Heroin abuse accelerates biological aging: A novel insight from telomerase and brain imaging interaction

Translational Psychiatry

Volumn 3, Issue , 2013, Pages

  Cheng, G L F ^a   Zeng, H ^b,c   Leung, M K ^a   Zhang, H J ^a   Lau, B W M ^a   Liu, Y P ^d   Liu, G X ^b   Sham, P C ^a,e   Chan, C C H ^f   So, K F ^a,e,g   Lee, T M C ^a,e  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF JINAN   (China)

^c GUANGZHOU UNIVERSITY   (China)

^d GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

^e UNIVERSITY OF HONG KONG   (Hong Kong)

^f HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^g JINAN UNIVERSITY   (China)

Author keywords

Addiction; Aging; Heroin; MRI; Prefrontal cortex; Resting state; Telomerase

Indexed keywords

TELOMERASE;

ADULT; AGING; ARTICLE; ATTENTION; BEHAVIOR; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVITY; EXECUTIVE FUNCTION; GRAY MATTER; HEROIN DEPENDENCE; HUMAN; MALE; MEMORY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; WHITE MATTER; BLOOD; BRAIN; CASE CONTROL STUDY; COMPLICATION; DRUG EFFECTS; FUNCTIONAL NEUROIMAGING; PATHOLOGY; PATHOPHYSIOLOGY; DRUG EFFECT;

ADULT; AGING; BRAIN; CASE-CONTROL STUDIES; FUNCTIONAL NEUROIMAGING; HEROIN DEPENDENCE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROIMAGING; TELOMERASE;

EID: 84878654376     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.36     Document Type: Article

References (80)

