2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Wan, Chunhua ^a   Liu, Jiao ^a   Nie, Xiaoke ^a   Zhao, Jianya ^a   Zhou, Songlin ^a   Duan, Zhiqing ^a   Tang, Cuiying ^a   Liang, Lingwei ^a   Xu, Guangfei ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACETYLCYSTEINE; BETA GALACTOSIDASE; BIOLOGICAL MARKER; CELL PROTEIN; F ACTIN; GAMMA H2AX PROTEIN; PROTEIN P16; PROTEIN P21; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; ACTIN; GAMMA-H2AX PROTEIN, RAT; HISTONE; PHOSPHOPROTEIN; POLLUTANT; PRIMER DNA;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL AGING; CELL ASSAY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME ASSAY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PREMATURE SENESCENCE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALYSIS OF VARIANCE; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; FLUORESCENCE; GENETICS; METABOLISM; NERVOUS TISSUE; PC12 CELL LINE; POLLUTANT; RAT; REAL TIME POLYMERASE CHAIN REACTION; TIME; TOXICITY; WESTERN BLOTTING;

ACTINS; ANALYSIS OF VARIANCE; ANIMALS; BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL AGING; DNA DAMAGE; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FLUORESCENCE; HISTONES; HUMANS; LIPID PEROXIDATION; NERVE TISSUE; PC12 CELLS; PHOSPHOPROTEINS; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

EID: 84896069552     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089811     Document Type: Article

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