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Volumn 2, Issue 7, 2012, Pages

HIV DNA integration

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; INTEGRASE; LENS EPITHELIUM DERIVED GROWTH FACTOR; PROTEIN P75; SMALL INTERFERING RNA; VIRUS DNA; VIRUS NUCLEOPROTEIN; XRCC4 PROTEIN; LENS EPITHELIUM-DERIVED GROWTH FACTOR; SIGNAL PEPTIDE;

EID: 84867398216     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a006890     Document Type: Article
Times cited : (236)

References (133)
  • 1
    • 84865375176 scopus 로고    scopus 로고
    • HIV-1 antiretroviral drug therapy
    • doi: 10. 1101/cshperspect. a007161
    • Arts EJ, Hazuda DJ. 2011. HIV-1 antiretroviral drug therapy. Cold Spring Harb Perspect Med doi: 10. 1101/cshperspect. a007161.
    • (2011) Cold Spring Harb Perspect Med
    • Arts, E.J.1    Hazuda, D.J.2
  • 3
    • 0014964654 scopus 로고
    • RNA-dependent DNA polymerase in virions of RNA tumor viruses
    • Baltimore D. 1970. RNA-dependent DNA polymerase in virions of RNA tumor viruses. Nature 226: 1209-1211.
    • (1970) Nature , vol.226 , pp. 1209-1211
    • Baltimore, D.1
  • 4
    • 33745363486 scopus 로고    scopus 로고
    • HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry
    • Barr SD, Ciuffi A, Leipzig J, Shinn P, Ecker JR, Bushman FD. 2006. HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry. Mol Ther 14: 218-225.
    • (2006) Mol Ther , vol.14 , pp. 218-225
    • Barr, S.D.1    Ciuffi, A.2    Leipzig, J.3    Shinn, P.4    Ecker, J.R.5    Bushman, F.D.6
  • 5
    • 33751418954 scopus 로고    scopus 로고
    • Selection of target sites for mobile DNA integration in the human genome
    • doi: 10. 1371/journal. pcbi. 0020157
    • Berry C, Hannenhalli S, Leipzig J, Bushman FD. 2006. Selection of target sites for mobile DNA integration in the human genome. PLoS Comput Biol 2: e157. doi: 10. 1371/journal. pcbi. 0020157.
    • (2006) PLoS Comput Biol , vol.2
    • Berry, C.1    Hannenhalli, S.2    Leipzig, J.3    Bushman, F.D.4
  • 6
    • 0028874669 scopus 로고
    • In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends
    • Bor YC, Bushman F, Orgel L. 1995. In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. Proc Natl Acad Sci 92: 10334-10338.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 10334-10338
    • Bor, Y.C.1    Bushman, F.2    Orgel, L.3
  • 7
    • 0024654338 scopus 로고
    • A nucleoprotein complex mediates the integration of retroviral DNA
    • Bowerman B, Brown PO, Bishop JM, Varmus HE. 1989. A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev 3: 469-478.
    • (1989) Genes Dev , vol.3 , pp. 469-478
    • Bowerman, B.1    Brown, P.O.2    Bishop, J.M.3    Varmus, H.E.4
  • 11
    • 0023647997 scopus 로고
    • Correct integration of retroviral DNA in vitro
    • Brown PO, Bowerman B, Varmus HE, Bishop JM. 1987. Correct integration of retroviral DNA in vitro. Cell 49: 347-356.
    • (1987) Cell , vol.49 , pp. 347-356
    • Brown, P.O.1    Bowerman, B.2    Varmus, H.E.3    Bishop, J.M.4
  • 12
    • 0040896601 scopus 로고
    • Retroviral integration: Structure of the initial covalent complex and its precursor, and a role for the viral IN protein
    • Brown PO, Bowerman B, Varmus HE, Bishop JM. 1989. Retroviral integration: Structure of the initial covalent complex and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci 86: 2525-2529.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 2525-2529
    • Brown, P.O.1    Bowerman, B.2    Varmus, H.E.3    Bishop, J.M.4
  • 14
    • 0029815034 scopus 로고    scopus 로고
    • Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease
    • Bukovsky A, Gottlinger H. 1996. Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease. J Virol 70: 6820-6825.
