메뉴 건너뛰기




Volumn 127, Issue 3, 2008, Pages 366-374

Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens

Author keywords

Autoantibodies; Autoantigens; GAD65; IA 2; Protein tyrosine phosphatase; Proteome; Secretory vesicles; Type 1 diabetes

Indexed keywords

ALPHA FODRIN; AMPHIPHYSIN; AUTOANTIBODY; AUTOANTIGEN; BETA1 INTEGRIN; BETA2 SYNTROPHIN; CARBOXYPEPTIDASE; CHROMOGRANIN A; FURIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOKINASE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE TRANSPORTER 4; GLUTAMATE DECARBOXYLASE 65; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 70; INSULIN; NEUROPEPTIDE Y; PADGEM PROTEIN; PROTEIN IA 2; PROTEIN IA 2BETA; PROTEIN TYROSINE PHOSPHATASE ALPHA; PROTEOME; RAB11 PROTEIN; SYNAPTOBREVIN 2; SYNTAXIN 1A; SYNTAXIN 3A; SYNTAXIN 6; TRANSCRIPTION FACTOR JUNB; UNINDEXED DRUG;

EID: 45249111131     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2008.01.018     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 19244366132 scopus 로고    scopus 로고
    • Notkins A.L., Lernmark A., and Leslie D. (Eds)
    • In: Notkins A.L., Lernmark A., and Leslie D. (Eds). Autoantibodies as Diagnostic and Predictive Markers of Autoimmune Diseases. Autoimmunity 37 (2004) 251-368
    • (2004) Autoimmunity , vol.37 , pp. 251-368
  • 2
    • 20444505232 scopus 로고    scopus 로고
    • An array of possibilities for the study of autoimmunity
    • Fathman C.G., Soares L., Chan S.M., and Utz P.J. An array of possibilities for the study of autoimmunity. Nature 435 (2005) 605-611
    • (2005) Nature , vol.435 , pp. 605-611
    • Fathman, C.G.1    Soares, L.2    Chan, S.M.3    Utz, P.J.4
  • 3
    • 0029975769 scopus 로고    scopus 로고
    • IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus
    • Lan M.S., Wasserfall C., Maclaren N.K., and Notkins A.L. IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 6367-6370
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 6367-6370
    • Lan, M.S.1    Wasserfall, C.2    Maclaren, N.K.3    Notkins, A.L.4
  • 5
    • 0034652317 scopus 로고    scopus 로고
    • Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes
    • Yu L., Robles D.T., Abiru N., Kaur P., Rewers M., Kelemen K., and Eisenbarth G.S. Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 1701-1706
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 1701-1706
    • Yu, L.1    Robles, D.T.2    Abiru, N.3    Kaur, P.4    Rewers, M.5    Kelemen, K.6    Eisenbarth, G.S.7
  • 6
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
    • Verge C.F., Gianani R., Kawasaki E., Yu L., Pietropaolo M., Jackson R.A., Chase H.P., and Eisenbarth G.S. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes 45 (1996) 926-933
    • (1996) Diabetes , vol.45 , pp. 926-933
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3    Yu, L.4    Pietropaolo, M.5    Jackson, R.A.6    Chase, H.P.7    Eisenbarth, G.S.8
  • 7
    • 0030695027 scopus 로고    scopus 로고
    • Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers
    • Bingley P.J., Bonifacio E., Williams A.J., Genovese S., Bottazzo G.F., and Gale E.A. Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers. Diabetes 46 (1997) 1701-1710
    • (1997) Diabetes , vol.46 , pp. 1701-1710
    • Bingley, P.J.1    Bonifacio, E.2    Williams, A.J.3    Genovese, S.4    Bottazzo, G.F.5    Gale, E.A.6
  • 8
    • 0032518421 scopus 로고    scopus 로고
    • Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group
