Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 7, 2006, Pages 2154-2159

  McClintock, Dayle ^a   Gordon, Leslie B ^b   Djabali, Karima ^a  

^a Columbia University ^*  (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Aging; Atherosclerosis

Indexed keywords

ANTIBODY; LAMIN A; MUTANT PROTEIN; PRELAMIN A; PROTEIN FARNESYLTRANSFERASE; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL; CARBOXY TERMINAL SEQUENCE; CELL AGING; CELL CYCLE; CELL MIGRATION; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DEATH; ENZYME INHIBITION; EXON; FIBROBLAST; GENE; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LMNA GENE; PREMATURE AGING; PRIORITY JOURNAL; PROGERIA; PROTEIN LOCALIZATION; RARE DISEASE; SCHOOL CHILD; SENESCENCE; SKIN BIOPSY; VASCULAR DISEASE;

AGE FACTORS; AGING, PREMATURE; ANTIBODIES; ATHEROSCLEROSIS; CELL MOVEMENT; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; FIBROBLASTS; HUMANS; LAMIN TYPE A; MUTATION; PROGERIA; SKIN;

EID: 33144478270     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511133103     Document Type: Article

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