    • (1996) J Virol , vol.70 , pp. 6820-6825
    • Bukovsky, A.1    Gottlinger, H.2
  • 15
    • 0027199982 scopus 로고
    • Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection
    • Bukrinsky MI, Sharova N, McDonald TL, Pushkarskaya T, Tarpley GW, Stevenson M. 1993. Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection. Proc Natl Acad Sci 90: 6125-6129.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 6125-6129
    • Bukrinsky, M.I.1    Sharova, N.2    McDonald, T.L.3    Pushkarskaya, T.4    Tarpley, G.W.5    Stevenson, M.6
  • 17
    • 0026568640 scopus 로고
    • Integration of human immunodeficiency virus DNA: Adduct interference analysis of required DNA sites
    • Bushman FD, Craigie R. 1992. Integration of human immunodeficiency virus DNA: Adduct interference analysis of required DNA sites. Proc Natl Acad Sci 89: 3458-3462.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 3458-3462
    • Bushman, F.D.1    Craigie, R.2
  • 18
    • 0025133394 scopus 로고
    • Retroviral DNA integration directed by HIV integration protein in vitro
    • Bushman FD, Fujiwara T, Craigie R. 1990. Retroviral DNA integration directed by HIV integration protein in vitro. Science 249: 1555-1558.
    • (1990) Science , vol.249 , pp. 1555-1558
    • Bushman, F.D.1    Fujiwara, T.2    Craigie, R.3
  • 19
    • 0027456715 scopus 로고
    • Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
    • Bushman FD, Engelman A, Palmer I, Wingfield P, Craigie R. 1993. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc Natl Acad Sci 90: 3428-3432.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 3428-3432
    • Bushman, F.D.1    Engelman, A.2    Palmer, I.3    Wingfield, P.4    Craigie, R.5
  • 24
    • 28444445583 scopus 로고    scopus 로고
    • Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator 75
    • Cherepanov P, Ambrosio AL, Rahman S, Ellenberger T, Engelman A. 2005. Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator 75. Proc Natl Acad Sci 102: 17308-17313.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 17308-17313
    • Cherepanov, P.1    Ambrosio, A.L.2    Rahman, S.3    Ellenberger, T.4    Engelman, A.5
  • 25
    • 2942553781 scopus 로고    scopus 로고
    • Structure and function of HIV-1 integrase
    • Chiu TK, Davies DR. 2004. Structure and function of HIV-1 integrase. Curr Top Med Chem 4: 965-977.
    • (2004) Curr Top Med Chem , vol.4 , pp. 965-977
    • Chiu, T.K.1    Davies, D.R.2
  • 27
    • 33745745419 scopus 로고    scopus 로고
    • Retroviral DNA integration: HIV and the role of LEDGF/p75
    • Ciuffi A, Bushman FD. 2006. Retroviral DNA integration: HIV and the role of LEDGF/p75. Trends Genet 22: 388-395.
    • (2006) Trends Genet , vol.22 , pp. 388-395
    • Ciuffi, A.1    Bushman, F.D.2
  • 29
    • 30344434648 scopus 로고    scopus 로고
    • Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts
    • Ciuffi A, Mitchell RS, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman FD. 2006. Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts. Mol Ther 13: 366-373.
    • (2006) Mol Ther , vol.13 , pp. 366-373
    • Ciuffi, A.1    Mitchell, R.S.2    Hoffmann, C.3    Leipzig, J.4    Shinn, P.5    Ecker, J.R.6    Bushman, F.D.7
  • 30
  • 32
    • 0025031786 scopus 로고
    • The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro
    • Craigie R, Fujiwara T, Bushman F. 1990. The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro. Cell 62: 829-837.
    • (1990) Cell , vol.62 , pp. 829-837
    • Craigie, R.1    Fujiwara, T.2    Bushman, F.3
  • 33
    • 0033597450 scopus 로고    scopus 로고
    • A role for DNA-PK in retroviral DNA integration
    • Daniel R, Katz RA, Skalka AM. 1999. A role for DNA-PK in retroviral DNA integration. Science 284: 644-647.
    • (1999) Science , vol.284 , pp. 644-647
    • Daniel, R.1    Katz, R.A.2    Skalka, A.M.3
  • 35
    • 0034616993 scopus 로고    scopus 로고
    • Three-dimensional structure of the Tn5 synaptic complex transposition intermediate
    • Davies DR, Goryshin IY, Reznikoff WS, Rayment I. 2000. Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science 289: 77-85.
    • (2000) Science , vol.289 , pp. 77-85
    • Davies, D.R.1    Goryshin, I.Y.2    Reznikoff, W.S.3    Rayment, I.4
  • 38
    • 0342452981 scopus 로고
    • A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration
    • Donehower LA, Varmus HE. 1984. A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration. Proc Natl Acad Sci 81: 6461-6465.
