, F.G.1    Noor, A.2    Wood, D.D.3    Paton, T.4    Moscarello, M.A.5
  • 68
    • 79952272438 scopus 로고    scopus 로고
    • Changed histone acetylation patterns in normal-Appearing white matter and early multiple sclerosis lesions
    • Pedre X, Mastronardi F, Bruck W, López-Rodas G, Kuhlmann T, Casaccia P. Changed histone acetylation patterns in normal-Appearing white matter and early multiple sclerosis lesions. J Neurosci 2011; 31: 3435-3445
    • (2011) J Neurosci , vol.31 , pp. 3435-3445
    • Pedre, X.1    Mastronardi, F.2    Bruck, W.3    López-Rodas, G.4    Kuhlmann, T.5    Casaccia, P.6
  • 71
    • 80053457972 scopus 로고    scopus 로고
    • Identification of type 1 diabetes-Associated dna methylation variable positions that precede disease diagnosis
    • Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D et al. Identification of type 1 diabetes-Associated DNA methylation variable positions that precede disease diagnosis. PLoS Genet 2011; 7: e1002300
    • (2011) PLoS Genet , vol.7 , pp. e1002300
    • Rakyan, V.K.1    Beyan, H.2    Down, T.A.3    Hawa, M.I.4    Maslau, S.5    Aden, D.6
  • 72
    • 84898787481 scopus 로고    scopus 로고
    • Dna methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology
    • Stefan M, Zhang W, Concepcion E, Yi Z, Tomer Y. DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology. J Autoimmun 2014; 50: 33-37
    • (2014) J Autoimmun , vol.50 , pp. 33-37
    • Stefan, M.1    Zhang, W.2    Concepcion, E.3    Yi, Z.4    Tomer, Y.5
  • 73
    • 77953808473 scopus 로고    scopus 로고
    • Next-generation genomics: An integrative approach
    • Hawkins RD, Hon GC, Ren B. Next-generation genomics: an integrative approach. Nat Rev Genet 2010; 11: 476-486
    • (2010) Nat Rev Genet , vol.11 , pp. 476-486
    • Hawkins, R.D.1    Hon, G.C.2    Ren, B.3
  • 74
    • 84865822182 scopus 로고    scopus 로고
    • Systematic localization of common disease-Associated variation in regulatory dna
    • Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H et al. Systematic localization of common disease-Associated variation in regulatory DNA. Science 2012; 337: 1190-1195
    • (2012) Science , vol.337 , pp. 1190-1195
    • Maurano, M.T.1    Humbert, R.2    Rynes, E.3    Thurman, R.E.4    Haugen, E.5    Wang, H.6
  • 75
    • 84861391922 scopus 로고    scopus 로고
    • Dna methylation screening identifies driver epigenetic events of cancer cell survival
    • De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK et al. DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell 2012; 21: 655-667
    • (2012) Cancer Cell , vol.21 , pp. 655-667
    • De Carvalho, D.D.1    Sharma, S.2    You, J.S.3    Su, S.F.4    Taberlay, P.C.5    Kelly, T.K.6
  • 76
    • 79960556965 scopus 로고    scopus 로고
    • Epigenome-wide association studies for common human diseases
    • Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome-wide association studies for common human diseases. Nat Rev Genet 2011; 12: 529-541
    • (2011) Nat Rev Genet , vol.12 , pp. 529-541
    • Rakyan, V.K.1    Down, T.A.2    Balding, D.J.3    Beck, S.4
  • 77
    • 80053896562 scopus 로고    scopus 로고
    • Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets
    • Hu X, Kim H, Stahl E, Plenge R, Daly M, Raychaudhuri S. Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets. Am J Hum Genet 2011; 89: 496-506
    • (2011) Am J Hum Genet , vol.89 , pp. 496-506
    • Hu, X.1    Kim, H.2    Stahl, E.3    Plenge, R.4    Daly, M.5    Raychaudhuri, S.6
  • 78
    • 84882449068 scopus 로고    scopus 로고
    • Genetic insights into common pathways and complex relationships among immune-mediated diseases
    • Parkes M, Cortes A, van Heel DA, Brown MA. Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet 2013; 14: 661-673
    • (2013) Nat Rev Genet , vol.14 , pp. 661-673
    • Parkes, M.1    Cortes, A.2    Van Heel, D.A.3    Brown, M.A.4
  • 79
    • 84874721851 scopus 로고    scopus 로고
    • Genetics and epigenetics of rheumatoid arthritis
    • Viatte S, Plant D, Raychaudhuri S. Genetics and epigenetics of rheumatoid arthritis. Nat Rev Rheumatol 2013; 9: 141-153
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 141-153
    • Viatte, S.1    Plant, D.2    Raychaudhuri, S.3
  • 80
    • 84873576566 scopus 로고    scopus 로고
    • Epigenomewide association data implicate dna methylation as an intermediary of genetic risk in rheumatoid arthritis
    • Liu Y, Aryee MJ, Padyukov L, Fallin MD, Hesselberg E, Runarsson A et al. Epigenomewide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol 2013; 31: 142-147
    • (2013) Nat Biotechnol , vol.31 , pp. 142-147
    • Liu, Y.1    Aryee, M.J.2    Padyukov, L.3    Fallin, M.D.4    Hesselberg, E.5    Runarsson, A.6
  • 81
    • 84355163093 scopus 로고    scopus 로고
    • Dna-binding factors shape the mouse methylome at distal regulatory regions
    • Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, Schöler A et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 2011; 480: 490-495
    • (2011) Nature , vol.480 , pp. 490-495
    • Stadler, M.B.1    Murr, R.2    Burger, L.3    Ivanek, R.4    Lienert, F.5    Schöler, A.6
  • 82
    • 84885021247 scopus 로고    scopus 로고
    • Epigenetic memory at embryonic enhancers identified in dna methylation maps from adult mouse tissues
    • Hon GC, Rajagopal N, Shen Y, McCleary DF, Yue F, Dang MD et al. Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat Genet 2013; 45: 1198-1206
    • (2013) Nat Genet , vol.45 , pp. 1198-1206
    • Hon, G.C.1    Rajagopal, N.2    Shen, Y.3    McCleary, D.F.4    Yue, F.5    Dang, M.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.