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Volumn 36, Issue , 2017, Pages 117-124

HIV-associated cellular senescence: A contributor to accelerated aging

Author keywords

HAART; HIV; HIV comorbidities; Premature aging; Senescence; Substance abuse

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT;

EID: 85017562243     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2016.12.004     Document Type: Review
Times cited : (60)

References (107)
  • 3
    • 84951761244 scopus 로고    scopus 로고
    • LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: role of ZMPSTE24 downregulation
    • Afonso, P., Auclair, M., Boccara, F., Vantyghem, M.C., Katlama, C., Capeau, J., Vigouroux, C., Caron-Debarle, M., LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: role of ZMPSTE24 downregulation. Atherosclerosis 245 (2015), 200–211.
    • (2015) Atherosclerosis , vol.245 , pp. 200-211
    • Afonso, P.1    Auclair, M.2    Boccara, F.3    Vantyghem, M.C.4    Katlama, C.5    Capeau, J.6    Vigouroux, C.7    Caron-Debarle, M.8
  • 4
    • 84940404091 scopus 로고    scopus 로고
    • Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease
    • Ahmad, T., Sundar, I.K., Lerner, C.A., Gerloff, J., Tormos, A.M., Yao, H., Rahman, I., Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB J. 29 (2015), 2912–2929.
    • (2015) FASEB J. , vol.29 , pp. 2912-2929
    • Ahmad, T.1    Sundar, I.K.2    Lerner, C.A.3    Gerloff, J.4    Tormos, A.M.5    Yao, H.6    Rahman, I.7
  • 6
    • 84865165486 scopus 로고    scopus 로고
    • Effects of chronic cocaine in rat C6 astroglial cells
    • Badisa, R.B., Goodman, C.B., Effects of chronic cocaine in rat C6 astroglial cells. Int. J. Mol. Med. 30 (2012), 687–692.
    • (2012) Int. J. Mol. Med. , vol.30 , pp. 687-692
    • Badisa, R.B.1    Goodman, C.B.2
  • 7
    • 84876998223 scopus 로고    scopus 로고
    • p21 Both attenuates and drives senescence and aging in BubR1 progeroid mice
    • Baker, D.J., Weaver, R.L., van Deursen, J.M., p21 Both attenuates and drives senescence and aging in BubR1 progeroid mice. Cell Rep. 3 (2013), 1164–1174.
    • (2013) Cell Rep. , vol.3 , pp. 1164-1174
    • Baker, D.J.1    Weaver, R.L.2    van Deursen, J.M.3
  • 9
    • 85012045987 scopus 로고    scopus 로고
    • The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation
    • Beaupere, C., Garcia, M., Larghero, J., Feve, B., Capeau, J., Lagathu, C., The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation. Aging Cell 14 (2015), 534–546.
    • (2015) Aging Cell , vol.14 , pp. 534-546
    • Beaupere, C.1    Garcia, M.2    Larghero, J.3    Feve, B.4    Capeau, J.5    Lagathu, C.6
  • 11
    • 84863671863 scopus 로고    scopus 로고
    • Accelerated aging and human immunodeficiency virus infection: emerging challenges of growing older in the era of successful antiretroviral therapy
    • Bhatia, R., Ryscavage, P., Taiwo, B., Accelerated aging and human immunodeficiency virus infection: emerging challenges of growing older in the era of successful antiretroviral therapy. J. Neurovirol. 18 (2012), 247–255.
    • (2012) J. Neurovirol. , vol.18 , pp. 247-255
    • Bhatia, R.1    Ryscavage, P.2    Taiwo, B.3
  • 14
    • 0027370209 scopus 로고
    • CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration
    • Brady, H.J., Pennington, D.J., Miles, C.G., Dzierzak, E.A., CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration. EMBO J. 12 (1993), 4923–4932.
    • (1993) EMBO J. , vol.12 , pp. 4923-4932
    • Brady, H.J.1    Pennington, D.J.2    Miles, C.G.3    Dzierzak, E.A.4
  • 15
    • 33645116573 scopus 로고    scopus 로고
    • HIV entry inhibitors: mechanisms of action and resistance pathways
    • Briz, V., Poveda, E., Soriano, V., HIV entry inhibitors: mechanisms of action and resistance pathways. J. Antimicrob. Chemother. 57 (2006), 619–627.