    • (1984) Proc Natl Acad Sci , vol.81 , pp. 6461-6465
    • Donehower, L.A.1    Varmus, H.E.2
  • 39
    • 0030864070 scopus 로고    scopus 로고
    • A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site
    • Du Z, Ilyinskii PO, Lally K, Desrosiers RC, Engelman A. 1997. A mutation in integrase can compensate for mutations in the simian immunodeficiency virus att site. J Virol 71: 8124-8132.
    • (1997) J Virol , vol.71 , pp. 8124-8132
    • Du, Z.1    Ilyinskii, P.O.2    Lally, K.3    Desrosiers, R.C.4    Engelman, A.5
  • 40
    • 0028584269 scopus 로고
    • Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases
    • Dyda F, Hickman AB, Jenkins TM, Engelman A, Craigie R, Davies DR. 1994. Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases. Science 266: 1981-1986.
    • (1994) Science , vol.266 , pp. 1981-1986
    • Dyda, F.1    Hickman, A.B.2    Jenkins, T.M.3    Engelman, A.4    Craigie, R.5    Davies, D.R.6
  • 43
    • 0025337327 scopus 로고
    • Human immunodeficiency virus integration in a cell-free system
    • Ellison VH, Abrams H, Roe T, Lifson J, Brown PO. 1990. Human immunodeficiency virus integration in a cell-free system. J Virol 64: 2711-2715.
    • (1990) J Virol , vol.64 , pp. 2711-2715
    • Ellison, V.H.1    Abrams, H.2    Roe, T.3    Lifson, J.4    Brown, P.O.5
  • 45
    • 0026649557 scopus 로고
    • Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
    • Engelman A, Craigie R. 1992. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J Virol 66: 6361-6369.
    • (1992) J Virol , vol.66 , pp. 6361-6369
    • Engelman, A.1    Craigie, R.2
  • 46
    • 0026330796 scopus 로고
    • HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
    • Engelman A, Mizuuchi K, Craigie R. 1991. HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer. Cell 67: 1211-1221.
    • (1991) Cell , vol.67 , pp. 1211-1221
    • Engelman, A.1    Mizuuchi, K.2    Craigie, R.3
  • 48
    • 0025313138 scopus 로고
    • Integration of human immunodeficiency virus type 1 DNA in vitro
    • Farnet CM, Haseltine WA. 1990. Integration of human immunodeficiency virus type 1 DNA in vitro. Proc Natl Acad Sci 87: 4164-4168.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 4164-4168
    • Farnet, C.M.1    Haseltine, W.A.2
  • 49
    • 0025719637 scopus 로고
    • Circularization of human immunodeficiency virus type 1 DNA in vitro
    • Farnet CM, Haseltine WA. 1991a. Circularization of human immunodeficiency virus type 1 DNA in vitro. J Virol 65: 6942-6952.
    • (1991) J Virol , vol.65 , pp. 6942-6952
    • Farnet, C.M.1    Haseltine, W.A.2
  • 50
    • 0025968854 scopus 로고
    • Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex
    • Farnet CM, Haseltine WA. 1991b. Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J Virol 65: 1910-1915.
    • (1991) J Virol , vol.65 , pp. 1910-1915
    • Farnet, C.M.1    Haseltine, W.A.2
  • 51
    • 33751007834 scopus 로고    scopus 로고
    • HIV infection of non-dividing cells: A divisive problem
    • Fassati A. 2006. HIV infection of non-dividing cells: A divisive problem. Retrovirology 3: 74.
    • (2006) Retrovirology , vol.3 , pp. 74
    • Fassati, A.1
  • 53
    • 3043000364 scopus 로고
    • Integration of mini-retroviral DNA: A cell-free reaction for biochemical analysis of retroviral integration
    • Fujiwara T, Craigie R. 1989. Integration of mini-retroviral DNA: A cell-free reaction for biochemical analysis of retroviral integration. Proc Natl Acad Sci 86: 3065-3069.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 3065-3069
    • Fujiwara, T.1    Craigie, R.2
  • 54
    • 0023687763 scopus 로고
    • Retroviral DNA integration: Structure of an integration intermediate
    • Fujiwara T, Mizuuchi K. 1988. Retroviral DNA integration: Structure of an integration intermediate. Cell 54: 497-504.
    • (1988) Cell , vol.54 , pp. 497-504
    • Fujiwara, T.1    Mizuuchi, K.2
  • 55
    • 0032538795 scopus 로고    scopus 로고
    • Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
    • Ge H, Si Y, Roeder RG. 1998. Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation. EMBO J 17: 6723-6729.