    • Kulmala P., Savola K., Petersen J.S., Vahasalo P., Karjalainen J., Lopponen T., Dyrberg T., Akerblom H.K., and Knip M. Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group. J. Clin. Invest. 101 (1998) 327-336
    • (1998) J. Clin. Invest. , vol.101 , pp. 327-336
    • Kulmala, P.1    Savola, K.2    Petersen, J.S.3    Vahasalo, P.4    Karjalainen, J.5    Lopponen, T.6    Dyrberg, T.7    Akerblom, H.K.8    Knip, M.9
  • 9
    • 0029927890 scopus 로고    scopus 로고
    • Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment
    • Lu J., Li Q., Xie H., Chen Z.J., Borovitskaya A.E., Maclaren N.K., Notkins A.L., and Lan M.S. Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 2307-2311
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 2307-2311
    • Lu, J.1    Li, Q.2    Xie, H.3    Chen, Z.J.4    Borovitskaya, A.E.5    Maclaren, N.K.6    Notkins, A.L.7    Lan, M.S.8
  • 10
    • 0031252267 scopus 로고    scopus 로고
    • Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined
    • Xie H., Zhang B., Matsumoto Y., Li Q., Notkins A.L., and Lan M.S. Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined. J. Immunol. 159 (1997) 3662-3667
    • (1997) J. Immunol. , vol.159 , pp. 3662-3667
    • Xie, H.1    Zhang, B.2    Matsumoto, Y.3    Li, Q.4    Notkins, A.L.5    Lan, M.S.6
  • 14
    • 0035040092 scopus 로고    scopus 로고
    • Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13
    • Fida S., Myers M., Mackay I.R., Zimmet P.Z., Mohan V., Deepa R., and Rowley M.J. Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13. Diabetes Res. Clin. Pract. 52 (2001) 205-211
    • (2001) Diabetes Res. Clin. Pract. , vol.52 , pp. 205-211
    • Fida, S.1    Myers, M.2    Mackay, I.R.3    Zimmet, P.Z.4    Mohan, V.5    Deepa, R.6    Rowley, M.J.7
  • 16
    • 3042763965 scopus 로고    scopus 로고
    • Autoantibodies against IA-2, GAD, and topoisomerase II in type 1 diabetic patients
    • Chang Y.H., Shiau M.Y., Tsai S.T., and Lan M.S. Autoantibodies against IA-2, GAD, and topoisomerase II in type 1 diabetic patients. Biochem. Biophys. Res. Commun. 320 (2004) 802-809
    • (2004) Biochem. Biophys. Res. Commun. , vol.320 , pp. 802-809
    • Chang, Y.H.1    Shiau, M.Y.2    Tsai, S.T.3    Lan, M.S.4
  • 17
    • 0030026955 scopus 로고    scopus 로고
    • Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient
    • Arden S.D., Roep B.O., Neophytou P.I., Usac E.F., Duinkerken G., de Vries R.R., and Hutton J.C. Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient. J. Clin. Invest. 97 (1996) 551-561
    • (1996) J. Clin. Invest. , vol.97 , pp. 551-561
    • Arden, S.D.1    Roep, B.O.2    Neophytou, P.I.3    Usac, E.F.4    Duinkerken, G.5    de Vries, R.R.6    Hutton, J.C.7
  • 20
    • 0027070567 scopus 로고
    • A 64 kDa antigen/glutamic acid decarboxylase (GAD) in fetal pig pro-islets: co-precipitation with a 38 kDa protein and recognition by T cells in humans at risk for insulin-dependent diabetes
    • DeAizpurua H.J., Honeyman M.C., and Harrison L.C. A 64 kDa antigen/glutamic acid decarboxylase (GAD) in fetal pig pro-islets: co-precipitation with a 38 kDa protein and recognition by T cells in humans at risk for insulin-dependent diabetes. J. Autoimmun. 5 (1992) 759-770
    • (1992) J. Autoimmun. , vol.5 , pp. 759-770
    • DeAizpurua, H.J.1    Honeyman, M.C.2    Harrison, L.C.3
  • 21
    • 0027502526 scopus 로고
    • Transcription factor jun-B is target of autoreactive T-cells in IDDM
    • Honeyman M.C., Cram D.S., and Harrison L.C. Transcription factor jun-B is target of autoreactive T-cells in IDDM. Diabetes 42 (1993) 626-630