    • (2006) J. Antimicrob. Chemother. , vol.57 , pp. 619-627
    • Briz, V.1    Poveda, E.2    Soriano, V.3
  • 16
    • 80855128461 scopus 로고    scopus 로고
    • Cellular senescence: a link between cancer and age-related degenerative disease?
    • Campisi, J., Andersen, J.K., Kapahi, P., Melov, S., Cellular senescence: a link between cancer and age-related degenerative disease?. Semin. Cancer Biol. 21 (2011), 354–359.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 354-359
    • Campisi, J.1    Andersen, J.K.2    Kapahi, P.3    Melov, S.4
  • 17
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • Campisi, J., Aging, cellular senescence, and cancer. Annu. Rev. Physiol. 75 (2013), 685–705.
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 685-705
    • Campisi, J.1
  • 18
    • 1042263432 scopus 로고    scopus 로고
    • Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation
    • Caron, M., Auclair, M., Sterlingot, H., Kornprobst, M., Capeau, J., Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation. AIDS 17 (2003), 2437–2444.
    • (2003) AIDS , vol.17 , pp. 2437-2444
    • Caron, M.1    Auclair, M.2    Sterlingot, H.3    Kornprobst, M.4    Capeau, J.5
  • 19
    • 34548713556 scopus 로고    scopus 로고
    • Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence
    • Caron, M., Auclair, M., Donadille, B., Bereziat, V., Guerci, B., Laville, M., Narbonne, H., Bodemer, C., Lascols, O., Capeau, J., Vigouroux, C., Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence. Cell Death Differ. 14 (2007), 1759–1767.
    • (2007) Cell Death Differ. , vol.14 , pp. 1759-1767
    • Caron, M.1    Auclair, M.2    Donadille, B.3    Bereziat, V.4    Guerci, B.5    Laville, M.6    Narbonne, H.7    Bodemer, C.8    Lascols, O.9    Capeau, J.10    Vigouroux, C.11
  • 20
    • 42149172274 scopus 로고    scopus 로고
    • Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues
    • Caron, M., Auclairt, M., Vissian, A., Vigouroux, C., Capeau, J., Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues. Antivir. Ther. 13 (2008), 27–38.
    • (2008) Antivir. Ther. , vol.13 , pp. 27-38
    • Caron, M.1    Auclairt, M.2    Vissian, A.3    Vigouroux, C.4    Capeau, J.5
  • 21
    • 34547810854 scopus 로고    scopus 로고
    • Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model
    • Chang, S.L., Beltran, J.A., Swarup, S., Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model. J. Virol. 81 (2007), 8406–8411.
    • (2007) J. Virol. , vol.81 , pp. 8406-8411
    • Chang, S.L.1    Beltran, J.A.2    Swarup, S.3
  • 24
    • 84878085003 scopus 로고    scopus 로고
    • Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells
    • Chou, J.P., Ramirez, C.M., Wu, J.E., Effros, R.B., Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells. PLoS One, 8, 2013, e64702.
    • (2013) PLoS One , vol.8 , pp. e64702
    • Chou, J.P.1    Ramirez, C.M.2    Wu, J.E.3    Effros, R.B.4
  • 25
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins, K.L., Chen, B.K., Kalams, S.A., Walker, B.D., Baltimore, D., HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391 (1998), 397–401.
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1    Chen, B.K.2    Kalams, S.A.3    Walker, B.D.4    Baltimore, D.5
  • 26
    • 84891713034 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
    • Coppe, J.P., Patil, C.K., Rodier, F., Sun, Y., Munoz, D.P., Goldstein, J., Nelson, P.S., Desprez, P.Y., Campisi, J., Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6 (2008), 2853–2868.
    • (2008) PLoS Biol. , vol.6 , pp. 2853-2868
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3    Sun, Y.4    Munoz, D.P.5    Goldstein, J.6    Nelson, P.S.7    Desprez, P.Y.8    Campisi, J.9
  • 29
    • 80052452885 scopus 로고    scopus 로고
    • The HIV-1 Tat protein has a versatile role in activating viral transcription
    • Das, A.T., Harwig, A., Berkhout, B., The HIV-1 Tat protein has a versatile role in activating viral transcription. J. Virol. 85 (2011), 9506–9516.