    • (1998) EMBO J , vol.17 , pp. 6723-6729
    • Ge, H.1    Si, Y.2    Roeder, R.G.3
  • 57
    • 0018090196 scopus 로고
    • A 32, 000-dalton nucleic acid-binding protein from avian retrovirus cores possesses DNA endonuclease activity
    • Grandgenett DP, Vora AC, Schiff RD. 1978. A 32, 000-dalton nucleic acid-binding protein from avian retrovirus cores possesses DNA endonuclease activity. Virology 89: 119-132.
    • (1978) Virology , vol.89 , pp. 119-132
    • Grandgenett, D.P.1    Vora, A.C.2    Schiff, R.D.3
  • 58
    • 0036062256 scopus 로고    scopus 로고
    • Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy
    • Greene WC, Peterlin BM. 2002. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med 8: 673-680.
    • (2002) Nat Med , vol.8 , pp. 673-680
    • Greene, W.C.1    Peterlin, B.M.2
  • 60
    • 59249089461 scopus 로고    scopus 로고
    • A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
    • doi: 10. 1371/journal. ppat. 1000259
    • Hare S, Shun MC, Gupta SS, Valkov E, Engelman A, Cherepanov P. 2009. A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75. Plos Pathogens5. doi: 10. 1371/journal. ppat. 1000259.
    • (2009) Plos Pathogens , vol.5
    • Hare, S.1    Shun, M.C.2    Gupta, S.S.3    Valkov, E.4    Engelman, A.5    Cherepanov, P.6
  • 61
    • 77949365510 scopus 로고    scopus 로고
    • Retroviral intasome assembly and inhibition of DNA strand transfer
    • Hare S, Gupta SS, Valkov E, Engelman A, Cherepanov P. 2010. Retroviral intasome assembly and inhibition of DNA strand transfer. Nature 464: 232-236.
    • (2010) Nature , vol.464 , pp. 232-236
    • Hare, S.1    Gupta, S.S.2    Valkov, E.3    Engelman, A.4    Cherepanov, P.5
  • 62
    • 0033052713 scopus 로고    scopus 로고
    • HMG protein family members stimulate human immunodeficiency virus type 1 avian sarcoma virus concerted DNA integration in vitro
    • Hindmarsh P, Ridky T, Reeves R, Andrake M, Skalka AM, Leis J. 1999. HMG protein family members stimulate human immunodeficiency virus type 1 avian sarcoma virus concerted DNA integration in vitro. J Virol 73: 2994-3003.
    • (1999) J Virol , vol.73 , pp. 2994-3003
    • Hindmarsh, P.1    Ridky, T.2    Reeves, R.3    Andrake, M.4    Skalka, A.M.5    Leis, J.6
  • 63
    • 17844381584 scopus 로고    scopus 로고
    • Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites
    • Holman AG, Coffin JM. 2005. Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites. Proc Natl Acad Sci 102: 6103-6107.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 6103-6107
    • Holman, A.G.1    Coffin, J.M.2
  • 65
    • 84872675799 scopus 로고    scopus 로고
    • HIV reverse transcription: Virally encoded enzyme
    • doi: 10. 1101/cshperspect. a006882
    • Hu W-S, Hughes SH. 2011. HIV reverse transcription: Virally encoded enzyme. Cold Spring Harb Perspect Med doi: 10. 1101/cshperspect. a006882.
    • (2011) Cold Spring Harb Perspect Med
    • Hu, W.-S.1    Hughes, S.H.2
  • 66
    • 65549105028 scopus 로고    scopus 로고
    • Piecing together the structure of retroviral integrase, an important target in AIDS therapy
    • Jaskolski M, Alexandratos JN, Bujacz G, Wlodawer A. 2009. Piecing together the structure of retroviral integrase, an important target in AIDS therapy. FEBS J276: 2926-2946.
    • (2009) FEBS J , vol.276 , pp. 2926-2946
    • Jaskolski, M.1    Alexandratos, J.N.2    Bujacz, G.3    Wlodawer, A.4
  • 68
    • 0029017919 scopus 로고
    • Catalytic domain of human immunodeficiency virus type 1 integrase: Identification of a soluble mutant by systematic replacement of hydrophobic residues
    • Jenkins TM, Hickman AB, Dyda F, Ghirlando R, Davies DR, Craigie R. 1995. Catalytic domain of human immunodeficiency virus type 1 integrase: Identification of a soluble mutant by systematic replacement of hydrophobic residues. Proc Natl Acad Sci 92: 6057-6061.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 6057-6061
    • Jenkins, T.M.1    Hickman, A.B.2    Dyda, F.3    Ghirlando, R.4    Davies, D.R.5    Craigie, R.6
  • 69
    • 0035794637 scopus 로고    scopus 로고
    • The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
    • Jordan A, Defechereux P, Verdin E. 2001. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J 20: 1726-1738.
