Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility

Diabetes

Volumn 63, Issue 7, 2014, Pages 2402-2414

  Kallionpää, Henna ^a,b,c   Elo, Laura L ^a,d   Laajala, Essi ^a,c,e,f   Mykkänen, Juha ^a,c,d,g   Ricaño Ponce, Isis ^h   Vaarma, Matti ⁱ   Laajala, Teemu D ^a   Hyöty, Heikki ^i,j   Ilonen, Jorma ^d,k   Veijola, Riitta ^l   Simell, Tuula ^c,d   Wijmenga, Cisca ^h   Knip, Mikael ^c,m,n,o   Lähdesmäki, Harri ^a,c,e   Simell, Olli ^c,d,g   Lahesmaa, Riitta ^a,c  

^a TURKU CENTRE FOR BIOTECHNOLOGY   (Finland)

^b Turku Doctoral Programme of Biomedical Sciences   (Finland)

^c Finnish Centre of Excellence in Molecular Systems Immunology and Physiology Research   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e AALTO UNIVERSITY   (Finland)

^f National Graduate School in Informational and Structural Biology   (Finland)

^g TURKU UNIVERSITY HOSPITAL   (Finland)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^j PIRKANMAA HOSPITAL DISTRICT   (Finland)

^k UNIVERSITY OF EASTERN FINLAND   (Finland)

^l UNIVERSITY OF OULU   (Finland)

^m UNIVERSITY OF HELSINKI   (Finland)

ⁿ FOLKHÄLSAN RESEARCH CENTER   (Finland)

^o TAMPERE UNIVERSITY HOSPITAL   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; HLA DQB1 ANTIGEN; INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 2; INTERFERON REGULATORY FACTOR 7; RETINOID X RECEPTOR ALPHA; RNA; STAT1 PROTEIN; STAT2 PROTEIN;

ANTIBODY DETECTION; ARTICLE; BIRTH; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE COURSE; FINLAND; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEROCONVERSION; SEX; TIME; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS;

ADOLESCENT; AUTOANTIBODIES; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-DQ BETA-CHAINS; HUMANS; IMMUNITY, INNATE; MALE; MICROARRAY ANALYSIS; TRANSCRIPTOME;

EID: 84903184518     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1775     Document Type: Article

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