    • (2011) J. Virol. , vol.85 , pp. 9506-9516
    • Das, A.T.1    Harwig, A.2    Berkhout, B.3
  • 31
    • 67649639637 scopus 로고    scopus 로고
    • Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV-1 infected naive patients
    • Duvivier, C., Kolta, S., Assoumou, L., Ghosn, J., Rozenberg, S., Murphy, R.L., Katlama, C., Costagliola, D., group, A.H.s., Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV-1 infected naive patients. AIDS 23 (2009), 817–824.
    • (2009) AIDS , vol.23 , pp. 817-824
    • Duvivier, C.1    Kolta, S.2    Assoumou, L.3    Ghosn, J.4    Rozenberg, S.5    Murphy, R.L.6    Katlama, C.7    Costagliola, D.8    group, A.H.S.9
  • 33
    • 84886036984 scopus 로고    scopus 로고
    • Differential responses of human hepatocytes to the non-nucleoside HIV-1 reverse transcriptase inhibitor nevirapine
    • Fang, J.L., Beland, F.A., Differential responses of human hepatocytes to the non-nucleoside HIV-1 reverse transcriptase inhibitor nevirapine. J. Toxicol. Sci. 38 (2013), 741–752.
    • (2013) J. Toxicol. Sci. , vol.38 , pp. 741-752
    • Fang, J.L.1    Beland, F.A.2
  • 35
    • 84900988267 scopus 로고    scopus 로고
    • Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    • Franceschi, C., Campisi, J., Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J. Gerontol. A. Biol. Sci. Med. Sci. 69:Suppl. 1 (2014), S4–9.
    • (2014) J. Gerontol. A. Biol. Sci. Med. Sci. , vol.69 , pp. S4-9
    • Franceschi, C.1    Campisi, J.2
  • 36
    • 0032506207 scopus 로고    scopus 로고
    • HIV-1 gag proteins: diverse functions in the virus life cycle
    • Freed, E.O., HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 251 (1998), 1–15.
    • (1998) Virology , vol.251 , pp. 1-15
    • Freed, E.O.1
  • 37
    • 84861673276 scopus 로고    scopus 로고
    • Lamin B1 loss is a senescence-associated biomarker
    • Freund, A., Laberge, R.M., Demaria, M., Campisi, J., Lamin B1 loss is a senescence-associated biomarker. Mol. Biol. Cell 23 (2012), 2066–2075.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 2066-2075
    • Freund, A.1    Laberge, R.M.2    Demaria, M.3    Campisi, J.4
  • 39
    • 34547452631 scopus 로고    scopus 로고
    • Epidemiology of human immunodeficiency virus in the United States
    • table of contents
    • Hariri, S., McKenna, M.T., Epidemiology of human immunodeficiency virus in the United States. Clin. Microbiol. Rev. 20 (2007), 478–488 table of contents.
    • (2007) Clin. Microbiol. Rev. , vol.20 , pp. 478-488
    • Hariri, S.1    McKenna, M.T.2
  • 40
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley, C.B., Futcher, A.B., Greider, C.W., Telomeres shorten during ageing of human fibroblasts. Nature 345 (1990), 458–460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 41
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick, L., Moorhead, P.S., The serial cultivation of human diploid cell strains. Exp. Cell Res. 25 (1961), 585–621.
    • (1961) Exp. Cell Res. , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 42
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick, L., The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37 (1965), 614–636.
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 43
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
    • Herbig, U., Jobling, W.A., Chen, B.P., Chen, D.J., Sedivy, J.M., Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14 (2004), 501–513.
    • (2004) Mol. Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.M.5
  • 44
    • 84888133781 scopus 로고    scopus 로고
    • HIV protease inhibitors induce senescence and alter osteoblastic potential of human bone marrow mesenchymal stem cells: beneficial effect of pravastatin
    • Hernandez-Vallejo, S.J., Beaupere, C., Larghero, J., Capeau, J., Lagathu, C., HIV protease inhibitors induce senescence and alter osteoblastic potential of human bone marrow mesenchymal stem cells: beneficial effect of pravastatin. Aging cell 12 (2013), 955–965.