    • (2001) EMBO J , vol.20 , pp. 1726-1738
    • Jordan, A.1    Defechereux, P.2    Verdin, E.3
  • 70
    • 0019161455 scopus 로고
    • Nucleotide sequence analysis of the long terminal repeat (LTR) of avian retroviruses: Structural similarities with transposable elements
    • Ju G, Skalka AM. 1980. Nucleotide sequence analysis of the long terminal repeat (LTR) of avian retroviruses: Structural similarities with transposable elements. Cell 22: 379-386.
    • (1980) Cell , vol.22 , pp. 379-386
    • Ju, G.1    Skalka, A.M.2
  • 71
    • 0025011051 scopus 로고
    • The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro
    • Katz RA, Merkel G, Kulkosky J, Leis J, Skalka AM. 1990. The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro. Cell 63: 87-95.
    • (1990) Cell , vol.63 , pp. 87-95
    • Katz, R.A.1    Merkel, G.2    Kulkosky, J.3    Leis, J.4    Skalka, A.M.5
  • 72
    • 0032508613 scopus 로고    scopus 로고
    • A preferred target DNA structure for retroviral integrase in vitro
    • Katz RA, Gravuer K, Skalka AM. 1998. A preferred target DNA structure for retroviral integrase in vitro. J Biol Chem 273: 24190-24195.
    • (1998) J Biol Chem , vol.273 , pp. 24190-24195
    • Katz, R.A.1    Gravuer, K.2    Skalka, A.M.3
  • 73
    • 0024431589 scopus 로고
    • The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration
    • Katzman M, Katz RA, Skalka AM, Leis J. 1989. The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration. J Virol 63: 5319-5327.
    • (1989) J Virol , vol.63 , pp. 5319-5327
    • Katzman, M.1    Katz, R.A.2    Skalka, A.M.3    Leis, J.4
  • 77
    • 0026719238 scopus 로고
    • Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
    • Kulkosky J, Jones KS, Katz RA, Mack JPG, Skalka AM. 1992. Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol Cell Biol 12: 2331-2338.
    • (1992) Mol Cell Biol , vol.12 , pp. 2331-2338
    • Kulkosky, J.1    Jones, K.S.2    Katz, R.A.3    McK, J.P.G.4    Skalka, A.M.5
  • 78
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E. 2001. Initial sequencing and analysis of the human genome. Nature 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.1
  • 79
    • 0027470432 scopus 로고
    • Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
    • Leavitt AD, Shiue L, Varmus HE. 1993. Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. J Biol Chem 268: 2113-2119.
    • (1993) J Biol Chem , vol.268 , pp. 2113-2119
    • Leavitt, A.D.1    Shiue, L.2    Varmus, H.E.3
  • 80
    • 0032539631 scopus 로고    scopus 로고
    • Protection of retroviral DNA from autointegration: Involvement of a cellular factor
    • Lee MS, Craigie R. 1998. Protection of retroviral DNA from autointegration: Involvement of a cellular factor. Proc Natl Acad Sci 95: 1528-1533.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 1528-1533
    • Lee, M.S.1    Craigie, R.2
  • 84
    • 23844491860 scopus 로고    scopus 로고
    • Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration
    • Li M, Craigie R. 2005. Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration. J Biol Chem 280: 29334-29339.
    • (2005) J Biol Chem , vol.280 , pp. 29334-29339
    • Li, M.1    Craigie, R.2
  • 86
    • 33645285267 scopus 로고    scopus 로고
    • Retroviral DNA integration: Reaction pathway and critical intermediates
    • Li M, Mizuuchi M, Burke TR Jr., Craigie R. 2006. Retroviral DNA integration: Reaction pathway and critical intermediates. EMBO J 25: 1295-1304.
    • (2006) EMBO J , vol.25 , pp. 1295-1304
    • Li, M.1    Mizuuchi, M.2    Burke Jr., T.R.3    Craigie, R.4
  • 88
    • 33745617039 scopus 로고    scopus 로고
    • Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75
    • Llano M, Vanegas M, Hutchins N, Thompson D, Delgado S, Poeschla EM. 2006b. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. J Mol Biol 360: 760-773.