1. McCarthy L, Wetzel M, Sliker JK, Eisenstein TK, Rogers TJ. Opioids, opioid receptors, and the immune response. Drug Alcohol Depend 2001; 62: 111-123. (Pubitemid 32195501)
2. Reece AS. Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers. Immun Ageing 2007; 4: 6.
3. Smyth B, Hoffman V, Fan J, Hser YI. Years of potential life lost among heroin addicts 33 years after treatment. Prev Med 2007; 44: 369-374. (Pubitemid 46550676)
4. Brugal MT, Domingo-Salvany A, Puig R, Barrio G, Garcia de Olalla P, de la Fuente L. Evaluating the impact of methadone maintenance programmes on mortality due to overdose and aids in a cohort of heroin users in Spain. Addiction 2005; 100: 981-989. (Pubitemid 40897293)
5. Oppenheimer E, Tobutt C, Taylor C, Andrew T. Death and survival in a cohort of heroin addicts from London clinics: a 22-year follow-up study. Addiction 1994; 89: 1299-1308. (Pubitemid 24310621)
6. Gronbladh L, Ohlund LS, Gunne LM. Mortality in heroin addiction: impact of methadone treatment. Acta Psychiatr Scand 1990; 82: 223-227. (Pubitemid 20329007)
7. Gruver AL, Hudson LL, Sempowski GD. Immunosenescence of ageing. J Pathol 2007; 211: 144-156. (Pubitemid 46195513)
8. Reece AS. Chronic immune stimulation as a contributing cause of chronic disease in opiate addiction including multi-system ageing. Med Hypotheses 2010; 75: 613-619.
9. Blasco MA. Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 2005; 6: 611-622. (Pubitemid 41044298)
10. Collado M, Blasco MA, Serrano M. Cellular senescence in cancer and aging. Cell 2007; 130: 223-233. (Pubitemid 47081143)
11. Epel ES. Telomeres in a life-span perspective: a new 'Psychobiomarker'? Curr Dir Psychol Sci 2009; 18: 6-10.
12. Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB et al. Extension of life-span by introduction of telomerase into normal human cells. Science 1998; 279: 349-352. (Pubitemid 28063364)
13. Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 2003; 361: 393-395. (Pubitemid 36164975)
14. Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 2004; 101: 17312-17315. (Pubitemid 39627816)
15. Epel ES, Lin J, Dhabhar FS, Wolkowitz OM, Puterman E, Karan L et al. Dynamics of telomerase activity in response to acute psychological stress. Brain Behav Immun 2010; 24: 531-539.
16. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R et al. Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response. Mol Psychiatry 2012; 17: 164-172.
17. Wolf SA, Melnik A, Kempermann G. Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia. Brain Behav Immun 2011; 25: 971-980.
18. Jacobs TL, Epel ES, Lin J, Blackburn EH, Wolkowitz OM, Bridwell DA et al. Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology 2011; 36: 664-681.
19. Burke SN, Barnes CA. Neural plasticity in the ageing brain. Nat Rev Neurosci 2006; 7: 30-40. (Pubitemid 41828929)
20. Dennis NA, Cabeza R. Neuroimaging of healthy cognitive aging. In: Craik FIM, Salthouse TA (eds) The Handbook of Aging and Cognition. 3rd edn. Psychology Press: New York, 2008. pp 1-54.
21. Reuter-Lorenz PA, Lustig C. Brain aging: reorganizing discoveries about the aging mind. Curr Opin Neurobiol 2005; 15: 245-251. (Pubitemid 41569276)
22. Grady CL, McIntosh AR, Craik FI. Age-related differences in the functional connectivity of the hippocampus during memory encoding. Hippocampus 2003; 13: 572-586. (Pubitemid 36958282)
23. Raz N, Lindenberger U, Rodrigue KM, Kennedy KM, Head D, Williamson A et al. Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. Cereb Cortex 2005; 15: 1676-1689. (Pubitemid 41447032)
24. Salat DH, Buckner RL, Snyder AZ, Greve DN, Desikan RS, Busa E et al. Thinning of the cerebral cortex in aging. Cereb Cortex 2004; 14: 721-730. (Pubitemid 38856947)
25. Eyler LT, Sherzai A, Kaup AR, Jeste DV. A review of functional brain imaging correlates of successful cognitive aging. Biol Psychiatry 2011; 70: 115-122.
26. Barnes CA. Long-term potentiation and the ageing brain. Philos Trans R Soc Lond B Biol Sci 2003; 358: 765-772. (Pubitemid 36536708)
27. Liu H, Hao Y, Kaneko Y, Ouyang X, Zhang Y, Xu L et al. Frontal and cingulate gray matter volume reduction in heroin dependence: optimized voxel-based morphometry. Psychiatry Clin Neurosci 2009; 63: 563-568.