    • (2013) Aging cell , vol.12 , pp. 955-965
    • Hernandez-Vallejo, S.J.1    Beaupere, C.2    Larghero, J.3    Capeau, J.4    Lagathu, C.5
  • 47
    • 84867647498 scopus 로고    scopus 로고
    • Inflammation in aging: cause, effect, or both?
    • Jenny, N.S., Inflammation in aging: cause, effect, or both?. Discov. Med. 13 (2012), 451–460.
    • (2012) Discov. Med. , vol.13 , pp. 451-460
    • Jenny, N.S.1
  • 49
    • 68049147010 scopus 로고    scopus 로고
    • Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway
    • Junhui, Z., Xiaojing, H., Binquan, Z., Xudong, X., Junzhu, C., Guosheng, F., Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway. Cytotherapy 11 (2009), 485–491.
    • (2009) Cytotherapy , vol.11 , pp. 485-491
    • Junhui, Z.1    Xiaojing, H.2    Binquan, Z.3    Xudong, X.4    Junzhu, C.5    Guosheng, F.6
  • 51
    • 84862558202 scopus 로고    scopus 로고
    • Vascular calcification and hypertension: cause and effect
    • Kalra, S.S., Shanahan, C.M., Vascular calcification and hypertension: cause and effect. Ann. Med. 44:Suppl 1 (2012), S85–92.
    • (2012) Ann. Med. , vol.44 , pp. S85-92
    • Kalra, S.S.1    Shanahan, C.M.2
  • 54
    • 79851493300 scopus 로고    scopus 로고
    • Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a)
    • Kosar, M., Bartkova, J., Hubackova, S., Hodny, Z., Lukas, J., Bartek, J., Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a). ABBV Cell Cycle 10 (2011), 457–468.
    • (2011) ABBV Cell Cycle , vol.10 , pp. 457-468
    • Kosar, M.1    Bartkova, J.2    Hubackova, S.3    Hodny, Z.4    Lukas, J.5    Bartek, J.6
  • 55
    • 84866180243 scopus 로고    scopus 로고
    • The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation
    • Kousik, S.M., Napier, T.C., Carvey, P.M., The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation. Front. Pharmacol., 3, 2012, 121.
    • (2012) Front. Pharmacol. , vol.3 , pp. 121
    • Kousik, S.M.1    Napier, T.C.2    Carvey, P.M.3
  • 57
    • 84860608697 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by senescent fibroblasts
    • Laberge, R.M., Awad, P., Campisi, J., Desprez, P.Y., Epithelial-mesenchymal transition induced by senescent fibroblasts. Cancer Microenviron. 5 (2012), 39–44.
    • (2012) Cancer Microenviron. , vol.5 , pp. 39-44
    • Laberge, R.M.1    Awad, P.2    Campisi, J.3    Desprez, P.Y.4
  • 58
    • 82755197066 scopus 로고    scopus 로고
    • The Myc/macrophage tango: oncogene-induced senescence, Myc style
    • Lee, S., Schmitt, C.A., Reimann, M., The Myc/macrophage tango: oncogene-induced senescence, Myc style. Semin. Cancer Biol. 21 (2011), 377–384.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 377-384
    • Lee, S.1    Schmitt, C.A.2    Reimann, M.3
  • 60
    • 84859230231 scopus 로고    scopus 로고
    • Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder
    • Letendre, S., Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder. Top. Antiviral Med. 19 (2011), 137–142.
    • (2011) Top. Antiviral Med. , vol.19 , pp. 137-142
    • Letendre, S.1
  • 61
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • Libby, P., Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 83 (2006), 456S–460S.
    • (2006) Am. J. Clin. Nutr. , vol.83 , pp. 456S-460S
    • Libby, P.1
  • 63
    • 85003220318 scopus 로고    scopus 로고
    • Cigarette smoke extract induces senescence of murine skeletal muscle cells by oxidative stress-induced down-regulation of histone deacetylase 2
    • Liu, W., Su, W., Yang, X., Bai, J., Zhong, X., He, Z., Cigarette smoke extract induces senescence of murine skeletal muscle cells by oxidative stress-induced down-regulation of histone deacetylase 2. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 31(630–633), 2015, 638.