    • (2006) J Mol Biol , vol.360 , pp. 760-773
    • Llano, M.1    Vanegas, M.2    Hutchins, N.3    Thompson, D.4    Delgado, S.5    Poeschla, E.M.6
  • 91
    • 78149434355 scopus 로고    scopus 로고
    • The mechanism of retroviral integration from X-ray structures of its key intermediates
    • Maertens GN, Hare S, Cherepanov P. 2010. The mechanism of retroviral integration from X-ray structures of its key intermediates. Nature 468: 326-329.
    • (2010) Nature , vol.468 , pp. 326-329
    • Maertens, G.N.1    Hare, S.2    Cherepanov, P.3
  • 94
    • 0026799383 scopus 로고
    • Polynucleotidyl transfer reactions in transpositional DNA recombination
    • Mizuuchi K. 1992. Polynucleotidyl transfer reactions in transpositional DNA recombination. J Biol Chem 287: 21273-21276.
    • (1992) J Biol Chem , vol.287 , pp. 21273-21276
    • Mizuuchi, K.1
  • 95
    • 0025899314 scopus 로고
    • Inversion of the phosphate chirality at the target site of Mu-DNA strand transfer-Evidence for a one-step transesterification mechanism
    • Mizuuchi K, Adzuma K. 1991. Inversion of the phosphate chirality at the target site of Mu-DNA strand transfer-Evidence for a one-step transesterification mechanism. Cell 66: 129-140.
    • (1991) Cell , vol.66 , pp. 129-140
    • Mizuuchi, K.1    Adzuma, K.2
  • 97
    • 0026652466 scopus 로고
    • A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo
    • Murphy JE, Goff SP. 1992. A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo. J Virol 66: 5092-5095.
    • (1992) J Virol , vol.66 , pp. 5092-5095
    • Murphy, J.E.1    Goff, S.P.2
  • 98
    • 0027313293 scopus 로고
    • Mutational analysis of the sequences at the termini of the Moloney murine leukemia virus DNA required for integration
    • Murphy JE, De Los Santos T, Goff SP. 1993. Mutational analysis of the sequences at the termini of the Moloney murine leukemia virus DNA required for integration. Virology 195: 432-440.
    • (1993) Virology , vol.195 , pp. 432-440
    • Murphy, J.E.1    De Los Santos, T.2    Goff, S.P.3
  • 100
    • 0021022185 scopus 로고
    • The terminal nucleotides of retrovirus DNA are required for integration but not virus production
    • Panganiban AT, Temin HM. 1983. The terminal nucleotides of retrovirus DNA are required for integration but not virus production. Nature 306: 155-160.
    • (1983) Nature , vol.306 , pp. 155-160
    • Panganiban, A.T.1    Temin, H.M.2
  • 101
    • 0342466800 scopus 로고
    • The retrovirus pol gene encodes a product required for DNA integration: Identification of a retrovirus int locus
    • Panganiban AT, Temin HM. 1984. The retrovirus pol gene encodes a product required for DNA integration: Identification of a retrovirus int locus. Proc Natl Acad Sci 81: 7885-7889.
    • (1984) Proc Natl Acad Sci , vol.81 , pp. 7885-7889
    • Panganiban, A.T.1    Temin, H.M.2
  • 102
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD. 1996. HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time. Science 271: 1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 103
    • 0028264042 scopus 로고
    • Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core
    • Pruss D, Bushman FD, Wolffe AP. 1994. Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core. Proc Natl Acad Sci 91: 5913-5917.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 5913-5917
    • Pruss, D.1    Bushman, F.D.2    Wolffe, A.P.3
  • 104
    • 0026696624 scopus 로고
    • Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
    • Pryciak PM, Varmus HE. 1992. Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell 69: 769-780.
    • (1992) Cell , vol.69 , pp. 769-780
    • Pryciak, P.M.1    Varmus, H.E.2
  • 105
    • 0026567862 scopus 로고
    • Retroviral integration into minichromosomes in vitro
    • Pryciak PM, Sil A, Varmus HE. 1992. Retroviral integration into minichromosomes in vitro. EMBO J 11: 291-303.
    • (1992) EMBO J , vol.11 , pp. 291-303
    • Pryciak, P.M.1    Sil, A.2    Varmus, H.E.3
  • 107
    • 70149109999 scopus 로고    scopus 로고
    • Molecular architecture of the Mos1 paired-end complex: The structural basis of DNA transposition in a eukaryote
    • Richardson JM, Colloms SD, Finnegan DJ, Walkinshaw MD. 2009. Molecular architecture of the Mos1 paired-end complex: The structural basis of DNA transposition in a eukaryote. Cell 138: 1096-1108.