    • (1993) Diabetes , vol.42 , pp. 626-630
    • Honeyman, M.C.1    Cram, D.S.2    Harrison, L.C.3
  • 22
    • 0030051666 scopus 로고    scopus 로고
    • HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus
    • Roep B.O., Duinkerken G., Schreuder G.M., Kolb H., de Vries R.R., and Martin S. HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus. Eur. J. Immunol. 26 (1996) 1285-1289
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1285-1289
    • Roep, B.O.1    Duinkerken, G.2    Schreuder, G.M.3    Kolb, H.4    de Vries, R.R.5    Martin, S.6
  • 23
    • 0038617504 scopus 로고    scopus 로고
    • T cells and autoantibodies to human HSP70 in type 1 diabetes in children
    • Abulafia-Lapid R., Gillis D., Yosef O., Atlan H., and Cohen I.R. T cells and autoantibodies to human HSP70 in type 1 diabetes in children. J. Autoimmun. 20 (2003) 313-321
    • (2003) J. Autoimmun. , vol.20 , pp. 313-321
    • Abulafia-Lapid, R.1    Gillis, D.2    Yosef, O.3    Atlan, H.4    Cohen, I.R.5
  • 26
    • 0031740737 scopus 로고    scopus 로고
    • Vesicular autoantigens of type 1 diabetes
    • Solimena M. Vesicular autoantigens of type 1 diabetes. Diabetes Metab. Rev. 14 (1998) 227-240
    • (1998) Diabetes Metab. Rev. , vol.14 , pp. 227-240
    • Solimena, M.1
  • 27
    • 0033743268 scopus 로고    scopus 로고
    • Autoantibodies in recent onset type-1 diabetic patients to a Mr 60K microsomal hepatic protein: new evidence for autoantibodies to the type-2 glucose transporter
    • Pehuet-Figoni M., Alvarez F., Bach J.F., and Chatenoud L. Autoantibodies in recent onset type-1 diabetic patients to a Mr 60K microsomal hepatic protein: new evidence for autoantibodies to the type-2 glucose transporter. Clin. Exp. Immunol. 122 (2000) 164-169
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 164-169
    • Pehuet-Figoni, M.1    Alvarez, F.2    Bach, J.F.3    Chatenoud, L.4
  • 28
    • 0035403063 scopus 로고    scopus 로고
    • Belgian Diabetes Registry, Autoantibodies to a 38-kDa glycosylated islet cell membrane-associated antigen in (pre)type 1 diabetes: association with IA-2 and islet cell autoantibodies
    • Winnock F., Christie M.R., Batstra M.R., Aanstoot H.J., Weets I., Decochez K., Jopart P., Nicolaij D., and Gorus F.K. Belgian Diabetes Registry, Autoantibodies to a 38-kDa glycosylated islet cell membrane-associated antigen in (pre)type 1 diabetes: association with IA-2 and islet cell autoantibodies. Diabetes Care 24 (2001) 1181-1186
    • (2001) Diabetes Care , vol.24 , pp. 1181-1186
    • Winnock, F.1    Christie, M.R.2    Batstra, M.R.3    Aanstoot, H.J.4    Weets, I.5    Decochez, K.6    Jopart, P.7    Nicolaij, D.8    Gorus, F.K.9
  • 29
    • 12244250794 scopus 로고    scopus 로고
    • Patients with insulin-dependent diabetes but not those with non-insulin-dependent diabetes have anti-sulfatide antibodies as determined with a new ELISA assay
    • Andersson K., Buschard K., Fredman P., Kaas A., Lidstrom A.M., Madsbad S., Mortensen H., and Jan-Eric M. Patients with insulin-dependent diabetes but not those with non-insulin-dependent diabetes have anti-sulfatide antibodies as determined with a new ELISA assay. Autoimmunity 35 (2002) 463-468
    • (2002) Autoimmunity , vol.35 , pp. 463-468
    • Andersson, K.1    Buschard, K.2    Fredman, P.3    Kaas, A.4    Lidstrom, A.M.5    Madsbad, S.6    Mortensen, H.7    Jan-Eric, M.8
  • 31
    • 30044433222 scopus 로고    scopus 로고
    • No evidence of diabetes-specific CD38 (ADP ribosil cyclase/cyclic ADP-ribose hydrolase) autoantibodies by liquid-phase immunoprecipitation