    • (2015) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi , vol.31 , Issue.630-633 , pp. 638
    • Liu, W.1    Su, W.2    Yang, X.3    Bai, J.4    Zhong, X.5    He, Z.6
  • 65
    • 84876983642 scopus 로고    scopus 로고
    • Immunosenescence and age-related viral diseases
    • Ma, Y., Fang, M., Immunosenescence and age-related viral diseases. Sci. China Life Sci. 56 (2013), 399–405.
    • (2013) Sci. China Life Sci. , vol.56 , pp. 399-405
    • Ma, Y.1    Fang, M.2
  • 67
    • 33144478270 scopus 로고    scopus 로고
    • Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-lamin A G608G antibody
    • McClintock, D., Gordon, L.B., Djabali, K., Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-lamin A G608G antibody. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 2154–2159.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2154-2159
    • McClintock, D.1    Gordon, L.B.2    Djabali, K.3
  • 71
    • 84962001853 scopus 로고    scopus 로고
    • Mitochondrial stress induces cellular senescence in an mTORC1-dependent manner
    • Nacarelli, T., Azar, A., Sell, C., Mitochondrial stress induces cellular senescence in an mTORC1-dependent manner. Free Radic. Biol. Med. 95 (2016), 133–154.
    • (2016) Free Radic. Biol. Med. , vol.95 , pp. 133-154
    • Nacarelli, T.1    Azar, A.2    Sell, C.3
  • 72
    • 84866183226 scopus 로고    scopus 로고
    • Ageing as a risk factor for disease
    • Niccoli, T., Partridge, L., Ageing as a risk factor for disease. Curr. Biol. 22 (2012), R741–752.
    • (2012) Curr. Biol. , vol.22 , pp. R741-752
    • Niccoli, T.1    Partridge, L.2
  • 73
    • 11144314750 scopus 로고    scopus 로고
    • Complications associated with NRTI therapy: update on clinical features and possible pathogenic mechanisms
    • Nolan, D., Mallal, S., Complications associated with NRTI therapy: update on clinical features and possible pathogenic mechanisms. Antivir. Ther. 9 (2004), 849–863.
    • (2004) Antivir. Ther. , vol.9 , pp. 849-863
    • Nolan, D.1    Mallal, S.2
  • 74
    • 0344513984 scopus 로고    scopus 로고
    • Metabolic complications associated with HIV protease inhibitor therapy
    • Nolan, D., Metabolic complications associated with HIV protease inhibitor therapy. Drugs 63 (2003), 2555–2574.
    • (2003) Drugs , vol.63 , pp. 2555-2574
    • Nolan, D.1
  • 78
    • 84874533741 scopus 로고    scopus 로고
    • Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study
    • Pathai, S., Lawn, S.D., Shiels, P.G., Weiss, H.A., Cook, C., Wood, R., Gilbert, C.E., Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study. PLoS One, 8, 2013, e57422.
    • (2013) PLoS One , vol.8 , pp. e57422
    • Pathai, S.1    Lawn, S.D.2    Shiels, P.G.3    Weiss, H.A.4    Cook, C.5    Wood, R.6    Gilbert, C.E.7
  • 80
    • 70350150677 scopus 로고    scopus 로고
    • Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism
    • Pricola, K.L., Kuhn, N.Z., Haleem-Smith, H., Song, Y., Tuan, R.S., Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism. J. Cell. Biochem. 108 (2009), 577–588.
    • (2009) J. Cell. Biochem. , vol.108 , pp. 577-588
    • Pricola, K.L.1    Kuhn, N.Z.2    Haleem-Smith, H.3    Song, Y.4    Tuan, R.S.5
  • 81
    • 35548955041 scopus 로고    scopus 로고
    • Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers
    • Reece, A.S., Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers. Immun. Ageing, 4, 2007, 6.
    • (2007) Immun. Ageing , vol.4 , pp. 6
    • Reece, A.S.1
  • 84
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi, D.J., Bryder, D., Seita, J., Nussenzweig, A., Hoeijmakers, J., Weissman, I.L., Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447 (2007), 725–729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 85
    • 66149128066 scopus 로고    scopus 로고
    • The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells
    • Rossi, A., Russo, G., Puca, A., La Montagna, R., Caputo, M., Mattioli, E., Lopez, M., Giordano, A., Pentimalli, F., The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells. Int. J. Cancer 125 (2009), 235–243.