    • (2009) Cell , vol.138 , pp. 1096-1108
    • Richardson, J.M.1    Colloms, S.D.2    Finnegan, D.J.3    Walkinshaw, M.D.4
  • 108
    • 0027158091 scopus 로고
    • Integration of murine leukemia virus DNA depends on mitosis
    • Roe T, Reynolds TC, Yu G, Brown PO. 1993. Integration of murine leukemia virus DNA depends on mitosis. EMBO J 12: 2099-2108.
    • (1993) EMBO J , vol.12 , pp. 2099-2108
    • Roe, T.1    Reynolds, T.C.2    Yu, G.3    Brown, P.O.4
  • 109
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F. 2002. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110: 521-529.
    • (2002) Cell , vol.110 , pp. 521-529
    • Schroder, A.R.1    Shinn, P.2    Chen, H.3    Berry, C.4    Ecker, J.R.5    Bushman, F.6
  • 110
    • 0021729809 scopus 로고
    • Construction and analysis of deletion mutations in the pol gene of Moloney murine leukemia virus: A new viral function required for productive infection
    • Schwartzberg P, Colecilli J, Goff SP. 1984. Construction and analysis of deletion mutations in the pol gene of Moloney murine leukemia virus: A new viral function required for productive infection. Cell 37: 1043-1052.
    • (1984) Cell , vol.37 , pp. 1043-1052
    • Schwartzberg, P.1    Colecilli, J.2    Goff, S.P.3
  • 111
    • 0018937587 scopus 로고
    • Sequence of retrovirus provirus resembles that of bacterial transposable elements
    • Shimotohno K, Mizutani S, Temin HM. 1980. Sequence of retrovirus provirus resembles that of bacterial transposable elements. Nature 285: 550-554.
    • (1980) Nature , vol.285 , pp. 550-554
    • Shimotohno, K.1    Mizutani, S.2    Temin, H.M.3
  • 112
    • 0019304428 scopus 로고
    • Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: Implications for retrovirus integration
    • Shoemaker CS, Goff S, Giboa E, Paskind M, Mitra SW, Baltimore D. 1980. Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: Implications for retrovirus integration. Proc Natl Acad Sci 77: 3932-3936.
    • (1980) Proc Natl Acad Sci , vol.77 , pp. 3932-3936
    • Shoemaker, C.S.1    Goff, S.2    Giboa, E.3    Paskind, M.4    Mitra, S.W.5    Baltimore, D.6
  • 114
    • 77949707011 scopus 로고    scopus 로고
    • Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein
    • Silvers RM, Smith JA, Schowalter M, Litwin S, Liang ZH, Geary K, Daniel R. 2010. Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein. Hum Gene Ther 21: 337-349.
    • (2010) Hum Gene Ther , vol.21 , pp. 337-349
    • Silvers, R.M.1    Smith, J.A.2    Schowalter, M.3    Litwin, S.4    Liang, Z.H.5    Geary, K.6    Daniel, R.7
  • 115
    • 0036118227 scopus 로고    scopus 로고
    • Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors
    • Sinha S, Pursley MH, Grandgenett DP. 2002. Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors. J Virol 76: 3105-3113.
    • (2002) J Virol , vol.76 , pp. 3105-3113
    • Sinha, S.1    Pursley, M.H.2    Grandgenett, D.P.3
  • 116
    • 20744447462 scopus 로고    scopus 로고
    • Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells
    • Sinha S, Grandgenett DP. 2005. Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells. J Virol 79: 8208-8216.
    • (2005) J Virol , vol.79 , pp. 8208-8216
    • Sinha, S.1    Grandgenett, D.P.2
  • 117
    • 0028277393 scopus 로고
    • Human immunodeficiency virus type 1 may preferentially integrate into chromatin occupied by L1Hs repetitive elements
    • Stevens SW, Griffith JD. 1994. Human immunodeficiency virus type 1 may preferentially integrate into chromatin occupied by L1Hs repetitive elements. Proc Natl Acad Sci 91: 5557-5561.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 5557-5561
    • Stevens, S.W.1    Griffith, J.D.2
  • 118
    • 33847139800 scopus 로고    scopus 로고
    • The road to chromatin-Nuclear entry of retroviruses
    • Suzuki Y, Craigie R. 2007. The road to chromatin-Nuclear entry of retroviruses. Nat Rev Microbiol 5: 187-196.