28. Lyoo IK, Pollack MH, Silveri MM, Ahn KH, Diaz CI, Hwang J et al. Prefrontal and temporal gray matter density decreases in opiate dependence. Psychopharmacology (Berl) 2006; 184: 139-144. (Pubitemid 43083650)
29. Yuan Y, Zhu Z, Shi J, Zou Z, Yuan F, Liu Y et al. Gray matter density negatively correlates with duration of heroin use in young lifetime heroin-dependent individuals. Brain Cogn 2009; 71: 223-228.
30. Yuan K, Qin W, Dong M, Liu J, Sun J, Liu P et al. Gray matter deficits and resting-state abnormalities in abstinent heroin-dependent individuals. Neurosci Lett 2010; 482: 101-105.
31. Daglish MR, Weinstein A, Malizia AL, Wilson S, Melichar JK, Britten S et al. Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects. Am J Psychiatry 2001; 158: 1680-1686. (Pubitemid 32923662)
32. Li Q, Wang Y, Zhang Y, Li W, Yang W, Zhu J et al. Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: an event-related fMRI study. Brain Res 2012; 1469: 63-72.
33. Xiao Z, Lee T, Zhang JX, Wu Q, Wu R, Weng X et al. Thirsty heroin addicts show different fMRI activations when exposed to water-related and drug-related cues. Drug Alcohol Depend 2006; 83: 157-162. (Pubitemid 43795471)
34. Zijlstra F, Veltman DJ, Booij J, van den Brink W, Franken IH. Neurobiological substrates of cue-elicited craving and anhedonia in recently abstinent opioid-dependent males. Drug Alcohol Depend 2009; 99: 183-192.
35. Schultz W. Potential vulnerabilities of neuronal reward, risk, and decision mechanisms to addictive drugs. Neuron 2011; 69: 603-617.
36. Garavan H, Stout JC. Neurocognitive insights into substance abuse. Trends Cogn Sci 2005; 9: 195-201. (Pubitemid 40543255)
37. Lee TM, Zhou WH, Luo XJ, Yuen KS, Ruan XZ, Weng XC. Neural activity associated with cognitive regulation in heroin users: a fMRI study. Neurosci Lett 2005; 382: 211-216. (Pubitemid 40733624)
38. Volkow ND, Fowler JS, Wang GJ, Goldstein RZ. Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol Learn Mem 2002; 78: 610-624. (Pubitemid 36268682)
39. American Psychiatric Society Diagnostic and Statistical Manual of Mental Disorders DSMIV-TR. 4th edn. American Psychiatric Association Press: Washington, DC, 2000.
40. Raven JC. Standard Progressive Matrices Plus Version and Mill Hill Vocabulary Scale. Pearson Assessment: London, 2008.
41. Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res 2002; 52: 69-77. (Pubitemid 34192886)
42. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361-370. (Pubitemid 13098606)
43. Vasa M, Breitschopf K, Zeiher AM, Dimmeler S. Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res 2000; 87: 540-542.
44. Yang H, Ou CC, Feldman RI, Nicosia SV, Kruk PA, Cheng JQ. Aurora-A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells. Cancer Res 2004; 64: 463-467. (Pubitemid 38120883)
45. Ashburner J. A fast diffeomorphic image registration algorithm. Neuroimage 2007; 38: 95-113. (Pubitemid 47440133)
46. Yassa MA, Stark CE. A quantitative evaluation of cross-participant registration techniques for MRI studies of the medial temporal lobe. Neuroimage 2009; 44: 319-327.
47. Yan CC, Zang YF. DPARSF: A MATLAB Toolbox for 'Pipeline' data analysis of restingstate fMRI. Front Syst Neurosci 2010; 4: 13.
48. Song XW, Dong ZY, Long XY, Li SF, Zuo XN, Zhu CZ et al. REST: a toolkit for resting-state functional magnetic resonance imaging data processing. PLoS ONE 2011; 6: e25031.
49. Heaton KH. Wisconsin Card Sorting Test: Computer Version 4 Research Edition. PAR Psychological Assessment Resources, Inc: North Florida, 2003.
50. Eriksen BA, Eriksen CW. Effects of noise letters upon the identification of a target letter in a nonsearch task. Percept Psychophys 1974; 16: 143-149.
51. Conners CK. Conners' Continuous Performance Test II V.5. Mutli-Health Systems Inc.: Toronto, 2004.
52. Owen AM, McMillan KM, Laird AR, Bullmore E. N-back working memory paradigm: a metaanalysis of normative functional neuroimaging studies. Hum Brain Map 2005; 25: 46-59. (Pubitemid 40656192)
53. Owen AM, Sahakian BJ, Semple J, Polkey CE, Robbins TW. Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia 1995; 33: 1-24.