    • Sordi V., Lampasona V., Cainarca S., and Bonifacio E. No evidence of diabetes-specific CD38 (ADP ribosil cyclase/cyclic ADP-ribose hydrolase) autoantibodies by liquid-phase immunoprecipitation. Diabet. Med. 22 (2005) 1770-1773
    • (2005) Diabet. Med. , vol.22 , pp. 1770-1773
    • Sordi, V.1    Lampasona, V.2    Cainarca, S.3    Bonifacio, E.4
  • 32
    • 0026709532 scopus 로고
    • Detection of autoantibodies against islet amyloid polypeptide in human serum. Lack of association with type 1 (insulin-dependent) diabetes mellitus, or with conditions favouring amyloid deposition in islets. The Belgian Diabetes Registry
    • Gorus F.K., Sodoyez J.C., Pipeleers D.G., Keymeulen B., Foriers A., and Van Schravendijk C.F. Detection of autoantibodies against islet amyloid polypeptide in human serum. Lack of association with type 1 (insulin-dependent) diabetes mellitus, or with conditions favouring amyloid deposition in islets. The Belgian Diabetes Registry. Diabetologia 35 (1992) 1080-1086
    • (1992) Diabetologia , vol.35 , pp. 1080-1086
    • Gorus, F.K.1    Sodoyez, J.C.2    Pipeleers, D.G.3    Keymeulen, B.4    Foriers, A.5    Van Schravendijk, C.F.6
  • 33
    • 0024366008 scopus 로고
    • Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain
    • Baumert M., Maycox P.R., Navone F., De Camilli P., and Jahn R. Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain. EMBO J. 8 (1989) 379-384
    • (1989) EMBO J. , vol.8 , pp. 379-384
    • Baumert, M.1    Maycox, P.R.2    Navone, F.3    De Camilli, P.4    Jahn, R.5
  • 38
    • 0023128259 scopus 로고
    • Multiple immunological abnormalities in patients with type 1 (insulin-dependent) diabetes mellitus
    • Drell D.W., and Notkins A.L. Multiple immunological abnormalities in patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia 30 (1987) 132-143
    • (1987) Diabetologia , vol.30 , pp. 132-143
    • Drell, D.W.1    Notkins, A.L.2
  • 39
    • 0242364727 scopus 로고    scopus 로고
    • A comprehensive guide to antibody and T-cell responses in type 1 diabetes
    • Lieberman S.M., and DiLorenzo T.P. A comprehensive guide to antibody and T-cell responses in type 1 diabetes. Tissue Antigens 62 (2003) 359-377
    • (2003) Tissue Antigens , vol.62 , pp. 359-377
    • Lieberman, S.M.1    DiLorenzo, T.P.2
  • 40
    • 0034765129 scopus 로고    scopus 로고
    • Islet cell antibodies represent autoimmune response against several antigens
    • Mansson L., Torn C., and Landin-Olsson M. Islet cell antibodies represent autoimmune response against several antigens. Int. J. Exp. Diabetes Res. 2 (2001) 85-90
    • (2001) Int. J. Exp. Diabetes Res. , vol.2 , pp. 85-90
    • Mansson, L.1    Torn, C.2    Landin-Olsson, M.3
  • 41
    • 0031438330 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase-like protein IA2-antibodies plus glutamic acid decarboxylase 65 antibodies (GADA) indicates autoimmunity as frequently as islet cell antibodies assay in children with recently diagnosed diabetes mellitus
    • Borg H., Fernlund P., and Sundkvist G. Protein tyrosine phosphatase-like protein IA2-antibodies plus glutamic acid decarboxylase 65 antibodies (GADA) indicates autoimmunity as frequently as islet cell antibodies assay in children with recently diagnosed diabetes mellitus. Clin. Chem. 43 (1997) 2358-2363
    • (1997) Clin. Chem. , vol.43 , pp. 2358-2363
    • Borg, H.1    Fernlund, P.2    Sundkvist, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.