    • (2009) Int. J. Cancer , vol.125 , pp. 235-243
    • Rossi, A.1    Russo, G.2    Puca, A.3    La Montagna, R.4    Caputo, M.5    Mattioli, E.6    Lopez, M.7    Giordano, A.8    Pentimalli, F.9
  • 87
    • 58149133507 scopus 로고    scopus 로고
    • Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition
    • Sarafianos, S.G., Marchand, B., Das, K., Himmel, D.M., Parniak, M.A., Hughes, S.H., Arnold, E., Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. J. Mol. Biol. 385 (2009), 693–713.
    • (2009) J. Mol. Biol. , vol.385 , pp. 693-713
    • Sarafianos, S.G.1    Marchand, B.2    Das, K.3    Himmel, D.M.4    Parniak, M.A.5    Hughes, S.H.6    Arnold, E.7
  • 88
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D., Lowe, S.W., Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88 (1997), 593–602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 89
    • 33746555576 scopus 로고    scopus 로고
    • HIV/AIDS epidemiology, pathogenesis, prevention, and treatment
    • Simon, V., Ho, D.D., Abdool Karim, Q., HIV/AIDS epidemiology, pathogenesis, prevention, and treatment. Lancet 368 (2006), 489–504.
    • (2006) Lancet , vol.368 , pp. 489-504
    • Simon, V.1    Ho, D.D.2    Abdool Karim, Q.3
  • 90
    • 43049148447 scopus 로고    scopus 로고
    • Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors
    • Sluis-Cremer, N., Tachedjian, G., Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors. Virus Res. 134 (2008), 147–156.
    • (2008) Virus Res. , vol.134 , pp. 147-156
    • Sluis-Cremer, N.1    Tachedjian, G.2
  • 93
    • 84965157556 scopus 로고    scopus 로고
    • Clinical challenges in HIV/AIDS: Hints for advancing prevention and patient management strategies
    • Sued, O., Figueroa, M.I., Cahn, P., Clinical challenges in HIV/AIDS: Hints for advancing prevention and patient management strategies. Adv. Drug Deliv. Rev. 103 (2016), 5–19.
    • (2016) Adv. Drug Deliv. Rev. , vol.103 , pp. 5-19
    • Sued, O.1    Figueroa, M.I.2    Cahn, P.3
  • 94
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • Takai, H., Smogorzewska, A., de Lange, T., DNA damage foci at dysfunctional telomeres. Curr. Biol. 13 (2003), 1549–1556.
    • (2003) Curr. Biol. , vol.13 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    de Lange, T.3
  • 95
    • 84873929448 scopus 로고    scopus 로고
    • Latest trends in drugs of abuse − HIV infection and neuroAIDS
    • Tiwari, S., Nair, M.P., Saxena, S.K., Latest trends in drugs of abuse − HIV infection and neuroAIDS. Fut. Virol. 8 (2013), 121–127.
    • (2013) Fut. Virol. , vol.8 , pp. 121-127
    • Tiwari, S.1    Nair, M.P.2    Saxena, S.K.3
  • 96
    • 9744272376 scopus 로고    scopus 로고
    • Cigarette smoke induces senescence in alveolar epithelial cells
    • Tsuji, T., Aoshiba, K., Nagai, A., Cigarette smoke induces senescence in alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 31 (2004), 643–649.
    • (2004) Am. J. Respir. Cell Mol. Biol. , vol.31 , pp. 643-649
    • Tsuji, T.1    Aoshiba, K.2    Nagai, A.3
  • 97
    • 84859483420 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin
    • Velarde, M.C., Flynn, J.M., Day, N.U., Melov, S., Campisi, J., Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY) 4 (2012), 3–12.
    • (2012) Aging (Albany NY) , vol.4 , pp. 3-12
    • Velarde, M.C.1    Flynn, J.M.2    Day, N.U.3    Melov, S.4    Campisi, J.5
  • 98
    • 84896069552 scopus 로고    scopus 로고
    • 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms
    • Wan, C., Liu, J., Nie, X., Zhao, J., Zhou, S., Duan, Z., Tang, C., Liang, L., Xu, G., 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms. PLoS One, 9, 2014, e89811.