    • (2007) Nat Rev Microbiol , vol.5 , pp. 187-196
    • Suzuki, Y.1    Craigie, R.2
  • 119
    • 0017154790 scopus 로고
    • The DNA provirus hypothesis
    • Temin HM. 1976. The DNA provirus hypothesis. Science 192: 1075-1080.
    • (1976) Science , vol.192 , pp. 1075-1080
    • Temin, H.M.1
  • 120
    • 0014964695 scopus 로고
    • RNA-dependent DNA polymerase in virions of Rous sarcoma virus
    • Temin H, Mizutani S. 1970. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 226: 1211-1213.
    • (1970) Nature , vol.226 , pp. 1211-1213
    • Temin, H.1    Mizutani, S.2
  • 121
    • 8644231282 scopus 로고    scopus 로고
    • Human cell proteins and human immunodeficiency virus DNA integration
    • Turlure F, Devroe E, Silver PA, Engelman A. 2004. Human cell proteins and human immunodeficiency virus DNA integration. Front Biosci 9: 3187-3208.
    • (2004) Front Biosci , vol.9 , pp. 3187-3208
    • Turlure, F.1    Devroe, E.2    Silver, P.A.3    Engelman, A.4
  • 122
    • 33645528413 scopus 로고    scopus 로고
    • A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo
    • Turlure F, Maertens G, Rahman S, Cherepanov P, Engelman A. 2006. A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo. Nucleic Acids Res 34: 1653-1665.
    • (2006) Nucleic Acids Res , vol.34 , pp. 1653-1665
    • Turlure, F.1    Maertens, G.2    Rahman, S.3    Cherepanov, P.4    Engelman, A.5
  • 123
    • 0026668776 scopus 로고
    • Mutational analysis of the integrase protein of human immunodeficiency virus type 2
    • van Gent DC, Oude Groeneger AAM, Plasterk RHA. 1992. Mutational analysis of the integrase protein of human immunodeficiency virus type 2. Proc Natl Acad Sci 89: 9598-9602.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 9598-9602
    • van Gent, D.C.1    Oude Groeneger, A.A.M.2    Plasterk, R.H.A.3
  • 124
    • 0002915381 scopus 로고
    • Retroviruses
    • In, American Society for Microbiology, Washington, DC
    • Varmus HE, Brown PO, Berg DE, Howe MM. 1989. Retroviruses. In Mobile DNA, pp. 53-108. American Society for Microbiology, Washington, DC.
    • (1989) Mobile DNA , pp. 53-108
    • Varmus, H.E.1    Brown, P.O.2    Berg, D.E.3    Howe, M.M.4
  • 125
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC. 2001. The sequence of the human genome. Science 291: 1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1
  • 126
    • 0037126629 scopus 로고    scopus 로고
    • Structure of a two-domain fragment of HIV-1 integrase: Implications for domain organization in the intact protein
    • Wang JY, Ling H, Yang W, Craigie R. 2001. Structure of a two-domain fragment of HIV-1 integrase: Implications for domain organization in the intact protein. EMBO J 20: 7333-7343.
    • (2001) EMBO J , vol.20 , pp. 7333-7343
    • Wang, J.Y.1    Ling, H.2    Yang, W.3    Craigie, R.4
  • 127
    • 34547635063 scopus 로고    scopus 로고
    • HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
    • Wang GP, Ciuffi A, Leipzig J, Berry CC, Bushman FD. 2007. HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications. Genome Res 17: 1186-1194.
    • (2007) Genome Res , vol.17 , pp. 1186-1194
    • Wang, G.P.1    Ciuffi, A.2    Leipzig, J.3    Berry, C.C.4    Bushman, F.D.5
  • 129
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • Wu X, Li Y, Crise B, Burgess SM. 2003. Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
    • (2003) Science , vol.300 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 130
    • 16244386233 scopus 로고    scopus 로고
    • Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses
    • Wu X, Li Y, Crise B, Burgess SM, Munroe DJ. 2005. Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses. J Virol 79: 5211-5214.
    • (2005) J Virol , vol.79 , pp. 5211-5214
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4    Munroe, D.J.5
  • 131
    • 0034468560 scopus 로고    scopus 로고
    • Repair of gaps in retroviral DNA integration intermediates
    • Yoder K, Bushman FD. 2000. Repair of gaps in retroviral DNA integration intermediates. J Virol 74: 11191-11200.
    • (2000) J Virol , vol.74 , pp. 11191-11200
    • Yoder, K.1    Bushman, F.D.2


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