54. Benton AL, Sivan AB, Hamsher KS, Varney NR, Spreen O. Contributions to Neuropsychological Assessment. Oxford University Press: New York, 1994.
55. Goldstein RZ, Volkow ND. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci 2011; 12: 652-669.
56. Ersche KD, Fletcher PC, Lewis SJ, Clark L, Stocks-Gee G, London M et al. Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. Psychopharmacology (Berl) 2005; 180: 612-623. (Pubitemid 41317858)
57. Rajah MN, D'Esposito M. Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory. Brain 2005; 128: 1964-1983. (Pubitemid 41253265)
58. Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 2007; 8: 700-711. (Pubitemid 47283145)
59. Raichle ME, Mintun MA. Brain work and brain imaging. Annu Rev Neurosci 2006; 29: 449-476. (Pubitemid 44476853)
60. Kringelbach ML, Rolls ET. The functional neuroanatomy of the human orbitofrontal cortex: evidence from neuroimaging and neuropsychology. Prog Neurobiol 2004; 72: 341-372. (Pubitemid 38626161)
61. Ochsner KN, Gross JJ. The cognitive control of emotion. Trends Cogn Sci 2005; 9: 242-249. (Pubitemid 40615112)
62. Lee TM, Pau CW. Impulse control differences between abstinent heroin users and matched controls. Brain Inj 2002; 16: 885-889. (Pubitemid 35173940)
63. Pau CW, Lee TM, Chan SF. The impact of heroin on frontal executive functions. Arch Clin Neuropsychol 2002; 17: 663-670. (Pubitemid 35292279)
64. Kim S, Lee D. Prefrontal cortex and impulsive decision making. Biol Psychiatry 2011; 69: 1140-1146.
65. Ma N, Liu Y, Li N, Wang CX, Zhang H, Jiang XF et al. Addiction related alteration in restingstate brain connectivity. Neuroimage 2010; 49: 738-744.
66. Denburg NL, Cole CA, Hernandez M, Yamada TH, Tranel D, Bechara A et al. The orbitofrontal cortex, real-world decision making, and normal aging. Ann N Y Acad Sci 2007; 1121: 480-498.
67. Lamar M, Resnick SM. Aging and prefrontal functions: dissociating orbitofrontal and dorsolateral abilities. Neurobiol Aging 2004; 25: 553-558. (Pubitemid 38317354)
68. Nestler EJ. Common molecular and cellular substrates of addiction and memory. Neurobiol Learn Mem 2002; 78: 637-647. (Pubitemid 36268684)
69. Robbins TW, Everitt BJ. Limbic-striatal memory systems and drug addiction. Neurobiol Learn Mem 2002; 78: 625-636. (Pubitemid 36268683)
70. Raz N, Rodrigue KM, Head D, Kennedy KM, Acker JD. Differential aging of the medial temporal lobe: a study of a five-year change. Neurology 2004; 62: 433-438. (Pubitemid 38200856)
71. Dickerson BC, Goncharova I, Sullivan MP, Forchetti C, Wilson RS, Bennett DA et al. MRIderived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiol Aging 2001; 22: 747-754. (Pubitemid 33055614)
72. Killiany RJ, Gomez-Isla T, Moss M, Kikinis R, Sandor T, Jolesz F et al. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol 2000; 47: 430-439. (Pubitemid 30194598)
73. Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hanninen T, Laakso MP et al. Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiol Aging 2004; 25: 303-310. (Pubitemid 38220965)
74. Corbetta M, Shulman GL. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 2002; 3: 201-215. (Pubitemid 135706590)
75. Field M, Cox WM. Attentional bias in addictive behaviors: a review of its development, causes, and consequences. Drug Alcohol Depend 2008; 97: 1-20.
76. Harding IH, Solowij N, Harrison BJ, Takagi M, Lorenzetti V, Lubman DI et al. Functional connectivity in brain networks underlying cognitive control in chronic cannabis users. Neuropsychopharmacology 2012; 37: 1923-1933.
77. Chao LL, Knight RT. Prefrontal deficits in attention and inhibitory control with aging. Cereb Cortex 1997; 7: 63-69. (Pubitemid 27081872)
78. Tomasi D, Volkow ND. Aging and functional brain networks. Mol Psychiatry 2012; 17, 471 549-558.
79. Caporaso GL, Lim DA, Alvarez-Buylla A, Chao MV. Telomerase activity in the subventricular zone of adult mice. Mol Cell Neurosci 2003; 23: 693-702. (Pubitemid 36970229)
80. Ersche KD, Jones PS, Williams GB, Robbins TW, Bullmore ET. Cocaine dependence: a fast-track for brain ageing? Mol Psychiatry 2013; 18: 134-135.