    • (2014) PLoS One , vol.9 , pp. e89811
    • Wan, C.1    Liu, J.2    Nie, X.3    Zhao, J.4    Zhou, S.5    Duan, Z.6    Tang, C.7    Liang, L.8    Xu, G.9
  • 99
    • 84901020809 scopus 로고    scopus 로고
    • M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease
    • Wan, J., Benkdane, M., Alons, E., Lotersztajn, S., Pavoine, C., M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease. Am. J. Pathol. 184 (2014), 1763–1772.
    • (2014) Am. J. Pathol. , vol.184 , pp. 1763-1772
    • Wan, J.1    Benkdane, M.2    Alons, E.3    Lotersztajn, S.4    Pavoine, C.5
  • 102
    • 84907209549 scopus 로고    scopus 로고
    • Inflammatory response in parkinson's disease (review)
    • Yan, J., Fu, Q., Cheng, L., Zhai, M., Wu, W., Huang, L., Du, G., Inflammatory response in parkinson's disease (review). Mol. Med. Rep. 10 (2014), 2223–2233.
    • (2014) Mol. Med. Rep. , vol.10 , pp. 2223-2233
    • Yan, J.1    Fu, Q.2    Cheng, L.3    Zhai, M.4    Wu, W.5    Huang, L.6    Du, G.7
  • 103
    • 78149455160 scopus 로고    scopus 로고
    • Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120
    • Yang, Y., Yao, H., Lu, Y., Wang, C., Buch, S., Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120. PLoS One, 5, 2010, e13427.
    • (2010) PLoS One , vol.5 , pp. e13427
    • Yang, Y.1    Yao, H.2    Lu, Y.3    Wang, C.4    Buch, S.5
  • 104
    • 30844434561 scopus 로고    scopus 로고
    • Prelamin A, Zmpste24, misshapen cell nuclei, and progeria–new evidence suggesting that protein farnesylation could be important for disease pathogenesis
    • Young, S.G., Fong, L.G., Michaelis, S., Prelamin A, Zmpste24, misshapen cell nuclei, and progeria–new evidence suggesting that protein farnesylation could be important for disease pathogenesis. J. Lipid Res. 46 (2005), 2531–2558.
    • (2005) J. Lipid Res. , vol.46 , pp. 2531-2558
    • Young, S.G.1    Fong, L.G.2    Michaelis, S.3
  • 105
    • 10744223612 scopus 로고    scopus 로고
    • Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence
    • Zanni, F., Vescovini, R., Biasini, C., Fagnoni, F., Zanlari, L., Telera, A., Di Pede, P., Passeri, G., Pedrazzoni, M., Passeri, M., Franceschi, C., Sansoni, P., Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence. Exp. Gerontol. 38 (2003), 981–987.
    • (2003) Exp. Gerontol. , vol.38 , pp. 981-987
    • Zanni, F.1    Vescovini, R.2    Biasini, C.3    Fagnoni, F.4    Zanlari, L.5    Telera, A.6    Di Pede, P.7    Passeri, G.8    Pedrazzoni, M.9    Passeri, M.10    Franceschi, C.11    Sansoni, P.12
  • 106
    • 84955069529 scopus 로고    scopus 로고
    • CSGene: a literature-based database for cell senescence genes and its application to identify critical cell aging pathways and associated diseases
    • Zhao, M., Chen, L., Qu, H., CSGene: a literature-based database for cell senescence genes and its application to identify critical cell aging pathways and associated diseases. Cell. Death. Dis., 7, 2016, e2053.
    • (2016) Cell. Death. Dis. , vol.7 , pp. e2053
    • Zhao, M.1    Chen, L.2    Qu, H.3
  • 107
    • 84901288438 scopus 로고    scopus 로고
    • The role of senescent cells in ageing
    • van Deursen, J.M., The role of senescent cells in ageing. Nature 509 (2014), 439–446.
    • (2014) Nature , vol.509 , pp. 439-446
    • van Deursen, J.M.1


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